79 results about "Delta-gluconolactone" patented technology

The application belongs to the technical field of plant raw material processing, and particularly relates to a preparation method of a blocky emulsion gel product simulating animal fat, which is formed based on a soybean protein and sodium alginate composite base and comprises the following steps: (1) mixing pure water, soybean protein and sodium alginate, then shearing at high speed, and dispersing and emulsifying in perilla oil; (2) adding gluconolactone, stirring and mixing, then immediately adding calcium carbonate while stirring, to form a first gel network; (3) after stirring, pouring into a mold for shaping, placing in a 4 DEG C refrigerator for gelation, forming a second protein network, and obtaining a simulated fat product with strong stability. The application forms a simulated fat with a complex double-network structure under the action of two kinds of inducing agents by constructing a protein-polysaccharide composite gel system, improves the stability and oiliness of the gel, and expands the cooking adaptability of the simulated fat.

The invention discloses a staged delayed coagulation and viscosity reduction type iron aluminate cement water reducing agent and a preparation method thereof. The iron aluminate cement water reducing agent is obtained by copolymerizing prepared isopentenol polyoxyethylene ether borate, hydroxyethyl methylacrylate glucolactone and methacrylic acid. The boric acid ester is rapidly hydrolyzed in the initial stage of hydration (9 < pH < 12) to obtain boric acid, and first-stage delayed coagulation is performed on the aluminoferrite cement. When delayed coagulation fails, the cement continues to be hydrated to reach the middle stage of hydration (pH > 12), glucolactone is hydrolyzed to generate gluconate for further delayed coagulation of the cement, meanwhile, hydroxyethyl methylacrylate is hydrolyzed to release more adsorption sites, and hydration products are further dispersed to reduce the viscosity of the system. And stage release enables the aluminoferrite cement to be hydrated stage by stage, so that the problem of poor bleeding cohesiveness caused by non-hydration of the cement after one-time doping of the retarder is solved, the problem of slurry tackifying caused by large hydration of the cement in the later stage is also avoided, and engineering application of the aluminoferrite cement is further promoted.

The invention belongs to the technical field of biomedical materials, and discloses pH-responsive injectable hydrogel as well as a preparation method and application thereof. Comprising the following steps: (1) dissolving sodium alginate in water to form a uniform solution; (2) adding a fat-soluble small molecule drug and Fe3O4 nanoparticles into the solution, carrying out high-speed shearing dispersion under an ice-water bath condition to form a drug / nano composite system, and standing; and (3) sequentially adding a calcium carbonate suspension and glucolactone into the drug / nano composite system, uniformly stirring, and incubating until the mixture is completely cured to obtain the pH-responsive injectable hydrogel. The hydrogel obtained by the invention not only has excellent injectability and pH response release performance, but also can remarkably improve the loading efficiency of fat-soluble drugs, and provides a new technical approach for realizing local anti-tumor treatment.

The invention discloses a method for enhancing swelling resistance of noodles, and belongs to the technical field of food. According to the invention, noodles containing natural polysaccharides (sodium alginate, pectin and the like) are soaked in a solution containing glucolactone and calcium carbonate so as to promote the noodles to react, and a uniform gel barrier is formed on the surfaces / interiors of the noodles through slow and controllable in-situ crosslinking of the polysaccharides and calcium ions, so that the effects of inhibiting moisture permeation and reducing the swelling rate are achieved; finally, the anti-swelling noodles are prepared. Besides, the prepared anti-swelling noodles are moderate in hardness and more uniform in cross-linking after being cooked, have boiling fastness and shape retention, are relatively low in viscosity, are not sticky after being cooked, are free of bitter taste and peculiar smell, and are good in chewing taste, so that the anti-swelling noodles have wide market value and prospects in the technical field of foods.

The invention belongs to the technical field of medical biological materials, and particularly relates to a repair material for trigeminal nerve injury as well as a preparation method and application of the repair material. The repairing material is prepared from the following raw materials in parts by mass: 0.5 to 5 parts of nervous tissue acellular matrix micro powder, 0.5 to 5 parts of oxidized sodium alginate, 0.005 to 0.02 part of calcium dobesilate, 0.4 to 1 part of Ca-EDTA (Ethylene Diamine Tetraacetic Acid) and 0.4 to 1 part of D-glucolactone. The repairing material is directly injected to the exposed nerve part, damaged nerves are wrapped, the protection effect is achieved, external environment irritation is prevented, the components of the repairing material have the nerve nourishing effect, repairing of the damaged nerves can be promoted, permanent injury of trigeminal nerves is avoided, the duration time of related symptoms is shortened, and the repairing material has a good application prospect. Therefore, the method has good practical application value.

