64 results about "Gastric Disorders" patented technology

A device, system and method for diagnosing and treating gastric disorders is provided. A functional device resides within the patient's stomach and is secured to the stomach wall by an attachment device. The functional device may be a sensor for sensing various parameters of the stomach or stomach environment, or may be a therapeutic delivery device. The functional device in one embodiment provides a device, system and method for gastric electrical stimulation where stimulating electrodes are secured to the wall of the stomach by the attachment device or otherwise. A preferred device includes: at least one stimulating electrode in electrical contact with the stomach wall; an electronics unit containing the electronic circuitry of the device; and an attachment mechanism for attaching the device to the stomach wall. The functional devices may be programmed to respond to sensed information or signals. An endoscopic delivery system delivers the functional device through the esophagus and into the stomach where it is attached the stomach wall. The endoscopic instruments attach or remove the attachment devices and functional devices from the stomach and may be used to assist in determining the optimal attachment location.

Improved efficacy in treatment of gastric disorders with botulinum toxin is obtained using liposomal encapsulated botulinum formulations for topical administration of the botulinum toxin. The liposomes are typically administered in a physiologically acceptable carrier such as saline or phosphate buffered saline by application onto the surface of the tissue within into the gastrointestinal (GI) tract in need of treatment. Preferably, the formulation is applied via a roller, sponge or nozzle that is attached to an endoscope.

Methods and compositions are disclosed utilizing optically pure (−) pantoprazole for the treatment of ulcers in humans while substantially reducing the concomitant liability of adverse effects associated with the racemic mixture of pantoprazole. The optically pure (−) isomer is also useful for the treatment of gastroesophageal reflux. (−) Pantoprazole is an inhibitor of H⁺ release and is therefore useful in the treatment of other conditions related to gastric hypersecretion such as Zollinger-Ellison Syndrome.

A device, system and method for diagnosing and treating gastric disorders is provided. A submucosal gastric implant device is placed within the submucosal layer of a patient's stomach wall. The device in one embodiment provides electrical stimulation of the stomach wall and may use multiple electrode pairs for sequential stimulation. The device may also have other functional aspects such as a sensor for sensing various parameters of the stomach or stomach environment, or a therapeutic delivery device. The implant may be programmed to respond to sensed information or signals. The device may be modular with a portion of the device accessible outside the stomach wall for removal and replacement. An endoscopic delivery system prepares and delivers the functional device through the esophagus and into the stomach where it is placed through an opening in the mucosa into the submucosal layer of the stomach wall. The endoscopic instruments may be used to prepare a cavity in the submucosal layer of the stomach wall and deliver the device to the prepared cavity and if appropriate close the opening in the mucosa.

The invention relates to a multi-label stomach disease classification method and device based on a medical record text, and belongs to the technical field of medical text intelligent processing. The method comprises the steps that multiple sets of training data are acquired, and each set of training data comprises the medical record text and a disease label corresponding to the medical record text; training a preset network structure based on the multiple groups of training data to obtain a disease classification model; using the disease classification model for identifying disease classification in the input medical record text, wherein the network structure is a combination of a pre-training model and a seq2seq model; and converting a multi-label classification problem into a sequence generation problem by utilizing a network of a pre-training model and a self-attention mechanism, so that very good multi-label classification performance is obtained on limited training samples. Besides, manual participation is not needed in the classification process, human factors are reduced, meanwhile, accurate diagnosis reference can be provided for doctors, and the working pressure of medical staff is relieved.

The present invention is Chinese medicine granule for treating cardiac and cerebral diseases and its preparation process. The medicine is prepared with wheat, kudzuvine root, date, licorice and ginkgo leaf extract, and the preparation process includes twice decoction of wheat, kudzuvine root, date and licorice, filtering, merging filtrate, concentration, spray drying, mixing with ginkgo leaf extract, cane sugar and dextrin, pelletizing and other steps. The Chinese medicine granule has the functions of tranquilizing, relieving the gastric disorder and relaxing joints and muscles, and is used in treating depression, neurasthenia and climacteric syndrome.

