80results about How to "Achieve antibacterial effect" patented technology

The invention relates to the field of essential oil slow release, and discloses a mildew-proof tablet containing plant essential oil and a preparation method and application thereof.The mildew-proof tablet containing the plant essential oil comprises two epidermal layers and an essential oil slow-release layer arranged between the two epidermal layers, the preparation method comprises the following steps: grafting sodium abietate and aminated mesoporous silica to prepare functionalized mesoporous silica, loading plant essential oil on the functionalized mesoporous silica to obtain a core material, introducing dihydroxyl polyhedral oligomeric silsesquioxane into a polyurethane main chain, wrapping the core material to prepare an essential oil slow-release agent, taking lignin as a base material, taking the essential oil slow-release agent as an effective component, and preparing the essential oil slow-release agent. And preparing to obtain the essential oil slow-release layer. The prepared essential oil slow-release layer can achieve the effects of essential oil slow release and antibiosis and mildew prevention, the slow-release effect is remarkable under the normal-temperature and high-temperature conditions, the good slow-release effect is still kept in the humid environment, and the efficacy period of the material is greatly prolonged.

The invention discloses manganese and cerium co-doped modified sodium niobate, which is prepared from Nb2O5, MnO2, CeO2 and sodium hydroxide. The invention further discloses magnesium-based bone cement with the sonodynamic / nano-enzyme antibacterial function and the piezoelectric osteogenesis function. The magnesium-based bone cement is prepared from CaHPO4, NaH2PO4, MgO powder, hydroxyapatite and manganese-cerium co-doped modified sodium niobate. The magnesium-based bone cement with sonodynamic / nano-enzyme antibiosis and piezoelectric osteogenesis provided by the invention has piezoelectric enhanced sonodynamic and nano-enzyme synergistic antibacterial activity and piezoelectric osteogenesis activity, effectively removes bacteria / biological membranes, realizes combination of antibiosis and bone repair under different ultrasonic powers, effectively treats infectious bone defects, and has a good application prospect. The treatment effect of the MPC basal bone repair material is obviously improved.

The invention discloses a flame-retardant antistatic wear-resistant fabric and a preparation method thereof, and relates to the field of fabrics. When the flame-retardant antistatic wear-resistant fabric is prepared, nano titanium dioxide is subjected to a reaction with 3-aminopropyltrimethoxysilane, 2, 5-dihydroxy terephthalaldehyde and 1-aminopyrrole in sequence, and modified nano titanium dioxide is prepared; reacting the ester mixed solution with the alcohol mixed solution, and then reacting with 1-allyl-1H-pyrrole to obtain modified polyester; reacting the modified polyester, the modified nano titanium dioxide and a pyrrole mixed solution, spinning, and weaving to obtain the flame-retardant antistatic wear-resistant fabric. The flame-retardant antistatic wear-resistant fabric prepared by the invention has excellent flame-retardant, antistatic, wear-resistant, antibacterial and anti-aging effects.

The invention discloses quick-dry water-based ink and a preparation method thereof, and relates to the technical field of ink. The preparation method comprises the following steps: firstly, enabling 4, 6-bis (allyloxy)-n-butyl-1, 3, 5-thiazine-2-amine and vinyl sulfonamide to participate in a polymerization reaction of acrylic acid and butyl acrylate, and preparing 4, 6-bis (allyloxy)-n-butyl-1, 3, 5-thiazine-2-amine and vinyl sulfonamide through a two-step emulsion polymerization method; the core-shell structure modified polyester emulsion with 2, 5-thiazine-2-amine and vinyl sulfonamide as soft shells and acrylic acid and butyl acrylate as hard cores improves the wear resistance and durability of the ink. Then allyl polyether reacts with 2-(p-chlorphenyl) ethylene oxide, so that the drying time is shortened, and the wear resistance of the ink is improved; then through addition reaction of reactants, bis (2-ethoxyl) dimethyl ammonium chloride and hydrogen-containing silicone oil, the epoxy-amino-polyether combined modified silicone oil flatting agent is formed, the flatting agent has hydrophilicity and hydrophobicity, the drying speed is increased, and the wear-resistant effect is improved.

