176 results about "Artery aneurysm" patented technology

A device for in situ treatment of vascular or cerebral aneurysms comprises an occlusion device having a flexible, longitudinally extending elastomeric matrix member that assumes a non-linear shape to conformally fill a targeted site. The occlusion device comprises a flexible, longitudinally extending elastomeric matrix member, wherein the device assumes a non-linear shape capable of fully, substantially, or partially conformally filling a targeted vascular site. In one embodiment the vascular occlusion device comprises a first longitudinally extending structural element having a longitudinally extending lumen and an outer surface; a second longitudinally extending structural element extending through the lumen; and an elastomeric matrix member surrounding the outer surface, wherein the second structural member does not engage or attach to the first structural element or the elastomeric matrix.

Described herein are vascular remodeling devices that include a proximal section, an intermediate section, and a distal section. During deployment, the proximal section can expand from a compressed delivery state to an expanded state and anchors the device in an afferent vessel of a bifurcation. The distal section expands from the compressed delivery state to an expanded state that may be substantially planar, approximately semi-spherical, umbrella shaped, or reverse umbrella shaped. The distal section is positioned in a bifurcation junction across the neck of an aneurysm or within an aneurysm. The intermediate section allows perfusion to efferent vessels. Before or after the device is in position, embolic material may be used to treat the aneurysm. The distal section can act as a scaffolding to prevent herniation of the embolic material. The device can be used for clot retrieval with integral distal embolic protection.

The self-expandable endovascular apparatus for aneurysm occlusion of the invention comprises a deformable shape memory frame with at least a partial segment covering comprised of a matrix implant material. The device can be folded and/or stretched to adopt a narrow profile for loading into a coaxial delivery device and expands in place as it adopts its original shape on release from the device into an aneurysm. A method of treating an aneurysm, comprises the steps of: (a) providing the self-expandable endovascular apparatus inserted into a lumen of a delivery device comprising a proximal end and a distal end, the distal end having a distal tip; (b) advancing the distal tip of the delivery device into an opening in an aneurysm having an interior sac; (c) advancing the apparatus through the lumen into the opening; and (d) withdrawing the delivery device, whereby the apparatus expands into the sac and covers the opening.

Provided herein is an occlusion device for intrasaccular implantation and/or vascular occlusion comprising: (a) a substantially solid marker having a proximal end, and a distal end; and (b) a low profile resilient mesh body attached to the distal end of the marker, the body having a delivery shape and a deployed shape capable of conforming to aneurysm walls; wherein the body has a diameter greater than a diameter of an aneurysm to be treated. Also provided herein is a kit comprising the occlusion device disclosed herein and a means for delivery thereof. Methods of manufacture and use of the occlusion device disclosed herein are also disclosed.

A system for treating an aneurysmatic abdominal aorta, comprising (a) an extra-vascular wrapping (EVW) comprising (i) at least one medical textile member adapted to at least partially encircle a segment of aorta in proximity to the renal arteries, and (ii) a structural member, wherein EVW is adapted for laparoscopic delivery, and (b) an endovascular stent-graft (ESG) comprising (i) a compressible structural member, and (ii) a substantially fluid impervious fluid flow guide (FFG) attached thereto. Also described is an extra-vascular ring (EVR) adapted to encircle the neck of an aortic aneurysm. Further described are methods for treating an abdominal aortic aneurysm, comprising laparoscopically delivering the extra-vascular wrapping (EVW) and endovascularly placing an endovascular stent-graft (ESG). Also described are methods to treat a type I endoleak.

Provided herein is a copolymer that includes a soft block (A) that contains poly(ester amide) (PEA) and a hard block (B). The copolymer can be any of AB, ABA or BAB type block copolymers. By varying the relative amount of the PEA block and the hard block, one can obtain a copolymer with a T_g for mechanical integrity in drug-delivery stent applications. The copolymer can be used alone or optionally in combination with a biobeneficial material and/or a biocompatible polymer to form an implantable device or a coating on an implantable device. When the copolymer is used in combination with a biobeneficial material, the copolymer and the biobeneficial material can be co-deposited or applied in sequence during the coating process. A coating formed of the copolymer may also include a bioactive agent. The implantable device can be implanted in a patient to treat, prevent, or ameliorate a disorder such as atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, and/or tumor obstruction.

