168results about How to "Improve biological effect" patented technology

The invention relates to a probiotic combination comprising different combinations of lactobacilli. propionic acid bacteria and/or bifidobacteria. The probiotics are preferably combined with a suitable prebiotic to form a synbiotic. The combination of the invention can be consumed as such or combined with a suitable foodstuff or pharmaceutical product, and it is therapeutically useful for example for stimulating the immune system and for general health improvement.

A novel liquid pesticide composition comprising a pesticidally active ingredient and a polyoxyethylene alkyl ether which has the following features (a) and (b): (a) an HLB value of 6 to 13.5; and (b) a content of 10 to 50 wt % based on the liquid pesticide composition.

The cap is made into pyramid shape, and made use of the thin permanent magnet iron flake with intensity magnetic field. It can strengthen the effect of the biological magnetism of the human body and strengthen the human brain with magnetic field. This is a new type and practicable cap.

This invention discloses reagents and methods for identifying peptides that modulate biological activities in cells, tissues, organs and organisms.

The invention provides a whitening composition inhibiting tyrosinase activities with multiple mechanisms and products of the composition, which relate to the field of chemicals for daily use. The whitening composition contains three active matters for inhibiting a tyrosinase active mechanism, and the three active matters include an active matter with competitive inhibition action, an active matter with noncompetitive inhibition action and an active matter with linear mixing competitive inhibition action. According to the invention, three inhibition mechanisms are used to obtain the novel inhibition composition, thus improving the enzyme inhibition efficacy of whitening effective substances and combinations, improving the biological effect of whitening, and reducing potential application irritation; the whitening composition is wide in coverage and relatively high in applicability, and has good whitening and freckle removing effects; and the whitening composition can be designed into essence, day cream, night cream, facial masks, facial cleansing milk and like products among cosmetic products.

A highly compact, high-performance volumetric imaging system is proposed, that is integrated with a multi-source Cobalt-60 gamma irradiator for high throughput, high accuracy and minimally invasive fractioned treatments of intracranial, orbital and head-and-neck targets.

A bioactive substance for conditioning human constitution and regulating immunity is prepared from cordyceps through extracting, filtering, concentrating, evaporating, spray drying, high-speed centrifugal filtering or diatomite filtering, and loading in capsules or preparing wine or oral liquid.

The invention relates to application of resveratrol-loading human multipotential stem cell exosome in preparing a drug for treating refractory healing skin wound related diseases. Compared with the prior art, embryonic stem cells and exosome inducing a human multipotential stem cell source are used as a drug carrier of the resveratrol, so that the biological effect of the resveratrol can be greatly improved; and by combining the function of the human multipotential stem cell exosome, the effect for treating the refractory healing skin wound related diseases can be greatly improved.

The invention discloses a preparing method of an efficient straw decomposition agent, and belongs to the technical field of decomposition agent preparation. The preparing method includes the steps that thalli in rotted wood where mushroom grows are selected, enrichment culture is carried out on the thalli to obtain bacterium liquid, trichoderma atroviride microbial inoculum, bacillus subtilis microbial inoculum, saccharomyces cerevisiae microbial inoculum and bacillus thuringiensis microbial inoculum are activated on a slope, fermentation media are inoculated with the microbial inoculums and fermentation culture is performed respectively, all strain fermentation liquids are mixed to obtain a mixed fermentation liquid, the mixed fermentation liquid and the bacterium liquid are mixed and then concentrated, and an adsorbing carrier and the concentrated liquid are mixed to prepare the efficient decomposition agent. The prepared straw decomposition agent is high in decomposition speed and capable of completely degrading straw, promoting release of straw nutrient, improving the fertility improvement effect of soil with straw returning and improving the biological effect.

