204 results about "Artery aneurysm" patented technology

Provided is a method for generating an aneurysm region including: obtaining an input image; generating a vessel mesh based on the input image; generating a vessel network including a plurality of nodes based on the vessel mesh; and performing image processing on the vessel network to generate an aneurysm region.

Provided is a method for determining a separating plane for separating aneurysm from a parent artery to obtain precise size information of an aneurysm. The method includes generating an aneurysm region including: generating a vessel mesh; generating a centerline based on the vessel mesh; generating a parent artery mesh based on the centerline; and generating a separating plane based on the parent artery mesh to obtain the aneurysm region.

The invention belongs to the technical field of medical instruments, and particularly relates to a dense net support. The dense net support comprises a front fixing section, a blocking section and a rear fixing section, and the blocking section is located between the front fixing section and the rear fixing section. The plugging section is connected with the front fixing section through a front connecting piece, and the plugging section is connected with the rear fixing section through a rear connecting piece; the plugging section is used for plugging an aneurysm position of a blood vessel, the plugging section sequentially comprises an inner layer part, a middle layer part and an outer layer part from inside to outside, the inner layer part adopts an inner layer metal stent, and the outer layer part adopts an outer layer metal stent. The dense net stent can adjust hemodynamics more accurately, and it is ensured that the blood flow of healthy blood vessels is not affected while the aneurysm is closed; the sealing effect of the aneurysm is ensured, and thrombosis is well promoted, so that blocking and healing of the aneurysm are promoted; and the endothelialization process of the stent is facilitated, so that the success rate of fusing the stent into the blood vessel is improved, the effect of completely sealing the aneurysm opening is achieved, and the recurrence risk is reduced.

A system for treatment of an aneurysm includes an intrasaccular device that can be delivered using a catheter. The device can include at least one expandable structure adapted to transition from a compressed configuration to an expanded configuration when released into the aneurysm. The expandable structure can have a specific shape or porosity. Multiple expandable structures can also be used, in which case each of the expandable structures can have a unique shape or porosity profile. The morphology of the aneurysm and orientation of any connecting arteries can determine the type, size, shape, number, and porosity profile of the expandable structure used in treating the aneurysm.

The invention discloses a spatial registration and image fusion method for deep learning based on SS-OCT and TOF data, relates to the technical field of multi-modal medical image processing, and aims to improve alignment and fusion effects based on SS-OCT and TOF blood vessel data. According to the method, firstly, blood vessel features are enhanced through preprocessing, precise registration and fusion of cross-modal data are achieved by combining high-resolution two-dimensional tomography of SS-OCT and three-dimensional blood vessel form data of TOF and utilizing an improved SIFT algorithm and a cross attention Transformer model, and finally a high-precision three-dimensional blood vessel model is generated and can be used for treating cerebrovascular diseases (such as cerebrovascular diseases). Image support with details and a global structure is provided for preoperative planning and intraoperative navigation of a patient (such as aneurysm and stenosis), and the accuracy of diagnosis and treatment is remarkably improved.

The invention provides a micro-catheter shaping method and system for adjuvant therapy of aneurysm and related equipment, and relates to the technical field of image processing, and the micro-catheter shaping method for adjuvant therapy of aneurysm comprises the steps: obtaining an aneurysm to be treated and an image corresponding to a blood vessel where the aneurysm is located; according to the image, performing overall modeling on the aneurysm and a blood vessel where the aneurysm is located to obtain a corresponding global model, the global model including an aneurysm model and a blood vessel model; according to the global model, first key parameters corresponding to the aneurysm model and second key parameters corresponding to the blood vessel model are obtained, the micro catheter is shaped based on the first key parameters and the second key parameters, physical laws and the shaping form of the head end of the aneurysm can be considered, it can be guaranteed that the head end of the micro catheter is fed into the aneurysm, and the shaping accuracy is improved. And the in-place rate and the stability of the operation are improved.