The invention belongs to the field of new textile materials, and discloses a mist preparation method of a Janus polyester fabric with one-way moisture conduction and antibacterial functions, which comprises the following steps: step 1, spraying and grafting an aminopropyltriethoxysilane solution to the surface of one side of the polyester fabric, washing and drying to obtain an aminated / polyester fabric; step 2, spraying a mixed aqueous solution of copper acetate and cysteine to the surface of the same side of the polyester fabric, baking, and repeating the spraying-baking operation for three times to obtain the Janus polyester fabric with the one-way moisture conduction and antibacterial functions. The problems that an existing preparation method is complex and high in energy consumption, and the prepared polyester fabric is single in function, large in skin irritation, poor in sanitary safety and the like are solved, and meanwhile the original wearing properties such as tensile strength and flexibility of the polyester fabric can be reserved.

The invention discloses an acne-removing essence and a preparation method thereof, and particularly relates to the technical field of skin care products, the acne-removing essence comprises the following components by mass: 0.5-5% of salicylic acid; 1%-5% of tartaric acid; 2%-6% of nicotinamide; 0.5%-2% of colloidal sulfur; 1.5%-3% of tea tree essential oil; 1%-2% of hyaluronic acid; 0.5%-1% of ceramide; 1%-3% of glycerol; 1%-2% of trehalose; the salicylic acid is used for penetrating into skin, helping to relieve dead skin cells, reducing inflammation and accelerating skin renewal; the tartaric acid is used for realizing a stripping effect, can remove aged cuticles on the surface of the skin and promote the generation of new cells, so that the problem of acnes is helped to be improved. The acne-removing essence prepared by the invention has a relatively good moisturizing effect, so that skin barrier can be well maintained, keratin metabolism is promoted, grease secretion is inhibited, acne is effectively prevented, inflammatory response of the acne is relieved, and the actual use effect of the acne-removing essence is relatively good.

The invention relates to the technical field of polypeptides, and discloses a soybean polypeptide with an antibacterial function and a preparation method thereof.The soybean polypeptide with the antibacterial function is obtained by adding soybean polypeptide, quaternized cholic acid and modified chitosan into N, N-dimethylformamide and stirring for reaction. A chitosan group, a quaternary ammonium salt group, an imidazole group and a cholic acid group contained in the soybean polypeptide with the antibacterial function jointly form an antibacterial system, and a good antibacterial effect is achieved; wherein the chitosan group can destroy bacterial cell walls to death bacteria, so that the antibacterial effect is achieved, and the cholic acid group also has a relatively good antibacterial effect; the imidazole group rapidly kills bacteria by destroying bacterial cell membranes, affecting bacterial metabolism and inhibiting formation of biological membranes, a good antibacterial effect is achieved, quaternary ammonium salt is adsorbed to the negatively charged bacterial cell membranes through the cationic characteristics of quaternary ammonium salt, the cell membranes are broken, and therefore the bacteria are rapidly killed.

The invention discloses a preparation method of polylactic acid fibers for medical and sanitary materials, and relates to the technical field of polylactic acid fibers. Nano-crystalline cellulose, nano-graphite particles and polylactic acid are blended and crosslinked, the mechanical property of a matrix is enhanced, the antibacterial property is achieved, fibers are prepared through spinning, supercritical carbon dioxide treatment is conducted for the first time, the nano-graphite particles can play a role of a nucleating agent, polylactic acid is promoted to form fine and uniform crystals, and the mechanical property of the matrix is improved. Carbon dioxide is effectively wrapped in the foaming process, a micropore structure is formed in the fiber, the mechanical property of a matrix is enhanced, then secondary supercritical carbon dioxide treatment is conducted, the nano-silver is loaded into the matrix through supercritical fluid, the antibacterial property and the mechanical property are further improved, then the nano-silver is soaked in a silicate solution, dehydration is conducted, and the nano-silver fiber is obtained. A silica gel layer is formed on the surface of the fiber, so that the mechanical property and the antibacterial property of a matrix are enhanced.

