368 results about "Cerebral hemorrhages" patented technology

The invention discloses a traditional Chinese medicine for treating hypertension, which is prepared by the following raw materials by weight ratio: 10-30 of codonopsis, 20-60 of membranous milkvetch root, 20-60 of dried rehmannia root, 20-60 of figwort root, 15-40 of dwarf lilyturf tuber, 15-30 of common anemarrhena rhizome, 15-40 of white paeony root, 10-30 of Chinese angelica, 20-50 of common yam rhizome, 10-30 of baical skullcap root, 10-30 of cortex phellodendri, 10-30 of gardenia, 10-30 of lightyellow sophora root, 20-60 of cassia seed, 20-60 of ruddle, 10-50 of mirabilite, 10-20 of rhubarb, 15-50 of salvia miltiorrhiza, 10-30 of cortex moutan, 10-20 of common burreed rhizome, 10-20 of rhizoma zedoariae, 10-40 of swordlike atractylodes rhizome, 20-40 of largehead atractylodes rhizome,20-50 of Indian buead, 15-40 of oriental waterplantain rhizome, 15-40 of snakegourd fruit, 10-30 of pinellia tuber, 15-40 of malaytea scurfpea fruit, 15-60 of common macrocarpium fruit, 10-20 of medcinal evodia fruit, 5-20 of cassia bark, 20-60 of barbary wolfberry fruit and 15-40 of desertliving cistanche. The traditional Chinese medicine improves the systemic symptoms by adjusting yin, yang, qiand blood of a human body, thereby achieving the effect of reducing the blood pressure and the significant efficacy; and the traditional Chinese medicine also has good efficacy for other related diseases caused by the hypertension and can prevent relevant complications of cerebral hemorrhage, stroke, coronary heart disease, high blood lipids, arteriosclerosis and the like, and improve the qualityof life of a patient.

The present invention is one kind of Chinese medicine composition for treating cerebral hemorrhage and is preparation process. The Chinese medicine composition consists of effective components from motherwort, giant knotweed, leech, gentian, and buffalo horn or rhinoceros horn; and may be prepared into medicine powder, tincture, capsule, tablet, micro pill and other forms. The Chinese medicine composition has the function of promoting blood circulation to disperse blood clots, and can alleviate hemorrhagic apoplexy cerebral edema, promote the absorption of hematoma and disease focus repair, improve the ischemic and anoxic state of nerve tissue around hematoma, protect damaged brain cell and promote restoring of the nerve function.

The invention discloses a patient transfer device capable of serving as a sickbed. The patient transfer device comprises a bearing unit, a lifting unit and a bracket unit, wherein the bearing unit comprises two vertical supports which are fixedly arranged and are vertically symmetric, and a horizontal transverse rod which is fixedly connected to the top ends of the vertical supports; the lifting unit comprises a lifting group and a translation group; the lifting group is such configured that a fixed pulley is connected to each of two ends of a lifting transverse rod which is horizontally arranged by virtue of a lifting rope, and the fixed pulleys are fixedly arranged on the horizontal transverse rod; the translation group comprises a translation sliding wheel which is arranged on the lifting transverse rod, and the translation sliding wheel is capable of sliding in a mode of translation along the lifting transverse rod; and the bracket unit, which is horizontally arranged, is connected to the lower end of the translation sliding wheel. The patient transfer device disclosed by the invention is applicable to patients who cannot be moved randomly due to fracture, spinal cord injury, cerebral hemorrhage, craniocerebral trauma and the like; the patient transfer device, after being used for transferring patients during and after operations, can serve as the sickbed; the patient transfer device is simple to operate; and the patient transfer device is capable of avoiding secondary injury to the patients and guaranteeing the comfort of the patients during moving to the greatest extent.

The invention provides a method for calculating intracerebral hemorrhage amount based on depth learning, which comprises the following steps: S1, obtaining CT image data of intracerebral hemorrhage and marking; S2, designing a segmentation model of an intracerebral hemorrhage region based on depth learning, and training the segmentation model by using the marked intracerebral hemorrhage CT image data; S3, inputting the tested CT image data of cerebral hemorrhage into the trained segmentation model to obtain the segmentation result; S4, calculating the volume of cerebral hemorrhage according tothe obtained segmentation result; S5: generating a structured report containing the location and volume of intracerebral hemorrhage. The invention can accurately and quickly calculate the amount of cerebral hemorrhage, and provides important decision information for clinical intervention.

