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A kind of clover root polysaccharide with antipyretic and anti-inflammatory effect and its application

An anti-inflammatory effect, the technology of cloverleaf, applied in the field of medicine, can solve the problem that there is no report on the antipyretic and anti-inflammatory effect of cloverleaf polysaccharide, and achieve a significant antipyretic and anti-inflammatory effect

Active Publication Date: 2017-08-18
ZHEJIANG CHINESE MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although it has been reported in the literature that the extract of Clover has antipyretic, analgesic and anti-inflammatory effects, there is no report on whether the polysaccharides of Clover have antipyretic and anti-inflammatory effects

Method used

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  • A kind of clover root polysaccharide with antipyretic and anti-inflammatory effect and its application
  • A kind of clover root polysaccharide with antipyretic and anti-inflammatory effect and its application
  • A kind of clover root polysaccharide with antipyretic and anti-inflammatory effect and its application

Examples

Experimental program
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Effect test

Embodiment

[0024] Preparation of trifolium root polysaccharide with antipyretic and anti-inflammatory effects:

[0025] (1) Preparation of crude polysaccharides from Pseudomonas clover root: Take Pseudomonas clover root and dry it in an oven at 35-65°C, dry it to a constant weight and then pulverize it, mix the pulverized product with double distilled water according to the ratio of 1g: 20mL of material to liquid, and heat to reflux Extract 3 times, 1h each time. After filtration, the extracts were combined for 3 times, concentrated by distillation under reduced pressure, 3 times the volume of 95% ethanol was added, after standing overnight, centrifuged at 4200rpm for 15min at high speed, the precipitate was dissolved in water, and then ethanol precipitation was carried out again, centrifuged to obtain the crude polysaccharides.

[0026] (2) Determination of crude polysaccharide content by phenol-sulfuric acid method:

[0027] ①Preparation of standard solution: D-glucose standard produ...

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Abstract

The invention discloses Tetrastigma hemsleyanum Diels et Gilg root tuber polysaccharide with anti-pyretic and anti-inflammatory functions and an application of the Tetrastigma hemsleyanum Diels et Gilg root tuber polysaccharide. The Tetrastigma hemsleyanum Diels et Gilg root tuber polysaccharide has remarkable anti-pyretic and anti-inflammatory functions, can be used for preparing anti-pyretic and anti-inflammatory drugs and has certain application value in prevention and control of diseases such as tumors, autoimmune diabetes, type 2 diabetes and the like always together with low fever and inflammation. The Tetrastigma hemsleyanum Diels et Gilg root tuber polysaccharide is prepared on the basis of the Tetrastigma hemsleyanum Diels et Gilg, the effects of the Tetrastigma hemsleyanum Diels et Gilg are developed, and the medicinal resource of the Tetrastigma hemsleyanum Diels et Gilg is expanded.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a trifolium root polysaccharide with antipyretic and anti-inflammatory effects and its application. Background technique [0002] Maintaining a constant body temperature is a necessary condition to ensure the normal progress of metabolism and life activities. Fever within a certain limit is a physiological defense response of the human body against diseases, but excessive body temperature or prolonged periods can cause various regulatory dysfunctions in the body and cause a series of metabolic and functional changes in the body. For example, fever can easily lead to dysfunction of the nervous system, which can make patients irritated, delirium, hallucinations, and even convulsions. This situation is more likely to occur in infants and young children. When the body temperature rises above 39°C, it is very easy to cause convulsions, and if the seizures occur repeatedly, the brain...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C08B37/00A61K31/715A61P29/00A61K36/48
CPCA61K31/715A61K36/48C08B37/00C08B37/0003
Inventor 丁志山钱朝东蒋福升黄燕芬郭菁菁代斌玲金波
Owner ZHEJIANG CHINESE MEDICAL UNIVERSITY
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