The invention relates to the technical field of high polymer materials, and discloses antibacterial cellulose modified polylactic acid, triazole compounds have excellent activity in the antifungal aspect, and sulfanilamide groups can influence nucleic acid metabolism of thalli and synthesis of dihydrofolic acid so as to play a bacteriostatic role. Under the synergistic effect of a sulfanilamide group and a triazole group, the synthesized antibacterial cellulose has excellent antibacterial activity, the antibacterial group is introduced in a grafting manner, so that the long-acting antibacterial activity can be maintained, the polylactic acid is modified by using the cellulose, and due to the large length-diameter ratio of the cellulose and mutual overlapping of the cellulose, the antibacterial activity of the polylactic acid is improved. A good net structure is formed in a polylactic acid matrix through hydrogen bonds and Van der Waals force, so that a toughening effect on polylactic acid can be achieved, and the modified polylactic acid not only has excellent antibacterial activity, but also has better mechanical properties and thermal stability.

The invention provides a self-assembled SDS-LC-LDH and a preparation method thereof as well as modified polypropylene and a preparation method thereof, and particularly relates to the technical field of high polymer materials. The self-assembled SDS-LC-LDH comprises a layered double metal hydroxide, and lignin and catechin which are intercalated between the layers of the layered double metal hydroxide. According to the invention, lignin and catechin are inserted between layers of layered double hydroxides (LDH) to realize the dual functions of flame retardance and antibiosis. And under a high-temperature condition, bound water and carbon dioxide between LDH layers can be released to improve the flame retardant property. Meanwhile, metal hydroxides of the LDH laminates and lignin are subjected to catalytic reaction in the thermal degradation process, a compact carbonization layer is formed, and external heat and oxygen are effectively prevented from penetrating into the material. Phenolic hydroxyl groups in catechin can interfere with normal metabolism and growth of bacteria and show antibacterial characteristics.

The invention discloses a preparation method of a blue light response fluorine-nitrogen co-doped zinc oxide antibacterial agent, relates to the technical field of dental caries repair materials, and solves the problem of secondary caries caused by the fact that a dental clinical repair material does not have an antibacterial effect. Comprising the following steps: adding a zinc nitrate hexahydrate solution containing ammonium fluoride and urea into a concentrated sodium hydroxide solution, and stirring to obtain a precursor solution; washing the precursor solution with deionized water and absolute ethyl alcohol, performing suction filtration, drying in a drying oven, and annealing to obtain fluorine-nitrogen co-doped zinc oxide; the fluorine-nitrogen co-doped zinc oxide prepared by the invention has a relatively good antibacterial effect on the main bacterium streptococcus mutans in the oral cavity, meanwhile, the fluorine-nitrogen co-doped zinc oxide shows good biocompatibility, the antibacterial effect is improved under the illumination of a dental curing lamp, and the technical problem that the existing dental composite resin cannot realize long-term bacteriostasis is solved.

The invention provides a preparation method of an antibacterial polyester fabric, which is characterized in that chitosan and graphene are taken as a core layer, Ag < + >-loaded nano staple fibers, PET and a spinning aid are taken as a skin layer, and the antibacterial polyester fabric is obtained through melt spinning and tatting spinning. The antibacterial polyester fabric prepared by the method has a network-like silver simple substance structure, the antibacterial property and the mechanical property are remarkably improved, the initial antibacterial rate to gram negative E.coli and gram positive S.aureus reaches 99.999%, the antibacterial efficiency can still reach 70% after the fabric is soaped for 35 times, and the actual use requirement of the antibacterial polyester fabric can be met.

The invention discloses a contact lens care solution capable of moisturizing, lubricating and resisting bacteria for a long time and a preparation method thereof, and the care solution comprises the following components in percentage by mass: 1.0-2.5% of polyglycerol ether-26; 2.0%-3.5% of a composite natural bacteriostatic agent; 1.0 to 2.0 percent of a thickening agent; 1.5%-2.5% of a surface active agent; 0.15%-1.8% of a pH regulator; 8.5-9.0% of an osmotic pressure regulator; and the balance of purified water. The composite natural bacteriostatic agent is a mixture of catechin and ginkgetin. The preparation method comprises the following steps: adding part of purified water into a container, then adding polyglycerol polyether-26, the composite natural bacteriostatic agent, the thickening agent and the surfactant, then supplementing part of purified water, and stirring for dissolving; adjusting the pH value of the solution to 6.5-7.8 and the osmotic pressure to 260-340 mOsm / kg.H2O, finally adding the balance of purified water, and uniformly stirring; and filtering and sub-packaging to obtain the product. According to the invention, polyglycerol ether-26 has high moisturizing and lubricating properties, catechin and ginkgetin have a synergistic effect, so that the antibacterial property can be improved, and as a natural plant extraction component, the eye cream is non-irritant when entering eyes, is higher in safety and can play a role in protecting the eyes.

