59 results about "Gastrointestinal Injury" patented technology

Disclosed are nutritional compositions including human milk oligosaccharides that can be administered to individuals including preterm infants, infants, toddlers, children, and adults for preventing injury and / or improving the healing of the gastrointestinal tract. Additional suitable methods of using the nutritional compositions including the human milk oligosaccharides are also disclosed.

A nutritional supplement containing fish oil and selenium has been identified that potentiates radiotherapy of tumors in a synergistic fashion. Cotherapy with such a supplement and radiotherapy results in substantially improved reductions in tumor volume of animal models relative to radiotherapy alone, and reduces common side effects such as weight loss, inflammation, and damage to the gastrointestinal tract. Such cotherapy was also found to reduce the incidence of metastasis from the primary implantation site, and to modulate expression of genes associated with apoptosis in tumor cells. A formulation for such a supplement that is both well tolerated and palatable is also provided.

Disclosed are nutritional compositions including human milk oligosaccharides that can be administered to individuals including preterm infants, infants, toddlers, children, and adults for preventing injury and / or improving the healing of the gastrointestinal tract. Additional suitable methods of using the nutritional compositions including the human milk oligosaccharides are also disclosed.

The invention discloses a novel gas signal molecule donator and a preparation method and medical use thereof, in particular to a compound with new structure and the preparation method and medical use of the compound. The compound is a compound with a general formula YLXYII or the salt of the compound, comprises the portion related with hydrogen sulfide and is often combined with compounds in covalence mode or forms the salt. Pharmacological results show that the compound has remarkable anti-inflammatory effect and tumor resistance without remarkable damage to gastrointestinal tract, so that the compound can be used for preparing and treating various diseases such as inflammation, cardiovascular diseases, and diseases related with tumor. In addition, the preparation method for preparing the compound is further provided.

The invention relates to the use of a composition comprising extract of Buddleja globosa Hope and pharmacologically accepted excipients for the preparation of a phyto-pharmaceutical agent, a drug or a nutraceutical for the prevention of gastrointestinal disorders, particularly those associated with treatment with nitrofurantoin or gastric disorders produced by ulcers, gastric diseases or damage to the gastrointestinal tract. The aforementioned disorders can correspond to abdominal pain, dyspepsia, nausea, vomiting, diarrhea, constipation, inflammation and cephalalgia resulting from treatment with nitrofurantoin and other antimicrobials. In addition, the extract and the compositions thereof can be used to enhance the antibacterial action of nitrofurantoin, particularly against Escherichia coli.

The invention provides a traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from, by weight, 10-40 parts of sargentg loryvine stems, 10-40 parts of astragali radix and 10-40 parts of glossy privet fruit. The invention further provides a preparing method and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition is low in price, efficient, convenient, safe and capable of effectively reducing damage to the gastrointestinal tract and / or reduction of peripheral blood lymphocytes caused by chemotherapy drugs.

The invention discloses the application of Codonopsis oligosaccharides in the preparation of drugs for preventing or treating gastrointestinal injury caused by hypoxia, the hypoxia being plateau hypoxia and / or tissue ischemic hypoxia; Methods for the preparation of polysaccharides. The beneficial effects of the present invention are: the application of Codonopsis oligosaccharides provided by the present invention in the preparation of drugs for preventing or treating gastrointestinal damage caused by hypoxia, the prepared drugs have good effects, and the drugs themselves Safe and effective, without toxic and side effects; it has been verified by experiments that drugs containing Codonopsis oligosaccharides can improve spleen atrophy and lung enlargement caused by high-altitude hypoxia in rats, enhance their antioxidant levels, improve inflammation, and relieve intestinal mucosal damage. Reducing EPO expression, and protein expression detection further indicated that Codonopsis oligosaccharides can reduce the expression of HIF-1α in the duodenum of high-altitude hypoxic rats.