The invention discloses a cordyceps and maca tablet. The cordyceps and maca tablet consists of maca roots, cordyceps militaris powder, corn starch, sorbitol and silicon dioxide. A method of preparing the cordyceps and maca tablet comprises the steps of grinding and mixing the maca roots, adding a wetting agent, screening and pelletizing, drying, carrying out secondary screening, total blending, tabletting, split charging, packaging, carrying out quality testing, and warehousing. According to the cordyceps and maca tablet provided by the invention, the cordyceps militaris and the maca are organically combined to enable the effects of the cordyceps militaris and the maca to be more prominent, therefore the effects of relieving fatigue, improving sleeping, resisting against cancer, enhancing the sexual capacity, alleviating cerebral thrombosis, cerebral hemorrhage and the like can be improved greatly; furthermore, the physical health problems of the aged can be effectively alleviated, and the treatment effect of the common cardiovascular and cerebrovascular diseases of the aged can be promoted.

The invention discloses a non-contracting magnetic induction type detecting system of cerebral hemorrhage. The non-contracting magnetic induction type detecting system of the cerebral hemorrhage comprises a signal generator, a helmholtz upper coil, a helmholtz lower coil, a left cerebral hemisphere detecting coil, a right cerebral hemisphere detecting coil, a first data collecting card, a second data collecting card, a tee joint and a phase discriminator main machine, wherein the helmholtz upper coil and the helmholtz lower coil are correspondingly arranged in parallel, the space between the helmholtz upper coil and the helmholtz lower coil is a detecting space of the head, the distance between the helmholtz upper coil and the helmholtz lower coil is equal to the radius of a coil, the left cerebral hemisphere detecting coil and a right cerebral hemisphere detecting coil are arranged in the detecting space of the head in a movable mode and the positions of the left cerebral hemisphere detecting coil and the right cerebral hemisphere detecting coil are symmetrical relative to the sagittal suture of the head. The non-contracting magnetic induction type detecting system of the cerebral hemorrhage is high in detection sensitivity of early-stage hemorrhage, accurate in location, deep in detection depth, strong in antijamming capability, in a non-contracting magnetic induction type, and beneficial to bedside intensive care.

The invention discloses a use of 4,7-dihydrotetrazyl[1,5-alpha]pyrimidine compound and its derivatives in preparation of a drug for prevention or treatment on cerebral hemorrhage. Through a self-created computer-assisted drug molecule design program and virtual screening, it is shown that the 4,7-dihydrotetrazyl[1,5-alpha]pyrimidine compound and its derivatives have a ROCK1 protein inhibitory activity and can be used for treating cerebral hemorrhage. Through further biological activity detection of the screened 4,7-dihydrotetrazyl[1,5-alpha]pyrimidine compound, it is shown that the screened 4,7-dihydrotetrazyl[1,5-alpha]pyrimidine compound has an obvious ROCK1 protein inhibitory activity and has good prevention and treatment effects in an atorvastatin-induced zebra fish cerebral hemorrhage model.

A medicine compound Brazilian haematein prime and a preparation method and function thereof relate to the preparation method of a medicine compound that is separated from lignum sappan heartwood. Aqueous alkaline solution extraction is adopted in the method, and no organic solvent is involved, therefore, the extraction cost is low and the operation is safe. Experiments with animals also prove that the produced Brazilian haematein prime is suitable for medicine preparation or curing diseases that are caused by blood pressure elevation in human body, such as various high blood pressures, arterial sclerosis of porridge type, coronary heart disease, cerebral thrombosis and cerebral hemorrhage, etc.

The invention provides a walking correction training instrument, a manufacturing method and a walking correction training method. A trunk positioning regulating platform is installed at the upper end of a main supporting frame, a chest correction assembly, a belly correction assembly and a walking console bracket are installed on one side of the trunk positioning regulating platform, a hip correction assembly, a back correction assembly and a master controller are installed on the other side of the trunk positioning regulating platform, and a space for human body in-position correction training is formed. The walking correction training instrument is reasonable in design, compact in structure, small in occupied space, simple in operation, easy to master, convenient to install and maintain, significant in correction training effect, and reliable in safety in training of a patient, the body of the patient in training is not injured, the chest, belly, hips, back and ankles in dynamic training are reasonably limited in a normal moving range, the patient can be in the optimum training state all the time in a training process, rehabilitation efficacy for common brain paralysis patients, trauma sequela patients, stroke sequela patients, patients with limb muscle weakness reduction caused by cerebral hemorrhage, patients with physical handicaps and patients with bad walking postures are achieved, and the instrument is suitable for being used in hospitals, rehabilitation centers and families.

