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1 results about "Very low-density lipoprotein" patented technology
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Very-low-density lipoprotein (VLDL), density relative to extracellular water, is a type of lipoprotein made by the liver. VLDL is one of the five major groups of lipoproteins (chylomicrons, VLDL, intermediate-density lipoprotein, low-density lipoprotein, high-density lipoprotein) that enable fats and cholesterol to move within the water-based solution of the bloodstream. VLDL is assembled in the liver from triglycerides, cholesterol, and apolipoproteins. VLDL is converted in the bloodstream to low-density lipoprotein (LDL) and intermediate-density lipoprotein (IDL). VLDL particles have a diameter of 30–80 nm. VLDL transports endogenous products, whereas chylomicrons transport exogenous (dietary) products. Recently both the lipid composition and protein composition of this lipoprotein were characterised in great detail.
Application of FGA protein in improving egg production traits of chicken
This invention discloses the application of FGA protein in improving egg production in chickens, belonging to the field of genetic engineering technology. Experiments have demonstrated that the FGA gene has a significant effect on improving egg production in chickens. Experimental results show that overexpression of the FGA gene can significantly increase the levels of reproductive hormones such as follicle-stimulating hormone, luteinizing hormone, estradiol, and progesterone in chicken serum, while significantly reducing prolactin concentration. Regarding follicle development, it can significantly increase the number of small yellow follicles, reduce the number of small white follicles, and promote follicle maturation. Regarding lipid metabolism regulation, it can significantly increase the concentrations of cholesterol, triglycerides, and very low-density lipoprotein in serum. This invention reveals for the first time the molecular mechanism by which the liver-specific endocrine factor FGA regulates egg production in chickens through interstitial communication, providing a new molecular target and application strategy for improving egg production in local chicken breeds.
Owner:HENAN AGRICULTURAL UNIVERSITY