260 results about "Impaired memory" patented technology

A dispersing oxiracetam tablet for preventing senile dementia and treating hypomnesia is prepared from oxiracetam, disintegrant,lubricant, flowing aid and adhesive through proportionally and sequentially mixing, granulating, baking and tabletting. Its advantage is high curative effect.

The present invention discloses a balanced nutrient tea and beverage. Its raw material composition includes (by weight portion) 0.5-3 portions of American ginseng, 1-3 portions of sterculia, 2-5 portions of dried longan flesh, 2-5 portions of dried jujube, 2-5 portions of dried apricot flesh, 1-3 portions of spiny jujube kernel, 1-4 portions of lyceum berry, 2-5 portions of raisins, 1-3 portions of tea, 0.5-3 portions of lonicera flower, 0.5-2 portions of notoginseng flower and 1-15 portions of honey. Said invention contains several nutrient components of vitamins, amino acids, saponin, mineral and organic acid, etc. and has several health-care functions of raising immunity of human body, etc.

This invention pertains to apparatus methodology formulated to perform electromagnetic brain animation (EBA) for the purpose of partial or complete alleviation of specific mental impairments relating categorically to infant, early childhood, and adolescent target populations. EBA expressly refers to an original system and mechanized manner for determining and redirecting particular areas of the brain found to suffer from endemic and/or environmental injury. Electromagnetic brain animation is an enhanced initiative for positive influence on brain region neuron activity with the impetus to habilitate, rehabilitate and/or redirect dysfunctional cellular structure in direct correlation with greater pliability of evolving nervous systems in conjunction with superior biological plasticity due to specified group cluster. The EBA technical inclination, evolution and fruition of “animation” are specifically related to safety and success with early developing brains. Special areas targeted, but not limited to, include depression, dysthymia, attention deficit disorder, learning disability, memory loss, overanxious disorder, mild retardation, and autism.

Benzopyranone compounds having the following structure: wherein R1, X, Y and n are as defined here, are disclosed. The compounds of formula (I), wherein R1 is H, can be prepared by demethylation of the corresponding phenolic methyl ether. The compounds are useful for treating a bone-resorbing disease, cancer, arthritis or an estrogen-related condition such as breast cancer, osteoporosis, endometriosis, cardiovascular disease, hypercholesterolemia, prostatic hypertrophy, prostatic carcinomas, obesity, hot flashes, skin effects, mood swings, memory loss, and adverse reproductive effects associated with exposure to environmental chemicals or natural hormonal imbalances.

The invention discloses a new traditional Chinese medicine composition for treating nephrotic syndrome and a preparation method thereof. The traditional Chinese medicine composition mainly comprises the following Chinese medicinal herbs such as American ginseng, ginseng, codonopsis pilosula, unprocessed astragalus mongholicus, Chinese yam, turtle shell, tortoise plastron, cornu cervi degelatinatum, fruit of Chinese wolfberry, root of Chinese trichosanthes, fruit of Chinese magnoliavine, seed of Chinese dodder, herba cistanche, Chinese caterpillar fungus, prepared rehmannia root, polygonum multiflorum, fructus ligustri lucidi, dried orange peel, myristica fragrans, fructus amomi, semen euryales, mangnolia officinalis, fructus chebulae, fructus rosae laevigatae, fructus alpiniae oxyphyllae, oyster, drynaria rhizome, dogwood, root-bark of Chinese wolfberry, phellodendron, fructus gardenia, white atractylodes rhizome, lucid asparagus, ophiopogon japonicus, herba epimedii, rhizoma anemarrhenae, root of kudzu vine and the like. The traditional Chinese medicine composition can be prepared into any one common oral preparation according to a conventional traditional Chinese medicine preparation method. The invention can remarkably improve symptoms of proteinuria, hypoalbuminemia, hematuresis, generaldropsy, listlessness, poor physical strength, inappetence, insomnia and amnesia, hypomnesis and the like of the patients suffering from the nephrotic syndrome and has accurate clinical treatment effect, remarkable treatment effect and rapid effect taking. Because of being combined by basically adopting medicinal and edible medicines specified in National Formulary, the invention has the advantages of low cost, basically no toxic and side effects and the like.