The invention provides an industrial cleaning agent and a preparation method thereof, and the cleaning agent is prepared from the following raw materials by weight: 0.05-0.1% of sodium hydroxide, 0.2-0.3% of sodium gluconate, 1-2% of secondary alkyl sodium sulfonate, 1.5-2% of polyol, 1-1.5% of amino trimethylene phosphonic acid, 0.3-0.6% of gluconic acid-delta-lactone, 0.6-1% of glycerin, 0.8-1.2% of propylene glycol butyl ether, 0.05-0.075% of a modified polyether defoamer, and the balance of water. And the balance of water. The modified polyether defoaming agent is obtained by sequentially reacting alkenyl polyether with # imgabs0 # and hydrogen-containing silicone oil. The cleaning agent provided by the invention has better defoaming effect, lower corrosivity and higher stability, and also has the advantages that the preparation method is simple and easy to operate, and the cleaning agent is suitable for large-scale industrial production.

The utility model discloses a glucolactone solution evaporation and concentration device which comprises a heating tank and a cooling tank, a liquid inlet pipe is arranged at the top of the heating tank, a first ball valve is arranged on the liquid inlet pipe, heating pipes which are symmetrically distributed are arranged on the inner bottom wall of the heating tank, and a centrifugal pump is arranged between the heating tank and the cooling tank. A liquid pumping pipe is fixedly connected between the liquid inlet end of the centrifugal pump and the heating tank, a conveying pipe is fixedly connected between the liquid outlet end of the centrifugal pump and the cooling tank, a cold water tank is arranged on one side of the cooling tank, a water pump is installed on the top of the cold water tank, a water cooling plate is installed on the inner bottom wall of the cooling tank, and the liquid inlet end of the water cooling plate is fixedly connected with the liquid outlet end of the water pump. The liquid outlet end of the water cooling plate is fixedly connected with the cold water tank, the liquid inlet end of the water pump is fixedly connected with a connecting pipe, and a first driving motor is fixedly mounted in the center of the top of the cooling tank; according to the invention, the solution can be rapidly cooled, the waiting time is reduced, subsequent treatment and use are facilitated, and the working efficiency is further improved.

The invention relates to the technical field of cleaning tablets, and provides a multi-effect cleaning tablet for a kitchen waste processor and a preparation method of the multi-effect cleaning tablet. The multi-effect cleaning tablet comprises a foaming cleaning layer, an oxidation sterilization layer and a deep decomposition layer, the foaming cleaning layer is arranged on one side of the oxidation sterilization layer, the deep decomposition layer is arranged on the opposite side of the oxidation sterilization layer, and the foaming cleaning layer comprises sodium bicarbonate, gluconic acid-delta-lactone, alkyl glycoside, limonene and a chelating agent; the oxidation sterilization layer comprises sodium percarbonate, potassium hydrogen peroxysulfate, potassium carbonate, sodium citrate and a stabilizer; the deep decomposition layer comprises biological enzyme. Gluconic acid-delta-lactone is adopted in the foaming cleaning layer of the multi-effect cleaning tablet to generate gluconic acid, so that the system is prevented from instantly and violently turning over, a middle-layer peroxidation system is favorably released at a proper time, invalid decomposition is reduced, strong acid or violent pH fluctuation is prevented from permeating into an inner layer, the enzyme inactivation risk is reduced, the foaming process is mild, and the foaming effect is good. And the integral integrity of the tablet can be maintained.

The invention provides a preparation method of a gluconic acid-delta-lactone crystal, which comprises the following steps: (1) adding a gluconic acid-delta-lactone seed crystal into a gluconic acid supersaturated solution to stimulate graining, and growing the crystal at 65-75 DEG C for 10-16 hours to obtain seed crystal slurry; and (2) adding a gluconic acid saturated solution into the seed crystal mush prepared in the step (1), cooling and crystallizing to obtain the gluconic acid-delta-lactone crystal. According to the method, preparation of high-quality crystal slurry and crystal seeds in a single tank body and production of large-particle lactone crystals are achieved, the problems that in the lactone production process, viscosity affects nucleation, explosion is caused, and the growth rate is not matched with pushing force are solved, and compared with a sugar retention method adopted by an enterprise in the past, the single-tank yield is increased; the obtained crystals are large in particle size, narrow in distribution and uniform in particle size, more than 60% of the crystals are more than 40 meshes, the anti-caking capability is remarkably improved, the required seed crystals are few, and industrial production can be realized.

