The invention discloses a cloud computing-based monitoring management system, which comprises N monitored server clusters, a monitoring management server and a management client. The monitoring management system for cloud computing adopts the cluster system in a cloud computing environment for monitoring, the N monitored server clusters are connected with the monitoring management server, the monitoring management server is connected with the management client, the N monitored server clusters comprise multiple sub clusters comprising a certain number of servers, servers in each sub cluster can have different quantities and scales possibly, and the monitoring management server is in charge of monitoring and management operation on the clusters in the system. According to the cloud computing-based monitoring management system, the structure is reasonable, the use is convenient, the monitoring system adopts a distributed monitoring management structure, the clusters are divided into multiple blocks, each block is charged by a set of monitoring subsystem for acquisition of performance monitoring data, load balance of the monitoring system is realized, and scale expansion of the monitoring system is facilitated.