The present invention relates to compounds of formula (I) and their pharmaceutical compositions. In addition, the present invention relates to therapeutic methods for the treatment and/or prevention of Aβ-related pathologies such as Down's syndrome, β-amyloid angiopathy such as but not limited to cerebral amyloid angiopathy or hereditary cerebral hemorrhage, disorders associated with cognitive impairment such as but not limited to MCI (“mild cognitive impairment”), Alzheimer's disease, memory loss, attention deficit symptoms associated with Alzheimer's disease, neurodegeneration associated with diseases such as Alzheimer's disease or dementia including dementia of mixed vascular and degenerative origin, pre-senile dementia, senile dementia and dementia associated with Parkinson's disease, progressive supranuclear palsy or cortical basal degeneration.

The invention relates to a cerebral hemorrhage analysis method, computer equipment and a storage medium. The method comprises the following steps: acquiring a to-be-analyzed image comprising at leastone bleeding area; inputting the image into a convolutional neural network for feature extraction; obtaining a feature map of an image, inputting the feature map into a region-of-interest extraction network; obtaining a feature map of a detection box containing each bleeding area, inputting the feature map of the detection box containing each bleeding area into a classification network to obtain aclassification result of each bleeding area, and inputting the feature map of the detection box containing each bleeding area into a detection box regression network to obtain the position of each bleeding area. According to the cerebral hemorrhage analysis method, detection and classification of the images containing the multiple hemorrhage areas are achieved at the same time, and the applicability and classification accuracy of the cerebral hemorrhage analysis method are improved.

The invention discloses a kit for quantitatively detecting GFAP concentration in human serum by polystyrene microsphere, comprising a 96-hole filter plate, a standard product, a sample diluent, a polystyrene microsphere coupled with an anti-GFAP antibody on the surface, a microsphere storage solution, an enzyme compound, a substrate A, a substrate B, a 20*cleaning solution, an adhesive sticker strip and an operating manual. The kit provided by the invention changes the solid phase carrier made of traditional microporous plate into the polystyrene microsphere, generates the antigen antibody reaction in the liquid phase to keep a good bioactivity and a correct spatial configuration, and eliminates the effect on the antigen antibody reaction by the surface tension and the steric hindrance ofthe traditional reaction mode, and effectively shortens the reaction time and the rinsing times, besides, the invention has the characteristics of simple operation, high sensitivity, good specificityand low cost and has important clinical significance for the diagnosis of the acute cerebral hemorrhage early disease degree.

The invention discloses a traditional Chinese medicine for treating cardiovascular and cerebrovascular diseases, which is mainly prepared from the following components in parts by weight: 20-50 parts of leech, 20-30 parts of earthworm, 25-40 parts of chicken's gizzard-membrane, 30-40 parts of rhizoma ligustici wallichii, 30-40 parts of radix salviae miltiorrhizae, 20-30 parts of radix notoginseng, 15-30 parts of safflower, 15-30 parts of Japanese sweetflag, 10-20 parts of TurmericRoot-tuber, 20-30 parts of senega and 10-20 parts of Chinese Ligusticum Rhizome. The traditional Chinese medicine aims at the cardiovascular and cerebrovascular diseases, is mainly used for treating coronary heart diseases, myocardial infarction, cerebral thrombus, cerebral infarction, hemiplegia, aphasia and apoplexy sequelae caused by the stasis of the veins of the heart and the brain and arteriosclerosis and can also relieve an adverse reaction occurring in the recovery period of cerebral hemorrhage. The clinical application of many years proves that the cure rate of the traditional Chinese medicine for treating the cardiovascular and cerebrovascular diseases reaches 63%, the total effective rate reaches 95%, and the traditional Chinese medicine has obvious effect and better popularization and application prospect.

The invention relates to a Chinese traditional medicinal combination, in particular to a Chinese traditional medicine used for cardiovascular and cerebrovascular diseases, namely Heart and Brain Shukang Gelatine Capsule. The Chinese traditional medicine is prepared from the following raw materials by weight part: 18 to 22 parts of radix salviae miltiorrhizae, 4 to 7 parts of draconis sanguis, 3 to 6 parts of scorpion, 3 to 6 parts of centipede, 16 to 22 parts of gastrodia tuber, 8 to 12 parts of leech, 8 to 12 parts of earth worm, 18 to 25 parts of hemlock parsley, and 8 to 14 parts of licorice. The Chinese traditional medicinal combination is applicable for curing hemiplegia and sequelae caused by hypertensive, hyperlipemia, arteriosclerosis and deficient blood supply to hearts and brains, coronary heart diseases, diabetes, cerebralthrombosis, cerebral infarction, encephalatrophy, cerebral hemorrhage and cerebral apoplexy, such as hemiplegia, slurred speech, numb limbs, dottiness and so on. The invention belongs to a pure Chinese traditional preparation without chemicals. The Chinese traditional medicine is innoxious and unharmful to human bodies with short cure period, and takes effect quickly and is administrated conveniently.