To provide a preventive or improving agent for neurological disorders caused by nerve damage resulting in reduced nerve function.SOLUTION: The preventive or improving agent contains a combination of quinoa or extract thereof and gluconodeltalactone.SELECTED DRAWING: None

The application discloses a preparation method and application of a sodium alginate-cyperus esculeus protein / isolated whey protein double-network gel, and comprises the following steps: step 1, mixing cyperus esculeus protein, isolated whey protein and sodium alginate to prepare a compound; and step 2, adding gluconic acid-delta-lactone and calcium carbonate into the compound to promote gel formation, so as to obtain a sodium alginate-cyperus esculeus protein / isolated whey protein compound gel induced by calcium acetate coordination. Compared with a pure protein gel, the sodium alginate-cyperus esculeus protein / isolated whey protein compound gel has excellent performances in texture characteristics, rheological characteristics and the like, and the water retention of the compound gel is also better than that of the pure protein gel. Moreover, the double network has a good encapsulation rate for curcumin and has a good slow-release effect.

This invention belongs to the field of veterinary drugs and discloses a method for preparing difloxacin suspension injection, comprising the following steps: Step 1: Difloxacin is added to an aqueous solution containing gluconolactone to prepare a difloxacin solution; Step 2: A crystallization inhibitor is added to the difloxacin solution in Step 1; Step 3: The solution is dispensed into glass vials for injection, sealed, and sterilized with high-temperature steam; Step 4: The sterilized injection solution is immediately subjected to cold water immersion or cooled to room temperature in air for leak testing and crystallization, simultaneously obtaining difloxacin injection solution. Based on previous research results, this invention further proposes that, in the further optimization process, gluconolactone is used as a co-solvent for difloxacin, dissolved by heating, dispensed into injection bottles, sterilized at high temperature, and then recrystallized after cooling to obtain a suspension with small crystal particle size. This process is suitable for large-scale production.

The problem to be solved is to provide a hair dye and a hair bleach that have a high hair repair effect. The solution of the problem is a hair dye or bleach containing glucono-δ-lactone, ammonia, and an ammonium salt of an acid.

The invention discloses chenopodium quinoa protein and sodium alginate compound emulsion gel as well as a preparation method and application thereof. The preparation method comprises the following steps: mixing and stirring a quinoa protein dispersion liquid and a sodium alginate dispersion liquid to form a physical mixture, then adding an oil phase (vegetable oil or vegetable oil-essential oil mixed oil), and carrying out shearing treatment to prepare a physical mixture emulsion; or mixing the quinoa protein dispersion liquid and the sodium alginate dispersion liquid, heating and stirring to form a covalent compound, adding the oil phase, and shearing to prepare a covalent compound emulsion; then calcium carbonate and glucolactone are added, and compact double-crosslinking emulsion gel is constructed. The hardness of the obtained gel is improved gt; the water binding capacity and the freeze-thaw stability are obviously enhanced, and the embedding rate gt of the plant essential oil is realized; and the fragrance release rate is reduced by 30%. The device is safe, efficient and adjustable in structure, and a novel edible carrier is provided for functional food and leisure food.

This invention discloses a continuous dynamic gradient cooling crystallization device for gluconolactone, comprising a cooling tank. Sealing plates are fixedly fitted onto the inner rings of both ends of the cooling tank. Several insulating plates fixed to the inner wall of the cooling tank are arranged between the two sealing plates, forming several chambers. An inner liner fixedly connected to the insulating plates is installed inside each chamber. A refrigeration pipe is installed between the cooling tank and the inner liner. A stirring mechanism is installed on the top sealing plate, and a filtration mechanism is installed on the insulating plates. This invention divides the cooling tank into multiple independent chambers through the insulating plates. Combined with the refrigeration pipe between the cooling tank and the inner liner, independent temperature control can be achieved for each chamber, forming a continuous gradient cooling environment. This design solves the problem of uncontrollable cooling gradient in traditional single-chamber cooling systems, allowing the gluconolactone solution to gradually and stably cool in each chamber, resulting in uniform supersaturation distribution and the formation of crystals with consistent particle size and regular morphology.