The invention discloses a preparation method of an antibacterial cobalt-chromium alloy false tooth, which comprises the following steps: S1, mixing cobalt-chromium alloy powder and aluminum oxide powder in proportion, putting the mixture into an aluminum oxide crucible, and preparing composite powder by adopting a gas atomization method; s2, screening and drying the composite powder, adding the composite powder into a powder cabin of an additive manufacturing system from the top of equipment, and realizing circulating layer-by-layer powder laying and sintering through selective laser melting forming to obtain a denture matrix; s3, performing transition layer film modification on the surface of the false tooth matrix in the iron ion-doped titanium dioxide sol through a dip-coating method to obtain a transition layer modified false tooth matrix; s4, the false tooth base body modified by the transition layer is placed in a filtered cathode vacuum arc coating system to be deposited, and finally the antibacterial cobalt-chromium alloy false tooth is obtained. The antibacterial cobalt-chromium alloy has the advantages that the cobalt-chromium alloy is endowed with good antibacterial performance on the basis of ensuring good mechanical performance, and meanwhile, the antibacterial layer is high in bonding strength and longer in antibacterial duration.

The utility model provides a filter and a respirator adopting the filter, belongs to the technical field of respirators, and overcomes the defects that in the prior art, the size needed by electrostatic adsorption is large, released ozone is harmful to human bodies and the like. The high-oxygen membrane particles have no secondary pollution and no ozone release pollution, and are safe; and the device has the characteristics of low resistance, low power consumption, long-acting and stable sterilization effect and the like.

The invention relates to the technical field of high polymer materials, in particular to a preparation method of antibacterial hydrogel for infectious diabetes wound healing, chitosan and tobramycin are used as dynamic physical cross-linking agents, and the hydrogel is prepared through free radical polymerization of N-acryloyl triester (hydroxymethyl) aminomethane and acrylic acid under the irradiation of an ultraviolet lamp. Through electrostatic interaction between carboxyl of the copolymer and amino of the tobramycin, the tobramycin is incorporated into a hydrogel network, so that the mechanical strength is increased, and drug release is controlled. Chitosan exists as another cross-linking agent, so that the mechanical strength of the hydrogel can be adjusted. The hydrogel has an easy-to-synthesize process and sufficient mechanical strength and adhesion, and has the potential of providing a promising and practical combined treatment method for effectively treating chronic infectious diabetes wounds.

This application discloses an odor-removing product comprising an absorbent with an adsorption surface; a neutralizing agent comprising an acidic odor remover and an alkaline odor remover, each fixedly disposed on the adsorption surface; the acidic odor remover neutralizes alkaline odor components, and the alkaline odor remover neutralizes acidic odor components; and a biological inhibitor disposed on the adsorption surface to inhibit microbial growth. Therefore, it can neutralize and remove odors from both alkaline and acidic odor components, thereby achieving deodorization, and also inhibits microbial growth based on the biological inhibitor to prevent bacterial proliferation, thus achieving both odor removal and antibacterial effects and improving the user experience.

