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342results about How to "No adverse side effects" patented technology

2-imidazolinylaminoindole compounds useful as alpha-2 adrenoceptor agonists

This invention involves compounds having the following structure: wherein: a) R1 is hydrogen; or alkyl; bond (a) is a single or a double bond; b) R2 and R3 are each independently selected from hydrogen; unsubstituted C1-C3 alkanyl, alkenyl or alkynyl; cycloalkanyl, cycloalkenyl; unsubstituted C1-C3 alkylthio or alkoxy; hydroxy; thio; nitro; cyano; amino; C1-C3 alkylamino or C1-C3 dialkylamino and halo; c) R4, R5 and R6 are each independently selected from hydrogen; unsubstituted C1-C3 alkanyl, alkenyl or alkynyl; cycloalkanyl, cycloalkenyl; unsubstituted C1-C3 alkylthio or alkoxy; hydroxy; thio; nitro; cyano; amino; C1-C3 alkylamino or C1-C3 dialkylamino; halo; and 2-imidazolinylamino; and wherein one and only one of R4, R5 and R6 is 2-imidazolinylamino; d) R7 is selected from hydrogen; unsubstituted C1-C3 alkanyl, alkenyl or alkynyl; cycloalkanyl, cycloalkenyl; unsubstituted C1-C3 alkylthio or alkoxy; hydroxy; thio; nitro; cyano; amino; C1-C3 alkylamino or C1-C3 dialkylamino and halo; e) the compound is not 4-(2-imidazolinylamino)indole; enantiomers, optical isomers, stereoisomers, diastereomers, tautomers, addition salts, biohydrolyzable amides and esters thereof, and pharmaceutical compositions comprising such novel compounds. The invention also relates to the use of such compounds for treating disorders modulated by alpha-2 adrenoceptors.
Owner:BOARD OF RGT UNIV OF NEBRASKA

Integral nano material with high-efficiency removing formaldehyde at room temperature and broad-spectrum long-acting antibacterial property at same time

The invention provides an integral nano material with high-efficiency completely removing formaldehyde in air at room temperature and broad-spectrum long-acting antibacterial property at same time, relating to the field of catalysis and environmental protection. The material is characterized in that: honeycomb ceramic is used as a carrier, first loaded channel silver-doped hollandite type crystalline TiO2 is used as a matrix, and a post loaded Ag-Pt alloy is used as an active component. The doped TiO2 matrix is characterized in that: the general formula can be expressed as Ag*(A)y[MzTi8-z]O16(M=Mg2+, Zn2+; A=K+, H+; x is less than or equal to 2; y is less than or equal to 2; z is less than or equal to 3), [MzTi8-z]O16 represents the composition of the TiO2 skeleton, and Ag*(A)y represents the composition of the TiO2 channel. The weight ratio of the Ag-Pt system to TiO2 is about 0-10%, wherein, the weight ratio of Ag to the Ag-Pt system is 0-100%. The integral nano material provided by the invention can completely remove formaldehyde air at room temperature and in ambient humidity, has long-acting, high efficiency and stable broad-spectrum antibacterial property, capable of being widely used for preparing various air purifiers and microbiological treatment devices.
Owner:唐幸福 +1

Chinese medicinal preparation for treating various dermatoses

InactiveCN101979041AOvercome the Difficulties in Treating Skin Diseases by TypeReduce exudationAnthropod material medical ingredientsDermatological disorderCuticleToxic material
The invention discloses a Chinese medicinal preparation for treating various dermatoses, which is prepared from 21 Chinese medicaments such as cortex dictamni, erythrina indica lam and the like capable of promoting blood circulation by removing blood stasis and promoting circulation of qi and to relieve pain. The Chinese medicinal preparation has a unique formulation and precise and appropriate compatibility, has the effects of dispelling wind to nourish blood, removing dampness to relieve itching and cooling blood to remove toxic materials, has no bad adverse effects for clinical application, has a wide treatment range, overcomes the difficulties in grouping treatment of the dermatoses by using Chinese medicines and western medicines, and has significant curative effect of treating various dermatoses such as psoriasis, neurodermatitis, eczema, hives and acne which mainly causes epidermal hyperplasia, skin sichenification, inflammation of cuticula or a derma shallow layer, and vascular reactive and obstructive folliculus pili steatadenitis. After the prescription is taken for 7 days, itching disappears, lesion parts such as papula and maculopapule are gradually fade away, erythema and wheal disappears, exsudation is reduced, and squamae become thinner or fall off; after 14 to 21 days, the papula and the maculopapule disappears, the squamae are reduced, the sichenification disappears to achieve clinical healing; and after 28 to 35 days, skin lesions return to normal and are difficult to have a relapse.
Owner:焉曰义