The invention discloses a method for improving the quality of marinated bean curd through a WOW emulsion type controlled-release coagulator, and aims to overcome the defects of rough bean curd gel network and poor water binding capacity caused by too fast release of marinating liquid in the prior art. The method comprises the following steps: respectively preparing a composite inner water phase containing bittern tablets and gluconic acid-lactone, an oil phase containing a hydrophobic emulsifier and a structured outer water phase containing water-soluble polysaccharide; shearing and mixing the inner water phase and the oil phase to prepare a primary W / O emulsion, and homogenizing the primary W / O emulsion and the outer water phase to prepare the W / O / W multiple controlled-release coagulator; and finally, adding into hot soybean milk, standing, incubating, squeezing and forming. According to the preparation method disclosed by the invention, physical isolation of the multiphase emulsion and chemical phase change synergy of the double coagulators are utilized, so that the release rate of magnesium ions is effectively delayed, polysaccharide macromolecules directly participate in gel skeleton construction, a compact and uniform three-dimensional interpenetrating network is formed, the water binding capacity of the bean curd is remarkably improved, the dehydration rate is reduced, and the product is endowed with an excellent texture.

The application relates to the field of food biotechnology, and discloses a low-salt bean paste production process based on segmented temperature control fermentation, which is made of fava bean koji, water, edible salt, sodium hexametaphosphate, lactococcus lactis nisin, edible alcohol, granulated coarse granular calcium carbonate and glucono-delta-lactone. The production process comprises the following steps: constructing a composite matrix, and first performing buffer-type medium-temperature enzymolysis; then adding a glucono-delta-lactone aqueous solution in a flow manner, utilizing the stoichiometric coupling reaction of the glucono-delta-lactone aqueous solution and the granulated coarse granular calcium carbonate to generate carbon dioxide in situ to construct a micropore structure and regulate the pH value of the system; and finally, connecting a Zygosaccharomyces rouxii to perform low-temperature aroma-producing after-ripening. Through the synergistic effect of the components, the application effectively solves technical problems in the low-salt fermentation process, such as low protein solubility, easy compaction of the matrix and breeding of miscellaneous bacteria, and improves the amino acid nitrogen content and protein hydrolysis rate of the finished product.

The present application relates to product processing technical field, disclose a kind of green preparation method of vacuum freeze-drying low-salt dry sea cucumber, the method includes: after the heat preservation pretreatment of salted sea cucumber, it is placed in the desalination protection soaking solution containing D-seaweed sugar, anhydrous betaine and D-sodium isoascorbate Circulating desalination until salt change stable;L-proline is added first, then low oligosaccharide powder, anhydrous calcium lactate and D-glucose acid-delta-lactone are added in turn, so that pH gradually decreases and is conditioned and shaped;After that, it is placed in vacuum freeze dryer, the crystallization exothermic recovery peak of sea cucumber center temperature is monitored, pre-freezing and deep freezing treatment are completed;Finally, internal moisture is sublimated by vacuumizing and heating, and low-salt dry sea cucumber is obtained from warehouse.The present application is beneficial to reduce protein loss and water consumption during desalination period, reduce COD value of discharged waste liquid, reduce volume shrinkage of finished product, and improve rehydration and texture performance.

The invention discloses a preparation process of empagliflozin, which comprises the following steps: by taking D-(+)-gluconic acid delta-lactone as a raw material, carrying out condensation reaction on D-(+)-gluconic acid delta-lactone and (R)-3-(4-(5-bromo-2-chlorobenzyl) phenoxy) tetrahydrofuran through a protective reagent under the action of a Grignard reagent; carrying out protonation reaction under the action of sulfuric acid to obtain an intermediate; and removing a protecting group through organic acid to obtain empagliflozin. The reaction route has the advantages of few steps, high selectivity, few byproducts, high product yield, easiness in product separation, convenience in operation, suitability for large-scale industrial production and the like, and is suitable for large-scale popularization and application.

