10results about How to "Regulate immune function" patented technology

The application belongs to the technical field of biological medicine, and discloses application of high galangal polysaccharide in preparation of a preparation for improving alcohol-induced intestinal flora disorder. The application prepares an oral preparation with high galangal polysaccharide as an active ingredient, and aims at alcohol-induced intestinal flora disorder. According to a dosing amount of 125-250 mg / kg body weight / day, the alcohol-induced intestinal barrier damage can be repaired, the expression of tight junction proteins can be up-regulated, the intestinal flora alpha diversity can be improved, the intestinal flora structure can be regulated, the relative abundance of beneficial bacteria can be up-regulated, the relative abundance of harmful bacteria can be down-regulated, the alcohol-induced flora structure deviation can be reversed, and the intestinal short-chain fatty acid content can be increased, so that the alcohol-induced intestinal flora disorder can be well regulated.

The invention discloses a traditional Chinese medicine tea drink for preventing and treating oral mucosa diseases and a preparation method of the traditional Chinese medicine tea drink. The traditional Chinese medicine tea drink is prepared from 10-15 parts of radix astragali, 8-12 parts of radix codonopsis, 6-10 parts of radix salviae miltiorrhizae, 5-9 parts of radix angelicae sinensis, 3-6 parts of fructus psoraleae, 6-9 parts of rhizoma polygonati, 6-9 parts of radix adenophorae, 6-10 parts of rhizoma atractylodis macrocephalae, 5-9 parts of radix ophiopogonis, 3-5 parts of radix glycyrrhizae, 4-6 parts of pericarpium citri reticulatae and 5-8 parts of herba taraxaci. Aiming at the core pathogenesis of low immunity, long-term deficiency, long-term deficiency and kidney-yang insufficiency of patients suffering from oral mucosa diseases, qi tonifying, blood activating and kidney-qi strengthening are taken as a core treatment method, the formula is scientific and reasonable, all the medicinal materials act synergistically, the overall immune function of the body is adjusted, T lymphocyte subpopulation imbalance and cell factor network disorder are improved, and the curative effect is good. The oral mucosa microcirculation is improved, local inflammation is relieved, the immunity of a patient is improved fundamentally, the recurrence rate of oral mucosa diseases is reduced, and the problems that an existing tea drink is not high in pertinence and limited in curative effect are solved. The tea drink is appropriate in taste, good in compliance, high in safety and suitable for people with various oral mucosa diseases and low immunity.

The invention belongs to the technical field of medical preparations, and particularly relates to a resveratrol-succinyl glycan-tetravalent platinum nano-drug as well as a preparation method and application of the resveratrol-succinyl glycan-tetravalent platinum nano-drug. In the resveratrol-succinyl glycan-tetravalent platinum nano-drug provided by the invention, the succinyl glycan (RIC) can exert the anti-tumor activity by improving the immune function of a body; resveratrol (RES) can be used for directly acting on related targets and the like to exert anti-tumor activity by inhibiting proliferation of tumor cells, inducing apoptosis of the tumor cells, inhibiting invasion and metastasis of the tumor cells and regulating the immune function of a body. According to the invention, the succinylglycan-tetravalent platinum conjugate is used for wrapping an anti-cancer drug micromolecule RES, so that the anti-cancer curative effect of the drug is improved, the problems of toxic and side effects of platinum drugs, drug resistance of tumor cells and the like are solved, and a new idea is provided for construction and application of platinum nano-drugs.

The invention discloses a compound traditional Chinese medicine preparation for improving tumor immunity and resisting tumors, belongs to the technical field of anti-tumor traditional Chinese medicines, and discloses a compound traditional Chinese medicine preparation for improving tumor immunity and resisting tumors. The traditional Chinese medicine composition comprises the following components in parts by weight: 10-25 parts of ginseng, 15-18 parts of selfheal, 12-18 parts of seaweed, 12-19 parts of astragalus membranaceus, 10-16 parts of angelica sinensis, 18-30 parts of oldenlandia diffusa, 10-15 parts of fleece-flower root, 10-14 parts of poria cocos, 10-16 parts of thunberg fritillary bulb, 8-14 parts of pseudobulbus cremastrae seu pleiones and 8-17 parts of curcuma zedoary. Through the specific pharmacological action, growth and proliferation of thyroid tumor cells are inhibited, the development speed of tumors can be slowed down, the malignancy degree of the tumors can be reduced, apoptosis of the thyroid tumor cells can be induced, and the number of the tumor cells can be effectively reduced by inducing apoptosis of the tumor cells, so that the anti-tumor purpose is achieved.

The invention provides a traditional Chinese medicine composition for treating exogenous headache and a preparation method thereof, and belongs to the technical field of traditional Chinese medicinal materials. The traditional Chinese medicine raw material formula contains 6-20 parts by weight of radix puerariae, 1-5 parts by weight of fructus viticis, 1-5 parts by weight of rhizoma corydalis, 4-16 parts by weight of mint, 4-20 parts by weight of ligusticum wallichii, 4-20 parts by weight of schizonepeta, 1-5 parts by weight of asarum, 1-10 parts by weight of radix saposhnikoviae, 3-10 parts by weight of radix angelicae, 3-10 parts by weight of notopterygium root and 3-10 parts by weight of honey-fried licorice root. Traditional medicine believes that headache is mainly caused by internal organ dysfunction due to wind-cold damp evil invasion, emotion depression, improper diet and the like, exogenous evil invading brain collaterals, blood stasis and stagnation, and pain due to obstruction. The disease is treated according to the principle of dispelling wind, relieving pain and promoting blood circulation to remove blood stasis. The traditional Chinese medicine composition prepared by the method disclosed by the invention can dispel wind, dredge collaterals, dispel cold, eliminate dampness, clear head and eyes, promote qi circulation and relieve pain by matching the 11 traditional Chinese medicines.

