84 results about "Snake bites" patented technology

Protective chaps to provide protection against chainsaw cuts and, optionally, poisonous snake bites has a woven cloth-like shell lined by a layer of polyester / aramid fiber and, optionally, a partial layer of a woven material, all enclosed by an inside thin polyester fabric. The combination of zippers and hook-and-loop fasteners provides a dual fastener system that protects against freeze up and clogging of exposed zippers and may include alternate connections to provide two different tubular leg sizes.

The present invention is chicken yoke antibody (IgY) resisting Bengalese cobra venom and its preparation process. The preparation process includes water dilution to extract coarse IgY from chicken yoke, salting out IgY with ammonium sulfate, dissolving the precipitate in PBS, ultrafiltering to desalt, concentrating, anion exchanging chromatographic separation for further purifying IgY, ultrafiltering to desalt, concentrating, and freeze drying. The IgY exhibits single tape of molecular weight 200 KD in non-reductant SDS-PAGE and two tapes of molecular weight 65 KD and 35 KD separately in reductant SDS-PAGE, and has at least 13 dyeing strips of molecular weight 100-0.7 KD on PVDF film for Western Blot detection. The chicken yoke antibody (IgY) resisting Bengalese cobra venom may be used in preparing medicine and health food for preventing and / or treating snake bite, and in preparing reagent for detecting relevant snake venom.

This invention pertains to enclosed footwear in combination with a leg covering or body covering that is storable within a compartment that is integral with an exterior of the enclosed footwear. The leg covering can be either a gaiter or a pants leg portion, and the body covering can be either a sack portion or a suit portion. The leg covering or body covering can be of a material that is protective against biological attacks, chemical attacks, nuclear radiation and snake bites. The leg covering or body covering can also be flame resistant, thermally protective and cut proof.

The invention discloses a method for detecting and identifying the variety of snake venom by utilizing an adaptor technology, belonging to the field of biomedicine verification and relating to a method for detecting snake venom by utilizing the adaptor technology. Specific to the problems complex compositions of snake venom and poor specificity and sensitivity of the traditional snake bite detection method, the invention adopts a depletion SELEX (Systematic Evolution of Ligands by Exponential Enrichment) technology, and an adaptor with high-degree snake venom species specificity is obtained through screening and is converted into a report adaptor so as to establish a novel method for quickly detecting snake venom.

The invention relates to the technical field of biological medicine and provides an anti-sea snake neurotoxin SN160 nano antibody, a preparation method and an application. The anti-sea snake neurotoxin SN160 nano antibody is a VHH antibody and has an amino acid sequence shown as SEQ ID NO. (sequence identifier number) 1; a nucleotide sequence encoding the nano antibody is shown as SEQ ID NO. 2; affinity analysis shows the nano antibody has good affinity; small animal experiments prove that none of mice in an antibody protection group injected with the nano antibody in advance appears a neurotoxic symptom after injection of sea snake neurotoxin SN160; after continuous observation for a month, no death caused by the toxin happens; and therefore, the nano antibody has an excellent anti-sea snake toxin effect, an excellent prevention or treatment effect on sea snake bites and wide clinical application prospects.

A device for treating a snake bite wound that utilizes a hypodermic tube with a curvature that is similar to a typical snake fang whereby the hypodermic tube on one end comprises a smooth bulbous tip with at least one opening and a vacuum source is attached to the other end of the hypodermic tube. The tip is inserted into a snake bite wound, and due to the curved shape of the hypodermic tube, the tip and the tube then follow the curved shape of the snake bite wound without damaging any of the tissue surrounding the snake bite canal. The vacuum source then extracts any venom that is present from the wound. The device also enables medicine to be injected into the wounded area to treat the wound.

An alcohol extract of polygonum lapathifolium includes such steps as breaking, reflux extracting in alcohol 2-3 times, collecting filtrate, vacuum concentrating, centrifugal separation to obtain supernatant, extracting in ethyl acetate 2-3 times, collecting liquid extract, vacuum concentrating, silicagel column chromatography and eluting with TLC developer. It can be used for preventing and treating cancer, and treating bacillary dysentery, enteritis, eczema, snake bite, etc.