The invention provides adhesive type gastric retention administration hydrogel as well as a preparation method and application thereof, and belongs to the technical field of bioactive materials and drug delivery methods. The drug delivery hydrogel is prepared by taking levodopa modified hyaluronic acid as a skeleton structure, gluconic acid-delta-lactone as an acidity regulator and potassium sorbate as a preservative. The preparation method comprises the following steps: grafting levodopa onto hyaluronic acid, dialyzing, and freeze-drying to obtain levodopa modified hyaluronic acid; gluconic acid-delta-lactone, potassium sorbate and levodopa modified hyaluronic acid are mixed and dissolved in water, and after a reaction, the drug delivery hydrogel is obtained. Anthocyanin is loaded in administration hydrogel to prepare the gastric retention sustained-release medicinal preparation. The prepared drug delivery hydrogel has good oxidation resistance, biocompatibility, adhesion and drug sustained-release capacity, the hydrogel is endowed with sustained-release drug delivery capacity through the wet adhesion effect in the stomach wall environment, and the drug delivery hydrogel is widely applied to the fields of bioactive materials, drug delivery and food.

A biphasic product comprising lactobionic acid, lactic acid or corresponding salts thereof and / or gluconolactone.

This invention relates to the field of green materials engineering technology, and discloses a low-VOC environmentally friendly pressure-sensitive adhesive for vehicle body stickers and its preparation method. The adhesive comprises deionized water, enzymatically hydrolyzed sodium lignin sulfonate powder, hydrogenated rosin glycerol ester, oxidized starch aqueous solution, ammonia, glucono-δ-lactone powder, and zirconium carbonate ammonium solution. During preparation, a microemulsion is formed by dispersing hydrogenated rosin glycerol ester using the amphiphilic properties of lignin under a shear field. After mixing with oxidized starch, latent acid, ammonia, and a crosslinking agent are added under laminar flow conditions. This invention utilizes the physicochemical coupling mechanism of ammonia volatilization and the thermal release of acid from glucono-δ-lactone to achieve synchronous homogeneous crosslinking at a thick coating depth, solving the problem of cohesive gradient defects. Simultaneously, it utilizes high-valence zirconium ions to construct a dynamic reversible coordination dissipation network, effectively dissipating peel tensile stress, avoiding cohesive-destructive residues, and eliminating the risk of VOCs and interfacial pinholes caused by small-molecule emulsifier residues, significantly improving heat resistance and tack performance.

The present invention concerns a pharmaceutical composition comprising glucono-δ-lactone, which is suitable for use in the treatment of vaginal microbial infections.

The invention provides double-layer modular thermal response hydrogel as well as a preparation method and application thereof, and belongs to the technical field of hydrogel preparation. The hydrogel is formed by stacking a temperature protection layer and a treatment layer in situ. The phase change temperature of the temperature protection layer can be accurately regulated and controlled, the treatment layer is prepared by mixing a sodium alginate solution, an MXene nanosheet dispersion liquid, a ciprofloxacin solution, delta-glucolactone and calcium carbonate and then cross-linking through calcium chloride, aggregation of MXene and ciprofloxacin due to electrostatic interaction is avoided by utilizing an ordered feeding sequence, and the treatment effect is improved. And uniform dispersion and stability of the components are ensured. The double-layer hydrogel integrates the photothermal effect and the membrane damage capacity of MXene and the chemical sterilization effect of ciprofloxacin, and synergistic and efficient antibiosis is achieved; the temperature protection layer on the upper layer can be repeatedly used, the treatment layer on the lower layer can be modularly replaced, and real-time monitoring and feedback of wound temperature can be achieved through electrical conductivity of MXene.

The application discloses a kind of geosynthetic materials of enhanced waterproof and drainage integrated structure, it is related to building material technical field.The geosynthetic material of the application includes geotextile and filled modified bentonite composition;Modified bentonite composition includes the following weight parts of raw materials: 85-95 weight parts modified bentonite, 2-7.5 weight parts modified cellulose.The preparation method of modified bentonite includes the following steps: S1: with active white clay, CaO is used as raw material dry, component two is washed with hydrochloric acid;S2: component two is obtained component three under the modification of gluconic acid lactone lactone;S4: component three, surface is polymerized to obtain modified bentonite by acrylamide.The geosynthetic material prepared in the application has the advantage of keeping low permeability under repeated load.

