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494results about How to "Fast release" patented technology

Charcoal-based organic fertilizer and preparation method thereof

The invention relates to a charcoal-based organic fertilizer and a preparation method thereof. The charcoal-based organic fertilizer has the advantages of low cost, environment friendliness, good fertilizer efficiency, wide application range, high fertilizer efficiency utilization rate and pest prevention. The preparation method comprises the steps as follows: adding starter cultures to chicken manure and soybean meal respectively for fermentation, after drying, crushing and mixing crop-residue-derived carbon, the treated chicken manure and soybean meal with ground phosphate rock, adding wood vinegar to the mixture with stirring, performing granulation, and obtaining the charcoal-based organic fertilizer after cooling and drying.
Owner:五常市科发瑞扬农业有限公司

Oros push-stick for controlled delivery of active agents

A sustained release dosage form is provided comprising a pharmaceutically active agent and pharmaceutically acceptable salts thereof and adapted to release as an erodible solid over a prolonged period of time, wherein the dosage form provides burst release of the pharmaceutically active agent without the use of an immediate release drug coating. The dosage form is able to deliver high doses of poorly soluble or slowly dissolving active agents at a controlled rate. Methods of using the dosage forms to treat disease or conditions in human patients are also disclosed.
Owner:ALZA CORP

Article to be Inserted in a Body Cavity Having Biologically Inhibiting Surfaces and Use and Preparation of the Article

An article to be inserted in a human or animal body cavity, use of the article and preparation thereof. The article has a biologically inhibiting arrangement of electrically connected electrode materials in direct contact with each other on one or more surfaces of the article The arrangement includes as electrode materials a metallic anode material and a cathode material, where the potential of the cathode material is higher than the potential of the anode material, The cathode material is an electrically conductive material selected among certain non-metallic materials. The arrangement provided on the article releases biological inhibiting ions of the metallic anode material or complexes of such ions when the biologically inhibiting arrangement is contacted with a body fluid. The article can be designed with a controlled release rate suitable for the purpose in question for example an initial high rate of ion release after insertion of a catheter to combat bacteria introduced during the insertion followed by a prolonged release at a lower rate to maintain a low level of bacteria.
Owner:IMPACTCARE

Silicon carbide crystal annealing process

The invention is mainly applied to the field of treatment after silicon carbide crystal growth completion and particularly relates to a silicon carbide crystal annealing process which is specifically characterized by reducing the temperature gradient (the temperature gradient of the crystals is 1-10 DEG C / cm), spending 1-5 hours in raising the temperature to the annealing temperature under the inert gases with pressure of above 0.01-0.08MPa and then spending 10-50 hours in reducing the temperature after keeping the constant temperature for 10-40 hours, wherein the annealing temperature is 2300-2500 DEG C. By adopting the annealing process, the stress between the crystals and a crucible cover and the stress inside the silicon carbide crystals are reduced, thus reducing the damage rate of the silicon carbide crystals in the follow-up processing course and improving the yield of the silicon carbide crystals.
Owner:BEIJING TIANKE HEDA SEMICON CO LTD

User identifying module service and method and system for using personalized tailered issuing

This invention relates to a service for identifying modules by users, individuation customization method and a system, in which, a card-issuing person selects a character group individuation script file to be applied to analyze and execute the customization process, the issuing system sets the OTA state as registered and reads information needed by generating the OTA message, the issuing system reads the order data used in individuation customization in the script file to be arranged to OTA instruction with the message head then to turn it to APDU instruction to be sent to the card, the issuing system sends information synchronous ATA instruction to judge if the operation is successful, if so and the OTA registered initial state is un-registered, then it restors the counter of the user identified module by the APDU instruction to set the OTA un-registered, otherwise it updates the A / B value of the counter in the issuing system data base the latest value.
Owner:CHINA MOBILE GROUP JIANGSU +1

Manufacture of microspheres using a hydrocyclone

ActiveUS20120205293A1Faster rateLarge volume rapidlyAntibacterial agentsSievingActive agentEngineering
This disclosure features a system for processing microspheres. A vessel contains a suspension of solidified microspheres comprising polymer and an active agent. A hydrocyclone has a fluid inlet, a first fluid outlet and a second fluid outlet. The fluid inlet is in fluid communication with the vessel and receives the suspension. The second fluid outlet contains a flow of the suspension having concentrated microspheres. The first fluid outlet contains a flow of a relatively large amount of liquid compared to the flow from the second fluid outlet. Also featured is a method of processing the microspheres using the hydrocyclone.
Owner:OAKWOOD LAB LLC

Levamlodipine besylate tablet, preparation process thereof and control method for relevant materials