This invention relates to a preparation method of multivalent anti-snake venom chicken yolk antibody. It includes following steps:(1) collect different kinds of snake venom antigen; (2) preparation of chicken ovum of anti-snake venom chicken yolk antibody, and infuse snake venom to chicken for immunization, after 20 to 4 weeks continuously collect egg for 6 to 10 mouths.(3) extract multivalent anti-snake venom chicken yolk antibody. This product can replace horse serum for injection, and be able to developed as oral using drug which has extensive application prospects in prevention of snake bite.

Disclosed is a medicament for treating snake bites, which is prepared from atractylodes rhizome, dahurian angelica root, centipede 2 pieces, silver flower, capsule of weeping forsythia, ledebouriella root, scrophularia root and pollen.

The invention relates to a blood-activating and pain-relieving plaster, and a preparation method thereof. A formulation of the plaster comprises: garter snake, snake slough, nux vomica, doubleteeth angelica root, rheum, gansui root, scorpion, rehmannia dride rhizome, asurum uropeum, zhishi, fructus crotonis, almond, divaricate saposhnikovia, kusnezoff monkshood root, angelica archang lica, nutgrass galingale rhizome, clam powder, frankincense, pollen, whole ginseng, whole angelica, myrrh, knoxia root, herba ephedrae, dragon's blood, large cenpitede and forest musk. The preparation method comprises the following steps: pouring sesame oil or perilla oil to a container, boiling the oil, then adding garter snake, snake slough, nux vomica, doubleteeth angelica root, rheum, gansui root, scorpion, then adding other herbs, adding the dragon's blood after 4-5 hours; carrying out decocting with mild fire after all the herbs are added to the container; placing the decocted medical solution in cold water filled in a container to carry out cooling until the solution is transformed into the black solid. According to the present invention, the plaster can be directly pasted on the affected part of the human body and is applicable for most people; the plaster has characteristics of no skin irritation, no toxic and side-effect, simple process, fast release rate, quick therapeutic effect; the plaster is applicable for treating snake bite, small area burn, scald and other surgical wounds, and has effects of blood activating and pain relieving.

The invention relates to a rhizoma paridis alcohol. A formulation of the rhizoma paridis alcohol comprises: every 100 kilograms of pure grain alcohol with 50 degrees is mixed with 6 kilograms of rhizoma paridis, 3 kilograms of rhizoma smilacis glabrae and 2 kilograms of rock candy. The rhizoma paridis alcohol has the advantages of clearing away heat and toxic material, removing swelling, relieving pain, cooling liver, arresting convulsion, treating carbuncle swelling, treating snake bite and traumatic injury, activating blood, removing blood stasis, relieving blood, calming, inhibiting bacterial of trauma, diminishing inflammation, resisting virus, in particular having remarkable treatment effect on gastroenteritis, gastric ulcer and gastrorrhagia.

A phospholipase A2 inhibitor protein designated “Phospholipase Inhibitor from Python” (PIP)—formerly designated “Python Antitoxic Factor” (PAF)—is given by SEQ ID NO:2. The partial amino acid sequence for PIP was initially determined from the native protein purified from the blood serum of a non-venomous snake, Python reticulatus. The complete PIP polynucleotide sequence was obtained from a cDNA clone encoding PIP, given by SEQ ID NO:1, along with the full amino acid sequence deduced from it. Also disclosed is a recombinant protein PIP, which shows strong lethal toxin neutralizing activity similar to the native PIP, and has potent anti-inflammatory activity. Both the native and the functionally equivalent recombinant PIP are useful for the prevention or treatment of conditions such as snakebites, insect stings, and inflammatory diseases. Also, phospholipase A2 (PLA2) inhibitory polypeptides designated P-0029, P-0009, and P-0006, the sequences of which are given as SEQ ID NO:10, SEQ ID NO:11, and SEQ ID NO:12, respectively, are disclosed. Those polypeptides, and their synthetic chemical analogues and polypeptide variants that inhibit PLA2 activity and alleviate inflammation, may also be used in the diagnosis, study, prevention, and treatment of PLA2-related human inflammatory diseases.

