Dendrobium officinale leaf extract with blood pressure reducing effect and application of dendrobium officinale leaf extract

A technology of dendrobium candidum and leaf extract, which is applied in the field of medicine, can solve the problems of common food use, and achieve the effect of reducing waste

Inactive Publication Date: 2015-07-01
ZHEJIANG CHINESE MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Dendrobium officinale Kimura et Migo recorded in the Chinese Pharmacopoeia is dry The stem, the leaf of Dendrobium candidum, does not belong to medicinal parts, nor can it be used as ordinary food; but the yield is large. Studies have shown that the leaves of Dendrobium candidum and the medicinal materials (stems) of Dendrobium candidum contain many similar chemical components, and some of them are similar function, but the current huge output of Dendrobium candidum leaves can only be used for waste treatment

Method used

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  • Dendrobium officinale leaf extract with blood pressure reducing effect and application of dendrobium officinale leaf extract
  • Dendrobium officinale leaf extract with blood pressure reducing effect and application of dendrobium officinale leaf extract
  • Dendrobium officinale leaf extract with blood pressure reducing effect and application of dendrobium officinale leaf extract

Examples

Experimental program
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Effect test

Embodiment 1

[0011] Dendrobium officinale leaves were washed and dried, crushed mechanically, refluxed and extracted with 10 times the amount of 30% ethanol for 3 times, each time for 1 hour, combined filtrates, concentrated under reduced pressure, recovered ethanol, and obtained Dendrobium officinale leaf extract.

Embodiment 2

[0013] Dendrobium officinale leaves were washed and dried, mechanically pulverized, refluxed with 15 times the amount of water to extract twice, each time for 2 hours, combined filtrates, concentrated under reduced pressure to obtain Dendrobium officinale leaf extract.

Embodiment 3

[0015] Dendrobium officinale leaves were washed and dried, crushed mechanically, refluxed with 20 times the amount of 15% ethanol for 3 hours each time, combined filtrates, concentrated under reduced pressure, recovered ethanol, and obtained Dendrobium officinale leaf extract.

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Abstract

The invention discloses a dendrobium officinale leaf extract with blood pressure reducing effect and application of the dendrobium officinale leaf extract. The dendrobium officinale leaf extract is prepared through the following steps: cleaning and drying the dendrobium officinale leaves; mechanically pulverizing; carrying out reflux extraction by a 0-30V% ethanol solution for 1-3 times, wherein the time of each reflux extraction is 1-3h and the dosage of each reflux extraction is 5-20 times of the medicine weight; combining the filtrates; recovering the ethanol; and carrying out vacuum concentration to obtain the dendrobium officinale leaf extract. The dendrobium officinale leaf extract can be used for preventing medicines or food for preventing and treating hypertension; the dendrobium officinale leaf extract relies on the dendrobium officinale leaves to develop the effects of the dendrobium officinale leaves, so that the new medicinal resources of the dendrobium officinale are expanded and the resource waste is decreased at the same time.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to the preparation of a dendrobium officinale leaf extract with antihypertensive effect and its application in preventing and treating hypertension. Background technique [0002] Hypertension (Hypertention) is a clinical comprehensive disease mainly manifested by increased systemic circulation pressure, and it is also an independent risk factor for cardiovascular diseases such as atherosclerosis and congestive heart failure. Hypertension is one of the most common cardiovascular diseases. At present, the prevalence of hypertension in my country's residents aged ≥18 is 18.8%. The number of patients in the country exceeds 160 million, and it is growing rapidly, requiring long-term treatment. The continuous development and deterioration of high blood pressure will lead to a series of heart, brain, kidney, and eye organ complications. Among them, stroke is the most serious ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8984A61P9/12A23L1/30A61K127/00
Inventor 吕圭源陈素红胡秀雷珊珊
Owner ZHEJIANG CHINESE MEDICAL UNIVERSITY
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