7 results about "Internal iliac aneurysm" patented technology

This invention provides an auxiliary stent for intracranial aneurysm embolization, belonging to the field of medical device technology. The stent includes a stent body, which extends axially and includes a first anchoring section, a support section, a second anchoring section, and a third anchoring section integrally arranged sequentially. The first anchoring section has a semi-open loop structure and forms a funnel-shaped structure. The support section has a closed loop structure and is positioned at least directly opposite the neck of the aneurysm to provide the main radial support force to resist the outward pressure of the spring coil. The second anchoring section has a semi-open loop structure and a funnel-shaped structure. The third anchoring section has an open loop structure and forms a continuous funnel-shaped structure with the second anchoring section. Through its segmented structural design, this invention significantly improves the apposition and positional stability within the blood vessel, thereby effectively reducing the risk of complications related to stent displacement and poor apposition.

The invention relates to an intracranial aneurysm in-vitro amplification model blood circulation experiment system and method, and the system comprises an intracranial aneurysm in-vitro amplification model, a peristaltic pump, a liquid storage tank, a flow detection part and a pressure detection part, one end of the pump pipe is connected with an outlet of the liquid storage tank, the other end of the pump pipe is connected with an inlet of the intracranial aneurysm in-vitro amplification model, and an outlet of the intracranial aneurysm in-vitro amplification model is connected with an inlet of the liquid storage tank to form an extracorporeal circulation path. The experimental method comprises the steps of model and boundary condition zooming, blood flow simulation system construction, in-vitro patient specificity model and circulation path establishment, real-time monitoring and data acquisition. On the premise of meeting a flow similarity criterion, amplification construction of a patient specific aneurysm model, accurate simulation of physiological pulsating blood flow and systematic monitoring of key hemodynamic parameters can be realized; therefore, an in-vitro experiment platform which is more reliable and closer to the physiological state is provided for hemodynamic research of intracranial aneurysm.

The invention relates to the technical field of intratumoral treatment instruments, and discloses a woven intratumoral embolism device which comprises a plurality of woven balls arranged in series, each woven ball is formed by integrally weaving a plurality of wires, and the distance between every two adjacent woven balls is larger than the weaving radius of a single woven ball. The embolism device is shaped through a high-temperature heat treatment tool in the preparation process, the initial shape of the shaped embolism device is a sphere-like shape or a shape in which the packing state can be adjusted by applying tension, the embolism device is in a straightened state in a guide-in sheath, and the embolism device is self-adaptive to the aneurysm shape and achieves one-time complete embolism after being conveyed into the aneurysm through a micro catheter. The problems that due to the fact that an existing metal spring ring needs to be filled for multiple times when used for treating intracranial aneurysm, the operation time is long, the risk is high, and an existing intra-tumor embolization device is poor in aneurysm form compliance and difficult in model selection are solved.

The invention relates to the technical field of aneurysm treatment equipment, in particular to an intracranial aneurysm plugging device and a use method thereof. The plugging device comprises a support rod body, the support rod body is of a cylindrical structure, and at least one of the two ends of the support rod body is of a flaring structure; the local film covering part is located in the middle area of the stent rod body, and a covering film is arranged on the portion, where the local film covering part is located, of the stent rod body. In the plugging device, the local film covering part is only arranged in the middle area of the stent rod body, so that the local film covering part can accurately plug the aneurysm, hemodynamics can be changed, the aneurysm and blood circulation can be isolated to prevent rupture, and the space occupying effect caused by filling materials in the aneurysm sac can be thoroughly avoided; and the risk of pressing surrounding brain tissues is avoided.

The application provides an intracranial aneurysm occlusion device, belonging to the technical field of interventional medical instruments; the intracranial aneurysm occlusion device comprises an intratumor part, an extratumor occlusion part, a connecting part, a delivery guide wire and a delivery catheter; the intratumor part and the extratumor occlusion part both have a contracted state and an expanded state; the intratumor part is arranged in the inner cavity of the aneurysm; the extratumor occlusion part is used for pressing the outer side wall of the aneurysm entrance; the connecting part is arranged between the intratumor part and the extratumor occlusion part and is used for connecting the intratumor part and the extratumor occlusion part; the extratumor occlusion part can move on the connecting part to adjust the distance from the intratumor part; the distal end of the delivery guide wire is detachably fixedly connected with the proximal end of the connecting part; the delivery catheter is used for containing the intratumor part and the extratumor occlusion part in the compressed state; and the technical problem that the existing intracranial aneurysm treatment device cannot effectively prevent blood flow from further flowing into the aneurysm and cause damage to the aneurysm is solved.

The application relates to an intracranial aneurysm microfluidic blood vessel chip, system, preparation method and application, and belongs to the medical technical field.The intracranial aneurysm microfluidic blood vessel chip comprises a Y-shaped microfluidic channel, a negative pressure suction cavity and an elastic film, the negative pressure suction cavity is used for being connected with a negative pressure suction device to vacuumize the negative pressure suction cavity, the Y-shaped microfluidic channel meets at a crossing, the crossing is provided with an opening, the elastic film is arranged at the opening and separates the negative pressure suction cavity from the Y-shaped microfluidic channel, the elastic film is a treated polyisoprene film, and the treatment comprises plasma treatment; when the negative pressure suction cavity generates negative pressure, the elastic film can bulge towards the negative pressure suction cavity, and has different bulging degrees under different sizes of negative pressure. The application has good biocompatibility, can simulate the continuous change of a tumor, and has consistency with the intracranial aneurysm in the body in terms of hemodynamic characteristics.

The application provides an application of a peripheral blood biomarker combination in construction of a prediction model for intracranial aneurysm rupture, solves the problems of the existing intracranial unruptured aneurysm prediction method and the lack of related early warning biomarkers in the prediction model, and the technical scheme is as follows: an application of a biomarker combination in construction of a prediction model for intracranial aneurysm rupture, the biomarker combination is factor: GPC1, ECM2 and PLEC, a prediction model for predicting intracranial aneurysm rupture is constructed based on the biomarker, and the application and application method in detection reagents and kits have the advantages and positive effects that the rupture of an aneurysm is predicted early, the pain of a patient is reduced, and a reference basis is provided for individualized diagnosis and treatment; the prediction model constructed by the biomarkers has the characteristics of high sensitivity and good specificity, and is significantly better than the PHASES scoring method and the unruptured intracranial aneurysm treatment scoring method.