38 results about "Parent vessel" patented technology

Embolic implants, delivery systems and methods of manufacture and delivery are disclosed. The devices can be used for aneurysm treatment and / or parent vessel occlusion. Implant designs offer low profile compressibility for delivery to neurovasculature, while maintaining other necessary features such as density for occlusion purposes and desirable radial strength characteristics.

The initial deployment of a self-expanding stent is performed by the physician manually retracting the sheath of a delivery system. This provides the physician with complete control of the initial deployment of the stent. Further, once the stent is securely engaged within the parent vessel, the remaining deployment over the remaining length of the stent is performed automatically by retraction of the sheath by a spring. Since the physician simply initiates the deployment of the stent, the deployment is readily performed using only a single hand of the physician.

Embolic implants, delivery systems and methods of manufacture and delivery are disclosed. The devices can be used for aneurysm treatment and / or parent vessel occlusion. Implant designs offer low profile compressibility for delivery to neurovasculature, while maintaining other necessary features such as density for occlusion purposes and desirable radial strength characteristics.

Embolic implants, delivery systems and methods of manufacture and delivery are disclosed. The devices can be used for aneurysm treatment and / or parent vessel occlusion. Implant designs offer low profile compressibility for delivery to neurovasculature, while maintaining other necessary features such as density for occlusion purposes and desirable radial strength characteristics.

A method and a system are disclosed for labeling an anatomical point associated with a lesion in an organ such as a lung. The method includes: a segmentation of a vessel tree anatomical structure starting from an autonomously determined initial image point; labeling the vessel segments of the vessel tree segmentation with segment labels based on a priori anatomical knowledge, thereby creating an individualized anatomical model; receiving a user-specified image point having a location from a user and locating a nearby vessel structure; tracking along the vessel structure in a direction towards a root of a parent vessel tree until a prior labeled vessel segment is encountered in the anatomical model, and assigning the label of the encountered prior labeled vessel segment from the anatomical model as an anatomical location label of the user-specified image point.

The vasoocclusive apparatus can be used in a method of interventional therapy and vascular surgery by inserting the apparatus into a portion of a vasculature, for treatment of a body vessel such as an aneurysm in conjunction with a secondary vasoocclusive device to be placed within the vessel. The vasoocclusiveVasooclusive apparatus includes a plurality of strut members connected together at a central hub that extend from a collapsed position to an expanded configuration to cross the neck of the aneurysm, dividing the neck into smaller openings, allowing the deployment of the secondary vasoocclusive device within the aneurysm but preventing migration of the secondary vasoocclusive device from the aneurysm. The strut members can be made from a twisted cable of strands of a superelastic material, such as a shape memory nickel titanium alloy, with at least one radiopaque strand. A shape memory collar is provided for detachably mounting the vasoocclusive apparatus to a pusher member and for detaching the vasoocclusive apparatus for deployment when a desired placement within an aneurysm to be treated and out of a parent vessel is achieved.

Microvessel networks are produced in vitro from tissue-engineered parent vessels sprouting into a supporting matrix, as for example gels, of extracellular matrix proteins. The microvessel systems are integrated into devices that allow for controlled perfusion with fluids. The vessels may include cells from one cell type, for example, endothelial cells, or from combinations of two or more cell types.

An occlusion system, method, and apparatus which treats an aneurysm in a primary vessel such as an intracranial vessel. Aneurysm types treatable by means of this invention include bulge (sometimes referred to as a true aneurysm), dissecting aneurysms in which the layers of vessel wall are partially delaminated, and what are referred to a “false” aneurysm defined by a relatively small opening in the parent vessel wall fluridically coupled to a bulb-shaped sac, also defined by the vessel wall. The system includes an occlusion device configured for deployment in the parent vessel that restricts fluid flow to the aneurysm. A patch on the device covers the neck of the aneurysm. The system includes a marker in a defined relationship with the patch, which allows for axial and rotational positioning of the device.

Implantable therapeutic devices and methods for endovascular placement of devices at a target site, such an opening at a neck of an aneurysm, are disclosed. Selected embodiments of the present technology have closures (102) that at least partially occlude the neck of an aneurysm to stabilize embolic or coagulative treatment of the aneurysm. In one embodiment, for example, an aneurysm closure device comprises a closure structure (102) and a supplemental stabilizer (103). The closure structure can have a curved portion configured to extend along a first vessel, such as a side branch of a bifurcated vessel that extends along a lateral axis (T). The supplemental stabilizer extends from the closure structure along a longitudinal axis (L) transverse to the lateral axis of the first vessel. The supplemental stabilizer is configured to exert an outward force against a second vessel, such as a parent vessel, that extends transversely to the first vessel.

