92results about How to "With antihypertensive effect" patented technology

The invention discloses a method for preparing angiotensin converting enzyme inhibitory peptide (ACEIP) by using enzymatic degradation on mussel-digested protein, which comprises the following steps: 1) mixing defatted dry mussel powder or mussel protein powder serving as raw material with water, then adjusting the pH value to 9.0 to 9.5 so as to obtain a mixed liquor; 2) raising the temperature of the mixed liquor to 60 to 65 DEG C for preheating, then adding alkali protease into the mixed liquor to carry out zymolysing reaction, wherein the zymolysing temperature is 60 to 65 DEG C and the zymolysing time is 180 to 240 minutes; and 3) carrying out enzyme inactivation processing on zymolysing products obtained in step 2 firstly so as to obtain zymolysing liquid; then sequentially carrying out ultra-filtration, freeze drying and chromatography on the obtained zymolysing liquid so as to obtain the ACEIP. The ACEIP prepared by using the method of the invention has the characteristic of strong activity.

The invention provides a traditional Chinese medicine for treating hypertension. The traditional Chinese medicine is prepared from the following components in parts by weight: 20 parts of uncaria rhynchophylla, 20 parts of concha haliotidis, 15 parts of eucommia bark, 15 parts of kudzuvine root, 20 parts of cassia seed, 15 parts of tree peony bark, 10 parts of radix scutellariae, 10 parts of Chinese wolfberry root-bark, 15 parts of white peony root, 15 parts of bupleurum root, 10 parts of gastrodia tuber, 15 parts of achyranthes root, 15 parts of Chinese taxillus twig, 15 parts of lumbricus, 15 parts of motherwort and 15 parts of fleece-flower stem. The components are mixed and pulverized and then the pulverized mixture is packaged with small paper medicine bags. After being drunk, the traditional Chinese medicine is absorbed in body so as to reach treatment effect; and the traditional Chinese medicine has the advantages of no side effects and obvious treatment effect on hypertension,and is convenient in use.

The invention relates to a health preserving coarse cereal having a health-care function. The health preserving coarse cereal is prepared from wheat, barley, peas, mung bean, oat, buckwheat, black glutinous rice, red bean, Chinese yam, corn, seeds of Job's tears, black soya bean, chrysanthemum, carrot, root of spinach, white gourd and pumpkin by weight, has the effects of softening blood vessels, stabilizing blood sugar, lowering down serum cholesterol, preventing outbreak of cancers, hypertension and coronary heart disease, increasing the concentration of histamine, enabling peripheral blood vessels to expand, reducing blood pressure, enabling internal secretion to maintain normal and delaying aging, and is extremely easy to popularize.

The invention discloses a preparation method for peanut bioactive peptide. The method comprises the following steps: adding peanut protein powder to distilled water, carrying out stirring, followed by standing and microwave treatment to obtain peanut protein powder suspension liquid; adjusting a pH value of the peanut protein powder suspension liquid through a hydrochloric acid solution, then adding compound plant hydrolase Viscozyme L, followed by carrying out the microwave treatment to secondarily carry out enzymolysis to obtain a enzymatic hydrolysate, then killing the enzymes and carryingout cooling to a room temperature; adjusting a pH value of the enzymatic hydrolysate through a sodium hydroxide solution or the hydrochloric acid solution, then adding protease and carrying out the microwave treatment to secondarily carry out the enzymolysis, then killing the protease and carrying out cooling to the room temperature, followed by carrying out centrifugating and freeze drying to obtain the peanut bioactive peptide. The prepared peanut bioactive peptide product provided by the present invention has functional properties of high dissolubility, high emulsibility, strong foamability, good emulsion stability, good foam stability and the like. In addition, the method provided by the present invention is applicable for the industrial production.

The invention discloses a rapid preparation method of a mussel protein antihypertensive peptide. The antihypertensive peptide is characterized in that an amino acid sequence of the antihypertensive peptide is Val-Ser-Trp-Pro-Cys-Arg-Trp(VSWPCRW); the molecular weight determined by ESI-MS (electrospray ionization mass spectrometry) is 935.07Da. The active peptide Val-Ser-Trp-Pro-Cys-Arg-Trp is obtained by shelling mussels, taking the meat of the mussels, carrying out enzymolysis on the meat, carrying out ultrafiltration on the enzymatic hydrolysate, adsorbing the enzymatic hydrolysate with an agarose magnetic microsphere immobilized ACE (angiotensin converting enzyme) and carrying out purification by RP-HPLC (reversed-phase high-performance liquid chromatography). The active peptide prepared by the invention has obvious ACE inhibitory activity and can be used in hypertension treatment related drugs.

