1809 results about "Glutaraldehyde product" patented technology

Methods for treating xenogenic tissue for implantation into a human body including in-situ polymerization of a hydrogel polymer in tissue, and tissue treated according to those methods, where the polymerization takes place in tissue that has not been fixed with glutaraldehyde. The polymerization may only fill the tissue, bind the polymer to the tissue, or cross-link the tissue through the polymer, depending on the embodiment. One method includes free radical polymerization of a first vinylic compound, and can include cross-linking through use of a second compound having at least two vinyl groups. Another method utilizes nucleophilic addition polymerization of two compounds, one of which can include PEG and can further include hydrolytically degradable regions. In one embodiment, applicants believe the in-situ polymerization inhibits calcification, and that the polymerization of tissue un-fixed by glutaraldehyde allows for improved penetration of the polymer. The methods find one use in the treatment of porcine heart valve tissue, intended to extend the useful life of the valves by inhibiting calcification. The incorporation of degradable hydrogel regions may initially fill the tissue and reduce any initial inflammatory response, but allow for later infiltration by cells to remodel the tissue.

The invention is a fibrin glue that avoids the use of fibrinogen and thus eliminates the need for premixing and premature clot formation. The fibrin glue of the invention comprises thrombin, thromboplastin and calcium and may have clotting Factors, VII, IX and X, and the like. The invention also comprises a biosealant for use with the fibrin glue without fibrinogen or for use alone. The biosealant is a two component mixture of gelatin/resorcinol and glyoxal/glutaraldehyde/4-(p-maleimidophenyl) butyric acid. The two components are mixed on use.

The invention relates to a method and a reagent for latex sensitization. Specifically, the method for latex sensitization comprises the following steps: combining latex with an unrelated protein by a chemical bond; and then, crosslinking an antigen or an antibody on the unrelated protein by glutaraldehyde so as to cause latex sensitization. The antistreptolysin O latex prepared with the method enhances an immune turbidimetry reagent. With the method disclosed by the invention, time for preparing the reagent can be shortened, and the sensitivity of the reagent is improved.

The invention discloses a preparation method of water-soluble chitosan/polyvinyl alcohol composite films capable of being used as biological package materials. Water-soluble chitosan and polyvinyl alcohol are respectively dissolved in deionized water, the solution is subjected to mixing casting for forming films, then, the films are soaked into one kind of solution or several kinds of mixed solution from glutaraldehyde solution, borax solution, epichlorohydrin, glyoxal and sodium tripolyphosphate to be subjected to crosslinking for 40 to 60 minutes, peeling and natural drying or baking are carried out, and the water-soluble chitosan/polyvinyl alcohol composite films are obtained. The composite films have good antibacterial activity, biocompatibility and biodegradability, in addition, special gas blocking performance and excellent mechanical performance are realized, and the composite films have the advantages of chitosan and the polyvinyl alcohol. In addition, the production cost is low, the preparation process is simple, the production efficiency is high, and the environment is friendly.

An anti-adhesion wound barrier fabricated from amnion obtained from human birth tissue and treated with a glutaraldehyde solution is provided. The amnion is treated in 1% glutaraldehyde solution for up to 15 minutes to fix the amnion. Methods of processing the birth tissue to prepare the amnion for use as a wound barrier are also provided. Use of the amnion anti-adhesion wound barrier for dressing wounds is also described.

An endotoxin adsorbent used for blood perfusion is prepared from agat through adding the aqueous solution to the liquid mixture of toluene and CCl4 to obtain spherical agar, activating by epoxy chloropropane under alkaline condition, reacting on diamine and then on glutaraldehyde to obtain high-strength agar beads used as the carrier of adsorbent, reacting on the amino contained ligand (polymyxin B), and reducing by NaBH4. Its advantages are high compatibility to blood and high effect on absorbing endotoxin from blood.