The invention discloses a covered stent for an aortic dissection surgery, a delivery device and a use method thereof. The stent comprises a main body, wherein the main body decreases progressively from the heart near end with a large diameter to a far end with a small diameter, and the superior border of the middle piece of the main body is a rotary island; a tectorial membrane is arranged except the rotary island, and the two ends of the main body and the rotary island are provided with positioning marks. The delivery device comprises a delivery sheathing canal, a suture and a traction guide wire, wherein the suture is sewn on the outer side surface of the covered stent, and the two side edges of the covered stent at the near end of the left subclavian artery are sewn up by the suture; the stent is closed up to be in a semi-contraction state by the traction guide wire through the suture, and the covered stent is closed up and wrapped in the delivery sheathing canal; the delivery sheathing canal is provided with a steeple, and the far end of the traction guide wire penetrates through the handle of the delivery sheathing canal and is fixed. The covered stent for the aortic dissection surgery is used for a dissecting aneurysm surgery of the lesser curvature side of aortic arch and an interventional minimally invasive surgery of an aortic dissection near the brachiocephalic trunk, so that the trauma of a thoracotomy is avoided, and the athe lumen crevasse occlusion is directly implemented.

Described is a low voltage, pulsed electrical stimulation device for controlling expression of, for example, follistatin, a muscle formation promotion protein, by tissues. Epicardial stimulation is especially useful for heart treatment. Follistatin controlled release is also useful for treating other ailments, such as erectile dysfunction, aortic aneurysm, and failing heart valves.

The invention discloses a cerebral aneurysm hemodynamic index evaluation method, system and device and a medium. The evaluation method comprises the following steps: acquiring human body cerebral artery image data; carrying out anatomical modeling on the human body cerebral artery medical image data to obtain a cerebral aneurysm anatomical model; fluid mechanics calculation processing is conductedon the cerebral aneurysm anatomical model, and outputting a calculation result; and adding the calculation result to a corresponding position of the cerebral aneurysm anatomical model, and carrying out visual display of hemodynamic indexes. According to the method, the system, the equipment and the medium, the hemodynamic indexes of the cerebral aneurysm can be obtained according to the medical image data of the human cerebral artery. Therefore, the relationship between the hemodynamic characteristics and the occurrence, development and rupture of the aneurysm can be analyzed based on the obtained hemodynamic indexes, and a theoretical basis is provided for risk factor assessment and interventional therapy of the cerebral aneurysm.

An aneurysm embolization device includes at least: a sac-shaped balloon dome part which is inserted into the aneurysm, then expanded and left therein; and a balloon plane part which is provided at an opening of the balloon dome part and covers a mouth part of the aneurysm. The balloon plane part has a hole communicating with the inside of the balloon dome part. The aneurysm embolization device thus constituted is housed into a lumen of a protective outer sheath member formed of a flexible elongated-body having the lumen therein. A tip part of the protective outer sheath member is placed at a desired position, and the aneurysm embolization device is ejected from the tip part of the protective outer sheath member. The aneurysm embolization device thus ejected includes the balloon dome part placed at a desired position and the balloon plane part deploying to cover the desired position.

The invention discloses an individual aneurysm model obtained through 3D printing technology and a manufacturing method thereof. The manufacturing method comprises the steps of firstly, performing high-precision layered scanning on an artery of an aneurysm patient by means of imaging equipment, thereby aneurysm image data; then performing sorting by means of inverse reconstruction software for obtaining the artery, and performing three-dimensional reconstruction; performing expansion amplification on the reconstructed artery by means of computer-aided 3D design software, then subtracting original blood vessels through Boolean operation, obtaining an empty aneurysm model and outputting a 3D printing identifiable file; and finally printing the aneurysm model by means of different materials through a 3D printer, wherein the size ratio between the aneurysm model and the aneurysm of the patient is 1:1. The aneurysm model obtained through the method can settle a defect of disease model shortage in China and can be applied in the fields of disease teaching, open heart surgery or interventional surgery training, surgery planning, etc. The aneurysm model and the manufacturing method have advantages of user-friendly customization, high accuracy, effective realizing of visuality and touchness, simple process, high forming speed and low cost.

