25 results about "Internal iliac aneurysm" patented technology

The invention discloses an intracranial aneurysm rupture risk assessment method, device and equipment and a storage medium, and the method comprises the steps: firstly, generating a time sequence image containing flow field information based on the maximum density projection and center line extraction processing of a two-dimensional angiography image sequence in combination with contrast agent concentration change curve analysis; performing three-dimensional reconstruction, region-of-interest extraction and opening extension processing by using the three-dimensional image sequence to obtain detailed morphological parameters and a region-of-interest model after extension processing; secondly, displaying a time sequence image with flow field information and a region-of-interest model of which an opening is not prolonged in an overlapping manner, further optimizing setting of boundary conditions and performing hydrodynamic simulation by calculating a flow field vector in an observation ball and determining an actual blood flow direction, and calculating key hemodynamic parameters; and finally, in combination with the morphological parameters, the hemodynamic parameters and clinical information of the patient, obtaining an evaluation result of the aneurysm rupture risk.

The invention belongs to the technical field of medical image segmentation, and relates to an intracranial aneurysm image detection method, system and device and a storage medium. The invention designs a new network architecture, namely a multi-scale axial residual projection network, which is used for improving the accuracy of intracranial aneurysm detection and segmentation. In the aspect of model input, preprocessing steps including matched filtering, Gaussian filtering and Laplacian filtering are adopted for enhancing blood vessel structure and edge information and reducing computing resource requirements. In the aspect of a model structure, multi-scale feature extraction is realized by using a DWR module, and the segmentation capability of the model on a small target is enhanced; besides, the ACRE module is used for enhancing the foreground and inhibiting the background through the axial attention module and the context relation encoder module, and the processing capacity of the network for the edge information of the foreground is improved. According to the invention, the accuracy of intracranial aneurysm detection and segmentation can be improved.

The invention discloses an intracranial aneurysm detection method and device based on a bottom double-branch network and confidence coefficient calibration, and the method comprises the steps: carrying out the low-dimensional feature extraction of an image in the bottom double-branch network, and obtaining a feature map, dividing the feature map into a first sub-feature map and a second sub-feature map, and performing feature extraction and fusion through different convolution operation branches to obtain a final feature map; performing prediction and matching of a real bounding box through an optimal transmission algorithm, and training a bottom double-branch network according to a matching result; in the bottom double-branch network training process, confidence coefficient calibration is carried out at the output end of the model by constructing a loss function based on confidence coefficient scores, and finally the trained bottom double-branch network is obtained to serve as an intracranial aneurysm detection model; and inputting the new to-be-detected picture into the intracranial aneurysm detection model, and detecting to obtain a high-confidence-coefficient intracranial aneurysm prediction bounding box so as to accurately position the intracranial aneurysm. According to the invention, the accuracy and reliability of intracranial aneurysm detection can be obviously improved.

Systems and methods for treating an aneurysm in accordance with embodiments of the present technology include intravascularly delivering an occlusive member to an aneurysm cavity and deforming a shape of the occlusive member via introduction of an embolic element to a space between the occlusive member and an inner surface of the aneurysm wall.

The present invention relates to an integrated device for assisting in the formation of the aneurysm neck of an intracranial aneurysm and a method for using the same. The device includes a tip, a stent, a delivery tube, a traction wire, a connecting member, a locking sleeve, and a support wire. The tip, the stent, and the delivery tube are connected in sequence from the distal end to the proximal end. The traction wire passes through the tip, the stent, and the delivery tube and exits from the delivery tube. The support wire is connected to the delivery tube through the connecting member. The locking sleeve is sleeved outside the traction wire and the support wire and is used to control the locking or loosening of the traction wire and the support wire. An electrolytic detachment area is provided between the distal end wire winding section of the stent and the traction wire, and a hydrolytic detachment area is provided between the proximal end wire winding section of the stent and the delivery tube. The device provided by the present invention can pass through a microcatheter with a smaller diameter; before the coil is implanted, the aneurysm orifice can be fully expanded, which can not only assist the coil filling to avoid insufficient coil filling, but also play a role in guiding blood flow.