The invention discloses an automatic microcatheter shaping method and device, electronic equipment and a storage medium. The microcatheter automatic shaping method comprises the following steps: acquiring craniocerebral image data containing aneurysm, and performing three-dimensional reconstruction processing on the craniocerebral image data to obtain a blood vessel model; performing aneurysm segmentation on the blood vessel model to obtain an aneurysm segmentation result; a tumor-carrying artery center line is obtained based on the blood vessel model and the aneurysm segmentation result, wherein the tumor-carrying artery center line refers to the center line of the artery where the aneurysm is located; the aneurysm is measured based on the aneurysm-carrying artery center line, the aneurysm segmentation result and the blood vessel model, and an aneurysm measurement result is obtained; the aneurysm measurement result is used for representing morphological information of the aneurysm; and obtaining a target microcatheter shaping scheme based on the aneurysm segmentation result, the aneurysm measurement result and the aneurysm-carrying artery center line. By means of the micro-catheter shaping device, automatic and accurate shaping of the micro-catheter is achieved, the micro-catheter shaping efficiency is improved, and the success rate of an interventional operation is increased.

An implant (1) for influencing the blood flow in the area of aneurysms which are localized at vascular branches of blood vessels. The implant is present in an expanded state, in which it is implanted in the blood vessel, and in a diameter-reduced, stretched state, in which it is movable through the blood vessel or a catheter. The implant (1) has at least three sections (2, 3) which, at least in the expanded state, are tubular and the walls of which are composed of interwoven wires (4) or interconnected struts, with at least two tubular sections (3) branching off from a first tubular section (2). The at least three tubular sections (2, 3) are made up individually and connected to one another at one end in each case in such a way that, in the expanded state, the blood flow through the first tubular section (2) into the tubular sections (3) branching off from the first tubular section (2) is ensured.

The invention provides an intracranial aneurysm plugging device, and belongs to the technical field of interventional medical instruments. An intracranial aneurysm plugging device comprises an intra-aneurysm part, an extra-aneurysm plugging part, a connecting part, a conveying guide wire and a conveying catheter, the intra-aneurysm part and the extra-aneurysm plugging part both have a contraction state and an expansion state, and the intra-aneurysm part is arranged in an inner cavity of a aneurysm body; the outside-tumor plugging part is used for pressing the outer side wall of the tumor body inlet; the connecting part is arranged between the in-tumor part and the out-tumor plugging part and is used for connecting the in-tumor part and the out-tumor plugging part; the out-tumor plugging part can move on the connecting part so as to adjust the distance between the out-tumor plugging part and the in-tumor part; the far end of the conveying guide wire is detachably and fixedly connected with the near end of the connecting part; the conveying catheter is used for containing the in-tumor part and the out-tumor plugging part in a compressed state; the intracranial aneurysm treatment device is used for solving the technical problems that an existing intracranial aneurysm treatment device cannot effectively prevent blood flow from further flowing into a tumor body, and the tumor body is damaged.

An implant for vascular treatment may include a wire having three or more sections, with adjacent sections having different stiffnesses and / or other properties to facilitate treating an aneurysm with a single instance of the wire. As compared to treating aneurysms using multiple coils, the wire having three or more sections may reduce the time required for treatment of the aneurysm.

To provide stent graft systems and methods of placing such stent graft systems for treating aortic aneurysms.SOLUTION: A stent graft system 100 includes a stent graft, an inflatable fill structure 130, and a cuff 140. The inflatable fill structure 130 at least partially surrounds the stent graft. In various arrangements, the inflatable fill structure 130 has a cavity that is bifurcated. A portion of the cavity is configured to receive a branch stent graft for connection to the stent graft. The cuff 140 is fillable and is located outside of the inflatable fill structure 130, and makes it possible to provide a seal with a wall of a blood vessel. The cuff 140 and the inflatable fill structure 130 are separately fillable from each other to different pressures with a fill medium. In various arrangements, the cuff has a tapered shape such that it is wider at one end than at an opposite end when filled with a fill medium.SELECTED DRAWING: Figure 1

This disclosure reveals a method, system, and computer-readable recording medium for the diagnosis of intracranial aneurysms. The method includes: acquiring a first image, the first image being a three-dimensional image having a intracranial aneurysm; generating a mask, and performing intracranial artery segmentation on the first image to obtain a intracranial artery region; using a segmentation model to perform intracranial aneurysm segmentation on the intracranial artery region in the first image to generate a segmentation result; and using a classification model to classify the segmentation result into intracranial aneurysm and non-intracranial aneurysm, and screening out a true positive result from the classification result. This disclosure proposes an artificial intelligence platform-based intracranial aneurysm assisted diagnosis model, optimizing the intracranial aneurysms recognition process and significantly improving the accuracy of intracranial aneurysms recognition.