The invention relates to a compound amino acid capsule (8-11) and a preparation method thereof, specifically to a capsule including pellets of eight amino acids and eleven vitamins and a preparation method thereof. The capsule comprises 7 spherical pellets which are composed of the following raw materials by weight: 2.66 to 9.9 parts of a thiamine mononitrate pellet, 16.35 to 20.5 parts of a vitamin pellet a, 35.0 to 44.1 parts of an amino acid pellet a, 11.4 to 14.4 parts of a vitamin pellet b, 6.65 to 10.5 parts of an amino acid pellet b, 12. 73 to 16.0 parts of a vitamin C pellet and 5.7 to 9.36 parts of a vitamin AD bead. The capsule provided by the invention has the advantages of a scientific and reasonable ratio, good stability, no toxic and side effects, high security and good biological effects and can be applied in preparation of medicines used for treating chronic liver and kidney diseases and of foodstuffs used for alleviating and eliminating physical fatigue caused by exercise training. The capsule provided by the invention has characteristics superior to those of the prior art.

The invention relates to the technical field of biology, and provides an isolated culture method as well as freeze storage and recovery method of mesenchymal stem cells. The isolated culture method ofthe mesenchymal stem cell comprises the following steps: acquiring a primary cell of the mesenchymal stem cell; performing the culture amplification for the primary cell of the mesenchymal stem cell;and isolating the mesenchymal stem cell. By adopting the isolated culture method of the mesenchymal stem cell, the mesenchymal stem cell with good cell quality, safety and biological effect can be obtained. For the mesenchymal stem cell obtained by the isolated culture method of the mesenchymal stem cell, the invention also provides a freeze storage and recovery method of the mesenchymal stem cell, so that the mesenchymal stem cell can be well stored and recovered.

The invention relates to a human pluripotent stem cell exosome loaded with resveratrol, and a preparation method and an application thereof. The invention provides the following applications of a human pluripotent stem cell exosome and the human pluripotent stem cell exosome loaded with resveratrol: an application in preparation of medicines or cosmetics for preventing stretch marks, repairing stretch marks or treating stretch marks, an application in preparation of skin anti-aging medicines or cosmetics, and an application in preparation of medicines or cosmetics for treating skin scars, skinfreckles, pox, pimples, acne and the like. Compared with the prior art, the exosome derived from embryonic stem cells and induced human pluripotent stem cells is used as a drug carrier of resveratrol, the biological effect of resveratrol can be greatly improved, and with combination of the self function of the human pluripotent stem cell exosome, a better therapeutic effect on diseases can be played.

The invention discloses herbal tea containing L-arabinose. The herbal tea comprises the following ingredients according to weight percent: 0.002%-10% of L-arabinose, 0.02%-3% of D-xylose, 0.2%-8% of stachyose, 0-15% of cane sugar and 64%-99.773% of pure water, and a proper quantity of food additives can be further added into the herbal tea. The herbal tea can regulate blood sugar level, reduce blood fat and relieve lipogenesis, solves the problem that the conventional herbal tea with high sugar and heat and low nutrition is not suitable for people wth diabetes, adiposis and the like, has a function of gut purging to solve the problems of constipation and toxin accumulation of people, can further dispel the effects of alcohol to protect the liver so as to solve the problem that the liver is damaged as people drink too much alcohol, and therefore, the herbal tea is healthy food for preventing diabetes, loosing weight, relaxing the bowels and protecting liver.

A cationic liposome is proportionally prepared from DOPE, DOTMA and cholesterol and can be used to encapsulate the object (adenovirus carrier) to obtain a recombinant human endostatin adenovirus-cationic liposome composition carrying the active antineoplastic genes for suppressing the growth of tumor. Its preparing process is also disclosed.