The invention provides a method for detecting pressure in an intracranial aneurysm cavity, and belongs to the technical field of pressure detection in an aneurysm cavity. The detection method comprises the following steps: S1, planning an implantation path, positioning an aneurysm focus position under the guidance of image equipment before an operation, and planning the implantation path of a pressure monitoring system; s2, a pressure monitoring system is implanted, a guide catheter is intervened through femoral artery puncture, and the pressure monitoring system is sent to a target blood vessel section; s3, data are collected, and pressure values in the aneurysm cavity and the aneurysm neck opening are collected before the operation, during the operation and after the operation respectively; s4, data analysis: analyzing the collected data so as to respectively determine changes of pressure values in the aneurysm cavity and the aneurysm neck opening before, during and after an operation; the method is mainly used for solving the technical problems that in the prior art, real-time monitoring means for the pressure of an aneurysm cavity is lacked, and the force change in the aneurysm cavity cannot be accurately measured.

A novel shape memory polymer (SMP)-based device for surgical treatment of an intracorporeal defect (e.g., a void or anomaly) such as an intracranial aneurysm or fistula. In at least one non-limiting embodiment, the SMP device is a 3D-printed SMP material sized to specifically fit and thus occlude an intracranial aneurysm (ICA). The SMP device may be delivered to the intracorporeal defect via a catheter having a heating mechanism wherein the SMP device is raised above its glass transition temperature as it is deployed, causing the SMP device to return to its permanent shape after it is deployed into the intracorporeal defect. SMP device delivery systems that include the SMP devices, as well as methods of making and using the devices and systems, are also disclosed.

This invention provides an auxiliary stent for intracranial aneurysm embolization, belonging to the field of medical device technology. The stent includes a stent body, which extends axially and includes a first anchoring section, a support section, a second anchoring section, and a third anchoring section integrally arranged sequentially. The first anchoring section has a semi-open loop structure and forms a funnel-shaped structure. The support section has a closed loop structure and is positioned at least directly opposite the neck of the aneurysm to provide the main radial support force to resist the outward pressure of the spring coil. The second anchoring section has a semi-open loop structure and a funnel-shaped structure. The third anchoring section has an open loop structure and forms a continuous funnel-shaped structure with the second anchoring section. Through its segmented structural design, this invention significantly improves the apposition and positional stability within the blood vessel, thereby effectively reducing the risk of complications related to stent displacement and poor apposition.

The present invention belongs to the technical field of medical image segmentation, and relates to a method, system, device and storage medium for detecting intracranial aneurysm images. The present invention designs a new network architecture, namely a multi-scale axial residual projection network, to improve the accuracy of intracranial aneurysm detection and segmentation. In terms of model input, the present invention adopts preprocessing steps including matched filtering, Gaussian filtering and Laplacian filtering to enhance vascular structures and edge information and reduce the demand for computing resources. In terms of model structure, the present invention uses the DWR module to achieve multi-scale feature extraction and enhance the model's segmentation ability for small targets; in addition, the ACRE module is used to enhance the foreground and suppress the background through the axial attention module and the context relationship encoder module, improving the network's processing ability for the edge information of the foreground. The present invention can significantly improve the accuracy of intracranial aneurysm detection and segmentation.

The utility model discloses a model teaching aid for simulating intracranial aneurysm, which comprises a Willis ring, a traffic artery body, two side cerebral anterior artery initial segments, two side internal carotid artery tail segments, two side posterior traffic artery bodies and two side cerebral posterior artery initial segments, a subarachnoid cavity is arranged on the outer side of a brain tissue body, and the subarachnoid cavity is communicated with the subarachnoid cavity. A brain shell is arranged on the outer side of the subarachnoid cavity, a second demonstration lamp bead is arranged at the subarachnoid cavity, a set of arc supports are arranged at the Willis ring, each arc support is provided with a set of third demonstration lamp beads, a pair of outlet supports are arranged on the outermost arc support, and a pair of third demonstration lamp beads are arranged on the outlet supports. The outer ends of the two outlet supports and between the two outlet supports are connected with a group of connecting supports which are guided to the lower cavity of the arachnoid, and the two outlet supports and the connecting supports are respectively provided with a group of fourth demonstration lamp beads. The device can provide a detailed simulation process from intracranial aneurysm formation to rupture to subarachnoid hemorrhage, and is worthy of popularization and application.