This invention discloses a compound leavening agent and its application, relating to the field of food processing technology. The compound leavening agent is composed of glucono delta-lactone and sodium bicarbonate in a mass ratio of 1:0.35~0.5. The compound leavening agent provided by this invention has a high degree of synchronization between its peak gas production and the steaming heating process, allowing the dough to be directly shaped, steamed, and cooked after kneading, significantly improving processing efficiency. The formula contains only two components, is free of aluminum, phosphorus, and fillers, making it safe, harmless, low-cost, and simple to process. The resulting pasta products have a smooth surface, fine pores, a pure wheat aroma, and no off-odors. The finished product has stable and uniform quality, is easy to operate, and is suitable for rapid and standardized production in chain restaurants, central kitchens, and home settings.

The application discloses lignin-hydroxyapatite / biomass-based composite aerogel and preparation and application thereof. In the application, hydroxyapatite is dispersed in a weak alkali solution, then sodium lignosulfonate and sodium alginate are added, and after uniform stirring, a gluconolactone solution is added dropwise, a hydrogel is formed after being poured into a mold, and the hydrogel is frozen by liquid nitrogen or a refrigerator, and then the composite aerogel is obtained by freeze-drying. In the application, sodium alginate is used as a base material, and lignin is introduced as a carbonization agent and a structure reinforcing agent, and the organic / inorganic composite aerogel is prepared by using the combination of the slow release of hydroxyapatite and the use of gluconolactone, so that the heat preservation performance, mechanical performance and smoke suppression performance of the composite aerogel can be significantly improved. The prepared aerogel is subjected to hydrophobic modification, so that the application field of the aerogel is greatly widened. The prepared aerogel has the characteristics of low thermal conductivity, high porosity, high strength and high flame retardancy, and simultaneously opens up a new way for resource utilization of lignin.

The invention relates to the field of seasonings, in particular to a solid-state compound seasoning with antibacterial and fresh-keeping functions and a preparation method of the solid-state compound seasoning. Each part of the solid compound seasoning comprises the following components in parts by weight: 20-40 parts of a core bacteriostatic unit, 50-70 parts of a flavor basic unit and 10-25 parts of a flavor enhancing and auxiliary bacteriostatic unit, wherein each part of the core antibacterial unit is prepared from 15 to 35 parts of antibacterial peptide concentrated powder and 5 to 15 parts of gluconic acid-delta-lactone; each part of the flavor basic unit comprises 20-40 parts of maltodextrin, 15-30 parts of edible salt and 5-15 parts of white granulated sugar; each part of the auxiliary antibacterial unit comprises 5-15 parts of vinegar powder, 3-8 parts of a composite natural spice extract and 2-5 parts of a yeast extract. The method can significantly reduce or even replace the use of chemical preservatives, conforms to the industrial trend of label cleaning, can be directly applied to various food processing links such as pickling, marinating and mixing, provides a revolutionary technical means for the preservation of instant foods such as meat products, aquatic products and vegetarian foods, and has extremely wide market prospects.

A transparent liquid composition is provided which has excellent handling properties when used in cosmetic production without causing increases in viscosity or precipitation of insoluble matter during storage, and which imparts hydrophobicity to damaged hair when added to a cosmetic, and is smooth, moist and soft so feels good during use; a cosmetic containing this transparent liquid composition is also provided. This transparent liquid composition is characterized by containing (A) a compound selected from a group consisting of peptides, amino acids and derivatives thereof, (B) fatty acid amidoamines, (C) gluconic acid and / or gluconolactones and (D) a polyhydric alcohol, wherein the mass ratio (C) / (B) of component (C) to component (B) is 0.5-2.0.

The invention discloses composite gel based on hydrogen bond reconstruction and directional crosslinking as well as a preparation method and application of the composite gel, and relates to the technical field of gel preparation. The preparation method comprises the following steps: mixing a sodium alginate solution with a cyclodextrin solution to obtain a mixed solution; the mixed solution is added into a first container, the first container is placed in a second container, and the bottom of the first container is provided with a cation exchange membrane communicated with the second container; a D-(+)-gluconic acid-delta-lactone solution and a nano calcium carbonate solution are added into the second container until the D-(+)-gluconic acid-delta-lactone solution and the nano calcium carbonate solution submerge the cation exchange membrane, calcium ions generated by the reaction of the D-(+)-gluconic acid-delta-lactone solution and the nano calcium carbonate solution enter the first container through the cation exchange membrane to react with the mixed solution, and the composite gel is obtained. Compared with common gel prepared by mixing, the bottom section of the composite gel prepared based on hydrogen bond reconstruction and directional crosslinking presents a more uniform and compact adsorption pore structure, and efficient adsorption of EGCG molecules is facilitated.