An occlusion system, method, and apparatus which treats an aneurysm in a primary vessel such as an intracranial vessel. Aneurysm types treatable by means of this invention include bulge (sometimes referred to as a true aneurysm), dissecting aneurysms in which the layers of vessel wall are partially delaminated, and what are referred to a "false" aneurysm defined by a relatively small opening in the parent vessel wall fluridically coupled to a bulb-shaped sac, also defined by the vessel wall. The system includes an occlusion device configured for deployment in the parent vessel that restricts fluid flow to the aneurysm. A patch on the device covers the neck of the aneurysm. The system includes a marker in a defined relationship with the patch, which allows for axial and rotational positioning of the device.

The initial deployment of a self-expanding stent is performed by the physician manually retracting the sheath of a delivery system. This provides the physician with complete control of the initial deployment of the stent. Further, once the stent is securely engaged within the parent vessel, the remaining deployment over the remaining length of the stent is performed automatically by retraction of the sheath by a spring. Since the physician simply initiates the deployment of the stent, the deployment is readily performed using only a single hand of the physician.

The present application discloses a surgical apparatus for aneurysms comprising: a stent, a delivery guide wire, an introducer sheath and a microcatheter, wherein: the stent is a self-expanding stent; the delivery guide wire outside of which the stent is restrained to is provided in a lumen of the introducer sheath; the introducer sheather is connected with the microcatheter, with lumnes communicating, to form a passageway through which the delivery guide wire and the stent are delivered into a human body. The surgical apparatus for aneurysms provided in the examples of the present application is able to deliver and release the stent which has high density and is super soft to a vascular lesion. A lattice structure of the stent is of high coverage at the vascular lesion such that the stent released into the vessel prodeces the same effects as healing of parent vessel, and thus improves the treatment of vascular aneurysms.

An occlusive device suitable for endovascular treatment of an aneurysm in a region of a parent vessel in a patient, including a structure having a fixed porosity and having dimensions suitable for insertion into vasculature of the patient to reach the region of the aneurysm in the parent vessel. The device further includes a frangible material supported by the structure which initially provides a substantial barrier to flow through the frangible material and is capable of at least one of localized rupturing and localized eroding, in the presence of a pressure differential arising at an ostium of a perforator vessel communicating with the parent vessel, within an acute time period to minimize ischemia downstream of the perforator vessel.

A method of using a delivery system includes advancing a stent to be located within an ostium of a vessel; advancing a basket actuation button of a handle to deploy a basket of the basket assembly; moving the basket into engagement with a parent vessel, the basket having a larger diameter than a diameter of the ostium; deploying the stent within an ostial lesion of the vessel; and contracting the basket.

Implantable therapeutic devices and methods for endovascular placement of devices at a target site, such an opening at a neck of an aneurysm, are disclosed. Selected embodiments of the present technology have closures (102) that at least partially occlude the neck of an aneurysm to stabilize embolic or coagulative treatment of the aneurysm. In one embodiment, for example, an aneurysm closure device comprises a closure structure (102) and a supplemental stabilizer (103). The closure structure can have a curved portion configured to extend along a first vessel, such as a side branch of a bifurcated vessel that extends along a lateral axis (T). The supplemental stabilizer extends from the closure structure along a longitudinal axis (L) transverse to the lateral axis of the first vessel. The supplemental stabilizer is configured to exert an outward force against a second vessel, such as a parent vessel, that extends transversely to the first vessel.

A method for creating networks of perfusable microvessels in vitro. A mandrel is drawn through a matrix to form a channel through the matrix. Cells are injected into the channel. The matrix is incubated to allow the cells to attach inside the channel. The channel is perfused to remove unattached cells to create a parent vessel, where the parent vessel includes a perfusable hollow channel lined with cells in the matrix. The parent vessel is induced to create sprouts into the surrounding matrix gel so as to form a microvessel network. The microvessel network is subjected to luminal perfusion through the parent vessel.

A method for creating networks of perfusable microvessels in vitro. Cells including cell types capable of sprouting are seeded 1300 into a channel in a matrix at to activate competency 1304 of the cells for sprouting as microvessels based on the seeding density. The matrix channel is perfused with medium to allow parent vessels to form and for viability 1324. The parent vessels and matrix are incubated and perfused to provide for sprouting of microvessels from parent vessels into the surrounding matrix 1328. The sprouting parent vessels are grown until network forms 1332.

A method and a system are disclosed for labeling an anatomical point associated with a lesion in an organ such as a lung. The method includes: a segmentation of a vessel tree anatomical structure starting from an autonomously determined initial image point; labeling the vessel segments of the vessel tree segmentation with segment labels based on a priori anatomical knowledge, thereby creating an individualized anatomical model; receiving a user-specified image point having a location from a user and locating a nearby vessel structure; tracking along the vessel structure in a direction towards a root of a parent vessel tree until a prior labeled vessel segment is encountered in the anatomical model, and assigning the label of the encountered prior labeled vessel segment from the anatomical model as an anatomical location label of the user-specified image point.