The invention relates to an intracranial aneurysm in-vitro amplification model blood circulation experiment system and method, and the system comprises an intracranial aneurysm in-vitro amplification model, a peristaltic pump, a liquid storage tank, a flow detection part and a pressure detection part, one end of the pump pipe is connected with an outlet of the liquid storage tank, the other end of the pump pipe is connected with an inlet of the intracranial aneurysm in-vitro amplification model, and an outlet of the intracranial aneurysm in-vitro amplification model is connected with an inlet of the liquid storage tank to form an extracorporeal circulation path. The experimental method comprises the steps of model and boundary condition zooming, blood flow simulation system construction, in-vitro patient specificity model and circulation path establishment, real-time monitoring and data acquisition. On the premise of meeting a flow similarity criterion, amplification construction of a patient specific aneurysm model, accurate simulation of physiological pulsating blood flow and systematic monitoring of key hemodynamic parameters can be realized; therefore, an in-vitro experiment platform which is more reliable and closer to the physiological state is provided for hemodynamic research of intracranial aneurysm.

A flow diverter stent apparatus having a substantially tubular body is disclosed. In at least one embodiment, the apparatus provides an at least one braided segment and an at least one laser cut segment engaged with one another in series so as to form an elongate flow diverter stent. During use of the apparatus, with the apparatus positioned within a catheter and moved to a target area of a patient's vascular system, each of the at least one braided segment and at least one laser cut segment is configured for moving into a shape memorized secondary shape capable of filling the target area as the apparatus exits the catheter.

A method for treating an aneurysm in accordance with a particular embodiment of the present technology includes intravascularly delivering a mixture including a biopolymer (e.g., chitosan) and a chemical crosslinking agent (e.g., genipin) to an aneurysm. The method further includes mixing the biopolymer and the chemical crosslinking agent to initiate chemical crosslinking of the biopolymer. The mixture is delivered to the aneurysm via a lumen and an exit port of a catheter while the chemical crosslinking is ongoing. The mixture exits the catheter as a single cohesive strand that at least partially agglomerates to form a mass occupying at least 75% of a total internal volume of the aneurysm. During delivery of the mixture, the method includes expanding a tubular flow diverter to reinforce a neck of the aneurysm.

The invention discloses an intracranial aneurysm automatic segmentation method and system, and the method comprises the steps: constructing a cerebral vessel segmentation pre-training network, obtaining the weight of a pre-training model, and constructing an intracranial aneurysm segmentation network; the aneurysm segmentation network is composed of a double-branch artery-aneurysm encoder and an aneurysm decoder, a grouping self-adaptive inquiry attention mechanism is constructed, aneurysm feature expression is enhanced by using artery features of the encoder, and interference of an artery structure on aneurysm segmentation is reduced; a depth separable cavity convolution module is constructed in a depth supervision framework of an aneurysm decoder, and multi-scale features are captured through three parallel depth separable cavity convolution branches. Modeling is carried out on the context relationship between the intracranial artery structure and the aneurysm, pre-trained blood vessel features are migrated to guide aneurysm segmentation, instability possibly caused by dependence on pre-segmentation of the artery structure is reduced, and accurate segmentation of aneurysms of various sizes is achieved.

The invention relates to the technical field of intratumoral treatment instruments, and discloses a woven intratumoral embolism device which comprises a plurality of woven balls arranged in series, each woven ball is formed by integrally weaving a plurality of wires, and the distance between every two adjacent woven balls is larger than the weaving radius of a single woven ball. The embolism device is shaped through a high-temperature heat treatment tool in the preparation process, the initial shape of the shaped embolism device is a sphere-like shape or a shape in which the packing state can be adjusted by applying tension, the embolism device is in a straightened state in a guide-in sheath, and the embolism device is self-adaptive to the aneurysm shape and achieves one-time complete embolism after being conveyed into the aneurysm through a micro catheter. The problems that due to the fact that an existing metal spring ring needs to be filled for multiple times when used for treating intracranial aneurysm, the operation time is long, the risk is high, and an existing intra-tumor embolization device is poor in aneurysm form compliance and difficult in model selection are solved.