Long rod shaped M13 viruses were used to fabricate one dimensional (1D) micro- and nanosized diameter fibers by mimic the spinning process of the silk spider. Liquid crystalline virus suspensions were extruded through the micrometer diameter capillary tubes in cross-linking solution (glutaraldehyde). Resulting fibers were tens of micrometers in diameter depending on the inner diameter of the capillary tip. AFM image verified that molecular long axis of the virus fibers were parallel to the fiber long axis. Although aqueous M13 virus suspension could not be spun by electrospinning, M13 viruses suspended in 1,1,1,3,3,3-hexafluoro-2-propanol were spun into fibers. After blending with highly water soluble polymer, polyvinyl 2-pyrolidone (PVP), M13 viruses was spun into continuous uniform virus blended PVP (virus-PVP) fibers. Resulting virus-PVP electrospun fibers showed intact infecting ability to bacterial hosts after suspending in the buffer solution.

A composite adsorbent is prepared from chitosan through dissolving it in the solution of acetic acid, proportionally adding activated carbon powder, adding glutaraldehyde solution, regulating pH value, cross-linking reacting in warm water bath, solid-liquid separation, washing and baking the solid, grinding and sieving. Its advantage is high adsorption and adsorbing speed.

The invention discloses a starch-polyvinyl alcohol dual-degradationplastic film, and relates to the technical field of film production. The starch-polyvinyl alcohol dual-degradation plastic film is made by using the following raw materials, by mass, 50-65 parts of starch, 15-30 parts of polyvinyl alcohol, 5-10 parts of Sa-son seed gum, 2-8 parts of hydroxy propyl cellulose, 5-10 parts of pulullan polysaccharide, 3-6 parts of nanometer silica, 5-10 parts of zinc stearate, 4-8 parts of oxidized polyethlene wax, 2-4 parts of ethyl silicon oil, 3-5 parts of calcium carbonate, 4-10 parts of glutaraldehyde and 3-5 parts of octodecyl alcohol. The plastic film made in the invention has biological and optical degradation effects, can effectively solve the white pollution problem caused by difficult degradation of common plastic films, and has the advantages of simple production technology, low cost and industrial production benefiting.

The invention belongs to the field of biomedical engineering materials, and discloses a loaded chitosan (CS)/sodium alginate (SALG) double-crosslinking hydrogel with a colon target and a preparation method and an application thereof. In the invention, the hydrogel is firstly crosslinked with chitosan and then with sodium alginate, the medicine is wrapped in the chitosan, the sodium alginate is coated on the outer layer, and then double crosslinking is performed by the calcium ion and glutaraldehyde, the carboxy and amine are both fixed to form an interpenetrated network, and such a structure is not easy to be degraded and not easy to lose in the body fluid of human beings. After medicine loading, a small amount of medicine can be released after two hours in the gastric juice, and nearly no medicine is released after 4 hours in the intestine, while more medicine is released in the colon, and long-time release can be realized, which makes up the medicine burst release, medicine leakage and easy degradation and loose of materials reflected by the loaded gel prepared in the above, and colon targeting positioning and long-time release of medicine for treatment can be realized.

The present invention discloses one kind of polyurethane base biological immobile carrier. The carrier has three kinds of structures: macroporous polyurethane network; polyurethane cross-linked chitosan and coated active carbon; and microporous network formed with chitosan and cross-linked glutaraldehyde, chloropropylene oxide or chloroacetic acid. These three kinds of network interpenetrate to form the polymer capable of fixing bioactive molecule. The carrier of the present invention has the features of coexisting macropores and micropores, coexisting hydrophilicity and reaction property, coexisting powerful adsorption and strong polarity, high biological bearing capacity, good compatibility, high physical, chemical and mechanical performance, etc., and is suitable for various bioreactors for treating sewage.

A composite disinfectant containing dialkyl quaternary ammonium salt for disinfecting the circulated cooling water contains at least one dialkyl quaternary ammonium salt disinfectant and at least one non-oxide disinfectant chosen from frequency used quaternary ammonium salt, isothiazolinone, glutaraldehyde, and bithiocyanomethane.

Provided is a biocidal composition comprising glutaraldehyde and an oxazolidine biocidal compound. The composition is useful for controlling microorganisms in aqueous or water containing systems such as found in oil and natural gas production.