The invention relates to a levamlodipine besylate tablet, a preparation process thereof and a control method for relevant materials. Each 1000 levamlodipine besylate tablets provided by the invention comprise the following compositions: 2.5g of levamlodipine besylate (measured in besylate), 30 to 50g of lactose (as a filler), 20 to 40g of beta-cyclodextrin (as an inclusion agent), 25 to 45g of microcrystalline cellulose (as a disintegrating agent), 5 to 15g of cross-linked polyvinylpyrrolidone (as a disintegrating agent), 1 to 2g of magnesium stearate (as lubricant), and 50 to 80g of 2.5% HPMC (hydroxypropyl methylcellulose) and 50% ethanol (as an adhesive). The levamlodipine besylate tablet provided by the invention has the advantages of making multi-item improvements on the properties of the levamlodipine besylate, increasing the solubility and apparent dissolution rate of the tablet, improving the stability of the tablet, reducing the excitability of the tablet, significantly reducing the limit of the relevant material, and having better clinical treatment effect, so that the blood pressure lowering of the patient with hypertension is more stable.
Owner:JIANGXI SHIMEI PHARM CO LTD

Water-soluble micro powder containing florfenicol and preparation method thereof

The invention discloses a water-soluble micro powder containing florfenicol and a preparation method thereof. The micro powder is prepared from the following raw materials in percentage by weight: 5 to 10 percent of florfenicol, 2.5 to 2.75 percent of PVPK30, 2.5 to 2.75 percent of SDS and the balance anhydrous glucose. PVPK30, SDS and florfenicol are mixed uniformly, crushed, pass through a 150mesh screen, and then are added with the anhydrous glucose to be mixed uniformly. The micro powder also can be combined with other medicines to prepare water-soluble compound florfenicol micro powder. The grain size of the florfenicol through micro powder treatment is finer and more uniform, so the surface area is increased, the porosity is increased, the absorbability and the solubility are improved, the medicines can be well dispersed and dissolved in gastric juice, the contact area with gastric mucosa is enlarged, so that the medicines can be absorbed by the gastrointestinal tract more easily, thereby greatly improving the bioavailability. The preparation method is more convenient than a coating process, and is more applicable to large-scale production.
Owner:山东迅达康兽药有限公司

Cherry tomato matrix cultivation method

The invention discloses a cherry tomato matrix cultivation method comprising the following steps: 1, cultivation matrix preparation; 2, seed selection; 3, seed processing; 4, sowing and after sowing management; 5, colonization; 6, after colonization management; 7, setting up whole branches; 8, spike flowering and fruiting period; 9, fruit picking. The invention scientifically and reasonably designs the cherry tomato matrix cultivation method according to cherry tomato growth features; the prepared cultivation matrix is prepared specifically for cherry tomato growth, and made of straws rich in nitrogen, phosphor, potassium, calcium, magnesium and organic matters; the cultivation matrix fermented by natural raw materials can meet the crop growth needs, has better fertility than fertilizers purchased in the market, can be easily absorbed, and the fertility can be fast released. The matrix cultivation method can obvious improve cherry tomato quality and output.
Owner:LINYI UNIVERSITY

Chewable and deformable oral pouched snuff product

The present disclosure relates to an oral pouched snuff product and a method for its production. The oral pouched snuff product comprises a filling material and a saliva-permeable pouch enclosing the filling material, the saliva-permeable pouch comprising at least one elongated seal and the saliva-permeable pouch comprising a mesh material being elastic in at least one direction and comprising fibres of thermoplastic polyamide, wherein the at least one elongated seal has a seal strength of at least 0.10 N / mm as measured in dry state as well as in wet state. The at least one elongated seal may be an ultrasonically provided weld.
Owner:SWEDISH MATCH NORTH EURO

Internal memory management method and mobile terminal

The invention discloses an internal memory management method and a mobile terminal. The internal memory management method comprises the following steps: grouping non-system applications running in the background in a mobile terminal system to obtain more than one application group; and when the current use proportion of the internal memory in the mobile terminal exceeds a first preset threshold, or when the current use proportion of the internal memory of all application groups exceeds a second preset threshold, closing the non-system applications according to the application groups to release the internal memory. According to the internal memory management method disclosed by the invention, the non-system applications are grouped at first, and when the internal memory resources are insufficient, the non-system applications are closed based on the application groups, therefore the release speed of the internal memory resources is improved. In addition, the internal memory management is performed based on the application groups instead of based on a single non-system application, so that the internal memory occupied by the non-system applications can be managed more macroscopically, and thus the user experience is improved.
Owner:BEIJING ZHUMU LANGMA MOBILE COMM CO LTD