The invention discloses a new traditional Chinese medicine composition for treating memory loss and a preparation method thereof. The traditional Chinese medicine composition mainly comprises the following raw medicinal herbs: fructus alpiniae oxyphyllae, rhizoma acori graminei, dangshen, angelica sinensis, raw astragalus mongholicus, ginseng, radix paeoniae alba, root of common peony, ligusticum wallichii, radix salviae miltiorrhizae, chrysanthemum, root of kudzu vine, radix angelicae, prepared rehmannia root, motherwort, rhizoma sparganii, curcuma zedoary, cortex albiziae, polygala tenuifolia, styrax Asiatic styrax, white atractylodes rhizome, aweto, scutellaria baicalensis, polygonum multiflorum, red flower, radix curcumae and fruit of Chinese wolfberry. The traditional Chinese medicine composition can be prepared into any one oral preparation according to a conventional traditional Chinese medicine preparation method. The invention can remarkably improve symptoms of hypomnesis, thinking logic disorder and incomplete language expression as well as memory loss, no recognition of family and relatives and friends, no capability of self-care life, changeable and violent characters in serious conditions, or dull spirit and the like, and has accurate clinical treatment effect, remarkable treatment effect and rapid effect taking.

The invention thus pertains to the use of a composition comprising: (a) uridine or uridine phosphate; and (b) docosahexaenoic acid and/or eicosapentaenoic acid, for improving memory and/or the treatment or prevention of impaired memory function, in a subject with a mini-mental state examination of 24-26, wherein said composition is enterally administered to the subject. In the MMSE test, any score of 27 or higher (out of 30) is effectively normal. In the patients with dementia, 20-26 indicates mild dementia, 10-19 moderate dementia, and below 10 severe dementia. It was the present inventors' belief that within the group of 20-26, the memory impairment in the sub-group of 24-26 may even be reversible, as the pathological pathways have just started to develop. In this group of subjects the pathological pathways have just started to develop. Clinical studies show excellent results for this subgroup.

The invention discloses a new external Chinese medicinal composition for treating hydrocephalus and a preparation method thereof. The Chinese medicinal composition mainly comprises the following raw material medicaments: szechuan lovage rhizome, grassleaf sweelflag rhizome, manchurian wildginger, incised notopterygium rhizome, fineleaf schizonepeta herb, divaricate saposhnikovia root, cassia twig, Chinese ligusticum rhizome, angelica dahurlica, kudzuvine root, flos chrysanthemi, baical skullcap root, ash bark, lightyellow sophora root, radix scrophulariae, red paeony root, giant knotweed rhizome, natural indigo, vietnamese sophora root, Indian buead, Chinese lobelia herb, cortex lycii radicis, rhubarb, akebia stem, oriental waterplantain rhizome, plantain seed, India madder root, cattail pollen, rosewood heart wood, peach seed, safflower, root of red-rooted salvia, common burreed rhizome, zedoary, ground beeltle, storax, borneol, camphor, toad venom, musk, benzoin, sandalwood, mint, pubescent angelica root, beautiful sweetgum fruit, radix stephaniae tetrandrae, glandularstalk St paulswort herb, cortex acanthopanax radicis, swordlike atractylodes rhizome, herba agastachis, cortex magnoliae officinalis, talc, manshurian dutchmanspipe stem, ricepaperplant pith, Japanese climbing rern spore, pyrrosia leaf, longhairy antenoron herb, prepared common monkshood daughter root, costustoot, cyperus rotunus, szechwan chinaberry fruit, pangolin scales and the like. The Chinese medicinal composition can be prepared into any external preparation used commonly according to the conventional method of Chinese medicinal preparations. The external Chinese medicinal composition can improve symptoms such as increased intracranial pressure, pain of bilateral tempus or whole skull, nausea, cephaloedema or optic atrophy, mental retardation, dyskinesia, phenomena from slow walk and disequilibrium to incapability of walking and finally ill-health in beds, dysphrenia and hypomnesis.