The invention discloses compound nanoemulsion oral liquid for reducing the blood fat. The particle size of the oral liquid is 1nm-100nm. The compound nanoemulsion oral liquid comprises the following components in percentage by weight: 2%-10% of EPA deep-sea fish oil, 0.1%-4% of carboxymethyl chitosan, 1%-3% of taurine, 0.1%-3% of apricot kernel oil, 0.1%-3% of perilla oil, 0.1%-1% of natural vitamin E, 30%-60% of surfactant, 1%-10% of cosurfactant, 1-6% of oil phase and the balance of deionized water, and the sum of the mass percents of all the components is 100%. The compound nanoemulsion oral liquid can reduce the total cholesterol of the blood, the low-density lipoprotein, the triglyceride and the absorption of lipid simultaneously, has an obvious effect for reducing the blood fat and plays a positive role in preventing the cardiovascular diseases such as cerebral thrombosis, cerebral hemorrhage and high blood pressure and the like.

The invention discloses a traditional Chinese medicine containing pseudo-ginseng powder and a preparation method thereof. The traditional Chinese medicine comprises, by mass, 60-100 parts of pseudo-ginseng powder, 20-30 parts of red sage root, 10-20 parts of licorice, 30-40 parts of radix rehmanniae, 15-25 parts of root of kudzu vine, 40-50 parts of radix astragali, 20-30 parts of bighead atractylodes rhizome, 60-80 parts of dextrin and 5-7 parts of powdered steatile. The traditional Chinese medicine utilizes pseudo-ginseng powder, red sage root and licorice as raw materials, does not contain hormones and antibiotics in Western medicines, and does not produce drug resistance. Natural plants adopted by the preparation method has no obvious toxic or side effects in research, have high safety, can be absorbed easily, can produce effects fast and are convenient for use. The traditional Chinese medicine can treat inner and outer hemorrhagic diseases such as a bleeding wound, blood stasis, gastrorrhagia and hematuria, has effects of expanding blood vessel, dissolving thrombus, improving microcirculation, preventing and treating cardiovascular and cerebrovascular diseases such as hyperlipidemia, cholesterol increasing, coronary heart disease, stenocardia and cerebral hemorrhage sequel, treating liver diseases such as fatty liver and liver fibrosis, and treating physical deficiency caused by hemorrhage, delivery and aeipathia, has a low cost and simple processes, and can be widely used.

The invention relates to a huperzine A preparation for treating schizophrenia and nervous function damage and a preparation method thereof. The preparation method comprises the following steps: using a solvent dispersing method and a solid-liquid phase dispersing and melting method to properly dissolve huperzine A by solvent, preparing stable huperzine A hydrochloride solution, spraying the huperzine A hydrochloride solution in an auxiliary material by dispersion, or preparing solid dispersoid mixture with uniform phase dispersion, crushing, mixing and stirring uniformly, directly adding a lubricating agent for tabletting, also being capable of adding a binding agent, granulating, drying, adding the lubricating agent, and tabletting. The phase-dispersing mixture of huperzine A also can be added with the lubricating agent with proper amount for mixing, and then filled into a capsule. The preparation is used for treating the symptoms of all the periods of schizophrenia, and has the advantages of having the effects of protecting oxidative stress toxicity of nerve cells generated by resisting Beta amyloid peptide and inducing cell apoptosis, promoting the growth of nerve growth factor, being effective for treating inflammation in cerebral hemorrhage and inflammation of cerebral ischemic injury, having long action time of drugs, being convenient to application of oral administration/containing administration and the like. The invention has high content of huperzine A preparation, stable preparation quality and good bioavailability and can improve the medication compliance of patients with schizophrenia and senile dementia.