The utility model discloses a wear-resistant antibacterial ceramic tile, which relates to the field of ceramic tiles, and comprises a bottom plate, the top of the bottom plate is connected with a wear-resistant mechanism, the wear-resistant mechanism further comprises antibacterial glaze, the antibacterial glaze is also connected to the upper surface of an activated carbon layer, and an aluminum oxide material and the antibacterial glaze are mixed to form the wear-resistant antibacterial ceramic tile. The upper surfaces of the antibacterial glaze and the aluminum oxide material are connected with a microporous DLC (Diamond Like Carbon) protective film. According to the wear-resistant antibacterial ceramic tile, silver ions can be diffused to the surface of the ceramic tile through the microporous buffer fluid and micropores of the microporous DLC protective film, the antibacterial effect of the ceramic tile can be achieved through the silver ions of the antibacterial glaze, the humidity of the ceramic tile can be balanced through the silicon dioxide aerogel, the activity of the silver ions is guaranteed, and the antibacterial effect is improved in a disguised mode; in addition, impact force borne by the silicon dioxide aerogel and the honeycomb blocks can be transmitted to the microporous buffer fluid, the hardness of the microporous buffer fluid can be increased after the microporous buffer fluid is subjected to high-speed impact through the characteristics of an object, and protection on the ceramic tile is greatly improved.

The utility model relates to the technical field of draw-bar boxes, in particular to a durable composite antibacterial draw-bar box, which comprises a box body and a box seat, the lower end of the box body is fixedly connected with the box seat, an antibacterial mechanism is arranged on the inner wall of the box seat, the antibacterial mechanism comprises a clamping block, the lower end of the clamping block is fixedly connected with the box seat, and the clamping block is fixedly connected with the box seat. The inner wall of the clamping block is fixedly connected with a mounting pipe, the inner wall of the mounting pipe is fixedly connected with a limiting ring, the outer wall of the limiting ring abuts against a mounting cylinder, an antibacterial core is mounted on the inner wall of the mounting cylinder, the end of the mounting pipe is in threaded connection with a cover, and a circulating pipe is mounted on the outer wall of the mounting pipe. The two sets of fans rotate on the fans on the connecting frame, so that air inside and outside the box body enters the circulating pipe and enters the mounting pipe and the mounting cylinder, an antibacterial core inside the mounting cylinder adsorbs bacteria, mites, moisture and the like in the inside and outside air, and the effects of cleaning, drying and resisting bacteria of the box body are achieved.

The application relates to the technical field of sterilization and disinfection, in particular to a long-acting antibacterial composition for hard surfaces and application and use method thereof. The antibacterial composition is composed of a polymer precursor and a polymer base molecule in a molar ratio of 1:(100-200); the polymer precursor is obtained by modifying one or more of amino groups, hydroxyl groups, double bonds, siloxanes and isocyanate groups on the basis of a photodynamic molecule; the photodynamic organic molecule is one or more of porphyrin, metal porphyrin, dihydrogenophorin, phthalocyanine, fluorinated boron dipyrrin, pyrrolopyrrole diketone, cyanine dye, coumarin, benzophenone, isoazoline, riboflavin and ring metal complex and derivatives thereof. The application mainly realizes the long-acting antibacterial effect by depositing the photodynamic functional organic molecule on the hard surface and forming a stable coating structure, and the coating structure has very strong hardness.

The invention relates to the technical field of hand sanitizers, in particular to a no-wash hand sanitizer and a preparation method thereof. The no-wash hand sanitizer is prepared from the following components in percentage by mass: 0.5 to 1 percent of modified soybean peptide, 0.8 to 1.2 percent of artemisia japonica polysaccharide, 1 to 3 percent of glycerol, 0.3 to 0.5 percent of carbomer, 0.05 to 0.15 percent of triethanolamine, 0.1 to 0.5 percent of vitamin E, 0.02 to 0.05 percent of rose essence and the balance of distilled water, the structural formula of the modified soybean peptide is as follows: # imgabs0. The no-wash hand sanitizer provided by the invention is excellent in sterilization effect, long in action time, mild, skin-friendly and non-irritant.

The utility model discloses an antibacterial flame-retardant non-woven fabric which comprises a polyester fiber skeleton base layer, an isolation breathable layer, an antibacterial layer and a flame-retardant layer, air holes are formed in the polyester fiber skeleton base layer; the isolation breathable layer is arranged on the top surface of the polyester fiber skeleton base layer; the antibacterial layer is arranged on the top surface of the isolation breathable layer; the flame-retardant layer is arranged on the top surface of the antibacterial layer. The antibacterial and flame-retardant fabric has good antibacterial and flame-retardant performance, and meanwhile better air permeability can be guaranteed.