Metformin hydrochloride enteric-coated tablet

The invention discloses a metformin hydrochloride enteric-coated tablet, which comprises a tablet core and an enteric-coated layer. The tablet core is prepared by the following raw materials by weight: 100 parts of metformin hydrochloride, 3-5 parts of povidone K30, 8-12 parts of 75% ethanol water containing 10% povidone K30 and 0.5-1.0 part of magnesium stearate. The enteric-coated layer is prepared by the following raw materials by weight: 100 parts of eudragit L30D-55, 10-30 parts of talcum powder, 2-4 parts of polyethylene glycol 4000, 4-6 parts of 4% sodium hydroxide solution and 80-120 parts of purified water. The preparation process includes the steps of weighing all raw materials according to proportion, preparing the tablet core, preparing enteric-coated solution and then obtaining the metformin hydrochloride enteric-coated tablet. The metformin hydrochloride enteric-coated tablet simplifies preparation technology, effectively reducing manufacture cost, can simultaneously control releasing speed, and effectively guarantees clinical effects of products.
Owner:HEBEI JAMESHILL PHARMA

Biodegradable high-polymer bonded photoactive Pt (IV) anticancer medicament micelle and preparation method thereof

The invention provides a biodegradable high-polymer bonded photoactive Pt (IV) anticancer medicament micelle and a preparation method thereof, which relate to the field of novel chemical synthesis medicaments and preparations thereof and are used for solving the problem that a high-polymer-platinum (IV) bonded medicament does not have optical activity in the prior art. In an anticancer medicament, ethylene glycol-b-polyester-b-polylysine serving as a biodegradable triblock copolymer or polyethylene glycol-b-poly(ester-co-carbonic ester) serving as a diblock copolymer is taken as a carrier polymer, and Pt (IV) is a photoactive tetravalent platinum composition coordinated with dihydroxyl in the axial direction. The invention further provides a preparation method of the biodegradable high-polymer bonded photoactive Pt (IV) anticancer medicament micelle. The anticancer medicament prepared with the method has remarkable optical activity; under the irradiation of UV (Ultraviolet) of 365 nanometers, Pt (IV) is reduced into Pt (II); a cis-platinum or oxaliplatin antitumor active part is contained; and the mass content of platinum can be up to 10-20 percent.
Owner:吉林市博禹祥实工贸有限公司

Biological humic acid water soluble fertilizer

The invention discloses a biological humic acid water soluble fertilizer. The biological humic acid water soluble fertilizer is composed of, by weight, 7 to 10 parts of potassium nitrate, 8 to 12 parts of ammonium nitrate, 8 to 11 parts of monoammonium phosphate, 12 to 16 parts of urea, 18 to 23 parts of humic acid, 0.04 to 0.08 part of amino acid chelated trace element, 11 to 15 parts of a composite microbial agent, 20 to 25 parts of organic matter, 6 to 9 parts of sodium sulfafe decahydrate, 3 to 5 parts of boric acid, 5 to 8 parts of magnesium sulfate monohydrate, 0.5 to 0.9 part of a biogenic stimulant, and 2 to 4 parts of an anti-caking agent. The biological humic acid water soluble fertilizer is comprehensive in nutrient composition, and reasonable in formula; mutual cooperation of the elements in the biological humic acid water soluble fertilizer is achieved; fertilizer utilization rate is increased; and the biological humic acid water soluble fertilizer is capable of improvingcrop disease resistance and stress resistance, and increasing crop yield and product quality.
Owner:湖北吾尔利生物工程股份有限公司

Parking lot management method, server, camera and terminal device

The present invention discloses a parking lot management method, a server, a camera and a terminal device. The method comprises the steps of: obtaining license plate numbers and face information identified according to vehicle entering images collected at an entrance of a parking lot, and taking the license plate numbers, the face information and the vehicle entering time as vehicle entering datawhich is stored in a database; obtaining license plate numbers and face information identified according to vehicle exiting images collected at an exit of the parking lot, searching vehicle entering data matching with the license plate numbers and face information identified in the vehicle exit images from the database, performing calculation according to the searched vehicle entering time in thevehicle entering data and the current vehicle exiting time, obtaining parking fee information, and performing parking fee processing according to the parking fee information. The parking lot management method, the server, the camera and the terminal device achieve the purpose of verifying vehicle owner identity of a leaving vehicle so as to improve the vehicle safety and prevent the vehicle from being stolen.
Owner:北京悦畅科技有限公司

Method and device for measuring sulfur content in coal by ultraviolet absorption spectroscopy