The invention discloses antihypertensive shrimp chili sauce. The antihypertensive shrimp chili sauce comprises the following active ingredients in parts by weight: 60-65 parts of shrimp, 20-30 parts of pepper, 7-8 parts of Chinese cabbages, 4-6 parts of tomatoes, 1-2 parts of radix puerariae, 3-4 parts of water fennels, 1-2 parts of radix angelicae, 2-3 parts of rhizome polygonatum, 1-2 parts of semen cassiae, 2-3 parts of ganoderma lucidum, 1-2 parts of herba epimedii, 2-3 parts of gynostemma pentaphyllum, 1-2 parts of chestnut leaves, 1-2 parts of lophatherum gracile, 1-2 parts of lotus flowers, 1-3 parts of flos puerariae, 1-2 parts of Chinese hawthorn leaves, 2-3 parts of peanut oil, 2-3 parts of dried scallion, 1-2 parts of Chinese chive seeds, and proper edible salt, water and aniseeds. The produced antihypertensive shrimp chili sauce is spicy and tasty, has high health-care values, the water fennel has the effect of calming the liver and reducing the blood pressure, the radix puerariae, rhizome polygonatum, radix angelicae, herba epimedii, ganoderma lucidum semen cassiae and the like have certain antihypertension effect, and the shrimp chili sauce is especially applicable for hypertension groups to eat, and is capable of reducing the blood pressure, strengthening the physique and maintaining the human health after being eaten for a long time.

The present invention relates to chrysanthemum health pillow, and belongs to field of traditional Chinese medicine. Composition in health pillow core is constituted by material medicament by weight percent: chrysanthemum 40%-70%, Ligusticum chuanxiong 15%-30%, peony bark5%-15% and Angelicae dahuricae 5%-15%. The four kinds of medicinal herbs cooperate with each other and strengthens the medicinal power. People will feel clear and freshly by using chrysanthemum pillow regularly which can achieve the aim of reducing blood pressure.

The invention disclosed a kind of spirulina which contains spirulina active peptide, protease and kinas, the preparing method and application is also included in the invention. The spirulina contains all round nutrients and has the function of regulating the body blood fat, but the function is very mild and slow. Besides, there are no reports about the molecular spirulina active peptide, protease and kinas existing in spirulina. The invention has fermented the spirulina with Bacillus subtitles to get spirulina that contains spirulina active peptide, protease and kinas. The detecting results show that the spirulina contains 15-40% (W/W) active peptide, 100-10000U/g protease and 1000-80000FU/g kinas when the water content of the spirulina is lower than 7%. The clinical examination shows that the invention has the function of dissolving thrombus, preventing high viscosity blood disease, and hypertensive disease.

The invention relates to an anti-flash evaporation valve, belonging to the valve field, which is characterized in that the anti-flash evaporation structure of the valve is composed of at least two layers of sleeves arranged between a valve clack and a valve body. The circumferential walls of the inner and outer sleeves are respectively opened with a throttle window, and the arrangement between the inner and outer sleeves is mutually staggered at a certain angle. The invention has the advantages of that the processing assembly technology of the sleeve is much simpler than the existing labyrinth anti-flash evaporation structure, and the pressure reducing effect and the anti-flash evaporation capacity are much stronger than the foreign multi-layer sleeve anti-flash evaporation structure and are basically equal to the labyrinth anti-flash evaporation structure. Therefore, the invention can be widely used in the places which have the high differential pressure and easily generate the flash evaporation and cavitation erosion in order to protect valves, pipelines and other equipments.

The invention belongs to the field of functional food production through microbial fermentation, and relates to probiotic fermented functional food capable of dispelling hangover and nourishing liverand a preparation method thereof. The probiotic fermented functional food is prepared by the following steps: pulverizing soybeans, turmeric and hovenia dulcis thunb, proportionally mixing the materials, and carrying out segmented solid-state fermentation by using bacillus coagulans, pediococcus acidilactici, bifidobacterium animalis, lactobacillus plantarum, lactobacillus paracasei and bacillus subtilis. According to the functional food, the content of probiotics in the product is effectively increased, the content and variety of beneficial substances in the product can be increased, some macromolecular substances can be converted into micromolecular substances, absorption by a human body is facilitated, the efficacy of the functional food in the aspects of dispelling hangover and nourishing liver is enhanced, and the functional food has the efficacy of regulating intestinal health. Besides, a large amount of lactic acid can be generated through fermentation of probiotics in the product, growth of spoilage microorganisms can be effectively inhibited, the shelf life of the product can be prolonged, preservatives do not need to be added, and the quality of the product is not affected.