The invention discloses a modified organosilicon polymer material and a preparation method thereof, and relates to the field of polymer materials. When the modified organic silicon high polymer material is prepared, silicon dioxide sequentially reacts with 3-aminopropyltrimethoxysilane, 3-formyl-4-methyl hydroxybenzoate and sodium hydroxide, and modified silicon dioxide is prepared; the preparation method comprises the following steps: sequentially reacting 4-vinyl phenylboronic acid with 3, 4-dihydroxy-1-butene and 3-sulfydryl-1-propylamine to prepare a self-repairing monomer; reacting a self-repairing monomer, 1, 3-bis (3-aminopropyl) tetramethyldisiloxane, 3-aminopropyl trimethylsilane, formaldehyde and glyoxal to prepare an organic silicon polymer, and uniformly mixing the organic silicon polymer with the modified silicon dioxide to prepare the modified organic silicon polymer material. The modified organic silicon polymer material prepared by the invention has antibacterial, wear-resistant, anti-aging, flame-retardant and self-repairing effects.

A method for producing a biodegradable fiber containing inorganic filler particles by a wet spinning method, said method comprising: dissolving a mixture, which is obtained by mixing inorganic filler particles and a biodegradable resin at a weight ratio of 50-80: 50-20, in a good solvent, and stirring the mixture to prepare a spinning solution; a spinning tube of a wet spinning device is filled with the spinning solution, and the spinning solution is pressed downwards from a discharge port of an incidence needle and is ejected into a collection container. In the collecting container, the upper layer and the lower layer are filled with a first poor solvent with the solubility parameter value having a small deviation degree relative to the good solvent and a second poor solvent with the specific gravity larger than that of the first poor solvent and the solubility parameter value having a large deviation degree relative to the good solvent. The spinning solution pressed out from the ejection opening of the injection needle is injected into the first poor solvent in the collection container in a fiber shape by means of self weight, and then is continuously injected into the second poor solvent filled with the first poor solvent. The fibrous spinning solution entering the second poor solvent is formed into continuous long fibers and floats and accumulates at the bottom of the collection container, thereby forming a cotton fiber shape.

The invention relates to the field of cold-chain logistics packaging, in particular to a fresh-keeping foam box for cold-chain turnover and a preparation method of the fresh-keeping foam box, and aims at solving the problems that an existing fresh-keeping foam box is limited in heat insulation performance and poor in antibacterial effect. According to the preparation method, polystyrene is used as a main raw material, then heat-insulating antibacterial particles are added into the polystyrene, the heat-insulating performance of the fresh-keeping foam box can be remarkably improved, the heat-insulating antibacterial particles have good adsorption performance and can adsorb moisture and peculiar smells in the foam box, meanwhile, the heat-insulating antibacterial particles have antibacterial and fresh-keeping effects, and the heat-insulating performance of the fresh-keeping foam box is improved. Growth of bacteria and mould can be inhibited, deterioration of articles is prevented, and the shelf life of the articles is prolonged; by using the fresh-keeping foam box, the temperature stability, sanitation and safety of goods in the transportation process are ensured, and the risk of cold chain breakage and the possibility of microbial contamination are reduced, so that the safety and reliability of cold-chain logistics are greatly improved, the food safety is ensured, and the requirements of modern cold-chain transportation are met.

The invention relates to the technical field of coatings, and discloses a stone coating with high cohesiveness and a preparation method thereof.Diallylamine, gamma-mercaptopropyltriethoxysilane, 1, 2-epoxy-5-hexene, (2-chloroethyl) benzene, 1, 6-hexamethylene diisocyanate tripolymer and the like are used as raw materials and subjected to a series of reactions, and the stone coating with high cohesiveness is prepared. And taking the modified polyurethane oligomer as matrix resin, adding an active diluent and the like into the matrix resin, and uniformly stirring to obtain the stone coating. The stone coating prepared by the preparation method disclosed by the invention contains silicon hydroxyl, the silicon hydroxyl can be combined with hydroxyl on the surface of a stone through hydrolytic condensation, the adhesive property is improved, and a urethane bond contained in the stone coating can react with the hydroxyl of the stone, so that the adhesive property of the coating and the stone is further enhanced. The stone coating prepared by the preparation method disclosed by the invention has relatively good adhesive property, antibacterial property and mechanical property.

