57 results about "Arterial aneurysms" patented technology

The invention discloses a method for preparing brain tissue and vascular entity composite model based on MRI (magnetic resonance imaging) and CTA (CT angiography). The method includes: 1), acquiring image data of head and neck skull, brain tissue, vessel and arterial aneurysm; 2), leading acquired MRI and CTA original image data into three-dimensional reconstruction software, structuring a 3D composite virtual model containing the skull, brain tissue, vessel and arterial aneurysm and outputting to a 3D printer for 3D model printing in a format that the 3D printer can print to acquire the three-dimensional entity composite model containing the skull, brain tissue, vessel and arterial aneurysm. The model is quite high in simulation degree, so that doctors can perform preoperative discussionof surgical planning, preoperative risk assessment and design of operative route or even simulate operation in combination with the model; the brain tissue model is of fluid silicone brain tissue thatcan be pulled apart and can be pulled apart as in actual operation, so that the doctors are more confident, and operation risks are lowered.

The invention discloses an intravascular stent with complex functions. The intravascular stent comprises a stent main body which is mesh-shaped and can be released from and retracted to a feeding catheter, wherein a near end of the stent main body is openly conical, the middle part of the stent main body is circular tube-shaped, and a far end of the stent main body has a closed structure; and the stent main body has a mesh shape which is woven by single wires or a plurality of wires or is engraved by a laser engraving machine. The stent which is taken as an acute thrombus removal system can quickly and efficiently take out thrombi, and can also capture small thrombi which flow toward the far end so as to avoid secondary stroke caused by the thrombus blockage of the far end; the stent which is taken as a temporary stent expands intracranial blood vessels or narrow and blocked blood vessels on other parts of human bodies, plays the effects of dredging and reconstructing blood flow, and can capture small thrombi or emboli; and the stent which is taken as a long-term implanted stent performs adjuvant therapy on arterial aneurysms of furcations, and fills in a market gap. If the position of the stent is not satisfactory, the entire stent can be retracted to the feeding catheter, and is released again. The maneuverability of the stent is high, so the operation difficulty is reduced, and the surgical success rate is greatly improved.

The invention provides a simulation method and device for intracranial aneurysm treatment. The method comprises the following steps: establishing a three-dimensional structure of a spring ring and placing the spring ring into an arterial aneurysm: packaging the spring ring into a simulated catheter in a simulated calculation manner and then releasing the spring ring into the arterial aneurysm; establishing a three-dimensional structure of a stent and placing the stent into an arterial aneurysm carrying blood vessel: compressing and placing the stent into a micro catheter in a simulated calculation manner, then bending the stent and the micro catheter, and releasing the stent into the arterial aneurysm carrying blood vessel; establishing a structure of the spring ring, and when the spring ring is placed in the arterial aneurysm, simulating the spring ring into a three-dimensional Euler-Bernoulli beam; establishing a three-dimensional structure of the stent, and when the stent is placed in the arterial aneurysm carrying blood vessel, simulating the stent into a three-dimensional shell unit; when the stent is released into the arterial aneurysm carrying blood vessel, bending the stent and the micro catheter along the central line of the arterial aneurysm carrying blood vessel. The device is used for implementing the simulation method. According to the simulation method and the device, the simulation calculation efficiency can be improved, and the calculation time is shortened.

The invention relates to a circular bilateral Gabor filtering and local gradient analysis based automatic detection method for a microaneurysm in a color eye fundus image. The method comprises: firstly, preprocessing a green channel of the color eye fundus image; secondly, extracting candidates by adopting circular bilateral filtering and performing threshold segmentation to remove main blood vessels; and finally, calculating a local gradient direction histogram, removing tiny blood vessels according to the gradient direction anisotropy of the microaneurysm, calculating local contrast and roundness, and filtering out noises and bleeding points, thereby realizing the automatic detection of the microaneurysm. According to the method, the gray-level and structure information of the microaneurysm and the local gray-level difference of the tiny blood vessels are utilized, so that the influences of non-uniform illumination, low contrast and the tiny blood vessels can be overcome; the method not only can accurately detect large-sized, high-contrast and single-background microaneurysms but also has a very good detection effect on small-sized and low-contrast microaneurysms with complicated backgrounds close to blood vessels, yellow spots and the like; and finally the automatic detection of the microaneurysm is realized.