The invention discloses a biodegradable strontium-doped calcium sulfate material having biological activity, and its preparation method and use. The preparation method comprises the following steps of mixing a solution containing Ca<2+> and Sr<2+> and a sodium dodecanesulphonate solution, dropwisely adding the mixed solution into an inorganic salt solution containing SO4<2-> continuously subjected to ultrasonic and stirring treatment so that strontium-doped calcium sulfate dehydrate particles are precipitated, carrying out filtration, washing and drying of the strontium-doped calcium sulfate dehydrate particles, heating at a temperature of 150 to 170 DEG C to obtain strontium-doped alpha-calcium sulfate hemihydrate particles, mixing the strontium-doped alpha-calcium sulfate hemihydrate particles and normal saline into paste according to a solid/liquid ratio of 0.5-2.0, and carrying out a hydration reaction and solidification formation process. The biodegradable strontium-doped calcium sulfate material having biological activity can be continuously degraded and release calcium, strontium and sulfate ions in a bone injury, and is suitable for drug slow release and healing of various human bone and tooth injuries. The preparation method has the characteristics of simple processes, and good controllability of particle morphology, particle sizes and a strontium doping ratio.

The invention discloses an enrichment method of platelet cell factor concentrates. The method comprises the steps as follows: whole blood is taken, platelets are collected, a cell suspension is prepared with normal saline, subjected to ultrasonic crushing multiple times under the ultrasonic power of 100-200 W and crushed for 1-60 s each time, a crushed mixed solution is filtered, filtrate is taken, and the platelet cell factor concentrates are obtained. The obtained platelet ultrasonic lysates (cell factor concentrates) comprise TGF-beta, PDGF, IGFs, FGFs, EGF, VEGF and the like, have multiple bioactivities, can increase cartilage cell activity of organisms and promote stem cells to proliferate and differentiate and contributes to regeneration and repair of cartilages and bone tissue. The composition can be prepared in the form of injection, powder and the like and has excellent application prospects in the medical bone tissue engineering field.

The invention relates to medical technology field, discloses a glucocorticoid synergist, and is characterized in adopting total ginsenoside as synergist. Its proportions are respectively as following: total ginsenoside 200mg-1200mg and dexamethasone 0.75-187.5mg; total ginsenoside 200mg-1200mg and betamethason 0.75-187.5mg; total ginsenoside 200-1200mg, and prednisone 5-1250mg, total ginsenoside 200-1200mg, and precortisyl 5-1250mg; total ginsenoside 200mg-1200mg, and urbason 4-1000mg; total ginsenoside 200-1200mg, and cortisone 25-6250mg; and total ginsenoside 200-1200mg, and hydrocortisone 20-5000mg.Total ginsenoside as glucocorticoid synergist can be used in the treatment of diseases requiring long term or a large amount of glucocorticoid such as systemic lupus erythematosus, nephrotic syndrome, polymyositis, and rheumatoid arthritis.

The present invention provides humanized antibodies that immunospecifically recognize human α9 integrin. Some of these antibodies inhibit the biological functions of the α9 integrin, thereby exhibiting therapeutic effects on various disorders or diseases that are associated with α9 integrin, including cancer, e.g., the growth and metastasis of a cancer cell, and inflammatory diseases, e.g., rheumatoid arthritis, osteoarthritis, hepatitis, bronchial asthma, fibrosis, diabetes, arteriosclerosis, multiple sclerosis, granuloma, an inflammatory bowel disease (ulcerative colitis and Crohn's disease), an autoimmune disease, and so forth.

The invention relates to a conformal radiotherapy patch and a manufacturing method and application thereof. The conformal radiotherapy patch comprises a seal film, a support part, a protective material and a dosage monitoring and controlling device, wherein the support part is used for immobilizing radionuclides. The conformal radiotherapy patch is characterized in that the support part which immobilizes the radionuclides is sealed by the seal film and the protective material, the dosage monitoring and controlling device monitors and controls dosage of the radionuclides through pores of the protective material, a half-life period of the radionuclides is shorter than four days, and pure beta rays are adopted. Therefore, high compliance and conformality and short half-life period of the radionuclides are realized, continuous radiotherapy and precise monitoring and controlling are both achieved, and defects of existing radiopharmaceuticals in targeted continuous treatment and dosage control precision in treatment of skin diseases are improved.