The invention discloses a gastric mucosa cleanliness evaluation method and system based on deep learning. The method comprises the following steps: acquiring a gastroscope video frame in real time; performing cleanliness evaluation frame by frame based on a pre-constructed gastric mucosa cleanliness evaluation model; wherein a method for creating the gastric mucosa cleanliness evaluation model comprises the following steps of acquiring a gastroscope training image set; marking and scoring each training image according to a preset gastroscope cleanliness evaluation system; and training the gastric mucosa cleanliness evaluation model based on a deep learning network by adopting the training image set. The gastric mucosa cleanliness can be accurately evaluated, and a positive effect is achieved for diagnosis of gastric diseases and preparation and quality control before endoscopy.

The present invention belongs to the field of Chinese herbal medicine, and provides a kind of chronic gastropathy treating Chinese medicine. The Chinese medicine has the functions of invigorating Qi and spleen, warming stomach, nourishing Yin, clearing away heat, keeping the adverse energy downwards, relieving gastric disorder, regulating Qi, etc and is used in treating chronic erosive gastritis, chronic atrophic gastritis, gastric cavity fullness feeling, stomachache and other chronic gastropathy. The present invention has high effective rate.

The invention discloses lactobacillus casei for resisting helicobacter pylori and application thereof. The lactobacillus casei is preserved in the China General Microbiological Culture Collection Center, and the preservation number is CGMCC No. 21138. The lactobacillus casei strain grows well in a high-acid and high-cholate concentration environment, has high acid resistance and cholate resistance, has an obvious growth inhibition effect on helicobacter pylori, also has an obvious inhibition effect on helicobacter pylori adhering to human gastric mucosa GES-1 cells, and can inhibit in-vivo colonization of helicobacter pylori and relieve inflammation caused by pathogenic bacterium infection in animal experiments. The strain has wide application prospects in medicaments, functional products and health care products for preventing or treating gastric diseases caused by helicobacter pylori infection.

Improved efficacy in treatment of gastric disorders with botulinum toxin is obtained using liposomal encapsulated botulinum formulations for topical administration of the botulinum toxin. The liposomes are typically administered in a physiologically acceptable carrier such as saline or phosphate buffered saline by application onto the surface of the tissue within into the gastrointestinal (GI) tract in need of treatment. Preferably, the formulation is applied via a roller, sponge or nozzle that is attached to an endoscope.

The invention relates to the use of a composition comprising extract of Buddleja globosa Hope and pharmacologically accepted excipients for the preparation of a phyto-pharmaceutical agent, a drug or a nutraceutical for the prevention of gastrointestinal disorders, particularly those associated with treatment with nitrofurantoin or gastric disorders produced by ulcers, gastric diseases or damage to the gastrointestinal tract. The aforementioned disorders can correspond to abdominal pain, dyspepsia, nausea, vomiting, diarrhea, constipation, inflammation and cephalalgia resulting from treatment with nitrofurantoin and other antimicrobials. In addition, the extract and the compositions thereof can be used to enhance the antibacterial action of nitrofurantoin, particularly against Escherichia coli.

The invention belongs to the technical field of biological medicines, and discloses a stomach-targeted drug-loaded exosome and application thereof and a drug for treating gastric diseases so as to solve the problem that the treatment effect of an existing targeted preparation on gastric diseases is not obvious enough. The stomach-targeted drug-loaded exosome is obtained by introducing a drug for treating stomach diseases into an exosome with stomach tissue targeting property, and the exosome with stomach tissue targeting property is derived from pancreatic cells. The exosome secreted by the pancreatic cells can be enriched in the stomach without any modification, the exosome secreted by the pancreatic cells solves the problem of exosome yield and has a good application prospect; different drugs or active molecules can be loaded by the exosome secreted by the pancreatic cells; and through targeted stomach tissue administration, treatment effect on stomach diseases is improved, and toxic and side effects of medicines are reduced.