The invention discloses a spirulina with active spirulina peptide and spirulina prolease and preparing method and application, which is characterized by the following: adjusting human blood fat; adopting bacillus subtilis to ferment spirulina; making the active spirulina peptide at 15-40% when the water content is under 7%; possessing 1000-40000U/g spirulina prolease.

The invention discloses a sheep hemoglobin blood pressure reduction peptide and a method for preparing the same. The method comprises the following steps: sheep hemoglobin dry powder is dissolved in distilled water and kept warm at a temperature of between 70 and 80 DEG C for 5 to 10 minutes, and the sheep hemoglobin solution is added with alkali protease to perform the hydrolysis reaction at a temperature of between 50 and 60 DEG C and a pH value of between 7.5 and 8.5 for 4 to 6 hours, and the obtained sheep hemoglobin enzymolysis solution is subjected to ultrafiltration, desalting, and centrifugal spray drying, finally the sheep hemoglobin blood pressure reduction peptide is obtained. The blood pressure reduction peptide has the advantages that: firstly, the blood pressure reduction peptide has strong capability of reducing blood pressure, of which the IC50 value is between 0.78 and 0.86mg/mL, and the ACE inhibition activity reaches 92 to 95 percent; secondly, the blood pressure reduction peptide only takes effect of pressure reduction on a hypertension patient, so that the over-reduction problem of blood pressure is not existed; thirdly, the blood pressure reduction peptide is extremely high in safety and has no toxic and side effects; and fourthly, the preparation method is low in cost. The sheep hemoglobin blood pressure reduction peptide can also be used as a nutrient health product.

The invention relates to a pharmaceutical composition for treating diabetic nephropathy. Based on traditional Chinese medicine theories, the pharmaceutical composition comprises traditional Chinese medicine raw material medicines such as cooked rehmannia root, astragalus root, polygonati, salvia root, Chinese yam, white atratylodes rhizome, atractylodes rhizome, notoginseng root, alisma rhizome, and poria, has the effects of tonifying qi and yin, and clearing dampness and dredging collaterals; and is used for treating the diabetic nephropathy.

A Chinese medicine in the form of honeyed pills for treating nasosinusitis, especially the chronic one, is prepared from 10 Chinese-medicinal materials including honeysuckle flower, chrysanthemum flower, bouttuynia, tendrilled fritillary bulb, etc through proportioning, respective grinding, mixing, sieving, honeying and pilling.

The invention discloses Dong-minority nourishing healthcare tea oil. The Dong-minority nourishing healthcare tea oil comprises the following ingredients in parts by weight: 30-40 parts of tea oil, 8-10 parts of Yinmi, 28-36 parts of oil nuts, 5-8 parts of fried peanut kernels, 1-2 parts of fried soybeans, 5-8 parts of cactus juice, 12-15 parts of Isomalt, 3-5 parts of wine, 6-8 parts of astragalus roots, 3-8 parts of rhiizoma dioscoreae from Hena of China, 8-12 parts of Chinese angelica roots, 8-12 parts of lotus-root starch, 9-15 parts of pumpkin powder, 9-12 parts of Arenga pinnata powder, 9-11 parts of tea leaves, 48-52 parts of lard, 35-45 parts of table salt, 15-25 parts of pig livers, 15-25 parts of pig small-intestines and 10-15 parts of green onions. The invention further discloses a preparation method of Dong-minority nourishing healthcare tea oil. According to the preparation method, the raw materials are scientifically formulated; moreover, the medicinal materials, the cactus juice, the Isomalt and the wine are added into the formula, so that the Dong-minority nourishing healthcare tea oil is fresh and delicious in taste. In addition, the wine has the function of treating cardio-cerebral syndromes and the combination of the wine with the cactus juice has certain effects in reducing blood sugar, sliming and lowering blood pressure. The Dong-minority nourishing healthcare tea oil not only has good taste, but also has healthcare and disease-treating functions.

The invention relates to a lemonish tea health-care pillow. The pillow comprises a pillowcase, a pillow inner and a pillow adjusting pad, wherein tea leaves and/or tea stalks and lemon leaves and/or lemon branches are main raw materials of the pillow inner, while silkworm excrement, cassia seeds and Chinese mugwort leaves are used as auxiliary materials of the pillow inner. The lemonish tea health-care pillow is integrated with comfort, fashion and health-care physical therapy, has good air permeability, can emit fresh and pleasant lemonish fragrance, has the health-care functions of tranquilizing and allaying excitement, and also has excellent hypnotizing effect.