The present invention relates to the use of an hydroxylated stilbene, in particular resveratrol, in the manufacture of a neutraceutical composition for increasing the mi- crovascular plasticity and/or microvessel density, and/or decreasing the microvessel abnormalities in the brain, in particular in the hippocampus of a mammal, in particular for the treatment of age- and condition-related decline in brain neuronal function and/or cognitive functioning in a mammal. In particular, the condition is selected from the group of Alzheimer's Disease, dementia, depression, sleep disorders, impaired memory function, psychoses, Parkinson's disease, Huntington's chorea, epilepsy, schizophrenia, paranoia, ADHD and anxiety.

The invention discloses a novel traditional Chinese medicine composition for treating senile dementia and a preparation method thereof. The traditional Chinese medicine composition mainly comprises the following raw materials: sharpleaf glangal fruit, fleeceflower root, Astragali radix, angelica, white peony root, Radix codonopsitis, Chinese yam, grassleaf sweetflag rhizome, incised notopterygium rhizome, malt, tambac, immature orange fruit, dried tangerine peel, nutgrass galingale rhizome, prepared rehmannia root, szechwan lovage rhizome, dahurian angelica root, danshen root, motherwort herb, albizzia, Cordyceps sinensis, stemona root, Cassia occidentalis, pearl, Styrax, Benzoin, holy basil, borneol, camphor and the like. The traditional Chinese medicine composition can be prepared into any one normally used oral preparation according to the conventional method of traditional Chinese medicine preparations. The invention can obviously improve the symptoms of dull expression, lags in response, stoit, hypomnesis, ambiguous pronunciation of words, incoherence, even incontinence, no ability to take care of oneself, paralysis and the like, and has obvious clinical curative effect, significant curative effect and rapid effect. The invention has the advantages of low cost, basically no toxicity and side effects and the like.

The present invention relates to a preparation mainly for preventing and curing the diseases of tonicity, dysphoria, lassitude, light-headedness, hypomnesis and female premenstrual syndrome. It is characterized by that said preparation contains gamma-aminobutyric acid and theanine. Besides, in said preparation the medicinal plant, amino acid, vitamin, mineral and auxiliary material which can be used as additive in food or medicine also can be added.

The invention provides a hygienic grape wine which comprises 14 Chinese medicinal herbs including tuber of multiflower knotweed, lotus seeds, lysimachia christinae, mulberry seeds, cherokee rose, ligustrum japonicum, dodder seed, achyranthes and cyathula root, mulberry, red date, matrimony vine, prepared rhizome of rehmannia, astragalus root, cinnamon.

The invention discloses a tincture having treating and adjusting health-care effects, which relates to a Chinese medicinal preparation. The tincture consists of mint (fried), borneol, poria extract, eucommia bark, desertliving cistanche, medicinal indianmulberry root, barbary wolfberry fruit (fried), south dodder seed, dogwood fruit (washed with wine), Chinese angelica (fried), codonopsis pilosula, rehmanniae vaporata, longspur epimedium, cloves, bark, tuber onion seed, glossy privet fruit, cinnamon, flos inulae, common curculigo rhizome, Chinese magnoliavine fruit, common cnidium fruit, Chinese wild ginger (fried), spina date seed, tuberculate speranskia herb (fried), dahurian angelica root (fried), goat bone and lavender. The tincture is prepared by the following steps of: soaking, cutting and airing the 28 Chinese herbal medicines and animal parts; coarsely treating the mixture; putting the coarse mixture into a container; adding 10 kilograms of 95 percent edible alcohol and 2.5 kilograms of purified water; stirring uniformly once every 1 to 2 days; sealing at any time; opening the container after soaking for 30 days; filtering residues to obtain a finished product; and bottling the tincture for later use. The tincture has the advantages of adopting a transdermal treatment method for externally curing an internal disease, acting good treating and adjusting health-care effects on hypomnesis, neurasthenia, hypodynamia, senile dementia and diseases such as impotence, premature ejaculation, spermatorrhea, abnormal sweating due to decreased sexual functions and the like, resisting premature senility and prolonging life.

