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Shuguan extractive for treating coronary heart disease, and its oral preparation

An oral preparation and extract technology, applied in the field of pure traditional Chinese medicine extracts, can solve the problems of environmental pollution, long dissolution time, poor absorption, etc.

Inactive Publication Date: 2006-06-28
SHAANXI HONGFU YIYUE PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Coronary heart disease has both acute and chronic characteristics. Usually, it is necessary to take continuous daily treatment drugs. In actual use, most of them need to take two or more drugs at the same time, and special emergency drugs need to be prepared at any time. The existing treatment and prevention Most of the drugs have a single effect, and there are few practical drugs used for emergency and stable treatment, which brings inconvenience to clinical treatment and family medicine
[0004] At the same time, due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicines, have long dissolution time, low dissolution rate, poor absorption, hepatic first-pass effect and low bioavailability after taking. And other problems, which affect the efficacy of the drug, but also directly affect the therapeutic effect
In addition, conventional oral dosage forms, such as tablets, capsules, granules (infusions), etc., due to the granulation process in the preparation process, will generate relatively large dust pollution, which will cause health problems to the staff to a certain extent. harm, and also cause some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
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Effect test

Embodiment Construction

[0036] Now with several groups of specific examples, the preparation method of Shuguan pure Chinese medicine extract and Shuguan dropping pills involved in the present invention will be further described. For other conventional oral preparations, due to mature technology and easy preparation, the examples are not listed separately.

[0037] [Preparation of dry powder of Shuguan extract]

[0038] Take 100g of borneol, 300g of goose, 150g of clove, 200g of notoginseng, 200g of red ginseng, 150g of cinnamon, 150g of mustard seed, and the above three flavors, take red ginseng, notoginseng, and mustard seed and grind them into the coarsest powder, add 80% ethanol and heat and reflux for extraction twice , add 5 times the amount for the first time to extract for 1.5 hours, add 4 times the amount for the second time to extract for 1.0 hours, combine the filtrates, recover the ethanol under reduced pressure to obtain a concentrated solution, and set aside; take goose, cloves, and cinn...

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PUM

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Abstract

A Chinese medicine in the form of dripping pill, micropill, concentrated pill, tablet, capsule, particle, or oral liquid for treating coronary heart disease and angina pectoris is prepared from 7 Chinese-medicinal materials including borneol, cloves, notoginseng, cinnamon bark, etc.

Description

technical field [0001] The present invention relates to a pure Chinese medicine extract used for preparing preparations for treating acute and chronic coronary heart disease, in particular to a pure Chinese medicine extract prepared from ginseng, clove, borneol, goose herb, cinnamon, mustard seed and notoginseng. And different oral preparations prepared from this extract. Background technique [0002] Cardiovascular disease is a common and frequently-occurring disease that seriously endangers human life and health. In the late 20th century, the incidence of cardiovascular diseases in western developed countries increased sharply, and the mortality rate remained high, becoming the number one killer that threatened health. mortality rate as a national policy. According to relevant statistics in recent years, people who die from cardiovascular and cerebrovascular diseases account for about half of the cause of death in my country every year. Hypertension, stroke and coronary...

Claims

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Application Information

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IPC IPC(8): A61K36/63A61P9/10
Inventor 贾旭芝程丑夫
Owner SHAANXI HONGFU YIYUE PHARMA
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