The invention discloses a food-borne beef tendon ACE (Angiotensin Converting Enzyme) inhibition peptide, fruit and vegetable chewable tablets and a preparation method thereof. The food-borne beef tendon ACE inhibition peptide is prepared through the following steps of: immersing cleaned beef tendon blocks through an acetic acid solution, carrying out primary enzymolysis through pepsin and filtering; centrifuging filtrate to obtain supernatant, adding salt and centrifuging; removing salt from sediment, and freezing and drying to obtain collagen; carrying out secondary enzymolysis on the collagen through alkali protease; centrifuging the supernatant and filtering through an acetate fiber filter with the pore diameter of 0.45 mum; freezing and drying a filtered product in vacuum to obtain thefood-borne beef tendon ACE inhibition peptide. Eggplants, roxburgh rose powder, sea buckthorn powder and the food-borne beef tendon ACE inhibition peptide are used as raw materials and are granulatedthrough a wet process; finally, a mixture is pressed to prepare the chewable tablets; a formula is optimized by applying a response surface test and an optimal formula of the fruit and vegetable chewable tablets is determined; finally, the fruit and vegetable chewable tablets which are fragrant, sweet and palatable, have abundant nutrients and have health-care functions of lowering blood pressure, preventing cardiovascular diseases and the like are obtained.

The invention discloses an effective part composition containing corn stigma extract and a preparation method and application of the effective part composition. The effective part composition is formed by using the corn stigma extract and white tea extract as main ingredients and adding ginseng powder, Chinese yam powder, Semen coicis powder and buckwheat powder. Raw materials are all natural plant resources which are both medicinal and edible and plant effective part extract, the effective part composition can be prepared into healthcare products various in dosage form, and the effective part composition has hypotensive efficacy, and is free of toxic and side effect if being drunk for a long time.

The invention provides a method for preparing ACE (Angiotensin Converting Enzyme) inhibitory peptides through substep enzymatic hydrolysis of feta protein. The method comprises the following steps of: cooling and centrifuging recovered feta for degreasing to obtain skimmed milk, using the skimmed mild for preparing casein by isoelectric precipitation, firstly hydrolyzing the casein with Alcalase to obtain hydrolysate containing the ACE inhibitory peptides through optimization of hydrolysis condition, and performing optimization of neutral protease and trypsin hydrolysis conditions by taking the hydrolysate as a substrate to obtain small-molecule peptides with high ACE inhibitory activity through. The inhibitory proportion of an ACE inhibitory peptide product prepared by the method can reach above 90%; and the ACE inhibitory peptide product has the characteristics of being diversified in variety of the ACE inhibitory peptides, having small fragments, being beneficial to the separation and purification of the small-molecule peptides and being high in inhibitory proportion.

The invention discloses an application of a mussel protein antihypertensive peptide. The antihypertensive peptide has antihypertensive activity and is characterized in that an amino acid sequence of the antihypertensive peptide is Val-Ser-Trp-Pro-Cys-Arg-Trp(VSWPCRW); the molecular weight determined by ESI-MS (electrospray ionization mass spectrometry) is 935.07Da. The active peptide Val-Ser-Trp-Pro-Cys-Arg-Trp is obtained by shelling mussels, taking the meat of the mussels, carrying out enzymolysis on the meat, carrying out ultrafiltration on the enzymatic hydrolysate, adsorbing the enzymatic hydrolysate with an agarose magnetic microsphere immobilized ACE (angiotensin converting enzyme) and carrying out purification by RP-HPLC (reversed-phase high-performance liquid chromatography). The active peptide prepared by the invention has obvious ACE inhibitory activity and can be used in hypertension treatment related drugs.

An intelligent electric energy meter adopting 2.4 G radio communication in place of infrared communication is disclosed and relates to the technical field of intelligent electric energy meters. The intelligent electric energy meter includes a microprocessor, and includes an electric energy metering chip, a liquid crystal driving and display module, a power supply module, a backup battery module, a daily-timing circuit module, a memorizer module, an electric energy pulse output module, a button inputting module, an RS485 communication module, a radio communication module and an ESAM security certificating module which are connected to the microprocessor. The electric energy metering chip is connected to a voltage collecting module, a current collecting module and a zero-line current sampling module, and is connected to the electric energy pulse output module. The radio communication module is a 2.4G radio module. The intelligent electric energy meter adopts the 2.4G radio module through which a manager can read data of the electric energy meter in a remote, rapid and large-scale manner, thus facilitating management of electric energy utilization information.

The invention discloses a traditional Chinese medicine for treating diabetes mellitus. The traditional Chinese medicine comprises capillary wormwood herb, white mulberry root-bark, corn stigma, gizzard pepsin, semen sesami nigrum, dried sophora flower, trogopterus dung, liquorice, purslane and the like. The traditional Chinese medicine has the advantages that the medicine can treat both symptoms and root causes, has little side effects and a wide application range, and is obvious in blood sugar reducing effect, long in efficacy lasting effect and capable of stabilizing the blood sugar level of a diabetic.