A preparation method of a traditional Chinese medicine for treating snakebite. A formula comprises the following components by weight: 20-30 parts of herba andrographitis, 5-10 parts of paris polyphylla, 15-20 parts of wild chrysanthemum, 5-10 parts of pseudo-ginseng and 15-20 parts of plantain. A powder containing the components is prepared into a powder, flake or capsule. The traditional Chinese medicine can effectively act on components in toxins of a poisonous snake, such as neurotoxin, cytotoxin and hemotoxin to quickly suppress and neutralize the toxins of the poisonous snake and relieve pains and swelling. The medicine can effectively inhibit and neutralize snake venom, adapt to a variety of snake bites, and has remarkable effects.

The invention relates to medicinal liquor capable of killing bacteria, dispelling wind, removing obstruction in meridians and relieving pain and a preparation method thereof. The medicinal liquor is composed of, by weight, grasshoppers, sanchi, scorpions, centipedes, squama manis, chuanxiong rhizomas, tuberculate speranskia herbs, herba lycopodii, ground beetles, willow branches, rhizoma phragmitis, starfishes, Chinese prickly ash, Sichuan pepper, mature ginger, turtle shells, bulbus allii, rhizoma gastrodiae and bark of Japanese cinnamon. The medicinal materials are immersed in baijiu, so that the medicinal liquor is obtained. The medicinal liquor has the effects of dispelling wind, eliminating dampness, dispelling cold, relaxing tendons, dredging collaterals, promoting blood circulation to remove blood stasis, promoting qi circulation to relieve pain, removing toxic materials, eliminating stagnation, eliminating swelling, expelling pus, diminishing inflammation and killing bacteria, can promote blood circulation, restore joint and cartilage injury, eliminate infection cells and restore healthy skin and is effective for various bone joint diseases, various skin diseases, snake bites, haemorrhoids and gynecologic inflammation, the total effective rate reaches 97.02%, and the cure rate reaches 60.71%.

The disclosure describes emergency or first aid snake bite treatment devices that include a belt or other securing member attached to a compression (bite isolation) member, the compression member having an outwardly projecting wall that is configured to surround the snake bite and compress the skin about the snake bite a distance inward to thereby isolate the venom from the bite to impede the venom from entering a victim's lymphatic system.

The invention discloses an externally-used analgesic medicinal composition. The externally-used analgesic medicinal composition comprises the following components: toad venom, scorpio, ligusticum wallichii, trogopterus dung, resina liquidamberis, radix curcumae and turmeric. Through combination of the toad venom and the scorpio with strong analgesic effects, the externally-used analgesic medicinal composition can be used for treating patients suffering from severe pains; in coordination with the Chinese herbs, namely the trogopterus dung, the resina liquidamberis, the radix curcumae and the turmeric, which are used for treating traumatic injuries, snake bites, insect bites, stabbing chest pains, and precordial pains with chest discomfort, the externally-used analgesic medicinal composition can be used for treating different pains; with the assistance of the ligusticum wallichii, the externally-used analgesic medicinal composition can activate blood circulation, remove stasis and dredge veins. Therefore, the externally-used analgesic medicinal composition provided by the invention has a significant therapeutic effect on the paints.

The invention discloses a traditional Chinese medicine for treating poisonous snake bites. Each dose of the medicine is prepared from the following medicinal materials by mass: 6g to 9g of centipede, 6g to 9g of gold scorpion, 12g to 18g of plantain herb, 12g to 18g of radix angelicae, 12g to 18g of spica prunellae, 12g to 18g of wild chrysanthemum flower, 12g to 18g of dandelion, 20g to 30g of circium japonicum, 20g to 30g of lalang grass rhizome and 45g to 55g of Chinese lobelia. The traditional Chinese medicine has a good effect of treating the poisonous snake bites, has a curative rate of 100%, can take effect rapidly and is easy to prepare, low in cost and especially applicable to most of rural areas.

The invention relates to the technical field of biomedicine, and provides a nanometer antibody against sea snake neurotoxin, a preparation method and applications thereof, wherein the nanometer antibody against sea snake neurotoxin is a VHH antibody, and has an amino acid sequence represented by SEQ ID NO.1, and the nucleotide sequence encoding the nanometer body is represented by SEQ ID NO.2. According to the present invention, the affinity analysis results show that the nanometer antibody has good affinity; the small animal experiment results prove that the mice in the antibody-protected group pre-injected with the nanometer antibody of the present invention do not produce neurotoxic symptoms after injection with sea snake neurotoxin SN36, and no toxin induced death condition is generated after continuous observation for one month, such that the results indicate that the nanometer antibody has excellent anti-sea-snake-toxin effect, has excellent prevention or treatment effects on seasnake biting, and has broad clinical application prospects.

