21 results about "False Aneurysms" patented technology

The invention discloses an intracranial aneurysm detection method and device based on a bottom double-branch network and confidence coefficient calibration, and the method comprises the steps: carrying out the low-dimensional feature extraction of an image in the bottom double-branch network, and obtaining a feature map, dividing the feature map into a first sub-feature map and a second sub-feature map, and performing feature extraction and fusion through different convolution operation branches to obtain a final feature map; performing prediction and matching of a real bounding box through an optimal transmission algorithm, and training a bottom double-branch network according to a matching result; in the bottom double-branch network training process, confidence coefficient calibration is carried out at the output end of the model by constructing a loss function based on confidence coefficient scores, and finally the trained bottom double-branch network is obtained to serve as an intracranial aneurysm detection model; and inputting the new to-be-detected picture into the intracranial aneurysm detection model, and detecting to obtain a high-confidence-coefficient intracranial aneurysm prediction bounding box so as to accurately position the intracranial aneurysm. According to the invention, the accuracy and reliability of intracranial aneurysm detection can be obviously improved.

A medical device is disclosed and may have a spiral shape structure that can function as a stent, such as a flow diversion stent to treat aneurysms. The medical device may have a spiral shape structure that can function as an occlusive device, for instance to occlude aneurysms. The medical device may include a shape setting structure to selectively adjust the shape of the medical device.

Medical set (2) for the treatment of aneurysms (4) with a main catheter (8), a covering device (12) which can be moved through the main catheter (8) to a treatment site (10) for covering an aneurysm (4), wherein the covering device (12) is connected or connectable to a transport wire (15) and comprises a self-expanding lattice structure (14) made of webs (16) which are integrally connected to one another and delimit inner cells (18) and edge cells (20), wherein the edge cells (20) form a closed edge cell ring (24) at a longitudinal end (22) of the lattice structure (14), which is connected to inner cells (18) only on one side, characterized in that the lattice structure (14) is provided with a cover (26) made of an electrospun fabric which has irregularly large pores (28), wherein the cover (26) has an area of 100,000 µm 2 at least 10 pores (28) having a size of at least 15 µm 2and wherein a plurality of inner cells (18) of the lattice structure (14) which are immediately adjacent in the circumferential direction of the lattice structure (14), in particular all inner cells (18) of an inner cell ring, are free of covering, wherein the cover-free inner cells (18) are cut free by means of a cutting tool by guiding the cutting tool along the webs of the inner cells (18) to be cut free.

To provide a screening method for prevention and / or treatment of aneurysm or rupture of aneurysm resulting from excessive release of calcium ions from the endoplasmic reticulum into the cytoplasm, as well as a fusion gene to be used therein.SOLUTION: A screening method introduces into cultured cells having an endogenous GON domain with a sequence different from that of an exogenous GON domain, a fusion gene comprising a KillerRed protein gene and a GON domain protein gene.SELECTED DRAWING: None

The present invention provides a closure device and a closure device, the closure device comprising: two ends, at least two supporting structures and a coating; the two ends are arranged at the two ends of the closure device along the axial direction; at least two supporting structures are arranged circumferentially around the axis of the closure device, and the two ends of at least two supporting structures respectively converge at one end; the supporting structure switches between an expanded state and a contracted state; when the supporting structure is in the expanded state, the supporting structure protrudes outward along the radial direction of the closure device; the coating is coated on the outside of at least two supporting structures and is used to contract or expand as the state of the supporting structure changes. With such a configuration, the closure device has low dependence on the doctor's skills, high treatment efficiency, simple operation, low surgical cost, no need for long-term dual-antibody administration, and can also achieve non-directional closure, and can treat apical aneurysms and sidewall aneurysms.

The utility model discloses an iatrogenic pseudoaneurysm compression hemostasis bandage capable of being used for ultrasonic exploration, and relates to the technical field of medical instruments, in particular to a compression hemostasis bandage. Comprising a hard fixing plate and straps tied to the two ends of the fixing plate, a probing opening for an ultrasonic probe is formed in the fixing plate, a box body is arranged on the surface, facing a probed body, of the probing opening, and a cavity formed by the box body and the probing opening can contain a part or the whole of the ultrasonic probe. And the bottom surface of the box body is made of a hard material suitable for penetration of ultrasonic waves. According to the technical scheme, the compression point can be accurately calibrated, compression is carried out on the compression point to achieve tumor hemostasis, and binding can be carried out in time to obtain the best compression hemostasis effect.

Treatment of aneurysms can be improved by delivering an occlusive member (e.g., an expandable braid) to an aneurysm sac in conjunction with an embolic element (e.g., coils, embolic material). A treatment system for such treatment can include an electrolytically corrodible core wire having a proximal portion, a distal portion, and a detachment zone between the proximal portion and the distal portion. An occlusive member having a proximal hub is coupled to the core wire distal portion. A conduit extends along at least a portion of the core wire. The conduit has a lumen configured to pass an embolic element therethrough.

