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41results about How to "Inhibition of contractility" patented technology

Preparation method of fleshfingered citron fruit wine and product prepared by same

The invention discloses a preparation method of fleshfingered citron fruit wine and a product prepared by the same. The objective is to solve the problem that in the proportioning process of conventional fleshfingered citron fruit-citrus wine, two types of fruit juices in mixture have to be appropriate, otherwise the fermentation effect is poor and taste is not good, affecting the quality of wineafter fermentation. The method comprises the following steps: choice of materials, addition of yeast, pre-fermentation, post-fermentation and aging. Since the invention adopts fleshfingered citron fruits as a raw material to carry out fermentation to prepare the fruit wine, the problem of easy souring existing in conventional products is effectively avoided, the prepared fleshfingered citron fruitwine is purely sweet, and the quality of the wine is good. The fleshfingered citron fruit wine disclosed by the invention has the effects of inhibiting the intestinal smooth muscles, dilating the coronary vessels and increasing the blood flow of the coronary arteries, can also inhibit myocardial contractility, decrease the heart rate, decrease blood pressure and protect experimental myocardial ischemia, and also has the effects of relieving asthma and eliminating phlegm. The invention innovatively uses fleshfingered citron fruits to be fermented alone under the natural condition to prepare the wine, so that the nutritional value in the fleshfingered citron fruits is sufficiently exerted, so that the invention is a major innovation for fleshfingered citron fruit wine.
Owner:绵阳乾九和农业科技有限公司

Castor oil modified emulsion for improving edge corrosion resistance of waterborne coating

The invention relates to castor oil modified emulsion for improving edge corrosion resistance of a waterborne coating. The castor oil modified emulsion for improving the edge corrosion resistance of the waterborne coating is obtained by core-shell emulsion polymerization of core monomer pre-emulsion and shell monomer pre-emulsion, a castor oil modified monomer is added in the shell monomer pre-emulsion, and the formula of the castor oil modified monomer comprises 38.96% to 65% of castor oil, 5.96% to 22.16% of isocyanate acrylate, 23.70% to 48.90% of acetone, 0.19% to 0.65% of an organic tin catalyst, and 0.0019% to 0.0065 % of a polymerization inhibitor, and the components are condensed and vacuum removal of acetone is carried out to obtain the castor oil modified monomer. The castor oil modified emulsion for improving the edge corrosion resistance of the waterborne coating disclosed by the invention increases the reactivity of the castor oil, microgel is synthesized through a manner of the core-shell emulsion polymerization, and when the microgel is used in the waterborne coating, a triglyceride structure of the castor oil is better exposed on the surfaces of latex particles in a shell part of the emulsion, furthermore, the triglyceride structure obviously inhibits film shrinkage, and improves the edge corrosion resistance of the film in the solidification process of the film.
Owner:HAOLISEN CHEM TECH (JIANGSU) CO LTD

Vibrating diaphragm base material, preparation method thereof, vibrating diaphragm and loudspeaker

The invention discloses a vibrating diaphragm base material, a preparation method thereof, a vibrating diaphragm and a loudspeaker. the vibrating diaphragm base material comprises a first bonding layer, a second bonding layer, a first high polymer material layer made of a high polymer material, a second high polymer material layer made of a high polymer material and a porous damping material layermade of a porous damping material; the porous damping material layer is provided with a first side surface and a second side surface which are arranged back to back, the first high polymer material layer is bonded on the first side surface through the first bonding layer, and the second high polymer material layer is bonded on the second side surface through the second bonding layer. The vibrating diaphragm base material has the beneficial effects that (1) the size of a product prepared from the vibrating diaphragm base material can be kept consistent; and (2) the vibrating diaphragm base material can inhibit and improve the variation of the performance of a high polymer material under a high-temperature condition, so that the amplitude of a loudspeaker and other products adopting the vibrating diaphragm base material is slightly deviated along with the temperature rise, and the stability of the performance of the product is improved.
Owner:AAC TECH PTE LTD

Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of disorders related thereto

ActiveUS20190292196A1Lower performance requirementsImproves contractile function and hemodynamic statusOrganic active ingredientsOrganic chemistryLeft ventricular sizeKidney
The present invention relates to compounds of Formula (Ia) and pharmaceutical compositions thereof that modulate the activity of the beta-3 adrenergic receptor. Compounds of the present invention and pharmaceutical compositions thereof are directed to methods useful in the treatment of a beta-3 adrenergic receptor-mediated disorder, such as, heart failure; cardiac performance in heart failure; mortality, reinfarction, and / or hospitalization in connection with heart failure; acute heart failure; acute decompensated heart failure; congestive heart failure; severe congestive heart failure; organ damage associated with heart failure (e.g., kidney damage or failure, heart valve problems, heart rhythm problems, and / or liver damage); heart failure due to left ventricular dysfunction; heart failure with normal ejection fraction; cardiovascular mortality following myocardial infarction; cardiovascular mortality in patients with left ventricular failure or left ventricular dysfunction; left ventricular failure; left ventricular dysfunction; class II heart failure using the New York Heart Association (NYHA) classification system; class III heart failure using the New York Heart Association (NYHA) classification system; class IV heart failure using the New York Heart Association (NYHA) classification system; LVEF<40% by radionuclide ventriculography; LVEF≤35% by echocardiography or ventricular contrast angiography; and conditions related thereto.
Owner:ARENA PHARMA

