System and method for predicting physical properties of an aneurysm from a three-dimensional model thereof

A technology of aneurysm and material properties, applied in medical simulation, electrical digital data processing, diagnostic recording/measurement, etc., can solve problems such as death, aneurysm rupture, intracranial hemorrhage, etc.

Inactive Publication Date: 2007-11-28
KONINKLIJKE PHILIPS ELECTRONICS NV
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  • Abstract
  • Description
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Problems solved by technology

The most serious outcome, especially if the patient's blood pressure is elevated, is rupture of the aneurysm leading to intracranial hemorrhage and possibly death
Mechanisms of aneurysm origin, growth, and rupture are currently not well understood

Method used

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  • System and method for predicting physical properties of an aneurysm from a three-dimensional model thereof
  • System and method for predicting physical properties of an aneurysm from a three-dimensional model thereof
  • System and method for predicting physical properties of an aneurysm from a three-dimensional model thereof

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Embodiment Construction

[0024] The present invention basically relates to situations where weakening of the vessel wall is the main cause of aneurysm formation. The systems of the present invention are generally arranged and constructed to obtain physical models and perform numerical simulations based on advanced property theory for the purpose of predicting the mechanical and geometric quantities involved in the formation of, for example, cerebral saccular aneurysms.

[0025] In the first case, it has been established through numerical simulations of aneurysm formation using finite element software packages such as Mart / Mentat 2000 that the neck-like geometry of saccular aneurysms can be explained by exploiting the distribution of mechanical properties, such that this geometry is elastically weak at its center, but also substantially as stiff as the parent vessel near its boundaries, as can be seen from Figure 1, which shows the For aneurysms, this finite element method (FEM) accounts for the total ...

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Abstract

A three-dimensional rotational angiography (3DRA) system, in which a finite element method (FEM) package is incorporated which can read in suface meshes (20b) of a reconstructed 3DRA image of an aneurysm to generate FEM meshes (20a) which are closely approximated to the observed aneurysm (20b) in an iterative process by changing the material properties of the aneurysm used in generating the simulated representations (20a) thereof. Thus, the material properties of the closely approximated simulated representation (20a) can be used in subsequent analysis of the physical properties of the aneurysm under consideration.

Description

technical field [0001] The present invention generally relates to systems and methods for predicting physical properties of an aneurysm from a three-dimensional model of the aneurysm. Background technique [0002] Cerebral aneurysms are pathological dilations of cerebral arteries, often occurring near arterial bifurcations in the Willis Circle, and are usually caused by a weakened vessel wall. The most serious outcome, especially if the patient's blood pressure is elevated, is rupture of the aneurysm leading to intracranial hemorrhage and possibly death. The mechanisms of aneurysm origin, growth, and rupture are currently not well understood. [0003] Three-dimensional rotational angiography (3DRA) is a relatively new technique for imaging blood vessels in humans. The reconstructed 3D high-resolution images generated from rotational digital subtraction angiography data allow for potentially interesting quantitative studies. Digital subtraction angiography (DSA) is the sta...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B6/00G06F19/00A61B5/107
CPCA61B5/02014A61B6/466G06F19/3437A61B5/1076A61B6/504G16H50/50
Inventor P·M·J·龙根R·苏尔蒙德R·P·J·赫曼斯
Owner KONINKLIJKE PHILIPS ELECTRONICS NV
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