Herba violae extract with antihypertensive effect

A technology of viola ditin and its extract, which is applied in the field of medicine to achieve the effects of dilating coronary arteries, stably lowering blood pressure, and having no toxic side effects

Inactive Publication Date: 2016-09-07
陈瑞
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no report on the treatment of hypertension with its extract

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Grind Viola dichotoma to 80 mesh, add distilled water 10 times the weight of Viola dichotoma, and treat it under a microwave with a power of 120W for 30 minutes, stand still to take the upper layer of clear liquid, keep the residue, and put the upper layer of clear liquid at a vacuum degree of 0.098mpa, Concentrate to a thick paste with a water content of 8% under a rotary evaporator with a rotation speed of 100rpm and a temperature of 80-82°C, vacuum-dry the thick paste, and pulverize it into powder A;

[0014] Add 85% ethanol of 8 times the volume of the residue to the residue, reflux extraction at 77°C for 1 hour, and concentrate the extract to The thick paste with a water content of 8% is vacuum-dried and crushed into powder B;

[0015] The powder A is mixed with the powder B to obtain Viola extract with antihypertensive effect.

[0016] The Viola dicin extract with antihypertensive effect contains 0.15 mg / g of afodouside, 0.06 mg / g of succinic acid, 0.33 mg / g of a...

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PUM

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Abstract

The invention relates to the technical field of medicine, in particular to a herba violae extract with an antihypertensive effect. The extract is prepared through the method comprising the following steps: smashing herba violae, adding distilled water for microwave extraction, standing to get supernatant liquid, maintaining residues, concentrating the supernatant liquid under a rotary evaporator to form a paste with the water content of 8%, carrying out vacuum drying on the paste, smashing the paste into powder A, adding ethyl alcohol into the residues for carrying out reflux extraction for 1 hour, concentrating an extracting solution under the rotary evaporator to form paste with the water content of 8%, carrying out vacuum drying on the paste, smashing the paste into powder B, and mixing the powder A with the powder B to form the herba violae extract with the antihypertensive effect. The herba violae extract with the antihypertensive effect disclosed by the invention has the effects of strengthening blood capillary resistance, expanding coronary artery and increasing the blood flow volume of the coronary artery, and the blood pressure is reduced stably without toxic or side effect.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a Viola didin extract with antihypertensive effect. Background technique [0002] Zihuadiding, also known as Viola Diding, is the rooted whole plant of Zihuadiding or Viola, which has the functions of clearing heat and detoxifying, cooling blood and reducing swelling, clearing heat and promoting dampness, and is mainly used to treat boils, carbuncles, scrofula, and jaundice. , Dysentery, diarrhea, conjunctival congestion, sore throat, poisonous snake bites, from the perspective of clinical application, Viola didin extract is mostly used for respiratory tract infection, hands, feet, moss head. At present, there is no report on the treatment of hypertension with its extract. Contents of the invention [0003] The object of the present invention is to provide a Viola dipin extract with antihypertensive effect. [0004] A viola extract with antihypertensive effect, prepared by t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/86A61P9/12
CPCA61K36/86A61K2236/331A61K2236/333A61K2236/39A61K2236/51
Inventor 陈瑞
Owner 陈瑞
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