The invention relates to a rapid capture device of a three-dimensional structure. Compared with an existing two-dimensional plane loop capture device, the three-dimensional rapid capture device has the advantages that due to the fact that the three-dimensional structural design is adopted, the space where capture can be conducted is greatly expanded and a leap from the two-dimensional plane to the three-dimensional structure is achieved. The three-dimensional rapid capture device comprises a handle, a capture rod and a capture sleeve. One end of the capture rod is connected with the handle and the other end of the capture rod is connected with the capture sleeve. The capture sleeve comprises at least three spiral capture wires, wherein the two ends of each capture wire are connected with the two ends of another capture wire respectively. When the capture sleeve is used, the capture wires face one another and are expanded in a spiral mode, so that a three-dimensional network space is formed. The three-dimensional rapid capture device is applied to a congenital heart disease cardiac transcatheter closure operation and other transcatheter interventional therapy (such as an arterial aneurysm operation) and is used for rapidly capturing guidewires to establish a conveying track.

The invention relates to a multi-channel membrane-coated intravascular stent and a preparation method thereof. A multi-channel intravascular stent is coated with a membrane and comprises a stent body, wherein the surface of the stent body is coated with a polytetrafluoroethylene membrane; the polytetrafluoroethylene membrane is prepared by electrospinning the surface of the stent body with a polytetrafluoroethylene solution; the polytetrafluoroethylene solution comprises polytetrafluoroethylene and perfluor-paraffin; and the concentration of the polytetrafluoroethylene is 1-30g/ml. Compared with the prior art, the polytetrafluoroethylene layer clads the surface of the stent body; the performance of the coating is similar to that of expanded polytetrafluoroethylene; and the coating can be processed into various shapes such as barrels, circles and curved surfaces, thus the multi-channel intravascular stent is suitable for complicated arterial aneurysm treatment; and the achievement ratio of an operation is improved.

The present invention relates to an endoprosthesis composed of (a) two complementary bodies, body “A” and (b) a body “B”, with the said bodies being formed by proximal, intermediate and distal regions and comprising a self-expanding structure of resistant and flexible material and a graft wherein the said bodies “A” and “B” have a bifurcation for use where a main vessel bifurcates into at least two secondary branches, such as in the case of the treatment of aneurysms in the abdominal aorta.

The invention further includes a delivery system for the endoprosthesis of the present invention, as well as its use in the treatment of aneurysms.

The invention discloses an intravascular multilayer bare stent system, and relates to the technical field of medical equipment. According to the technical points, a support body is composed of a firstframework and a second framework, and the first framework and the second framework are of a cylindrical net structure formed by weaving framework lines made of memory alloy or biodegradable polymer materials, overlapped with each other and opposite in spiral rotation direction. Rotary connecting rings are arranged at the upper sections, the middle sections and the lower sections of the first framework and the second framework; metal wires are connected to the inner wall of the rotary connecting ring; a hole-sealing strip-shaped film is connected to the side wall of the metal wire. The mesh sealing of the multilayer bare stent can be adjusted, so that the aneurysm cavity and the interlayer are isolated from normal blood flow, normal blood flow is prevented from leaking into the aneurysm cavity and the interlayer, blood flow in the aneurysm cavity and the interlayer is restrained, blood clots or thrombi are promoted to be formed in the aneurysm cavity and the interlayer to atrophy the aneurysm, the pressure in the aneurysm cavity is reduced, the potential risk that the aneurysm is increased and ruptured is reduced, and stable and guaranteed treatment purpose is achieved.

A hydrogel based occlusion system, a method for occluding vessels, appendages or aneurysms, and a method for hydrogel synthesis are disclosed. The hydrogel based occlusion system includes a hydrogel having a shrunken and a swollen state and a delivery tool configured to deliver the hydrogel to a target occlusion location. The hydrogel is configured to permanently occlude the target occlusion location in the swollen state. The hydrogel may be an electro-activated hydrogel (EAH) which could be electro-activated with a delivery system to control the degree of swelling/shrinking.