This invention discloses a scale inhibitor, rust inhibitor, and microbial suppressant, comprising the following components by mass percentage: a mixture of benzotriazole and benzimidazole derivatives (10-12%); compound component A: sebacic acid (0.8-1.0%), citric acid (0.8-1.0%), and diisooctyl sebacic acid (1.2-1.5%); compound component B: propylene glycol (8-10%) and ethylene glycol (5-8%); compound component C: sodium citrate (2-2.5%), sodium silicate (1.5-2.0%), and sodium polyacrylate (1-1.5%); pH adjuster: triethanolamine (10-20%); and the balance being demineralized water. The beneficial effects of this invention are: the agent obtained by this invention has strong scale inhibition, good corrosion inhibition, good antibacterial effect, strong durability, simple preparation, wide applicability to water treatment, is environmentally friendly, has low pollution, does not use harmful substances such as phosphates and nitrites, has strong adaptability, good practicality, and long-lasting effect, effectively reducing the number of times reagents need to be added or the number of water changes required.

The invention discloses a preparation method of a composite leather fatliquor, and belongs to the field of chemical synthesis of leather fatliquor. The steps include: vegetable oil, trans-cinnamic acid and an organic solvent are mixed and dissolved to form a reaction solution, and the reaction solution is heated to 70°C~80°C and then an oil-soluble initiator is added for mixed reaction for 1h~2h to obtain a vegetable oil-based polymer; after the vegetable oil-based polymer, amphoteric surfactant and a copper ion-containing solution are mixed, an inorganic base is added to adjust the pH to 8~9 to catalyze chelation for 40min~80min to obtain a copper ion-plant oil-based polymer; copper ion-plant oil-based polymer is catalyzed by a vulcanizing agent to obtain a composite leather fatliquor. The present invention uses vegetable oil containing unsaturated carbon-carbon double bonds as a raw material, and uses trans-cinnamic acid of plant origin, environmentally friendly and fragrant as an odor improver to cover the smell of vegetable oil. After the two react, copper ions are chelated, and then the chelated copper ions are vulcanized and fixed, which solves the problem of easily producing unpleasant odors to greasy raw materials.

The present invention discloses a fusidic acid derivative and a preparation method and application thereof. The present invention derivatizes the 3-OH site of fusidic acid through a linker with a disulfide bond, introduces different terminal functional groups on the one hand, and adjusts the properties of the fusidic acid molecule, such as the introduction of an amino group or a carboxyl group can change the water solubility of the molecule under different pH conditions, and the polyethylene glycol structure can change the systemic circulation characteristics of the molecule, etc. At the same time, active functional groups such as alkynes, amino groups, and carboxyl groups provide sites for further modification, thereby modularly constructing more functional fusidic acid derivatives. The disulfide bond in the linker can effectively maintain the antibacterial activity of fusidic acid, and in the presence of a polypeptide adjuvant, effective killing of Gram-negative bacteria is achieved. The preparation method of the present invention is simple, and the product separation and purification is easy.

A method for preparing and applying a nano-removable coating that can isolate saliva contamination and improve the bonding strength of zirconia restorations. The method includes the following steps: (1) cleaning the substrate material; (2) preparing a tannic acid solution and a ferric chloride hexahydrate solution; (3) sequentially adding the ferric chloride hexahydrate solution and tannic acid solution to the cleaned substrate material, vortexing, adjusting the pH value, continuing vortexing, washing, and drying to obtain a nano-removable coating that can isolate saliva contamination and improve the bonding strength of zirconia restorations. The MPN coating provided by this invention can effectively isolate the interaction between proteins and the zirconia substrate material, overcoming saliva contamination caused during restoration trial. It can be pre-coated before trial and removed before clinical bonding. Furthermore, the bonding durability of zirconia restorations treated with this MPN coating is close to that of zirconia restorations treated with cleaning agents, and superior to zirconia restorations treated with Ivoclean cleaning agent.