A super-flexible nickel-titanium alloy intracranial stent with micro-nano structure

Abstract

The invention relates to a super-compliant nickel-titanium alloy intracranial vascular stent with a micro-nano structure, which can be used to assist coil embolization in the treatment of intracranial aneurysms, and belongs to the field of medical devices. The main body of the intracranial vascular stent is composed of an open-loop structure and a closed-loop structure. The open-loop structure is formed by connecting the first V-shaped unit arranged in the circumferential direction with the second V-shaped unit arranged in the circumferential direction through connecting rods. The closed-loop structure consists of The second V-shaped units arranged in the circumferential direction are connected by connecting rods, and the ratio of the open-loop free ends of the second V-shaped units to the open-loop free ends of the first V-shaped units is 1:2; the open-loop structure enhances the flexibility of the bracket And adherent, closed-loop construction provides supportive performance. The intracranial vascular stent of the present invention has super-flexible performance, and can be used for assisting coil embolization in the treatment of aneurysms in complex intracranial vessels (such as large-curvature vessels and variable-diameter vessels), achieving good wall-attachment effects.

Description

technical field [0001] The invention relates to a super-compliant nickel-titanium alloy intracranial vascular stent with a micro-nano structure, which can be used to assist coil embolization in the treatment of intracranial aneurysms, and belongs to the field of medical devices. Background technique [0002] Intracranial aneurysm is the abnormal bulging of the intracranial artery wall due to congenital abnormal defects of blood vessels or acquired lesion trauma and other factors, and is the primary cause of subarachnoid hemorrhage. Compared with aneurysm clipping and ligation, endovascular interventional therapy is safer and more adaptable. It is currently the main intracranial aneurysm treatment method. Aneurysm occlusion can be achieved by intracranial vascular stent-assisted coil embolization . [0003] However, intracranial blood vessels are tortuous and complex, and intracranial aneurysms are more likely to occur at the bifurcation of the arterial ring at the base of t...

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Problems solved by technology

[0003] However, intracranial blood vessels are tortuous and complex, and intracranial aneurysms are more likely to occur at the bifurcation of the cerebral base arterial ring and its main branches, and there are often different degrees of curvature, and the diameter of the blood vessels may also be inconsistent

In addition, the size of intracranial aneurysms varies greatly, and interventional treatment for some wide-necked and fusiform aneurysms is still very difficult

For existing products, intracranial stent structures are roughly divided into two types: open-loop and closed-loop. Each structural stent has its own advantages and disadvantages. For blood vessels with high curvature, the bending performance of open-loop stents is better than that of closed-loop stents. Avoid discounting, ovalization, etc. Since the stent is not connected to the connecting rod in the open-loop part, the stent has better adaptability to uneven blood vessels, but the outer gap will increase with the curvature, resulting in the risk of the coil coming out; In addition, for open-loop structural stents with long unit spans, the open-loop part may cause non-adherence or protrude into the aneurysm, causing thrombosis and other problems

Although the closed-loop structure stent can provide high support performance, due to its overall continuity and high rigidity, the stent is relatively hard as a whole, and the wall-attachment is poor after implantation, and even displacement occurs, eventually causing complications such as thrombosis and restenosis

[0004] Most of the existing products are designed with a unified structure. For complex intracranial vessels, especially those with large curvature and variable vessel diameters, there is little coordination between compliance / adherence and support performance, and it is difficult to over-embolize coils. The wide-necked, fusiform aneurysm neck provides local support, but does not solve the problems of open-loop structural support performance, gaps, and non-adherence

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