The invention provides a method for preparing Oxiracetam, which comprises the following steps: performing alkaline treatment of 4-hydroxy-2-pyrrolidone under a water-free condition; reacting the treated 4-hydroxy-2-pyrrolidone with 2-chloroacetamide in an organic solvent in the presence of a catalyst; and after the reaction is finished, performing filtration, distillation and recrystallization to obtain the Oxiracetam. In the method, the final product can be obtained by a one-step reaction, the operation is simple and convenient, and large scale production can be realized. The invention also provides the Oxiracetam obtained by the method, which has the characteristics of high yield, high purity and good treatment effect. The invention also provides the use of the Oxiracetam obtained by the method in the preparation of medicaments for treating brain dysfunction, impaired memory and senile dementia.

The invention discloses an intelligence-promoting capsule for improving memory and a preparation method thereof. The content of the intelligence-promoting capsule consists of the following components in parts by weight: 20-50 parts of goat fetus and placenta, 10-20 parts of multiflower knotweed tuber, 10-20 parts of Chinese magnoliavine fruit, 8-16 parts of thinleaf milkwort root-bark, 8-16 parts of grassleaf sweelflag rhizome, 6-16 parts of Szechuan lovage rhizome and 6-16 parts of red-rooted salvia root. The capsule is prepared by performing ultrafine grinding on the goat fetus and the placenta, performing water extraction and concentration on other medicinal materials and performing spray drying. The Chinese medicinal capsule is prepared on the basis of the traditional Chinese medicine health theory, is scientific and reasonable in formula, simple in preparation process, safe, stable and effective, has the functions of promoting intelligence and improving memory, and is suitable for senile dementia patients and other people with hypomnesia.

The invention provides a composition with the effects of refreshing and restoring consciousness. The composition is prepared from the following raw materials in parts by weight: 1-5 parts of peppermint essential oil, 2-8 parts of lemon essential oil, 1-5 parts of cassia twig essential oil, 1-5 parts of wild chrysanthemum flower essential oil and 2-8 parts of grassleaf sweelflag rhizome essential oil. The invention also provides application of the composition. Formulated essential oil provided by the invention has relatively good effects on diseases such as dispiritedness, concentration decrease and memory deterioration caused by various physical discomfort; although single-component essential oil has a refreshing effect, the application scope of a single component is relatively narrow; and the compound essential oil has better effects in the aspects of refreshing and restoring consciousness, and is also conductive to reliving the spirit drooping and dispiritedness state caused by different reasons.

The present invention provides compounds of the general formula (I)

wherein X, n and R¹ are as described herein, as well as pharmaceutically acceptable salts and esters thereof, methods for their manufacture, pharmaceutical compositions containing them and their use as medicaments. The active compounds of the present invention are dual modulators of the serotonin 5-HT_2a and dopamine D₃ receptors, useful in the treatment and/or the prevention of cognitive disorders, drug addiction, depression, anxiety, drug dependence, dementias, memory impairment, psychotic disorders comprising schizophrenia, schizoaffective disorders, bipolar disease, mania, psychotic depression, and psychoses comprising paranoia and delusions.

The present invention relates to a health care wine, in particular to a health care wire which contains the traditional Chinese medicine for nourishing yin, the existing health care wines are mostly the wines for strengthening yang, which can cause the imbalance between yin and yang by excessive drinking; China has a word that yang mainly controls the organs and yin mainly controls body fluids, the excess of yang often causes qi stagnation and blood stasis, so as to cause cardiovascular diseases, hearing loss, memory impairment and alopecia. The components of the present invention include: beverage wine, each 1000 parts by weight of the beverage wine is added with 30 parts of radix rehmanniae glutinosae, 30 parts of radix rehmanniae preparata, 20 parts of common yam rhizome, 20 parts of common macrocarpium fruit, 20 parts of barbary wolfberry fruit, 15 parts of glossy privet fruit, 15 parts of tree peony bark, 20 parts of hawthorn fruit, 30 parts of tuber fleeceflower root, 30 parts of salvia, 30 parts of membranous milkvetch root, 20 parts of Chinese magnoliavine fruit, 15 parts of oriental waterplantain rhizome, 15 parts of Indian buead and 15 parts of kudzuvine root, and all the components are soaked for 25 to 40 days and then the wastes are removed. The product can be used as the health care wine for the treatment of age related hearing loss, alopecia, bad memory and the improvement of the cardiovascular adverse states.