The present invention provides a medical coil, which comprises a spring and at least one radiopaque marker. The radiopaque marker is sleeved outside the spring and / or disposed inside the spring. Thus, on the one hand, the specific position and shape of the medical coil can be observed during or after implantation by means of these radiopaque markers, effectively solving the problem of poor radiopacity of the existing coils. On the other hand, since the radiopaque marker is sleeved outside and / or inside the spring, the setting of the radiopaque marker will not affect the physical properties such as the three-dimensional structure and stiffness of the spring itself, effectively realizing the embolization treatment of intracranial aneurysms.

The invention relates to the technical field of aneurysm treatment equipment, in particular to an intracranial aneurysm plugging device and a use method thereof. The plugging device comprises a support rod body, the support rod body is of a cylindrical structure, and at least one of the two ends of the support rod body is of a flaring structure; the local film covering part is located in the middle area of the stent rod body, and a covering film is arranged on the portion, where the local film covering part is located, of the stent rod body. In the plugging device, the local film covering part is only arranged in the middle area of the stent rod body, so that the local film covering part can accurately plug the aneurysm, hemodynamics can be changed, the aneurysm and blood circulation can be isolated to prevent rupture, and the space occupying effect caused by filling materials in the aneurysm sac can be thoroughly avoided; and the risk of pressing surrounding brain tissues is avoided.

The application provides an intracranial aneurysm occlusion device, belonging to the technical field of interventional medical instruments; the intracranial aneurysm occlusion device comprises an intratumor part, an extratumor occlusion part, a connecting part, a delivery guide wire and a delivery catheter; the intratumor part and the extratumor occlusion part both have a contracted state and an expanded state; the intratumor part is arranged in the inner cavity of the aneurysm; the extratumor occlusion part is used for pressing the outer side wall of the aneurysm entrance; the connecting part is arranged between the intratumor part and the extratumor occlusion part and is used for connecting the intratumor part and the extratumor occlusion part; the extratumor occlusion part can move on the connecting part to adjust the distance from the intratumor part; the distal end of the delivery guide wire is detachably fixedly connected with the proximal end of the connecting part; the delivery catheter is used for containing the intratumor part and the extratumor occlusion part in the compressed state; and the technical problem that the existing intracranial aneurysm treatment device cannot effectively prevent blood flow from further flowing into the aneurysm and cause damage to the aneurysm is solved.

The application relates to an intracranial aneurysm microfluidic blood vessel chip, system, preparation method and application, and belongs to the medical technical field.The intracranial aneurysm microfluidic blood vessel chip comprises a Y-shaped microfluidic channel, a negative pressure suction cavity and an elastic film, the negative pressure suction cavity is used for being connected with a negative pressure suction device to vacuumize the negative pressure suction cavity, the Y-shaped microfluidic channel meets at a crossing, the crossing is provided with an opening, the elastic film is arranged at the opening and separates the negative pressure suction cavity from the Y-shaped microfluidic channel, the elastic film is a treated polyisoprene film, and the treatment comprises plasma treatment; when the negative pressure suction cavity generates negative pressure, the elastic film can bulge towards the negative pressure suction cavity, and has different bulging degrees under different sizes of negative pressure. The application has good biocompatibility, can simulate the continuous change of a tumor, and has consistency with the intracranial aneurysm in the body in terms of hemodynamic characteristics.

The invention discloses a method and device for predicting the recurrence risk after treatment of a small and medium-sized unruptured intracranial aneurysm support spring ring, electronic equipment and a storage medium, and belongs to the field of clinical medicines.The method comprises the steps that parameter values of all prediction parameters of a patient to be evaluated are obtained; wherein the prediction parameters comprise the aneurysm size, the treatment mode, the postoperative immediate occlusion degree and the preoperative high-resolution magnetic resonance blood vessel wall imaging tumor wall strengthening level; determining a target category corresponding to each prediction parameter according to the parameter value of each prediction parameter; according to the target category, based on a preset scoring rule, determining a recurrence risk score of each prediction parameter; according to the recurrence risk score of each prediction parameter, determining the recurrence risk probability of the to-be-evaluated patient after the treatment of the small and medium-sized unbroken intracranial aneurysm stent spring ring; by implementing the method, the problem that the recurrence risk of small and medium-sized unbroken intracranial aneurysm after interventional operation is not accurately predicted in the prior art can be solved.