Apparatus (10) is provided that includes an extra-vascular ring (12) and an endo vascular stent-graft (14). The ring (12) comprises a structural member (30), which is configured to assume an elongate hollow shape (32), which has first and second longitudinal ends (40, 42), and is suitable for placement at least partially around an aorta (20) so as to provide a generally cylindrical landing zone. The endovascular stent-graft (14) is suitable for endovascular placement inside the aorta (20) such that a portion of the stent-graft (14) is positioned against an internal wall of the aorta (20) at the landing zone provided by the structural member (30). If the structural member (30) is unrolled to a planar shape (82), one side (90) of the planar shape (82) is defined by the first longitudinal end (40), and at least the first longitudinal end (40) has a profile that defines a series of curved portions and has no singularities or discontinuities, which profile extends along at least 50% of the first longitudinal end (40).

The invention belongs to the field, particularly relates to a catheter detection method for a vascular aneurysm interventional operation navigation system, and aims to solve the problem that an interventional catheter in an X-ray transmission image in an intravascular aneurysm repair operation cannot be accurately segmented and tracked in real time. The method comprises the following steps: acquiring an X-ray transmission video sequence of a region containing a catheter as a to-be-detected sequence, generating a segmentation mask sequence through a trained encoding and decoding structure according to the to-be-detected sequence, and covering the to-be-detected video with a binary segmentation mask sequence to obtain a video sequence of the catheter. The accuracy and speed of segmentation and tracking of the X-ray transmission image interventional catheter in the intravascular aneurysm repair operation are improved, and the real-time performance required by an operation tracking algorithm is met.

The invention belongs to the field of medical image processing. The invention discloses an intracranial aneurysm detection method and system based on a convolutional neural network. The detection method is based on a three-dimensional time leap magnetic resonance angiography image (3D Time-of-Flight MR Angiography, 3D TOF MRA), and is characterized in that first of all, blood vessels are extracted, a series of cubic voxel blocks are extracted as ROIs (Region of Interest) along the central line of the blood vessel; maximum density projection is performed on each ROI (Region of Interest) in a plurality of directions to obtain a MIP (Maximal Intensity Projection) by taking the MIP as the ROI; the MIP graph is used as input, the trained convolutional neural network is used for classifying theMIP graph, an obtained classification result reflects whether the ROI contains the aneurysm or not, and then whether the intracranial aneurysm exists in the to-be-detected object or not is judged. According to the method and the system, the whole process of the method is processed, and the setting mode of each functional module component in the corresponding system device is improved, so that thedetection method and the detection system have relatively high classification accuracy and sensitivity.

The invention provides an intracranial aneurysm virtual stent diagnosis and treatment system and a method thereof. The system comprises a preoperative vascular model and virtual stent initialization model acquisition module which is used for three-dimensional vascular model reconstruction and model smoothing, automatic centerline extraction, and stent model initialization, a virtual stent algorithm execution module which is used for simplex mesh conversion of a virtual stent and preoperative vascular model, virtual stent deployment, vascular wall contact detection and force balance determination, and a surgical plan evaluation module which uses morphological parameters and hemodynamic function parameters to evaluate the effectiveness of a surgical plan developed by a doctor before a surgery. According to the invention, a virtual stent technology based on Simplex mesh is used to simulate the deployment and placement of a stent in an intracranial artery, which ensures the deployment speed of the virtual stent on the basis of ensuring accuracy; the intracranial aneurysm virtual stent diagnosis and treatment system with timeliness and accuracy is built; and guidance is provided for thepreoperative plan planning of intracranial aneurysms.

Methods and systems for controlling aneurysm initiation or formation in an individual are presented; the technique comprises receiving morphological data of an artery being indicative of at least first and second geometrical parameters of the artery along its trajectory; analyzing the data to identify at least one flow-diverting location along the artery satisfying first and second predetermined conditions of the geometrical parameters; classifying the individual as having or not having disposition for future formation of an aneurysm, depending respectively on whether the at least one flow-diverting location is identified or not and generating classification data; and generating prediction data for the individual with regard to future aneurysm formation.