The invention relates to a Rhizoma Paridis medicinal powder and the preparation method thereof. The powder comprises Rhizoma Paridis 80 to 90wt%, Herba Cirsii Japonici 7 to 12wt% and Herba Cephalanoploris 2 to 6wt%. The preparation method comprises selecting qualified materials of Rhizoma Paridis, Herba Cirsii Japonici and Herba Cephalanoploris, soaking in clean water for 2 to 4 h, taking out, slicing, oven-drying, and pulverizing to powder by a pulverizer. The powder has significant curative effects on various heat-toxin and pain diseases caused by innominate toxic swelling, swelling, furuncle, snake bite, throat pain and various pain diseases, and has effects on clearing away heat and toxic materials and alleviating swelling and pain. The medicinal powder can be encapsulated for treating diseases and stopping pain, and has the advantages of convenient carriage, simple administration and safe and reliable usage.

A preparation method for snakebite emergency medicine is disclosed, and the medicine comprises: 5-12 parts of Chinese trumpetcreeper flower root, 5-12 parts of ainsliaeafragrans champ, 3-5 parts of angelica dahurica, 5-10 parts of andrographispaniculata, 1-4 parts of polyphylla, 5-10 parts of cirsiumjaponicum root, and 7-12 parts of Chinese lobelia. The method is carried out by the following steps: 1) taking and crushing Chinese trumpetcreeper flower root, polyphylla and angelica dahurica, mixing uniformly to obtain a fine powder of Chinese trumpetcreeper flower root, polyphylla and angelica dahurica; 2) taking cirsiumjaponicum root, ainsliaeafragrans champ, andrographispaniculataandChinese lobelia, adding water and decocting, concentrating the filtrate to a clear paste state; 3) adding the fine powder of Chinese trumpetcreeper flower root, polyphylla and angelica dahurica into the clear-paste-state filtrate, mixing uniformly; and 4) drying, crushing to obtain a fine powder. Through years of clinical use, the above medicine belongs to a snakebite emergency and therapeutic medicine with substantial curative effect, no untoward effect, convenient taking and storage, and low price. The snakebite emergency medicine is used to cure various poisonous snake bites, and has effects of clearing heat, detoxifying, stopping bleeding, diminishing swelling and relieving pain.

The invention relates to an emergency antidote for relieving snake venom. The antidote is prepared from the following raw materials by weight: 10-16 parts of radix sileris, 8-12 parts of radix angelicae, 8-16 parts of excrementum pteropi, 12-20 parts of Andrographis paniculata, 20-40 parts of Sculellaria barbata and 14-22 parts of ginger. The prepared product has antibacterial, antiviral, antipyretic and anti-inflammatory effects, and has good curative effects on local swelling, pain, tissue necrosis and bleeding caused by snake bite.

The invention discloses a portable field snake bite emergency detoxifying device. A cylindrical suction cylinder is provided with a liquid suction taper hole, a one-way valve, a liquid drainage hole and a piston connected with a suction handle, the outer lower end of the suction cylinder is provided with a suction nozzle, and a liquid storage tank provided with a liquid discharge valve is disposedoutside the liquid drainage hole. The portable field snake bite emergency detoxifying device can be used for effectively rescuing a poisoned person bit by a snake in time, does not cause danger to arescuer, and is convenient to use and safe. The small device provides great guarantee when people meet with danger in the field during traveling.

The invention provides an oxygen-carrying bionic nano antidote, and a preparation method and application thereof. The oxygen-carrying bionic nano antidote with an oxygen-carrying function is obtained by wrapping an oxygen-carrying liquid perfluorocarbon compound with an erythrocyte membrane modified by phospholipid derivative oleic acid oxyethyl phosphorylcholine. The obtained bionic nano antidote is good in detoxification effect, toxin-induced hemolysis can be weakened, the hypoxia phenomenon caused by snake bites is relieved, degenerative necrosis of tissue cells is reduced, and wound healing is promoted.