A virtual angiogram can be performed by simulating transport of contrast agent through a model of a portion of a vasculature of a patient. The simulation can be based on a patient-specific pulsatile flow velocity field of the vasculature portion. At least one contrast retention metric for an aneurysm in the vasculature portion can be determined based on the virtual angiogram. The contrast retention metric can be indicative of flow stagnation in the aneurysm. In some aspects, the aneurysm can be identified as unstable based at least in part on the at least one contrast retention metric. Responsive to the identification, a treatment can be administered for the aneurysm even though it has not yet ruptured. Alternatively or additionally, the aneurysm can be identified as ruptured, for example, to discriminate between multiple potentially-ruptured aneurysms in the patient for treatment.

The application provides an application of a peripheral blood biomarker combination in construction of a prediction model for intracranial aneurysm rupture, solves the problems of the existing intracranial unruptured aneurysm prediction method and the lack of related early warning biomarkers in the prediction model, and the technical scheme is as follows: an application of a biomarker combination in construction of a prediction model for intracranial aneurysm rupture, the biomarker combination is factor: GPC1, ECM2 and PLEC, a prediction model for predicting intracranial aneurysm rupture is constructed based on the biomarker, and the application and application method in detection reagents and kits have the advantages and positive effects that the rupture of an aneurysm is predicted early, the pain of a patient is reduced, and a reference basis is provided for individualized diagnosis and treatment; the prediction model constructed by the biomarkers has the characteristics of high sensitivity and good specificity, and is significantly better than the PHASES scoring method and the unruptured intracranial aneurysm treatment scoring method.

The present invention discloses a method, device, equipment and storage medium for intracranial aneurysm rupture risk assessment. First, based on the maximum intensity projection and centerline extraction processing of a two-dimensional angiographic image sequence, and combined with the analysis of the contrast agent concentration change curve, a time series image containing flow field information is generated; then, three-dimensional reconstruction, region of interest extraction and opening extension processing are performed on the three-dimensional image sequence to obtain detailed morphological parameters and a region of interest model after extension processing; then, the time series image with flow field information is overlapped and displayed with the region of interest model without extended opening, and by calculating the flow field vector sum in the observation sphere to determine the actual blood flow direction, the setting of boundary conditions is further optimized and fluid dynamics simulation is carried out to calculate the key hemodynamic parameters; finally, combining the morphological parameters, hemodynamic parameters and the patient's clinical information, the assessment result of the aneurysm rupture risk is obtained.

This invention is an intrasaccular aneurysm occlusion device with a neck bridge with one or more proximal openings which is inserted into an aneurysm sac to cover the neck of the aneurysm sac. Embolic pieces (or flowable material) are inserted through the openings into the aneurysm sac. The neck bridge can have a convex first shape which is collapsed and inverted into a concave second shape. The neck bridge can be used in combination with a flexible distal net or mesh.

The invention discloses an intracranial aneurysm information processing system and method based on computer assistance, and relates to the technical field of medical information processing. An intracranial aneurysm information processing system based on computer assistance comprises a basic intracranial aneurysm information processing module and a special intracranial aneurysm information processing module. According to the method, the intracranial aneurysm image data, the auxiliary information data and the basic information analysis model are combined, and the feature enhancement and fusion technology is utilized, so that the diagnosis accuracy of the intracranial aneurysm can be remarkably improved; through an analysis result, high-confidence diagnosis information can be obtained; under the condition of low confidence, the special information analysis model can further optimize the diagnosis process, ensure the accuracy of the diagnosis result and reduce errors caused by feature complexity or data noise through a secondary feature processing and special feature recognition technology.