The invention discloses a traditional Chinese medicine composition for treating glaucoma and a preparation method thereof, and relates to the technical field of traditional Chinese medicine preparations. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 5 to 15 parts of fructus lycii, 2 to 10 parts of flos chrysanthemi, 5 to 15 parts of radix rehmanniae recen, 2 to 10 parts of fructus corni, 5 to 15 parts of rhizoma dioscoreae, 5 to 15 parts of poria cocos, 2 to 10 parts of cortex moutan, 2 to 10 parts of salted rhizoma alismatis, 2 to 10 parts of lucid ganoderma, 2 to 10 parts of fried fructus broussonetiae and 2 to 10 parts of rhizoma acori graminei. The traditional Chinese medicine composition has the effects of nourishing kidney and liver, nourishing yin and promoting salivation, clearing liver and improving vision, and promoting qi circulation and inducing diuresis, and is used for treating blurred vision, eye swelling and pain and uncomfortable eyes caused by glaucoma.

The invention discloses a liver and stomach mixture capable of reducing gastrointestinal injury and a preparation method of the liver and stomach mixture, and relates to the technical field of traditional Chinese medicines. 60% of jack fruit peel; 10% of absolute ethyl alcohol; 8% of galacturonic acid; 5% of vitamin B; 5% of mycelium; and 12% of distilled water. The jackfruit peel, absolute ethyl alcohol, galacturonic acid, B vitamins, mycelia and other raw materials are matched to prepare the liver-stomach mixture, a layer of viscous anti-acid protective film is formed in the stomach and intestine after the liver-stomach mixture is drunk in advance, the mixture covers the gastrointestinal intima, rapid absorption of alcohol is retarded, 90% of alcohol is converted into harmless acetic acid, carbon dioxide and water, and the liver-stomach effect is improved. The vitamin B has the effect of resisting oxidation and can achieve the effects of supplementing body nutrition, relieving mental disorder, promoting metabolism and the like, the mycelium mainly has the effects of regulating the immune function, improving the respiratory function and resisting oxidation, and the protection effect on the human body is improved.

This invention discloses a combined acupuncture and medication method for treating cervicogenic vertigo, belonging to the field of traditional Chinese medicine clinical treatment technology. The method comprises two parts: oral administration of a specific herbal composition and standardized acupuncture knife therapy. The herbal composition consists of Pinellia ternata, Gastrodia elata, Uncaria rhynchophylla, Poria cocos, Citrus reticulata peel, stir-fried Atractylodes macrocephala, Zingiber officinale, Haliotis diversicolor, Pueraria lobata, Cinnamomum cassia, Corydalis yanhusuo, Ziziphus jujuba, Lycopodium clavatum, Spatholobus suberectus, Pheretima aspergillum, Chaenomeles speciosa, and Paeonia lactiflora in specific dosages, which are then sterilized, preserved, dried, pulverized, and sieved to form capsules for oral administration. The acupuncture knife therapy targets Baihui (GV20), the midpoint of the neck, the left point of the neck, the right point of the neck, and the articular process points. This invention has the effects of resolving phlegm and relieving wind, strengthening the spleen and removing dampness, calming liver yang, relieving exterior cold, and relaxing tendons and vessels, far exceeding the effects of Western medicine treatment alone. It is most effective for the phlegm-dampness obstruction type. It has the advantages of being safe with no side effects, treating both the symptoms and the root cause, having a low recurrence rate, a high degree of standardization, and a wide range of applications. It improves the pathological state of cervicogenic vertigo from the root, embodying the concept of preventive medicine in traditional Chinese medicine, and has significant clinical application value.

The invention relates to the field of medicines, in particular to a traditional Chinese medicine composition and a pharmacodynamic effect and an in-vivo anti-inflammatory effect of the traditional Chinese medicine composition in an anti-H3N2 influenza virus model. The traditional Chinese medicine composition provided by the invention has an inhibition effect on proliferation of influenza virus H3N2 in cells; the high dosage of the compound has an inhibition effect on the weight change, lung index and lung tissue virus titer of a mouse infected by the H3N2 virus, and has a better improvement effect on lung lesions caused by virus infection; a good inhibition effect on mouse ear swelling caused by medium and high doses of p-xylene is achieved; the pharmaceutical composition has a good intervention effect on prophylactic administration and therapeutic administration of LPS-induced mouse acute pneumonia, can effectively reduce lung indexes, improve lung pathology, inhibit inflammatory mediator level and IgM level and regulate T cell immune function, and has a good dose-effect relationship. In conclusion, the traditional Chinese medicine composition has an antagonistic effect and an anti-inflammatory effect on influenza virus, and has a good treatment prospect on influenza and complicated inflammation thereof clinically.

The present invention discloses a preparation method of Shenxianling granules, a traditional Chinese medicine preparation for treating digestive tract tumors, and its application, which relates to the technical field of traditional Chinese medicines, and comprises the following steps: (1) preparing materials; (2) dividing materials; (3) mixing materials; and (4) granulating. The active ingredients in the Shenxianling granules, a traditional Chinese medicine preparation prepared by the present invention, can directly or indirectly inhibit digestive tract tumor cells, and at the same time regulate the immune function of the body, inhibit the growth of digestive tract tumor cells, and have a good inhibitory effect.