Glass heat isolation water-based paint and preparation method thereof

The invention discloses glass heat isolation water-based paint and a preparation method thereof. The glass heat isolation water-based paint comprises a raw material body, and further comprises graphene, a first additive and a second additive, wherein the graphene accounts for 0.01 to 5 percent of the raw material body by mass; and the total amount of the first additive and the second additive accounts for 0.1 to 7 percent of the raw material body by mass. According to the glass heat isolation water-based paint and the preparation method thereof, the intensity of the glass heat isolation water-based paint is improved by adding of the graphene; by the use of the high heat conduction function of the graphene, the shortcoming that the heat accumulation temperature on the surface of glass coated with the existing heat absorption type glass heat isolation paint is high is overcome; furthermore, the friction resistance of the water-based paint, the bonding strength with a base material and the impact resistance are obviously improved; and the paint has obvious hydrophobic self-cleaning and heat isolation functions, can meet the environment-friendly development trend and the requirement, and has a wide application prospect in the field of heat preservation and isolation of building window glass and automobile glass.
Owner:SHENZHEN UNIV

Medulla junci qi-regulating foot bathing powder and preparation method thereof

The invention provides medulla junci qi-regulating foot bathing powder and a preparation method of the medulla junci qi-regulating foot bathing powder. Each 35g of the medulla junci qi-regulating foot bathing powder is composed of 20g of traditional Chinese medicinal mixed powder and 15g of traditional Chinese medicinal mixed medicinal residues, the 20g of traditional Chinese medicinal mixed powder is composed of medulla junci, dried tangerine or orange peel, rhizoma cyperi, fructus akebiae, semen litchi, fructus citri sarcodactylis, pericarpium arecae, exocarpium citri grandis, semen canavaliae and rhizoma corydalis at the ratio of 10: (5-8): (4-7): (4-6): (3-5): (2-4): (2-3): (1-3): (2-3): (1-2), and the 15g of traditional Chinese medicinal mixed medicinal residues are obtained after the raw materials in the 20g of traditional Chinese medicinal mixed powder are processed. The preparation method comprises the following steps: (1) carrying out pretreatment on the raw materials; (2) carrying out ultrasonic extraction; (3) carrying out concentrating and drying; and (4) carrying out grinding and sterilizing. For the medulla junci qi-regulating foot bathing powder and the preparation method of the medulla junci qi-regulating foot bathing powder, the preparation process is concise and scientific, and the prepared foot bathing powder is convenient to use and obvious in curative effects, and has the good qi regulating efficiency.
Owner:HARBIN LINGCAOSHU BIOLOGICAL TECH

Chinese medicine for treating angina pectoris and preventing from cerebral blood vessels and its preparation method

The invention discloses a traditional Chinese medicine for treating coronary heart disease angina pectoris and preventing and treating cerebrovascular accident diseases and its processing technology, which belongs to the technical field of traditional Chinese medicine. It is composed of the following raw materials according to the weight ratio: (150-450): (400-800): (0.3-3): (10-50). In the present invention, Panax notoginseng promotes blood circulation and removes blood stasis as the king, American ginseng tonifies deficiency, strengthens the body and benefits camp as the subject, reduces fragrance, regulates qi and promotes blood stasis, enhances Sanqi, activates blood circulation and removes blood stasis as assistant, and dipterocarp introduces various medicines into the whole body as the envoy; the medicines are simple but not complicated However, the monarch, the minister, the assistant and the envoy are all-round, attacking and supplementing and applying double entendres; it is suitable for both treatment and health care, and the medicine tastes mild, and it can be used by both sexes with cold and heat; it has high curative effect, low medicine cost, easy to take, and the medicine has no side effects and no contraindications. , safe and reliable, easy to grasp and use, and also has the characteristics of quick onset and short course of treatment, and the effective rate can reach 98%.
Owner:刘国英

Anti-deformation embedded block and mold shell forming method with flat bottom plate

The invention discloses an anti-deformation embedded block and a forming method for a mold case with a flat bottom plate. The anti-deformation embedded block used for forming a wax mold bottom plate of a single crystal directional vane module comprises a round plate with a flat outer surface, and the round plate is used for being embedded in a wax mold bottom plate forming mold to form a flat forming surface of the wax mold bottom plate. A flowing hole which is throughout a plate body of the round plate and used for mutual flowing of wax materials in an upper cavity and a lower cavity of the round plate and deformation resistance in the solidification process of the wax materials is formed in the round plate. The round plate is further provided with a positioning part used for positioning the round plate when the round plate is embedded in the wax mold bottom plate forming mold. The deformation of the wax mold in the solidification process of the wax materials can be effectively inhibited, deformation of the wax mold caused by surface tension of slurry in the case making process can also be inhibited, and the anti-deformation embedded block and the forming method for the mold case with the flat bottom plate are suitable for single crystal directional vane investment pattern precision casting of various aero-engines and industrial gas turbines.
Owner:CHINA HANGFA SOUTH IND CO LTD
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