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4results about How to "No adverse side effects" patented technology

A myceliopthora thermophila rice fermentation extraction compound, and a preparation method and application thereof

ActiveCN118384240Bpromote wound healingPromote wound healing and repair
The application discloses a kind of Ampelomyces quisqualis rice fermentation extraction compound and preparation method and application thereof, its preparation method is: preparation Ampelomyces quisqualis seed liquid;Preparation rice fermentation medium, Ampelomyces quisqualis seed liquid is used to ferment medium, under 22±2 ℃, natural fermentation 5~60 days, after drying, fermentation dry material is obtained for future use;After sieving, fermentation dry material is crushed and added with water, after heating reflux, centrifugation and filtration supernatant, Ampelomyces quisqualis rice fermentation extract is obtained;Hyaluronic acid or sodium hyaluronate is added to Ampelomyces quisqualis rice fermentation extract, and the compound is obtained after swelling and drying.The application is formed by Ampelomyces quisqualis rice fermentation extract and hyaluronic acid (sodium), and the polymer grid can be synergized and quickly anti-inflammatory and promote wound healing, especially promote the regeneration of normal skin appendages such as hair follicle to heal, effectively improve the repair and cure effect on various skin and mucosa damage, and has no negative effect.
Owner:NANJING UNIV OF TRADITIONAL CHINESE MEDICINE +1

An inducer for improving female flower differentiation of xanthoceras sorbifolia bunge and its preparation method and application

PendingCN122498514AIncrease the number of differentiationsIncrease the proportionGrowth plantFruit set
This invention belongs to the field of plant growth regulator technology, and relates to an inducer for improving female flower differentiation in *Xanthoceras sorbifolium*, its preparation method, and its application. The inducer, calculated per liter of aqueous solution, comprises 150-1200 mg of 6-benzyladenine, 10-50 mg of salicylic acid, 100-300 mg of choline chloride, 1.0-5.0 g of urea, 2.0-3.0 g of potassium dihydrogen phosphate, 0.5-2.0 g of boric acid, and 0.5-1.0 mL of emulsifier. This invention constructs a multi-component synergistic system for the directional regulation of flower bud sex differentiation, significantly increasing the number and proportion of female flowers in *Xanthoceras sorbifolium*, and reducing the flower bud abortion rate. Simultaneously, it improves the receptivity of the stigma of female flowers and the subsequent fruit setting rate, increasing yield per unit area, solving the industrial problem of "one fruit per thousand flowers" in *Xanthoceras sorbifolium*, and meeting the core needs of high-yield and high-efficiency cultivation and large-scale industrial development of *Xanthoceras sorbifolium*.
Owner:XINJIANG ACADEMY OF FORESTRY SCI

A production system and production method for steelmaking powder granular material packaging products

The present invention discloses a production system and a production method for packaging products for steelmaking powder and granular materials, and belongs to the field of metallurgical technology. The production system of the present invention includes an extrusion molding mechanism, a distributor, a closed welding mechanism and a flying shear, wherein the extrusion molding mechanism is used to process the steel strip to be processed into a U-shaped trough body, the distributor is used to fill the material into the U-shaped trough body; the closed welding mechanism is used to process the filled U-shaped trough body into a tube body structure with one end closed; the flying shear is used to shear and seal the tube body structure into multiple monomer sealed products. The production method of the present invention is to use the device of the above system to continuously load, seal and cut the powder and granular materials for steelmaking at its processing preparation site, so as to obtain high-strength, high-sealing and high-durability miniature monomer products, so that the packaging of the powder and granular materials for steelmaking is efficient, tightly sealed, high-density and durable, and effectively realizes the logistics process and completes the metallurgical function.
Owner:MAANSHAN XINGDA METALLURGICAL NEW MATERIAL

Construction and application of salmonella choleraesuis three-gene deletion strain without resistance marker

PendingCN119662505Alow toxicityno adverse side effectsAntibacterial agentsBacteriaNutritionIsomerase
The invention discloses a salmonella choleraesuis three-gene deletion strain without a resistance marker, wherein the preservation number of the salmonella choleraesuis three-gene deletion strain is CCTCC (China Center For Type Culture Collection) M 20242059. The strain successively lacks a virulence regulating gene crp, an important nutrition metabolism gene asd for mediating diaminopimelic acid (DAP) synthesis, and an important carbon metabolism gene manA for mediating and coding mannose-6-phosphate isomerase. The salmonella choleraesuis gene deletion mutant strain is constructed by adopting a suicide vector and SacB reverse inheritance, and a non-resistant three-gene deletion mutant strain is obtained. The three-gene deletion mutant strain is clear in genetic background, free of resistance markers, good in safety and immunoprotectiveness to mice and capable of helping the mice to resist attack of high-lethal-dose salmonella choleraesuis, as the asd gene in the deletion strain is completely deleted in a traceless mode, a balanced lethal system plasmid pya3493-ApxIAN is electrically transformed into the deletion strain, and therefore the expression of the salmonella choleraesuis in the high-lethal-dose salmonella choleraesuis in the high-lethal-dose salmonella choleraesuis. The recombinant strain not only can grow in a DAP-free culture medium, but also can stably express foreign protein ApxIAN, and has a wide application prospect.
Owner:LANZHOU VETERINARY RESEARCH INSTITUTE CHINESE ACADEMY OF AGRICULTURAL SCIENCES(LANZHOU BRANCH CENTER OF CHINA ANIMAL HEALTH & EPIDEMIOLOGY CENTER)