The invention discloses a maca dunaliella salina compound preparation. The maca dunaliella salina compound preparation comprises dunaliella salina and spirulina and is prepared from the following materials: 3-10 percent of dunaliella salina, 40-45 percent of spirulina and 45-55 percent of maca. The maca dunaliella salina compound preparation has the effects of building body and tonifying Yang, curing organs, maintaining beauty and keeping young and improving the digestive system, achieves a two-way blood-pressure regulating function, as well as a two-way blood sugar regulating and balancing function, can regulate body metabolism and resist aging, tumor and fatigue and enhance the immunity, and has remarkable effects on cardio-cerebrovascular diseases, chronic diseases, senile dementia, climacteric syndrome and the like. When drunk frequently, the maca dunaliella salina compound preparation increases sexual intercourse, keep youth for a long time and prolongs the lifetime, has the advantages of relaxing tendons and activating collaterals, activating blood circulation to dissipate blood stasis, dispelling wind to eliminate dampness and strengthening bones and tendons and can remarkably improve memory.

The invention discloses health maintenance biscuits and a making method thereof. The health maintenance biscuit is made from main raw materials, including, low-gluten flour, Chinese yam, red dates, mushroom extractives and nuts, and auxiliary materials; the mushroom extractives are obtained by extracting the raw materials, including, monkey head mushrooms, Chinese mushrooms and termjte mushrooms. The obtained health maintenance biscuits are rich in date flavor and crispy, and has effects of promoting intelligence growth, invigorating the spleen and increasing the appetite, as well as enhancing nutrition, is particularly suitable for office workers with great work pressure, students with learning stress and old people with hypomnesis to eat.

A Chinese medicine in the form of micropill, tablet, dispersing tablet, dripping pill, or particle for treating headache, dizziness, hypomnesia, insomnia, tinnitus, etc is prepared from 6 Chinese-medicinal materials including gastrodia tuber, earthworm, grass-leaved sweetflag rhizome, rehmannia root, etc. Its preparing process and quality control method are also disclosed.

The invention discloses a traditional Chinese medicine composition for protecting a liver and dispelling effects of alcohol. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicine ingredients in parts by weight: 40-50 parts of root of kudzu vine, 20-25 parts of oriental wormwood, 40-50 parts of momordica grosvenori, 50-58 parts of pericarpium citri reticulatae and 0.5-1.5 parts of menthol. The traditional Chinese medicine composition has the effects of clearing away heat and toxic materials and inducing dieresis, soothing the liver and benefiting bile, strengthening the spleen, harmonizing the stomach and tonifying qi, and protecting the liver and dispelling effects of alcohol. As to the sufferer with nausea, vomiting, hypomnesis, inattention, liver injury and the like caused by drinking too much, the traditional Chinese medicine composition can play the roles of quickly, safely and effectively protecting the liver and dispelling effects of alcohol.

The invention discloses stachyose-containing maca tablet candy and maca tablets, belonging to the field of food. The stachyose-containing maca tablet candy and maca tablets are prepared from 46-83% of 10,000-mesh maca superfine powder and 15-52% of stachyose with purity of 75-98%. The stachyose prepared from Stachys floridana, herba lycopi, Yintiaocai, Chinese artichoke, Thlaspi arvense, beans, radix rehmanniae and the like is adopted. The stachyose-containing maca tablet candy and maca tablets are prepared by the following steps of purifying, washing, cutting, drying and coarsely crushing fresh maca; crushing into superfine powder of 8,000-12,000 mesh at a temperature lower than 60 DEG C; mixing the raw materials according to the formula, adding 30-50wt% of ethanol with purity of 90% for wetting, granulating and drying; adding 1-2% of magnesium stearate, tableting and packaging. With complete nutrition, the maca product is easy to digest and absorb, improves the functions of the reproductive system, can adjust the intestinal microecological balance, reduce the cholesterol and improve the immunity, does not rely on the insulin metabolism, promotes the absorption of the trace elements such as Ca, Mg and the like, delays the forgetfulness, prevents dental caries, and is particularly suitable for women, diabetes, obese people, 'three-high' people and old people.