The present invention discloses a coil, belonging to the technical field of medical devices. The coil includes a coil body, and the coil body includes a support part and a filling part. The support part has a shape memory effect and can adapt to the shape of the opening of the aneurysm sac and support at the neck of the aneurysm sac when expanded; a part of the support part is made of a degradable material, and the other part is made of a non-degradable material; the filling part is filled inside the aneurysm sac, and the filling part is made of a degradable material. The coil of the present invention can reduce the mass effect and can be stably implanted into the aneurysm sac.

The utility model discloses an aortic cannula, and relates to the technical field of aortic cannulas. Comprising a cannula body, a first positioning airbag, a second positioning airbag and a connecting hose. The first positioning air bag and the second positioning air bag are arranged on the outer side of the cannula body and can be tightly pressed on the inner side and the outer side of an aorta adventitia respectively during use, and the problems that high-pressure blood flow enters an aorta cavity, and aorta dissection or false aneurysm is formed are solved; meanwhile, when the intubation tube body needs to be separated from extracorporeal circulation for tube drawing operation, air in the second positioning air bag is completely discharged, then the intubation tube body is pulled out, the first positioning air bag can play a role in blocking sprayed blood flow, and the operator can be effectively protected; the problems that in a traditional aortic cannula, the aortic wall structure is prone to being damaged in the cannula inserting process, and false aneurysm or aortic dissection is formed are solved; the blood pressure in the aorta blood vessel is high, the purse string is easy to avulsion, the aorta wall is damaged, and the intubation tube is easy to fall off.

Treatment of aneurysms can be improved by delivering an occlusive member (e.g., an expandable braid) to an aneurysm sac in conjunction with an embolic element (e.g., coils, embolic material). A treatment system for such treatment can include an electrolytically corrodible core wire having a proximal portion, a distal portion, and a detachment zone between the proximal portion and the distal portion. An occlusive member having a proximal hub is coupled to the core wire distal portion. A conduit extends along at least a portion of the core wire. The conduit has a lumen configured to pass an embolic element therethrough.

To provide a system and a method capable of treating an aneurysm even when the aneurysm is relatively small.SOLUTION: A system 10 has an implant body 20 and a joint part 30. The implant body includes a ring-shaped skeleton part 50 having a self-expanding force, and can expand or contract in a radial direction. In the joint part, the implant body in an expanded state of being deployed in an aneurysm 100 is joined to an aneurysm wall 101. The skeleton part includes: a ring-shaped body part 51; and an anchor part 52 extending from the body part to the radially outside and inserted to the aneurysm wall. The anchor part functions as the joint part.SELECTED DRAWING: Figure 1

The utility model relates to the technical field of medical auxiliary instruments, in particular to a special needling instrument for pseudoaneurysm sclerotherapy, which is characterized in that a plugging structure is mounted on a support structure, a needle core I extends into the support structure, one end of the needle core I extends out of one end of the support structure, and the needle core I and the support structure are punctured into the body of a patient. The first needle core is pulled out, the plugging structure is supported through the supporting structure, the plugging structure is unfolded, the near-end blood vessel of the pseudoaneurysm is blocked, and then a doctor injects thrombin into the pseudoaneurysm, so that the practicability of the special needle for sclerotherapy of the pseudoaneurysm is improved; comprising a first needle core; the device further comprises a supporting structure and a plugging structure, the first needle core is sleeved with the supporting structure, and the plugging structure is installed on the supporting structure. The first needle core is matched with the supporting structure to penetrate into the body of a patient, and the supporting structure is matched with the blocking structure to block near-end blood vessels of pseudoaneurysm.

Liquid compositions comprising nimodipine having improved nimodipine concentrations are provided herein. Methods of improving neurological outcome by reducing the incidence and severity of ischemic deficits in patients with subarachnoid hemorrhage from ruptured intracranial berry aneurysms with the liquid compositions of the present invention are also detailed herein.

The invention relates to the technical field of medical instruments, and discloses a pseudoaneurysm treatment device which comprises a trocar system and an injection needle. The trocar system comprises a cannula, a puncture needle, a plugging needle and a blunt needle, and the puncture needle, the plugging needle and the blunt needle can move in the cannula; the front end of the puncture needle is a sharp head; a balloon is arranged at the front end of the plugging needle body; the front end of the blunt needle is blunt and is used for smearing thrombin; the injection needle is used for injecting thrombin into the pseudoaneurysm. The trocar system is used for achieving puncture and blocking and blood coagulation of the joint of the pseudoaneurysm and the artery, thrombin is injected into the pseudoaneurysm through the injection needle, the blood coagulation area can be limited in the pseudoaneurysm, and the reliability of pseudoaneurysm treatment is improved.