Disclosed is a process for preparing nitrogen self-doped hierarchical porous oxide in the technical field of functional material by employing biological templates, steps of which comprises 1) selecting fresh biomaterial to fix in glutaraldehyde PBS stationary liquid, 2) soaking the biomaterial, after being rinsed by pure water and fixed, in HCl, then rinsing the biomaterial by distilled water for a plurality of times, soaking the biomaterial in salt solution of metal M, 3) rinsing the biomaterial obtained from step 2) by pure water, soaking in the salt solution of metal M, 4) rinsing the obtained biomaterial from step 3) to obtain biomaterial which is naturally dried, then heating within the range of 500-1000 DEG C in an oxygen atmosphere and insulating to obtain the nitrogen-doped porous oxide N-MxOy. The nitrogen self-doped porous oxide prepared by the invention not only is provided with a biological porous structure, but also effectively realizes nitrogen self-doping, and has the obviously strengthened advantage of capturing and absorbing light wave with different wave ranges.

The present invention discloses a liquid high-effective disinfectant. It is formed from (wt%) 1-2% of hyamine which is the mixture of alkyl dimethyl benzyl ammonium chloride and dialkyl dimethyl ammonium chloride, 0.1-0.5% of biguanide which is one of chlorhexidine and polyhexamethylene biguanide salt or their mixture, 3-8% of aldehyde which is one of glutaraldehyde, citrial, jasminal and myristic aldehyde or mixture of more than two kinds of them, 5-10% of surfactant, 1-5% of urea, 40-50% of hydrophilic solvent, 0.1% of EDTA sodium salt, 2.5-35% of water and 0-3% of selectable components, such as aromatic compound, colouring matter and viscosity-regulating agent.

The invention discloses a method for preparing sulfured magnetic chitosan and a method for treating waste water containing heavy metals by using the sulfured magnetic chitosan, which belong to the technical field of material preparation. The method for preparing the sulfured magnetic chitosan comprises: dispersing a ferrous salt and a ferric salt in acetic acid solution of chitosan in advance; dripping the mixed solution into alkaline solution by using an injector to form magnetic chitosan spheres; crosslinking the spheres by using glutaraldehyde to form crosslinked magnetic chitosan spheres;and drying under vacuum, grinding into powder and obtaining the sulfured magnetic chitosan. The prepared material is used for treating waste water containing heavy metals.

Disclosed are hydrogels wherein a polymer matrix is modified to contain a bifunctional poly(alkylene glycol) molecule covalently bonded to the polymer matrix. The hydrogels can be cross-linked using, for example, glutaraldehyde. The hydrogels may also be crosslinked via an interpenetrating network of a photopolymerizable acrylates. The hydrogels may also be modified to have pharmacologically-active agents covalently bonded to the poly(alkylene glycol) molecules or entrained within the hydrogel. Living cells may also be entrained within the hydrogels.

Disclosed is a method for production of a bio-derived scaffold for use in regenerative medicine, which has a bio-compatibility and biodegradability and can self-organize and grow without causing calcification. The method comprises the steps of partially fixing a biological soft tissue with glutaraldehyde by cross-linking and incubating the partially fixed tissue together with an elastase.

The process provides one kind of polishing wax and its preparation process. The polishing wax consists of silicone oil 3-8 wt%, vaseline 0.2-5 wt%, polyethylene 0.1-8 wt%, montan wax 0.1-0.5 wt%, coumarone-indene resin 0.1-5 wt%, carnauba wax 0.1-1 wt%, C12 fatty alcohol polyoxyethylene ether 0.5-3 wt%, nonylphenol polyoxyethylene ether 1-5 wt%, alkyl alcohol amide 2-5 wt%, ammonium hexadecyl trimethyl chloride or ammonium octadecyl trimethyl chloride 2-8 wt%, bentonite 1-5 wt%, glutaraldehyde 0.05-0.1 wt% and water 46.4-89.85 wt%. The polishing wax has no corrosion to the paint surface, and can eliminate dirt from paint surface, make paint surface clean and bright, and form protecting film with high heat resistance, less ageing and good luster.