The embodiment of the invention discloses an aneurysm rupture risk prediction device, a model training device and a storage medium. The prediction device comprises a first three-dimensional model construction module used for constructing a three-dimensional fluid model and a three-dimensional solid model based on target artery three-dimensional imaging data; the first fluid-solid coupling simulation model building module is used for building a computational fluid dynamics simulation module based on a three-dimensional fluid model, building a static solid analysis simulation module based on a three-dimensional solid model and then building a one-way fluid-solid coupling simulation model; the first index parameter acquisition module is used for taking the blood flow velocity distribution in the target arterial blood vessel in space and time as the input of the fluid-solid coupling simulation model to obtain a hemodynamic index parameter and a solid mechanics index parameter; and the risk prediction module is used for predicting the rupture risk of the aneurysm based on the hemodynamic index parameters and the solid mechanics index parameters. According to the technical scheme, the prediction accuracy of the aneurysm rupture risk can be improved.

The invention relates to the technical field of medical health, and discloses a health assessment system and method based on multi-dimensional retinal aortic aneurysm monitoring data, and the method comprises the steps: collecting a retinal image of a patient with retinal aortic aneurysm, and extracting the aortic aneurysm features of the patient with retinal aortic aneurysm, setting an eye dynamic monitoring network of the patient with the greater aneurysm of the retina; performing time synchronization processing on the iconography image, the clinical examination data, the biomarker data and the real-time eye data to obtain multi-modal synchronization data; based on the multi-modal synchronous data, determining a risk evaluation index of the patient with the greater retina aneurysm, and constructing a personalized risk analysis model of the patient with the greater retina aneurysm; creating a risk scoring mechanism for the patient with the greater retinal aneurysm, and setting a health feedback tool for the patient with the greater retinal aneurysm. According to the invention, accurate prediction of the retina great aneurysm can be realized.

The invention belongs to the technical field of medical image segmentation, and relates to an intracranial aneurysm image detection method, system and device and a storage medium. The invention designs a new network architecture, namely a multi-scale axial residual projection network, which is used for improving the accuracy of intracranial aneurysm detection and segmentation. In the aspect of model input, preprocessing steps including matched filtering, Gaussian filtering and Laplacian filtering are adopted for enhancing blood vessel structure and edge information and reducing computing resource requirements. In the aspect of a model structure, multi-scale feature extraction is realized by using a DWR module, and the segmentation capability of the model on a small target is enhanced; besides, the ACRE module is used for enhancing the foreground and inhibiting the background through the axial attention module and the context relation encoder module, and the processing capacity of the network for the edge information of the foreground is improved. According to the invention, the accuracy of intracranial aneurysm detection and segmentation can be improved.

Disclosed are flow diverters including a self-expanding tubular member comprising a plurality of expandable cells having interconnected zig-zag rings and diagonal struts. The tubular member has a constrained configuration having a first outer diameter of at least 1.0 mm sized for delivery using a flow diverter delivery system and an expanded configuration having a second outer diameter larger than the first outer diameter. Related devices, delivery systems, and methods of using the devices and delivery systems for treating disease, particularly intracranial and cerebral aneurysms by deploying implantable expandable devices, are provided.

The invention discloses a carotid artery lumen geometric model construction system based on a CTA image, relates to the technical field of image processing, and comprises a data import module, a volume data cutting module, an interactive carotid artery lumen segmentation module, a 3D model construction module, a model processing module, a model cutting module, a boundary detection module, an entrance and exit filling module, an STL file export module and the like. The modules are clear in division of labor and have detailed working processes. According to the method, the problems that an existing geometric modeling method depends on commercial software, cost is high, legal risks exist, the operation process is tedious, and the speed is low are solved, the carotid artery geometric model can be simply, conveniently, efficiently and accurately constructed, and powerful support is provided for carotid artery fluid dynamics analysis, research and diagnosis of diseases such as atherosclerosis and aneurysm.

A branched graft method includes securing a first end of a branch graft into a first conduit and subsequently moving the second end into a second conduit. The first conduit may be a branch vessel, such as a renal artery and the second conduit may be a main graft that extends over an aortic aneurysm. The branch graft may be deployed starting at an offset distance from the first end, thereby preventing the deployed portion from insertion into the first conduit and predetermining the insertion length into the target vessel. The first end may then be deployed to secure the first end to the first conduit. A branch graft may be a self-expanding stent graft having one or more ripcords, and / or a serpentine ripcord that enables non-linear deployment of the branch graft, or deployment that does not progress from one end to the opposing end.