The invention discloses application of (E)-2-(3,5-dimethoxybenzylidene)-cyclopentanone in preparing a medicine for treating cerebrovascular diseases. The related research indicates that the compound has an obvious cranial nerve protection effect, obviously reduces the focal cerebral ischemia rat cerebral infarction volume and remarkably improves the neurologic symptom. The (E)-2-(3,5-dimethoxybenzylidene)-cyclopentanone is used for preventing or treating the diseases such as ischemic brain injury, cerebral hemorrhage, cerebral thrombosis, cerebral embolism, cerebral infarction, cerebral apoplexy, lacunar infarction, transient ischemic attack, cerebral arteriosclerosis, diabetic cerebrovascular complications and the like.

The invention discloses a contralateral-hemisphere-counteraction-based method for non-contact magnetic induction cerebral hemorrhage detection. Firstly, a tested head is placed below a first detection coil and a second detection coil which are the same, and an exciting coil is placed above the two detection coils; a signal generator is connected to the exciting coil and the input end of a three-way adapter; the first detection coil and the second detection coil are connected to an input channel of a first data acquisition card and an input channel of a second data acquisition card; a phase difference measurement procedure in a computer respectively and simultaneously calculates the phase difference between signals of the two input channels of the first data acquisition card and the second data acquisition card; the phase difference is obtained by subtracting phase difference data of one data acquisition card from phase difference data of the other data acquisition card, and the severity and the development and changes of cerebral hemorrhage can be judged according to variations of the phase difference. According to the contralateral-hemisphere-counteraction-based method for non-contact magnetic induction cerebral hemorrhage detection, the phase difference data produced by the left hemisphere and the right hemisphere are measured respectively, then counteraction is carried out on the phase difference data, and detection sensitivity and anti-jamming capability are improved greatly.

A thrombolytic and lipid-lowering pill is a drug applicable to treating headaches, insomnia, dizziness, cardio-cerebral insufficiency, arrhythmia, atrial fibrillation, myocardial infarction, premature beat, cerebrovascular arteriosclerosis, cerebral thrombosis, cerebral infarction, cerebral hemorrhage sequela, acragnosis, tinnitus, deafness, facioplegia, facial paralysis, aphasia from apoplexy and apoplectic hemiplegia sequela. The pill is prepared by the following raw materials: bupleurum, the root of kudzu vine, the root of red-rooted salvia, astragalus, cassia twig, the root bark of the peony tree, white paeony root, red paeony root, angelica, the rhizome of chuanxiong (fried), earthworm, cassia occidentalis, whole worm, muscardine cadaver, centipede, benzoin, rhizoma gastrodiae, triplostegia glandulifora, the root of bidentate achyranthis, pangolin scales, notopterygium root, giant typhonium rhizome, radix angelicae pubescentis, long-noded pit viper, zaocys dhumnade, asarum, Fushen, honeysuckle flower, cape jasmine fruit and liquorice. The pill has good treatment effects and fast effects, addresses both the symptoms and root causes and is convenient to take. After years of clinical testing, the pill effectively relieves the pains of many patients and is well thought of by mass patients.

The invention relates to a medicament for treating cardiac, cerebral and vascular diseases. A preparation method comprises the following steps of: uniformly mixing 160 to 200 parts of sanguisuga, 100 to 150 parts of dragon's blood, 120 to 160 parts of radix pseudo-ginseng, 1 to 2 parts of artificial musk, 100 to 150 parts of sandalwood, 80 to 120 parts of frankincense, 80 to 120 parts of myrrh, 100 to 150 parts of Chinese angelica, 100 to 150 parts of szechuan lovage rhizome, 120 to 160 parts of root of red-rooted salvia and 100 to 150 parts of radix curcumae, grinding the mixture into fine powder capable of passing a sieve of 80 to 100 meshes, sterilizing, and encapsulating to prepare the medicament. The medicament has the effects of nourishing Qi and activating blood, removing stasis and reducing turbidity, warming Yang and transfering Qi, moving Qi and dissipating binds, and refreshing brain and opening orifices, and mainly treats coronary heart disease, myocardial infarction, angina, hyperlipemia, high blood viscosity syndrome, cerebral thrombosis, cerebral infarction, and hemiplegia, facial paralysis, language disadvantage, limb numbness, weakness, ballism, encephalatrophy, senile dementia caused by cerebral hemorrhage sequela and other symptoms; Clinical application of 2,580 cases of patients with cardiac, cerebral and vascular diseases proves that the cure rate of the medicament is 78 percent; and the total effective rate of the medicament is 98.8 percent.

The present invention relates to an oral liquor for curing cerebral hemorrhage and its preparation method by using leech as main raw material. The oral liquor is made up by using the Chinese medicinal materials of leech, notoginseng and rhubarb according to the ratio of 6:1:2.