6 results about "Internal capsule" patented technology

This invention relates to the field of natural language processing technology, specifically to a triage method and system for neurological diseases, comprising the following steps: segmenting the syntactic structure of the patient's chief complaint text sequence and identifying nodes; calculating and quantifying the nesting degree of the patient's linguistic organization logic; and obtaining a syntactic potential depth value. This invention can filter out noise interference from complex clinical expressions and extract neurological syndrome features by comparing them with a preset internal capsule lesion pattern. By jointly analyzing feature tensors pointing to limb paralysis with syntactic potential depth values ​​below the normal threshold, dual cross-validation of somatic motor disorders and central cognitive impairment is achieved. Furthermore, by comparing with feature thresholds of peripheral nerve or spinal cord lesions, the specificity of identifying central acute and severe illnesses such as ischemic stroke is improved, optimizing the accuracy of emergency triage.

Provided herein are targeting peptides and vectors containing a sequence that encodes the targeting peptides that deliver agents to specific substructures in the brain. Specifically, the targeting peptide is a component of a modified, sequence-specified adeno-associated virus (AAV) capsid protein further wherein the brain substructure may be the globus pallidus, putamen, internal capsule, caudate, claustrum, substantial nigra, motor cortex, insula,.temporal cortex, thalamus, hippocampus, subiculum, and deep cerebellar nuclei.

The application relates to the medical technical field, in particular to an interventional radio frequency coil and a use method thereof. The interventional radio frequency coil comprises a multi-cavity catheter, a line channel, an inner balloon channel, an outer balloon channel and a endoscope channel are arranged in the multi-cavity catheter; an inner balloon is arranged on the surface of the multi-cavity catheter, the inner balloon is communicated with the inner balloon channel, and the inflation state of the inner balloon is adjusted through the inner balloon channel; a coil main body is arranged on the outer surface of the inner balloon, the shape of the coil main body can be adjusted through the inflation or pressure relief of the inner balloon, and the line of the coil main body is led out through the line channel; an outer balloon is arranged on the surface of the multi-cavity catheter and located outside the inner balloon and the coil main body; the inflation state of the outer balloon can be adjusted through the outer balloon channel, wherein: the outer balloon tightly holds the coil main body when pressure relief; when the outer balloon is inflated, surrounding tissues can be expanded to separate the coil main body from the tissues. The scheme is used to realize high signal-to-noise ratio and high resolution imaging of deep tissues or cavities in magnetic resonance.

A method is provided for treating neurogenic anorexia nervosa in a subject in need thereof, using a magnetic resonance guided focused ultrasound treatment system. The method comprises applying high-intensity focused ultrasound energy to multiple treatment target points on the bilateral anterior limbs of the left and right internal capsules of the subject to regulate the bilateral anterior limbs of the subject; and inducing normalization of weight in the subject.

A method is provided for treating neurogenic anorexia nervosa in a subject in need thereof, using a magnetic resonance guided focused ultrasound treatment system. The method comprises applying high-intensity focused ultrasound energy to multiple treatment target points on the bilateral anterior limbs of the left and right internal capsules of the subject to regulate the bilateral anterior limbs of the subject; and inducing normalization of weight in the subject.

The present invention relates to a method for producing a nonhuman primate animal model of cerebral infarction, comprising administering endothelin to basal ganglia and thalamic region of a nonhuman primate, and thereby inducing basal ganglia damage, thalamus damage, and internal capsule damage; and a pharmaceutical composition for the treatment of cerebral infarction at a subacute to chronic stage, penetrating branch infarction, or cerebral infarction having brain damage in a penetrating branch territory, comprising a NeuroD1 protein or a polynucleotide encoding the NeuroD1 protein.