The invention provides a snake bite wound sucking device for hand and foot surgery. The snake bite wound sucking device comprises a binding mechanism for binding a hand and foot proximal part and a sucking mechanism for discharging toxemia out of a human body. The binding mechanism is connected with the sucking mechanism. The sucking mechanism is arranged on one side of the binding mechanism. Thesucking mechanism comprises a suction mechanism for sucking toxemia and a driving mechanism for adjusting the suction mechanism and skin. The suction mechanism is arranged on one side of the binding mechanism. The driving mechanism is connected with the binding mechanism. By means of the snake bite wound sucking device for hand and foot surgery, when people get bitten by a snake outdoors, toxemiaat a wound is more easily discharged, and personal risks caused when the toxemia is sucked by a mouth in the past are avoided.

The invention discloses traditional Chinese medicine snake sore paste. The traditional Chinese medicine snake sore paste is prepared by the raw materials in parts by weight of 15-30 parts of realgar,15-20 parts of sweet potato leaf tips, 10-20 parts of faeces trogopterpri and 10-20 parts of black peppers. The medicine materials used by the traditional Chinese medicine snake sore paste have the efficacy of removing snake venom, the two medicines capable of relieving pain and diminishing inflammation, namely the faeces trogopterpri and the realgar are added, the black peppers are used for warming the middle warmer to resist cold toxin due to bite of snakeworms, and the efficacy of promoting circulation of blood, reducing the swelling and the like is achieved; Bidens pilosa L. and sixangulardysosmatis rhizomes have efficacy of clearing heat, removing toxicity, inducing diuresis for removing edema and the like; and 80% of patients bitten by the snakeworms can be recovered after medication is performed for five days, and 99.9% of the patients bitten by the snakeworms can be rehabilited after medication is performed for fifteen days

The invention relates to a combination and preparation method and a manufacturing technique of a snakebite tablet, and the steps are as follows: 50 percent of the formula amount of the raw materials of common andrographis herb, paris polyphylla smith and wild chrysanthemum are taken, the mixture is put in a stainless steel extraction kettle after cleaning, an appropriate amount of tap water is added, an appropriate amount of magnesium stearate is added after three times of extraction, and a finished product is formed by granulation and compression. The snakebite tablet can not only effective eliminate the snakebite for the people from all walks of life during regular field activities or travelling, but also can enhance immunity, promote metabolism and retard aging. The manufacturing technique of the invention is simple and the cost is low.

The invention belongs to the field of field first aid, and relates to snake venom suction first-aid equipment for field snake bite. The snake venom suction first-aid equipment for field snake bite comprises a shell and is characterized in that a disinfection cavity is formed in the upper side of the shell, a disinfection motor is fixedly arranged on the left side wall in the disinfection cavity, and a disinfection threaded shaft is arranged at the output end of the disinfection motor; and an internal thread sliding block groove is fixedly formed in the lower side wall of the disinfection cavity, and a lower extending block is arranged on the internal thread sliding block groove in a sliding mode. The snake venom suction first-aid equipment is suitable for being used after being bitten by snakes outdoors, after wounds are bundled, the wounds can be disinfected firstly, viruses and bacteria are prevented from entering from the wounds, then the wounds are provided with cross-shaped wounds, then snake venom is sucked out, the danger caused after the wounds are bitten by the snakes outdoors is effectively relieved, and enough medical treatment time is provided for injured people, so that the life safety is guaranteed.

The invention discloses a traditional Chinese medicine for treating snake wound. A dose of the traditional Chinese medicine is prepared from the following medicine materials by mass: 6-9 g of centipede, 6-9 g of gold scorpion, 12-18 g of plantain herb, 12-18 g of radix angelicae, 12-18 g of prunella spike, 12-18 g of wild chrysanthemum flower, 12-18 g of dandelion, 20-30 g of circium japonicum, 20-30 g of lalang grass rhizome and 45-55 g of Chinese lobelia. The traditional Chinese medicine has a good effect of treating poisonous snake bite; the curative ratio is 100%; the traditional Chinese medicine is quick in effect, easy to prepare, low in cost and especially suitable for large rural areas.