9 results about "Aneurysm treatment" patented technology

This invention provides an aneurysm embolization auxiliary device, belonging to the field of medical device technology. The device includes a delivery catheter, an operating handle, a balloon, and a filling unit. The delivery catheter delivers a treatment device to the aneurysm location. The operating handle is located at the proximal end of the delivery catheter. The balloon, after inflation, supports the blood vessel. The filling unit fills the aneurysm with an injectable gel for treating the aneurysm from the operating handle location along the delivery catheter. The injectable gel solidifies within the aneurysm. During operation, the delivery catheter delivers the balloon to the aneurysm location. After inflation, the balloon supports and positions the blood vessel. The filling unit fills the aneurysm with the injectable gel, which solidifies upon entering the aneurysm to treat it. This invention primarily addresses technical problems in existing interventional aneurysm treatment methods, such as easy displacement of coils and the increased risk of bleeding due to the need for long-term medication after stent implantation.

Method of endovascular treatment of an aneurysm having a sac with a neck in fluid communication with a parent vessel. A delivery catheter is navigated through the vasculature to the aneurysm. Next, a delivery system is advanced through the delivery catheter to the aneurysm. A liquid metal embolic is injected via the delivery system into the aneurysm with the injected liquid metal embolic at least partially filling the aneurysm. Optionally, a liquid metal embolic seepage preventative element (e.g., radially self-expanding braided structure or plurality of radially self-expanding coils) may be deployed in the aneurysm prior to the injection of the liquid metal embolic prohibiting the liquid metal embolic injected in the aneurysm from entering the parent vessel.

Treatment of aneurysms can be improved by delivering an occlusive member (e.g., an expandable braid) to an aneurysm sac in conjunction with an embolic element (e.g., coils, embolic material). A treatment system for such treatment can include an electrolytically corrodible core wire having a proximal portion, a distal portion, and a detachment zone between the proximal portion and the distal portion. An occlusive member having a proximal hub is coupled to the core wire distal portion. A conduit extends along at least a portion of the core wire. The conduit has a lumen configured to pass an embolic element therethrough.

A therapeutic drug useful for the treatment of aneurysms is provided. The pharmaceutical composition for the treatment and / or prevention of aneurysms comprises at least one of the following drugs as an active ingredient(s): i) drugs targeting platelet-derived growth factor receptor β (PDGFRβ); ii) drugs that inhibit the function of desmoyokin (AHNAK); and iii) drugs that inhibit signaling enhanced by mutations in PDGFRβ or AHNAK.

Treatment of aneurysms can be improved by delivering an occlusive member (e.g., an expandable braid) to an aneurysm sac in conjunction with an embolic element (e.g., coils, embolic material). A treatment system for such treatment can include an electrolytically corrodible core wire having a proximal portion, a distal portion, and a detachment zone between the proximal portion and the distal portion. An occlusive member having a proximal hub is coupled to the core wire distal portion. A conduit extends along at least a portion of the core wire. The conduit has a lumen configured to pass an embolic element therethrough.

The invention relates to the technical field of aneurysm treatment equipment, in particular to an intracranial aneurysm plugging device and a use method thereof. The plugging device comprises a support rod body, the support rod body is of a cylindrical structure, and at least one of the two ends of the support rod body is of a flaring structure; the local film covering part is located in the middle area of the stent rod body, and a covering film is arranged on the portion, where the local film covering part is located, of the stent rod body. In the plugging device, the local film covering part is only arranged in the middle area of the stent rod body, so that the local film covering part can accurately plug the aneurysm, hemodynamics can be changed, the aneurysm and blood circulation can be isolated to prevent rupture, and the space occupying effect caused by filling materials in the aneurysm sac can be thoroughly avoided; and the risk of pressing surrounding brain tissues is avoided.

The application provides an intracranial aneurysm occlusion device, belonging to the technical field of interventional medical instruments; the intracranial aneurysm occlusion device comprises an intratumor part, an extratumor occlusion part, a connecting part, a delivery guide wire and a delivery catheter; the intratumor part and the extratumor occlusion part both have a contracted state and an expanded state; the intratumor part is arranged in the inner cavity of the aneurysm; the extratumor occlusion part is used for pressing the outer side wall of the aneurysm entrance; the connecting part is arranged between the intratumor part and the extratumor occlusion part and is used for connecting the intratumor part and the extratumor occlusion part; the extratumor occlusion part can move on the connecting part to adjust the distance from the intratumor part; the distal end of the delivery guide wire is detachably fixedly connected with the proximal end of the connecting part; the delivery catheter is used for containing the intratumor part and the extratumor occlusion part in the compressed state; and the technical problem that the existing intracranial aneurysm treatment device cannot effectively prevent blood flow from further flowing into the aneurysm and cause damage to the aneurysm is solved.

The invention relates to the technical field of medical instruments, and discloses a pseudoaneurysm treatment device which comprises a trocar system and an injection needle. The trocar system comprises a cannula, a puncture needle, a plugging needle and a blunt needle, and the puncture needle, the plugging needle and the blunt needle can move in the cannula; the front end of the puncture needle is a sharp head; a balloon is arranged at the front end of the plugging needle body; the front end of the blunt needle is blunt and is used for smearing thrombin; the injection needle is used for injecting thrombin into the pseudoaneurysm. The trocar system is used for achieving puncture and blocking and blood coagulation of the joint of the pseudoaneurysm and the artery, thrombin is injected into the pseudoaneurysm through the injection needle, the blood coagulation area can be limited in the pseudoaneurysm, and the reliability of pseudoaneurysm treatment is improved.

The application provides an application of a peripheral blood biomarker combination in construction of a prediction model for intracranial aneurysm rupture, solves the problems of the existing intracranial unruptured aneurysm prediction method and the lack of related early warning biomarkers in the prediction model, and the technical scheme is as follows: an application of a biomarker combination in construction of a prediction model for intracranial aneurysm rupture, the biomarker combination is factor: GPC1, ECM2 and PLEC, a prediction model for predicting intracranial aneurysm rupture is constructed based on the biomarker, and the application and application method in detection reagents and kits have the advantages and positive effects that the rupture of an aneurysm is predicted early, the pain of a patient is reduced, and a reference basis is provided for individualized diagnosis and treatment; the prediction model constructed by the biomarkers has the characteristics of high sensitivity and good specificity, and is significantly better than the PHASES scoring method and the unruptured intracranial aneurysm treatment scoring method.