The invention discloses a partial covering film vascular stent. The partial covering film vascular stent comprises a bare stent body and a covering film. The bare stent body is partially covered with the covering film, wherein the covering film accounts for 1/2 to 3/4 of the circumferential surface area the bare stent body. At least one first X-ray-impermeable marking point is arranged on the middle horizontal line of the covering film. At least two second X-ray-impermeable marking points are arranged on the left edge or the right edge or the upper edge or the lower edge of the covering film. According to the partial covering film vascular stent, the covering film is arranged on the bare stent body in a longitudinally covering mode, an X-ray-impermeable marking point is arranged in the middle of the covering film on the bare stent body, two X-ray-impermeable marking points are arranged on the edge of the covering film, so that the position of releasing the stent is determined, and it is guaranteed that an arterial aneurysm is covered with the covering film side after the stent is released and a branch blood vessel is not covered with the bare stent body.

The embodiment of the invention discloses a thrombus attribute information obtaining method, device and equipment and a storage medium. The method comprises the steps: constructing an original supportmodel and an original arterial aneurysm model according to a support parameter of a dense net support and a target three-dimensional image; determining a target arterial aneurysm model according to the original support model and the original arterial aneurysm model after the dense net support is placed; performing the computational fluid mechanics simulation based on the target arterial aneurysmmodel according to a preset thrombus forming process, and obtaining a target simulation result; and determining the thrombus attribute information corresponding to the dense net support and the targetthree-dimensional image according to the target simulation result. Through the above technical scheme of the invention, the method achieves the obtaining of the thrombus attribute information after arterial aneurysms of patients are placed on different dense net supports before operation, thereby providing more precise data support for the clinical treatment of the intracranial aneurysm.

The invention relates to an intracranial aneurysm blood flow guide support. The guide support comprises a main body part and an encryption part, wherein the main body part is of a cylindrical structure which is formed by weaving stent wires manually or by a weaving machine and is provided with an overlapping part through curling and shaping, the encryption part is arranged at the overlapping partfor mesh encryption, and the overlapping part and the encryption part cover an aneurysm opening. By means of the structural design, normal blood circulation of nearby side branch blood vessels is keptwhile blood flowing into the aneurysm is blocked, and in addition, due to the fact that axial stretching and retracting are reduced when the stent is pressed and held, the release difficulty is lowered.

The invention generally relates to co-axial stent and catheter systems and medical procedures utilizing these systems. The co-axial stent system is characterized by two-coaxial stents, including an outer resorbable stent and an inner metal stent used to effect deployment of the resorbable stent. The stents may use for treatment of unstable plaque and/or thrombus at the carotid bifurcation and particularly those that are not causing any significant stenosis. The stents may also be used for treatment of cerebral aneurysms. The invention further describes related, equipment, uses and kits for the treatment of unstable plaque and/or thrombus and/or aneurysms.

The invention relates to an embedded type intelligent controllable blood vessel locking device. The embedded type intelligent controllable blood vessel locking device comprises a shell, an actuator and a control module, wherein the shell accommodates the blood vessel and carries the actuator and the control module; the control module provides electric energy and a control signal for the actuator;the actuator comprises a fixed part, an electrical activity polymer material and a movable part, after electrifying, the electrical activity polymer material deforms and drives the movable part to move, the blood vessel accommodated in the shell is squeezed, so that the blood vessel is gradually locked. The embedded type intelligent controllable blood vessel locking device is designed aiming at the demand of treating intracranial aneurysm, basicranial tumor or other brain diseases, and the defects in the existing methods that lesion blood-supply internal carotid is blocked in advance before treatment. The embedded type intelligent controllable blood vessel locking device can be completely implanted in the body, wrap the blood vessel, and slowly lock the internal carotid in a controlled manner, so that the blood-supply brain tissue of internal carotid can obtain compensatory blood supply of other blood vessels, the dependence on the artery is eliminated, then the internal carotid is cutoff, so that cerebral infarction can not be caused, and conditions are created for disease treatment.

