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System for pre-operative assessment of post-hepatic resection complication risk of subject

A technology of subjects and complications, applied in the field of preoperative risk assessment, to achieve good reliability results

Pending Publication Date: 2022-04-12
SECOND MEDICAL CENT OF CHINESE PLA GENERAL HOSPITAL
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, there is still a lack of a complete system in the field of liver surgery complications to evaluate through preoperative factor prediction

Method used

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  • System for pre-operative assessment of post-hepatic resection complication risk of subject
  • System for pre-operative assessment of post-hepatic resection complication risk of subject
  • System for pre-operative assessment of post-hepatic resection complication risk of subject

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0169] Embodiment 1 Materials and methods

[0170] 1.1 Case selection

[0171] Establish personal medical information files for patients undergoing liver surgery during the perioperative period. Inclusion criteria for cases: (1) perioperative patients; (2) complete medical records; (3) non-recent secondary surgery. A total of 1732 cases were collected from January 1986 to December 2020.

[0172] Among them, medical records include preoperative clinical medical records, histopathological examination data and postoperative data; after admission, all patients were asked about medical history and physical examination in detail; routine preoperative clinical examinations included electrocardiogram, chest X-ray and blood routine , blood biochemistry, coagulation function and other laboratory tests; imaging examinations include ultrasound, CT and / or magnetic resonance, and use them as the basis for diagnosis; liver function assessment (Child-pugh) is performed on all patients; preope...

Embodiment 2

[0199] Example 2 Preliminary Model Result Evaluation

[0200] 2.1 Incidence of complications after liver surgery

[0201] A total of 419 cases of complications occurred, the total incidence of complications was 24.19%. Among them, 14 cases had fatal complications, accounting for 3.34% of the total number of complications, and the mortality rate was 0.81%.

[0202] 2.2 Screen preoperative clinical risk factors for postoperative complications

[0203] According to univariate correlation analysis, the preoperative clinical risk factors for complications after liver surgery were history of previous surgery (P=0.006), history of abdominal surgery other than liver surgery (P=0.021), total bilirubin (P<0.001), Medical diseases requiring drug treatment (P<0.001), Child-pugh grade (P<0.001), number of total liver segments to be resected (P=0.001), lesion nature (P=0.001), resection method (P<0.001), Whether the surgical margin was positive (P=0.022), whether there was organ invasion...

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Abstract

The invention provides a system for evaluating the risk of complications after hepatic resection of a subject before an operation, and the system comprises a data collection module which is used for obtaining the Child-pugh level of the subject, the condition that whether internal medicine diseases need to be treated by drugs exist, the number of liver segments to be resected, the condition that whether visceral organ invasion exists in the subject or not, and the preoperative hospitalization time of the subject; and the module is used for calculating the complication risk of the subject after the hepatic resection and is used for calculating the information acquired in the data acquisition module so as to calculate the complication risk probability (P) of the subject after the hepatic resection. The system has good reliability, the preoperative prediction of the occurrence rate of the liver surgical complications has good consistency with the actual situation, and the system can be used for evaluating the occurrence risk of the liver surgical complications before the operation.

Description

technical field [0001] The present invention relates to the technical field of risk assessment before surgery, in particular to a system for assessing the risk of complications after hepatectomy of a subject before surgery. Background technique [0002] Hepatectomy has always affected the prognosis of surgery due to its complexity, high complication rate and mortality rate, but in recent years, to optimize the selection of surgical patients, anesthesia and perioperative management, especially the establishment of hepatobiliary surgery as a specialty, The safety of liver resection has been significantly improved. In the past half century, the safety of liver resection has always been the first priority in liver surgery. Liver surgery has developed rapidly, and liver resection has changed from a risky operation to a relatively safe operation. However, liver surgery still has a high incidence of complications and mortality, and appropriate preoperative preventive strategies m...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G16H50/30
Inventor 徐立宁杨波徐盈盈黎桂平
Owner SECOND MEDICAL CENT OF CHINESE PLA GENERAL HOSPITAL
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