The present disclosure refers to an in vitro method for diagnosing an aneurysm in a subject, the method comprising determining in an isolated biological sample from the subject the level of one or more microRNAs (miRNA) selected from the group consisting of hsa-miR-223-3p, hsa-miR-199a-3p and hsa-miR-335-5p, wherein, when the level of the one or more miRNAs is lower than a corresponding reference value, this is indicative that the subject suffers from an aneurysm.

The invention relates to the technical field of medical instruments, and provides a drug delivery balloon system for aortic aneurysm, a drug delivery balloon is a hollow balloon, and a blood flow channel for blood to pass through is arranged in the axial extension direction of the drug delivery balloon; the drug delivery balloon comprises a balloon outer surface and a balloon inner surface, wherein the balloon outer surface is provided with micropores for allowing drugs to pass through; the balloon inner surface and the balloon outer surface are correspondingly arranged to form a balloon main body, and a hollow inner cavity of the balloon main body is a blood flow channel; a filling pipeline communicated with the balloon main body is arranged on the peripheral wall of the balloon catheter, and the filling pipeline is used for conveying liquid medicine and / or a contrast agent into the balloon main body so as to fill the balloon main body. By arranging the filling pipeline at the end part of the drug delivery balloon with a hollow structure, the filling work of the balloon main body can be realized. Therefore, when the drug delivery balloon system is used for treating aortic aneurysm, blood vessels are ensured to be unobstructed, blood flow is not blocked, and balloon drug delivery work is completed at the same time.

Devices and methods for treating vascular defects, such as, for example, balloon-type aneurysms, are described herein. In one embodiment, an apparatus includes an insertion portion and an expandable implant. The expandable implant is configured to be deployed in an aneurysm and is coupled to the insertion portion. The expandable implant has a first portion and a second portion coupled to the first portion. The expandable implant is movable between a first configuration in which the first portion and the second portion are substantially linearly aligned and a second configuration in which the second portion at least partially overlaps the first portion.

The invention discloses a method and equipment for training a segmentation model for segmenting an aneurysm, and a storage medium. The method comprises the following steps: acquiring multi-modal image data, wherein the multi-modal image data comprises digital subtraction angiography data, CT angiography data and magnetic resonance angiography data; based on the multi-modal image data, performing blood vessel segmentation and labeling a target aneurysm to obtain a blood vessel segmentation result and a target aneurysm labeling result; constructing a distance map and label data according to the blood vessel segmentation result and the target aneurysm labeling result; and inputting the blood vessel segmentation result, the distance map and the label data into a segmentation model for performing aneurysm segmentation to obtain a target aneurysm, so as to train the segmentation model for segmenting the aneurysm. By using the scheme of the invention, the segmentation precision of the segmentation model can be improved so as to obtain a more accurate target aneurysm.

The disclosure purposes to provide an optical coherence tomography (OCT)-based system for diagnosing a high risk lesion such as a vulnerable atheromatous plaque by using an artificial intelligence model through deep learning. A deep learning-based diagnostic method of diagnosing a high risk lesion of a coronary artery includes: acquiring an OCT image of a coronary artery lesion of a patient; extracting a first feature of a thin cap from the OCT image; setting a region of interest included in the OCT image on a basis of the first feature; and determining whether the region of interest includes a high risk lesion.

The utility model discloses a balloon and an intracranial artery dilatation system. The balloon comprises a balloon body, a plurality of micropores which are formed in the balloon wall of the balloon body and communicated with an inner cavity of the balloon body, and annular protruding parts located on the two sides of the balloon body in the axial direction. After the balloon is expanded, the annular protruding parts make contact with the inner wall of the artery, so that a gap is formed between the balloon wall between the two annular protruding parts and the inner wall of the artery, and medicine flowing out of the micropores enters the gap at first. When the balloon is used, the medicine flowing out of the micropores of the balloon wall of the balloon body enters the gap firstly and does not directly act on the inner wall of the artery, so that the impact of the medicine on the inner wall of the artery can be remarkably reduced, the damage to the artery can be remarkably reduced, and the probability of injury of an inner membrane, aneurysm and acute bleeding can be remarkably reduced.

