58results about How to "Avoid blood loss" patented technology

Methods and apparatus are provided for valve repair or replacement. In one embodiment, the method comprises providing an apparatus having a valve prosthesis, a valve leaflet support and a valve excisor, the apparatus having a first configuration and a second configuration; accessing the aortic root without placing the patient on a heart-lung machine; advancing the apparatus in the first configuration where the valve leaflet support is advanced through a valve, wherein the support is positioned below a valve annulus; expanding the apparatus into a second configuration so that the support will engage the valve; and moving the valve leaflet support and valve excisor together to remove leaflets of the valve. Penetrating members may be advanced into the tissue wherein the penetrating members may act as fasteners to hold the prosthesis in place.

A shunt and method of use for maintaining distal blood flow during an arteriotomy procedure is disclosed. The shunt includes first and second tubular members having proximal ports, distal ports, and lumens therebetween. The distal port of the second tubular member is adapted for releasable attachment to the proximal port of the first tubular member. A second lumen merges and communicates at its distal end with the lumen of the first tubular member and includes a hemostatic valve attached to its proximal end. In using the apparatus for performing open endarterectomy, a filter device is inserted into the vessel and deployed downstream the region of interest in the internal carotid artery. The distal end of the shunt is advanced over the filter device and secured onto the artery. The proximal end of the shunt is inserted upstream the region of interest, typically in the common carotid artery.

A method of performing anastomosis includes securing an access port system to an exterior surface of the target vessel to assist in axial alignment, depth registration, and/or sealing when inserting instruments such as punching instruments and anastomosis instruments into the target vessel.

A catheter with valve for implantation in a vascular structure of a living being. The catheter is in the general shape of a "T" with the top of the "T" implanted within the lumen of a vascular structure, and the leg of the "T" extending out of the vascular structure through an incision in the vascular structure. The lumen of the implanted portion of the catheter completely occupies the lumen of the vascular structure, causing all blood flow through the vascular structure to be directed through the implanted portion of the catheter. A valve is placed in the wall of the implanted portion of the catheter which opens into the lumen of the leg of the "T" of the catheter upon application of sufficient differential pressure between the lumens of the two portions of the catheter. The leg of the "T" is connected to the side wall of the implant portion of the catheter at an angle, such that the axis of the lumen of the leg of the "T" intersects the axis of the lumen of the implanted portion of the catheter at approximately a 45 degree angle.

A pressure activated two-way slit valve assembly is designed to be used in combination with, but not limited to, a high flow rate catheter to prevent accidental ingestion of air or loss of blood if the closure cap comes off during non-use of the catheter. In addition, the potential for occlusion of the catheter due to blood clots in the catheter and catheter related infection is substantially reduced. The pressure activated two-way slit valve assembly includes a first end, a second end, a wall defining a dumbbell shaped channel, and a flexible, thin disk having a slit and positioned within the pressure activated two-way slit valve assembly to reside within the dumbbell shaped channel. The slit and the dumbbell shaped channel are sized to enable the slit to deform in response to a predetermined pressure differential across the slit to allow fluid to pass therethrough.

The present invention relates to an apparatus and method for securing a connector conduit to a hollow organ. The method comprises forming a hole in a wall of the organ; inserting a connector conduit through the hole in the wall of the organ until a flange element comes into contact with the wall of the organ, the flange element being positioned on the connector conduit; and engaging a retention means with the wall of the organ to prevent movement of the connector conduit relative to the wall of the organ, the retention means being positioned on the connector conduit. Exemplary retaining means include a plurality of retaining pins positioned circumferentially around the connector conduit, a plurality of prongs positioned circumferentially around the connector conduit, a balloon positioned on the connector conduit, a torsion spring positioned on the connector conduit, a spiral spring positioned on the connector conduit, or combinations thereof.

Methods and devices to remove thromboembolic material from the human body using rotational energy and aspiration are disclosed. A thromboembolic removal system includes an extraction device and drive unit. The extraction device is introduced to the treatment area and activated by the drive unit to separate, break apart, loosen or soften thromboembolic material and to facilitate its aspiration outside the patient.

Devices and methods are disclosed for achieving hemostasis in patients who have received skin-penetrating wounds to the periphery, including the head, arms, and legs. Such haemostatic packing devices and methods are especially useful in the emergency, trauma surgery, or military setting. The devices utilize fluid impermeable barriers surrounded by exterior dams and pressure to achieve tamponade and hemostasis, primarily by exertion of force to hold the dams against the skin surrounding a wound. The devices are capable of serving as carriers for thrombogenic, antimicrobial or antipathogenic agents. The devices do not require the use of adhesives to work as they are attached to the patient using mechanical locking devices. Peripheral haemostatic packing devices include optional adhesive hemostatic barriers to attach at least a portion of the device to the skin or to assist with initial coupling of a hold-down strap to another strap using a more secure mechanical lock. The peripheral hemostatic packing system does not completely surround the extremity having the wound and therefore do not cause a tourniquet effect. The peripheral hemostatic packing system preferably is held against the skin surrounding a wound by a force that is generally unidirectional and substantially perpendicular to the plane in which the skin of the wound resides.

Methods and devices to remove thromboembolic material from the human body using rotational energy and aspiration are disclosed. A thromboembolic removal system includes an extraction device and drive unit. The extraction device is introduced to the treatment area and activated by the drive unit to separate, break apart, loosen or soften thromboembolic material and to facilitate its aspiration outside the patient.