Systems and methods provide a novel computational approach to planning the endovascular treatment of cardiovascular diseases. In particular, the invention simulates medical device deployment and hemodynamic outcomes using a virtual patient-specific anatomical model of the area to be treated, high-fidelity finite element medical device models and computational fluid dynamics (CFD). In an embodiment, the described approach investigates the effects of coil packing density, coil shape, aneurysmal neck size and parent vessel flow rate on aneurysmal hemodynamics. A processor may receive patient clinical data used to construct the relevant anatomical structure model. The processor may access medical device models constructed using finite element analysis and three dimensional beam analysis, and simulates the deployment of selected medical devices in the anatomical structure model. The selected medical device models and the anatomical structure model mesh, allowing the processor to simulate hemodynamic outcomes using computational fluid dynamics.

A method for creating networks of perfusable microvessels in vitro. Cells including cell types capable of sprouting are seeded 1300 into a channel in a matrix at to activate competency 1304 of the cells for sprouting as microvessels based on the seeding density. The matrix channel is perfused with medium to allow parent vessels to form and for viability 1324. The parent vessels and matrix are incubated and perfused to provide for sprouting of microvessels from parent vessels into the surrounding matrix 1328. The sprouting parent vessels are grown until network forms 1332.

Systems and methods provide a novel computational approach to planning the endovascular treatment of cardiovascular diseases. In particular, the invention simulates medical device deployment and hemodynamic outcomes using a virtual patient-specific anatomical model of the area to be treated, high-fidelity finite element medical device models and computational fluid dynamics (CFD). In an embodiment, the described approach investigates the effects of coil packing density, coil shape, aneurysmal neck size and parent vessel flow rate on aneurysmal hemodynamics. A processor may receive patient clinical data used to construct the relevant anatomical structure model. The processor may access medical device models constructed using finite element analysis and three dimensional beam analysis, and simulates the deployment of selected medical devices in the anatomical structure model. The selected medical device models and the anatomical structure model mesh, allowing the processor to simulate hemodynamic outcomes using computational fluid dynamics.

A framework for isolating an aneurysm and parent vessel in volumetric image data is provided herein. In accordance with one aspect, the framework generates a refined mask by performing region growingstarting at an aneurysm dome point to eliminate vessels that are indirectly connected to an aneurysm or parent vessel in volumetric image data. A final mask may be generated based at least in part onthe refined mask by eliminating any kissing vessel connected with the aneurysm from the refined mask. The final mask may then be used for segmentation of the aneurysm and the parent vessel in the volumetric image data.

The invention provides a device for forming a light-selective absorbing coating on the surface of a wide-format metal base strip, which includes a coating tank with a first aluminum strip inlet and a first aluminum strip exit on opposite sides, and the coating tank is divided into two parts. It is a sub-slot and a mother slot. The sub-slot is placed slightly above the mother slot. On the opposite sides of the sub-slot, corresponding to the first aluminum strip entrance and the first aluminum strip exit, the second aluminum strip entrance and the second aluminum strip entrance are also provided. Two aluminum strip outlets; it also includes a plating solution circulation pump, the suction port of the plating solution circulation pump is placed in the main tank, and the output port is placed in the sub tank; The second aluminum strip inlet and the second aluminum strip outlet naturally overflow into the mother tank, the invention does not need guide rollers, and the metal aluminum plate to be plated does not need to be turned over in the plating tank, and is always in a stable and smooth state, which is convenient The target coating with superior surface deposition performance is especially suitable for the surface coating of wide-format metal substrates, especially the production of light-selective absorption coatings.

Microvessel networks are produced in vitro from tissue-engineered parent vessels sprouting into a supporting matrix, as for example gels, of extracellular matrix proteins. The microvessel systems are integrated into devices that allow for controlled perfusion with fluids. The vessels may include cells from one cell type, for example, endothelial cells, or from combinations of two or more cell types.

The embodiment of this specification provides a method and system for measuring morphological parameters of an intracranial aneurysm image. The embodiment of this specification solves the problem that the measurement of the morphological parameters of the intracranial aneurysm image cannot be fully automated and the measurement consistency is difficult to guarantee by measuring the morphological parameters of the intracranial aneurysm image. The measurement method includes: segmenting the intracranial parent vessel image from MRA three-dimensional DICOM data; segmenting the intracranial aneurysm image based on the center line and radius of the intracranial tumor parent vessel; The scientific parameters are measured. The method and system for measuring the morphological parameters of intracranial aneurysm images provided in the embodiments of this specification can realize the automation of intracranial aneurysm image measurement, quickly measure the morphological parameters of intracranial aneurysm images, and ensure the accuracy of aneurysm images. Consistency of measurements of morphological parameters.

An occlusive device suitable for endovascular treatment of an aneurysm in a region of a parent vessel in a patient, including a structure having a pre-established pore features and having dimensions suitable for insertion into vasculature of the patient to reach the region of the aneurysm in the parent vessel. The device further includes a frangible material associated with the pore features which initially provides a substantial barrier to flow through the frangible material and is capable of at least one of localized rupturing and localized eroding, in the presence of a pressure differential arising at an ostium of a perforator vessel communicating with the parent vessel, within an acute time period to minimize ischemia downstream of the perforator vessel.