Liquid compositions comprising nimodipine having improved nimodipine concentrations are provided herein. Methods of improving neurological outcome by reducing the incidence and severity of ischemic deficits in patients with subarachnoid hemorrhage from ruptured intracranial berry aneurysms with the liquid compositions of the present invention are also detailed herein.

A virtual angiogram can be performed by simulating transport of contrast agent through a model of a portion of a vasculature of a patient. The simulation can be based on a patient-specific pulsatile flow velocity field of the vasculature portion. At least one contrast retention metric for an aneurysm in the vasculature portion can be determined based on the virtual angiogram. The contrast retention metric can be indicative of flow stagnation in the aneurysm. In some aspects, the aneurysm can be identified as unstable based at least in part on the at least one contrast retention metric. Responsive to the identification, a treatment can be administered for the aneurysm even though it has not yet ruptured. Alternatively or additionally, the aneurysm can be identified as ruptured, for example, to discriminate between multiple potentially-ruptured aneurysms in the patient for treatment.

The invention relates to a medical kit for treating a vascular malformation, in particular an aneurysm and / or a fistula, having a durable implantable covering device (12), in particular a stent, for covering the vascular malformation, wherein the covering device (12) has a tubular, self-expandable mesh structure (14) and a covering (20) made of an electrospun fabric, wherein the covering (20) is connected to the mesh structure (14) and at least partially covers the mesh structure (14) in order to be placed over the vascular malformation in an implanted state, and an embolization medium (40) which can be applied for treating the vascular malformation in the implanted state by means of a delivery device (44), wherein the covering (20) forms a porous membrane which can be penetrated by the delivery device (44) for applying the embolization medium (40) and is adapted to lie against the outer circumference of the delivery device (44) in a penetrated state.

The invention relates to a one-component medical composition in the form of a hydrogel which comprises silicate nanoparticles, water, a hydrogel-forming synthetic polymer and one or more bio-based proteins and / or polymers. Such a composition can be used as a flexible substitute for coil implants in the treatment of aneurysms, tumours or arteriovenous malformations, and due to its extensive biodegradability and improved tolerability, makes long-term anticoagulation therapy unnecessary. The present invention also relates to devices filled with such a composition, and kits which contain such compositions or devices as one component and a medical device, in particular in the form of a stent, as another component.

The invention provides medical glue for treating aneurysm and a preparation method of the medical glue, and the medical glue comprises the following components in parts by weight: 55-61 parts of n-octyl cyanoacrylate; 4 parts of a polymerization inhibitor; 3.3-5 parts of a first stabilizer; 5-8 parts of a second stabilizer; 15-22 parts of a plasticizer; 2.6 to 4.8 parts of a first thickening agent; 0.2 to 0.3 part of a second thickening agent; 4-5 parts of a bonding strength modifier; the first thickening agent is one or two of polyisobutyl methacrylate or cellulose acetate butyrate, and the second thickening agent is calixarene. The medical glue provided by the invention has the characteristics of high viscosity, high curing speed, good flexibility and long degradation period, and is suitable for blocking aneurysm.

The embodiment of the utility model relates to a degradable embolism device. The degradable embolism device comprises a skeleton main body, hydrogel, a butt joint sleeve, a connecting line, a first bonding point and a second bonding point, wherein the skeleton main body is of a woven structure, and hydrogel is borne in the skeleton main body; two ends of the hydrogel are respectively fixed with two ends of the skeleton main body; the butt joint sleeve is connected with the far end of the skeleton main body; the plug device is connected with the external conveying rod through the connecting line; the far end of the skeleton main body and the far end of the hydrogel are bonded and fixed through the first bonding point; and the near end of the skeleton main body, the near end of the hydrogel, the butt-joint sleeve and the connecting line are bonded and fixed through the second bonding points. The degradable embolism device has high flexibility and can be formed in an aneurysm cavity in a self-adaptive mode; and in addition, the implant has the characteristic of being completely degradable, so that the implant can be completely degraded and absorbed by human tissues or discharged out of the body after the aneurysm is normally healed.

A method for manufacturing a tray 44 for storing aneurysm clips is disclosed, in which a metal plate 2 is first provided, which is then provided with perforations 4. The perforations 4 are produced by laser cutting, and the plate 2 provided with the perforations 4 is formed by bending into a corrugated or trapezoidal sheet 24, which has at least one trough-shaped recess 22 for storing aneurysm clips. Furthermore, a tray 44 for storing aneurysm clips is disclosed, which has a corrugated or trapezoidal sheet 24 provided with laser-cut perforations 4, wherein the corrugated or trapezoidal sheet 24 has at least one trough-shaped recess 22.