The invention provides devices, systems and methods for clamping arteries which are useful in reducing or abolishing blood flow in an artery, and may be used to control hemorrhage following a caesarian delivery. A clamping device embodying features of the invention includes a pair of clamping members with opposed pressure-applying members having facing pressure-applying surfaces, at least one of which is a yieldable pressure-applying surface. The yieldable pressure-applying surface is preferably resilient. The clamping members are configured to adjust the distance between pressure-applying surfaces, and a blood flow sensor is disposed on at least one of the pressure-applying members to aid in locating the target artery and also to monitor blood flow through the artery. The clamping device is particularly suitable for occluding uterine arteries by compressing the broad ligament which contains the uterine artery and which is connected to the patient's uterus with the arterial clamp.

Methods and devices for performing endocardiac ablation by accessing the interior of the heart through the wall of the heart at its apex.

This invention is an air block for industrial, medical, and non-medical uses. For example, the air block is connected to the proximal end of a vascular access catheter. The air block is either removably connected to the proximal end of the catheter or it is integral to the proximal end of the catheter. The air block permits introduction of other catheters or instrumentation through its central lumen and on into a lumen of the catheter while minimizing fluid loss or gain into the catheter. The air block further prevents air from entering the catheter and provides for removal of the air or other gas from the central lumen before it can enter the catheter where it could cause harm to the patient. The air block can be attached to various standard proximal catheter terminations including Luer fittings and hemostasis valve outer barrels.

A device and method to constrict or occlude the lumen of a flexible tube may include an occluder under the influence of an elastic force, such as a spring force, that can compress a portion of the wall of the flexible tube. The occluder can be under the influence of the elastic force, but prevented from occluding the tube by a stop. The stop can be connected to a tube gripping feature, so that a pulling force on the tube near the gripping feature can disengage the stop from the occluder, releasing the occluder to compress the tube. In some embodiments, the pulling force applied to the tube causes movement of the gripping feature by taking up slack in a portion of the tube held in the device. In other embodiments, the pulling force applied to the tube causes the tube to stretch elastically near the gripping feature, causing the gripping feature to move, and disengaging the stop from the occluder.

The invention relates to a special clinical nutrition formula for fracture and a preparation method thereof. The special clinical nutrition formula for fracture is prepared from the following raw materials: protein, fat, carbohydrate, dietary fiber, macroelements, trace elements, fat-soluble vitamins, water-soluble vitamins, dietary essences, medicinal and edible components, natural plant compounds and new-resource foods; and the medicinal and edible components are at least one component selected from the following: peppermint, dried citrus reticulata peel, Chinese yams, long-stamen onion bulbs, Chinese wolfberry fruits, Chinese date fruits, longan flesh, and orange peel. The components are prepared into powder in advance, wherein the fat is prepared into fat powder by adopting a micro-capsule embedding technology and the dietary essences are prepared into powder by adopting a freeze-drying technology. The components are accordingly screened and proportioned, so that the special clinical nutrition formula disclosed by the invention is capable of providing complete basic energies and nutrients to the patients with fracture; moreover, components capable of increasing bone density, resisting infection, nourishing the blood and conditioning digestion are added, so that the special clinical nutrition formula is conducive to promoting bone healing, enhancing physical fitness and improving treatment effects on the patients with fracture.

A variable hemostasis valve is disclosed that may be used during medical procedures to prevent blood loss while permitting the percutaneous introduction, operation, and removal of medical instruments. A flexible tubular seal element is disclosed that is disposed within the variable hemostasis valve to provide a fluid-tight, adjustable seal. After insertion of a medical instrument into the valve through at least a portion of the flexible tubular seal element, a proximal portion of the valve housing may be rotated to cause the tension of the flexible tubular seal element to increase over the inserted medical instrument and engage the valve in a closed position. The proximal portion of the valve housing may then be rotated in an opposite direction to release the seal and return the tubular seal element to a relaxed lumen open position.

A method of joining and/or scaling tissues in a surgical procedure or medical treatment, comprising the steps of: (1) applying a matrix protein, a photoactivatable metal-ligand complex and an electron acceptor to a tissue portion; (2) irradiating said tissue portion to photactivate the photoactivatable metal-ligand complex: thereby initiating a cross-linking reaction of the matrix protein to seal said tissue portion or join said tissue portion to an adjacent tissue portion.

The present invention relates to a haemostatic bio-material composition and method for achieving hemostasis. The method for providing hemostasis generally comprises: supplying a dry potassium phosphate based hemostat mixture comprising: monobasic potassium phosphate, a metal oxide, and a tertiary calcium phosphate, wherein the weight percent ratio of monobasic potassium phosphate to metal oxide is between about 3:1 and 1:1; mixing the dry potassium phosphate based hemostat mixture with an aqueous solution forming an activated hemostat slurry; applying an hemostasis-promoting amount of the activated potassium phosphate based hemostat slurry to a site of bleeding; wherein the site of bleeding is in, on, or proximate to bone.

The present invention provides compounds of formula (I):

compositions comprising such compounds; the use of such compounds in therapy (such as asthma or COPD); and methods of treating patients with such compounds; wherein R¹-R¹¹ are as defined herein.

A Chinese medicine 'Tongmailing dripping pill' for treating cardiovasular disease is prepared from 8 Chinese-medicinal materials including red sage root, safflower, rehmannia root, Chuan-xiong rhizome, etc. Its preparing process is also disclosed.

The instant invention provides transgenic plants that express mammalian, e.g., human, recombinant tissue factor (rhTF) as well as methods for making rhTF. The invention further provides rhTF or functional fragment thereof that are obtained from a transgenic plant. The invention also provides methods of treating a subject using the rhTF or a fragment thereof.