The invention discloses a chemiluminiscence detection kit for diagnosing gastropathy in a combined manner. The detection kit is mainly used for performing pepsinogen I detection and pepsinogen II detection. On the basis of the detection kit, the invention further provides a marker combined standard value, which is applicable to the detection kit and can provide reference for gastropathy detection, for detection. The detection kit has the advantages that the detection kit is wide in linearity range, high in specificity, convenient to operate, and the like in terms of gastropathy diagnosis and early gastric cancer screening; in addition, the detection kit is accurate and detailed in gastropathy diagnosis and high in market popularization value, and damage, caused by X-rays, on human bodies and the inconvenience of a gastroscope are avoided.

The invention discloses a method for producing a smokeless mosquito coil by taking cumin straw as a main raw material. The method comprises the following steps: firstly drying, dewatering and crushing the cumin straw, then proportionally mixing with an adsorbent, carbon powder, an adhesive and a pesticide, adding water, uniformly stirring, moulding, pressing a layer of graphene onto each of the two surfaces of a sheet-like substrate, drying and dewatering to obtain the smokeless mosquito coil. By taking the cumin straw powder as the main raw material, the obtained mosquito coil has special aroma, and can expel wind and cold, warm kidney, relieve the gastric disorder and regulate Qi; in order to prevent smoke generation in the electric heating process, the adsorbent is added into a formula provided by the invention, and the adsorbent can adsorb toxic gases and large particulate substances; moreover, through addition of graphene, smoke can be confined inside, and only a nano-sized effective substance of which the particle size is smaller than the pore size of the graphene can be released into air. The smokeless mosquito coil is not only low in cost, good in effect and harmless to a human body, but also uses a large amount of cumin straws, so that farmers are effectively prevented from burning the straw to cause environment pollution.

The invention discloses an application of rotala rotundifolia and an extract thereof in preparation of a medicine for treating gastrointestinal diseases and a medicine formula, the medicine formula contains rotala rotundifolia or the extract thereof, and the medicine formula also contains a Yunnan Baiyao YIKOUZHONG; the traditional Chinese medicine composition has a special effect on diminishing inflammation and sterilizing helicobacter pylori, effectively inhibits bacterial infection, prevents the helicobacter pylori from spreading in a human body from the source, can quickly treat gastric ulcer, antral gastritis, chronic gastritis, gastrectasia and other stomach diseases, has a special curative effect on constipation caused by ulcerative colitis, is low in cost, and quick in effect. The cure rate is more than 90%, and the relapse possibility is small.

The invention provides a compound Chinese herbal medicine capsule for treating and killing helicobacter pylori and a preparation method. The compound Chinese herbal medicine capsule is prepared from the following components by weight: 12 to 18g of common vladimiria root, 15 to 20g of cortex magnoliae officinalis, 15 to 21g of rhizoma galangae, 15 to 25g of fructus tsaoko, 20 to 25g of fructus amomi, 15 to 27g of rhizoma bletillae, 20 to 25g of cuttlebone and 10 to 15g of flos caryophylli. The compound Chinese herbal medicine capsule provided by the invention can be used for effectively killingcomplications including gastric acid, gastrectasia, stomachache, gastric ulcer, gastric erosion, emesis, dyspepsia and the like, caused by the helicobacter pylori, and also can be used for effectively killing the helicobacter pylori; the compound Chinese herbal medicine capsule has the advantage of treating both principal and secondary aspects of stomach diseases; the compound Chinese herbal medicine capsule has abundant medicine resources and sufficient renewable resources, can be used as food and medicines, has a rapid effect, high healing rate and small dosage, and does not cause recurrence after healing; and the effective rate is 98 percent and the healing rate is 85 percent or more.