Aneurysms are classified and quantitatively analyzed based on medical image data acquired from a subject. In general, one or more algorithms are implemented to automatically classify, or otherwise diagnose, and measure aneurysms and their change over time. These algorithms make use of artificial intelligence and deep learning to develop quantitative analytics that can be consolidated into diagnostic reports.

The embodiment of the invention discloses a system and method for predicting the rupture potential of an aneurysm, electronic equipment and a medium, and the method for predicting the rupture potential of the aneurysm comprises the steps: obtaining a to-be-processed medical image, and processing the to-be-processed medical image to obtain a to-be-predicted image; performing three-dimensional segmentation on the to-be-predicted image based on a U-Net image recognition model to obtain an aneurysm three-dimensional image; measuring aneurysm geometrical characteristics of the aneurysm three-dimensional image through deep learning to obtain geometrical index data and hemodynamic data of the aneurysm and the aneurysm carrying blood vessel; and analyzing the geometric index data and the hemodynamic data of the aneurysm-carrying blood vessel and the aneurysm through deep learning to obtain a prediction result of the aneurysm rupture potential. According to the method for predicting the rupture potential of the aneurysm, the problem that the rupture potential of the aneurysm cannot be accurately predicted in the prior art is solved.

The invention relates to a treatment instrument used for a human body lumen disease. The treatment instrument comprises a delivery tube, a catheter base and a wire delivery assembly. The wire delivery assembly comprises a grid tubular structure, a three-way seal valve, a guide tube and a lead-in wire. The grid tubular structure is arranged at one end close to the guide tube base, a coating is arranged on the surface of the grid tubular structure, micro holes are formed in the coating, and the coating comprises medicines, anti-coagulation substances, anti-bacterial substances, substances for promoting vascularization or substances for restraining the vascularization, so that different purposes of treatment are achieved. The defects of a spring coil and a covered stent are overcome, the normal anatomical structure of the vessels is reconstructed, and besides normal blood supplying of the collateral branch vessels is not affected. The treatment instrument has the advantages that a reliable entire occlusion rate of the radiography is obtained; a long-term stable effect is achieved; the treatment instrument is especially suitable for treating most of complex arterial aneurysms; complications at the later period are few; safety is high. The operation process is simple, cost is saved, and wide market prospects and good social effects are achieved.

The invention relates to an intracranial aneurysm morphological parameter semi-automatic measurement method, which comprises the following steps of: A1, acquiring a first aneurysm diameter plane and a first blood flow direction vector based on a first mask combination of a single aneurysm; a2, based on the first aneurysm diameter plane, the first blood flow direction vector and an aneurysm mask in the first mask combination, according to a calculation rule of each parameter value in the parameter information, acquiring parameter information of the aneurysm; a3, based on predefined conditions of an aneurysm external rectangular frame, according to the first aneurysm diameter plane, the first blood flow direction vector and an aneurysm mask in the first mask combination, obtaining the aneurysm external rectangular frame; and A4, based on the first mask combination, the aneurysm external rectangular frame and the parameter information of the aneurysm, outputting a visual result for a doctor to check. According to the method, the tool is manually adjusted to assist the segmentation of the aneurysm and the tumor-carrying blood vessel, so that the accuracy of parameter calculation is ensured.

The invention provides an aneurysm blocking device which is formed by an elastic net-shaped body, the near end of the elastic net-shaped body is folded inwards in the radial direction to be connected with a near-end marking part, the far end of the elastic net-shaped body is folded inwards in the radial direction to be connected with a far-end marking part and folded reversely, the far end of the elastic net-shaped body where the far-end marking part is located extends into the elastic net-shaped body, a double-layer net structure formed through reverse folding forms an expansion part elastic net-shaped body, a single-layer net structure which is not reversely folded forms a neck elastic net-shaped body, and in the self-expansion state, the radial size of the expansion part elastic net-shaped body is gradually increased from the near end to the far end or is increased firstly and then reduced. According to the blocking device capable of effectively treating the aneurysm, the problems that in the prior art, the blocking effect is poor, the operation cost is high, and the operation difficulty is large are solved, the possibility of arterial thrombosis can be reduced, and the risk that the aneurysm top is weak and prone to being broken is reduced.