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Pharmaceutical composition, and preparation method, preparation and application thereof

A composition and drug technology, applied in the field of pharmaceutical composition and its preparation, can solve the problems of expensive drugs and unsatisfactory symptom improvement effects

Active Publication Date: 2016-08-10
昆明市中医医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine has many types of drugs to control high blood pressure, but the effect of improving symptoms is not satisfactory. Although some blood pressure has been controlled to normal, the above symptoms still persist, and most of the drugs are expensive

Method used

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  • Pharmaceutical composition, and preparation method, preparation and application thereof
  • Pharmaceutical composition, and preparation method, preparation and application thereof

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preparation example Construction

[0016] The preparation method of the pharmaceutical composition includes the steps of extraction, concentration and drying, specifically:

[0017] A: Uncaria uncariae is extracted with ethanol, concentrated, dried to a dry paste, and the residue is filtered for later use;

[0018] B: Crush rice into fine powder, set aside;

[0019] C: The remaining rice and Uncaria medicinal residues are mixed with the remaining raw materials, extracted with water, filtered, concentrated to a thick paste, dried to a dry paste, added with Uncaria dry paste, mixed evenly, and crushed into fine powder to obtain the described pharmaceutical composition.

[0020] The preparation of the pharmaceutical composition is to add pharmaceutically acceptable auxiliary materials to the pharmaceutical composition to prepare tablets, powders, oral liquids, capsules, granules, drop pills or honeyed pills.

[0021] The application of the pharmaceutical composition in the preparation of hypertensive disease and...

Embodiment 1

[0024] Prepare 15-24 parts of Sangjisheng, 15-24 parts of Astragalus, 10-15 parts of Radix Polygoni Multiflori, 8-15 parts of Raw Paeoniae Alba, 12-18 parts of Fried Eucommia, 8-12 parts of Angelica, 3-8 parts of Chuanxiong, Salvia miltiorrhiza 8~12 parts, 8~12 parts of Gastrodia elata, 15~20 parts of Uncaria, 15~20 parts of Noctilucia. Uncaria is extracted with ethanol and dried to a dry paste, and the residue is filtered for later use; the rice millet is crushed into fine powder for later use; the remaining rice millet and Uncaria medicinal residue are mixed with the remaining nine herbs, and 5 to 10 times the amount of water is added to extract 2 to 4 times. Each time for 1~2 hours, filter and concentrate to a thick paste. After being dried to a dry paste by vacuum box drying method, the dry paste of Uncaria vulgaris is added, mixed evenly, and pulverized into fine powder to obtain the target pharmaceutical composition.

Embodiment 2

[0026] Prepare 15-24 parts of Sangjisheng, 15-24 parts of Astragalus, 10-15 parts of Radix Polygoni Multiflori, 8-15 parts of Raw Paeoniae Alba, 12-18 parts of Fried Eucommia, 8-12 parts of Angelica, 3-8 parts of Chuanxiong, Salvia miltiorrhiza 8~12 servings, 8~12 servings of Gastrodia elata, 15~20 servings of Uncaria, 15~20 servings of Nightingalia vine, 15~20 servings of sorghum rice, 12~18 servings of fried grain buds, 12~18 servings of fried malt, 3 servings of Phellodendron cork ~8 servings. Uncaria is extracted with ethanol and dried to a dry paste, and the residue is filtered for later use; the rice millet is crushed into fine powder for later use; the remaining rice millet and Uncaria medicinal residue are mixed with the remaining thirteen herbs, and 5 to 10 times the amount of water is added to extract 2 to 4 times , 1-2 hours each time, filtered, and concentrated to a thick paste. After being dried to a dry paste by vacuum box drying method, the dry paste of Uncaria...

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PUM

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Abstract

The invention discloses a pharmaceutical composition, and a preparation method, a preparation and application thereof. The pharmaceutical composition comprises the following bulk drugs by weight: 15 to 24 parts of taxillus, 15 to 24 parts of Radix Astragali, 10 to 15 parts of prepared fleece flower root, 8 to 15 parts of raw white peony root, 12 to 18 parts of stir-fried eucommia bark, 8 to 12 parts of Chinese angelica, 3 to 8 parts of Ligusticum wallichii, 8 to 12 parts of red sage root, 8 to 12 parts of gastrodia tuber, 15 to 20 parts of uncaria and 15 to 20 parts of fleeceflower stem. The pharmaceutical composition is prepared through extraction, concentration and drying. The preparation method comprises the following steps: pretreatment, extraction, concentration and drying. The preparation is a tablet, powder, oral liquid, capsule, granule, pill or honeyed pill prepared from the pharmaceutical composition and pharmaceutically acceptable adjuvant. The pharmaceutical composition is applied to preparation of drugs used for treating hypertension and target-organ damages caused by hypertension, e.g., cerebrovascular diseases, hypertensive heart diseases and hypertensive renal damage. Through combination and cooperation of the bulk drugs of the pharmaceutical composition, the pharmaceutical composition is capable of nourishing yin at first and reducing yang next, enables the kidney and brain to be nourished and the liver to be calmed, nourishes the liver and the kidney, extinguishes wind and dredges collaterals; so high blood pressure is lowered.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparation, and in particular relates to a pharmaceutical composition, a preparation method, preparation and application thereof. Background technique [0002] Hypertension, target organ damage caused by hypertension, such as cerebrovascular disease, hypertensive heart disease, hypertensive kidney damage, the main clinical manifestations are dizziness, dizziness, poor sleep, upset, dry mouth, bitter mouth, Red eyes and red eyes, dry stool, turbid or foamy urine, dark tongue, thin yellow fur, thready and stringy pulse. This series of symptoms is most common in clinical medicine, and some patients cannot be determined by a Western medicine disease name, and some are even classified as psychological diseases. In severe cases, organic diseases may develop progressively. Western medicine has many types of drugs for controlling hypertension, but the effect of improving symptoms is...

Claims

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Application Information

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IPC IPC(8): A61K36/8988A61K36/8998A61K9/14A61P9/12A61P9/00A61P13/12
CPCA61K9/14A61K36/185A61K36/232A61K36/258A61K36/28A61K36/46A61K36/481A61K36/537A61K36/60A61K36/65A61K36/704A61K36/71A61K36/74A61K36/756A61K36/8988A61K36/899A61K36/8998A61K2236/331A61K2236/51A61K2236/53A61K2300/00
Inventor 陆家龙魏丹霞陆玉姬顾力华余晓玲陈斌施兴黔杨海玲陈云山
Owner 昆明市中医医院
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