The invention belongs to the medical field, and provides a stomach disease examining and diagnosing system. The system comprises at least one magnetic control system provided with a magnet, an image viewing server, at least one image viewing client side, wherein the magnetic control system is used for controlling the magnet to move according to control instructions of an operator to drive a capsule endoscope in the stomach of a subject, and the capsule endoscope collects stomach images and transmits the images to the image viewing server through the magnetic control system; the image viewing server communicates with the magnetic control system and is used for receiving and storing the stomach images; the image viewing client side communicates with the image viewing server and is used for reading the stomach images from the image viewing server and uploading a diagnosis report obtained by the stomach images to the image viewing server; the image viewing server is further used for feeding back the report to the magnetic control system, and the magnetic control system is further used for receiving the report fed back by the image viewing server. The problem that diagnosis doctors are distributed in regions unevenly to cause poor diagnosis effects is solved effectively.

The present invention relates to a health supplement food. More particularly, the present invention relates to a health supplement food prepared by mixing dried powders, wherein the dried powders include 5 to 15% by weight of black beans, 5 to 15% by weight of black sesame seeds, 5 to 15% by weight of corn, 5 to 15% by weight of adlay, 5 to 15% by weight of sorghum, 5 to 15% by weight of mulberry leaves, 5 to 15% by weight of mulberry fruits, 7 to 20% by weight of Polygonum multiflorum Thunberg, 5 to % by weight of dandelion, 1 to 10% by weight of licorice, 2 to 15% by weight of kelp, and 5 to 15% by weight of cactus based on solid content. The health supplement food may exhibit effects such as promotion of hair growth, alleviation and mitigation of hair loss, regulation of blood glucose, or alleviation and relief of gastric disorder symptoms.

The present disclosure provides means and methods for promoting gastric emptying. In particular, the present disclosure provides the use of insulin or a composition comprising same for promoting gastric emptying and for treating gastric disorders, particularly disorders characterized by delayed gastric emptying. The insulin or composition comprising same are to be administered enterally.

The invention discloses sweet potato powder capable of strengthening kidney, protecting stomach and clearing away lung-heat and a preparation method of the sweet potato powder. The sweet potato powder is prepared from the following components in parts by weight: 500-600 parts of sweet potato powder, 100-150 parts of Chinese yam, 100-150 parts of bighead atractylodes rhizome, 100-150 parts of fig, 80-100 parts of barley flour, 80-100 parts of oat flour and 80-100 parts of soybean flour. The preparation method comprises the following steps: step 1, pulping; step 2, extrusion forming; step 3, curing; step 4, aging; and 5, cutting to obtain the product provided by the invention. The sweet potato powder disclosed by the invention is beneficial for helping discharge of impurities and toxins in a body, enriching blood, tonifying kidney and relieving lumbago; the stomach protecting effect is excellent, stomach diseases such as gastritis and gastric ulcer can be treated, and the product is an ideal health-care product for patients with stomach diseases; and the sweet potato powder also has the effects of clearing heat, eliminating phlegm and relieving cough, and can relieve cough and fever symptoms.

The present invention belongs to the technical field of biology, and specifically discloses a preparation method and application of a urease activity inhibition yolk antibody. By use of gene recombination technology, helicobacter pylori urease (Urease) B subunit DNA fragment is cloned, and after base mutation, constructed and cloned on to a prokaryotic expression plasmid vector, genetic engineering strain BL21 (DE3) is transformed, IPTG is used for inducing expression of recombinant antigen protein urease B subunit, and a soluble form of expression can be successfully implemented; lysis of cells is performed, and urease B subunit recombinant protein can be isolated and purified; the purified recombinant protein urease B subunit as an antigen and an adjuvant are prepared into a microsphere vaccine for laying hen immunization, the yolk antibody in egg yolk can be extracted by pot group-type countercurrent extraction, and the yolk antibody titer and specificity can be detected by ELISA and other techniques. The obtained yolk antibody is added into milk for direct drinking for curing and prevention of acute and chronic gastritis, peptic ulcer and other stomach diseases caused by helicobacter pylori infection.

The invention provides an application of a rose odorata var gigantea fruit extract in preparation of medicine, health care product or food for treating and/or preventing stomach diseases. Experiments prove that the rose odorata var gigantea fruit extract has the effects of treating atrophic gastritis and repairing gastric mucosal lesion, and the curative effect is exact. The invention discloses a new application of the medicinal material rose odorata var gigantea fruit.