High-efficiency monatomic silver nanowire antibiotic material

The invention relates to a high-efficiency monatomic silver nanowire antibiotic material which is characterized in that the monatomic silver nanowire of the antibiotic material extends from the orifice of a framework-doped manganese dioxide molecular sieve into a hole. The manganese dioxide molecular sieve is characterized by being of a hollandite type crystal structure; and the hole contains the monatomic silver nanowire or / and A ions (A=K<+>, Na<+> or H<+>). The chemical general formula can be expressed as Agm(A)n[MxMn8-x]O16 (M=Mn<2+> / <3+>, Zn<2+> and Ti<4+>; A=K<+>, Na<+> or H<+>; m<=3; n<=2; and x<=2), [MxMn8-x]O16 represents the framework composition of the manganese dioxide molecular sieve, and Agm(A)n represents the hole composition of the manganese dioxide molecular sieve. By mainly using the sterilization mechanism of catalytic activated oxygen, silver of the monatomic silver nanowire antibiotic material is not consumed in the sterilization process. Based on the synergetic effect of the quantized monatomic silver nanowire and the hollandite type manganese dioxide molecular sieve, the antibiotic material has extremely high oxygen activation performance, thereby leading to long-acting, high-efficiency and stable broad-spectrum antibiotic capability and having no adverse side effect on a human body. Thus, the antibiotic material can be widely used for preparing various antibiotic products such as paint, plastic, rubber, textile and the like.
Owner:唐幸福

Chinese herbal medicinal formaldehyde and foreign smell removing agent and preparation method thereof

Disclosed are a Chinese herbal medicinal formaldehyde and foreign smell removing agent and a preparation method thereof. The Chinese herbal medicinal formaldehyde and foreign smell removing agent is characterized by mainly consisting of following raw materials including, by weight, from 5 to 10 parts of spikenard, from 20 to 30 parts of moxa leaves, from 8 to 10 parts of thyme, from 20 to 25 parts of lemons, from 10 to 12 parts of cortex phellodendri, from 6 to 10 parts of rhodomyrtus tomentosa, from 5 to 10 parts of lysimachia foenum-graecum hance, from 10 to 15 parts of mint and from 8 to 10 parts of radix zanthoxyli. All the raw materials in the prescription are placed in a container, are added with 900-1200 parts of water, and are stewed and filtered to obtain the Chinese herbal medicinal formaldehyde and foreign smell removing agent. The Chinese herbal medicinal formaldehyde and foreign smell removing agent and the preparation method thereof have the advantages that Chinese herbal medicines neutralize formaldehyde and foreign smell so as to eliminate the formaldehyde and the foreign smell, and really do not only cover the formaldehyde and the foreign smell generally, so that an effect of removing the formaldehyde and the foreign smell is achieved, a sterilizing effect is also realized, and the Chinese herbal medicinal formaldehyde and foreign smell removing agent does not contain any chemical raw materials, does not pollute environments, is safe and non-toxic, and does not cause side effects when directly contacting with human bodies.
Owner:柳州华力家庭品业股份有限公司

A kind of traditional Chinese medicine composition for treating periodontitis

The invention discloses a Chinese medicinal composition for treating periodontitis. Traditional Chinese medical science considers that the periodontitis belongs to the category of 'gingival atrophy' and 'toothache', and the pathogenesis is excessive pathogenic fire or hyperactivity of deficiency fire. Clinical researches conducted by the hospital in recent years indicate that on the basis of the therapeutic principle of clearing stomach and reducing pathogenic fire, detoxicating and reliving swelling, cooling blood and stopping bleeding, eliminating blood stasis and dredging collaterals and nourishing yin and tonifying kidney, the Chinese medicinal composition has a good treatment effect. Decoction is prepared from bupleurum, golden thread, liquoric root, Mongolian dandelion herb, platycodon root, Szechuan lovage rhizome, Chinese arborvitae twig, cortex moutan, peach seed, Chinese angelica, white paeony root, prepared rehmannia root, cinnamomvine and medlar. Clinical trials prove that: the cure rate is 82.4 percent, the effective rate is 96.3 percent and is obviously higher than that of a control group. In addition, the Chinese medicinal composition does not have toxic or side effect, and is high in anti-inflammatory capacity, quick in detumescence and safe and reliable in a curative effect.
Owner:张安美

Catalysis technique for high-efficiency, moisture-resistance and room-temperature formaldehyde removal

The invention provides a catalysis technique for high-efficiency, moisture-resistance and room-temperature formaldehyde removal and relates to the field of catalysis and environment protection. The technique is characterized in that: a honeycomb ceramic is used as a carrier, first-loaded hollandite type crystalline manganese dioxide with silver-doped pores is used as a substrate, and second-loaded platinum (Pt) is used as an active component. The doped hollandite type crystalline manganese dioxide substrate is characterized in that: the general chemical formula is represented by Agx(A)y[MzMn8-z]O16; M may be Mg<2+>, and Zn<2+>; A may be K<+> and H<+>; x is less than or equal to 2; y is less than or equal to 2; z is less than or equal to 3; [MzMn8-z]O16 represents the skeleton composition of the hollandite type MnO2; AND Agx(A)y represents the pore composition of the MnO2. The weight ratio of Pt to doped MnO2 ranges from 0 to 10 percent. The integrated catalyst provided by the invention can be used for stably and radically removal formaldehyde from the air with high efficiency in a real environment at normal temperature and normal humidity; the integrated catalyst does not exert any adverse and side effects on human bodies and can be widely used in the preparation of various air purifier for removing formaldehyde.
Owner:上海复翼环保科技有限公司
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