The utility model relates to the technical field of artery clamps, and provides an aneurysm clamp for neurosurgery, which comprises a clamp main body, the clamp main body comprises a first clamp and a second clamp, lock catch rods are arranged at the same parts of the first clamp and the second clamp, and the first clamp and the second clamp are jointly connected with a spring. According to the aneurysm clamp, due to the arrangement of the buckle and the clamping piece, when a person uses the aneurysm clamp, the clamping piece clamped on the buckle on one side of the first clamp is replaced, the clamping piece is clamped on the buckle on one side of the second clamp, and therefore the aneurysm clamp can be used conveniently. The buckle connecting piece is clamped and fixed according to the buckle groove of the gap between the inclined pieces, and the buckle is extruded through the gap between the connecting piece and the inclined pieces, so that when the first forceps and the second forceps are used for clamping the aneurysm, the first clamping piece and the second clamping piece can be replaced according to the requirement of an operation; therefore, the problems generated in the operation process are solved.

The application discloses an aneurysm segmentation landing zone positioning and identifying method and system based on an optimal blood flow guiding model, and the method comprises the following steps: collecting image data of a target blood vessel region, and pre-processing the image data to obtain a blood vessel enhanced image; performing binaryzation on the blood vessel enhanced image to obtain a blood vessel cavity binary mask; extracting a tree-shaped blood vessel center line from the blood vessel enhanced image by using a blood vessel center line extraction algorithm; analyzing the tree-shaped blood vessel center line to obtain a multi-modal fusion feature vector; predicting a neck aneurysm probability value of the multi-modal fusion feature vector by using a pre-constructed neck aneurysm detection deep learning model, and screening a candidate neck aneurysm region and a parent artery region; and performing membrane membrane on the candidate neck aneurysm region and the parent artery region by using a blood vessel cavity three-dimensional binary mask, and extracting a device anchoring landing zone. According to the scheme, the neck aneurysm precisely positioned by the membrane membrane is taken as a starting point, and an anchoring landing zone section can be accurately screened out by searching upstream and downstream along the parent artery center line.

This application discloses a method and related products for training a generative model for generating three-dimensional aneurysms. The method includes: extracting at least one perspective of two-dimensional image data from original three-dimensional image data; semi-transparentizing the aneurysm-bearing artery region in the two-dimensional image data and marking the centerline of the aneurysm-bearing artery to obtain preprocessed data; extracting aneurysm-related two-dimensional and three-dimensional features using a pre-trained image encoder and shape encoder based on the preprocessed data and the original three-dimensional image data; and training the generative model using the two-dimensional and three-dimensional features as the input and output, respectively, so that the generative model outputs a three-dimensional aneurysm containing the aneurysm-bearing artery region and surrounding vessels. Using the solution of this application, high-precision three-dimensional aneurysm reconstruction can be achieved without original DICOM data, providing a reliable aneurysm-assisted diagnosis and treatment decision-making solution.

Amino-functionalised graphene oxide (GO) for use in the generation of nitric oxide (NO) in vivo. A coating for an implantable medical device comprising amino-functionalised GO, a coated implantable me

A device for treating an aneurysm in a blood vessel includes an occlusive element arranged on a wire, the occlusive element including a cover for covering the neck of the aneurysm and an internal anchoring member. The cover is configured to expand from a compressed structure in the tube to an expanded structure to cover the neck of the aneurysm when pushed out from the distal end of the tube. The cover includes a sphere of mesh material formed as a hemisphere, the hemisphere including two layers of mesh formed by folding the top of the sphere into the bottom of the sphere. The internal anchoring member is connected to a second surface of the cover and extends from the second surface of the cover, and is configured to contact the inner surface of the aneurysm. The internal anchoring member can be a cylindrical rod extending from a central portion of the cover.

To provide an intra-aneurysmal occlusion device to be deployed into the aneurysm sac for providing aneurysm treatment and / or amelioration through the creation of blood flow disruption and ultimate stasis.SOLUTION: Provided herein is an occlusion device for implantation into a body lumen or aneurysm, comprising a continuous compressible mesh structure comprising axial mesh carriages 20 configured end to end, where each end of each carriage is a pinch point in the continuous mesh structure. Also provided herein is a kit comprising the occlusion device disclosed herein and means for delivery thereof. Methods of manufacture and use of the occlusion device are also disclosed.SELECTED DRAWING: Figure 1B