The invention discloses a method and a device for measuring sulfur content in coal by ultraviolet absorption spectroscopy. In the measurement method, the decomposition scale and a threshold are determined adaptively by combining empirical mode decomposition with 3sigma criterion, and non-stationary characteristics of differential absorption degree per se can be fully retained, so the spectral interference problem caused by dust, water vapor and background gas in combustion gas is effectively solved; the instantaneous concentration of SO2 is obtained through calculation according to the differential absorption degree after noise reduction and trend term removal, and the total sulfur content accumulated in the coal sample combustion gas is calculated through the gas flow; the sulfur content in the coal can be obtained by dividing the coal sample amount by the total sulfur content separated from the coal sample combustion; and the pretreatment process needed to be performed on the combustion gas by coulometric titration and an infrared absorption method is avoided. The device for measuring the sulfur content in the coal by the ultraviolet absorption spectroscopy comprises a combustion furnace, a measuring chamber, an ultraviolet light source, a spectrometer, an air purifying device, a flow meter, a waste gas treatment device, a computer, and the like.
Owner:SOUTHEAST UNIV

Erbium-chromium-codoped zinc gallate stannate near infrared long-afterglow material and preparation method thereof

The invention discloses an erbium-chromium-codoped zinc gallate stannate near infrared long-afterglow material and a preparation method thereof. The structural formula of the material is Zn1+xGa2-2xSnxO4:nCr, mEr, wherein 0<x<0.4, 0.002<n<0.05, and 0.005<m<0.02. The near infrared long-afterglow material has the advantages that the material emits 650-800nm-waveband near infrared long afterglow, the emission peak is located at 695nm, and the material has higher afterglow intensity and longer afterglow time as compared with those of a chromium-doped near infrared long-afterglow material.
Owner:JILIN UNIV

Oros push-stick for controlled delivery of active agents

InactiveUS20100196425A1Faster initial rate of releaseFast releaseBiocidePill deliveryDiseaseSustained release drug
A sustained release dosage form is provided comprising a pharmaceutically active agent and pharmaceutically acceptable salts thereof and adapted to release as an erodible solid over a prolonged period of time, wherein the dosage form provides burst release of the pharmaceutically active agent without the use of an immediate release drug coating. The dosage form is able to deliver high doses of poorly soluble or slowly dissolving active agents at a controlled rate. Methods of using the dosage forms to treat disease or conditions in human patients are also disclosed.
Owner:ALZA CORP

Magnetic targeting carrier capable of carrying gene and drug, preparation method and application thereof

The invention discloses a magnetic targeting carrier capable of carrying genes and drugs, a preparation method and an application thereof. The invention is a carrier which has stability, safety and targeting and has controlled release behavior for non-viral magnetic gene therapy and drug therapy. The carrier material of the invention is characterized in that the carrier material is a bunchy silica mesoporous material with magnetism; the length-diameter ratio is not less than 3; the loading capability is big; the material has a protective effect on loaded genes and carriers and superparamagnetism, is not easy to agglomerate, and can control release speed of genes and drugs in vitro; and the surface thereof is easy to modify various functional groups, thus having wide adaptability. The invention also provides a preparation method of the carrier. When in use, therapeutic short chain DNA, siRNA or drugs enter in holes or are combined with surface modified functional genes by a soaking mode, then reach a targeted tissue by guidance of an applied magnetic field, and release the short chain DNA, siRNA or drugs carried thereby under the action of an alternating magnetic field, thus achieving the purpose of magnetic targeting controlled therapy.
Owner:CENT SOUTH UNIV

Antibacterial powder coating

The invention discloses an antibacterial powder coating, prepared from the following raw materials by weight: 25 to 35 percent of epoxy resin, 25 to 35 percent of polyester resin, 0.8 to 1.5 percent of flatting agent, 0.8 to 1.5 percent of smooth degasifier, 0.3 to 1.5 percent of antibacterial agent and 25.5 to 48.1 percent of pigment and filler. A coating film formed after the antibacterial powder coating material is sprayed and cured has excellent antibacterial performance, and takes effect quickly in antibacterial capability, and the effect is long-acting and lasting.
Owner:六安科瑞达新型材料有限公司

Fruit cucumber culture medium and preparation method thereof

The invention discloses a fruit cucumber culture medium and a preparation method thereof. The fruit cucumber culture medium comprises substances in parts by weight as follows: 50-70 parts of crop straw, 25-30 parts of peanut hulls, 23-36 parts of soybean meal, 10-18 parts of humic acid, 10-15 parts of algae, 13-20 parts of corncobs, 5-13 parts of distillers' grains, 19-27 parts of plant ash, 15-21 parts of bone meal, 30-46 parts of poultry manure, 16-27 parts of peat soil and 11-17 parts of mushroom residues. The prepared culture medium is a special culture medium for growth of fruit cucumbers. The straw used in the prepared culture medium is rich in nitrogen, phosphorus, potassium, calcium, magnesium, organic matters and the like, the culture medium produced by fermenting natural raw materials is close to media required by growth and development of crops, the culture medium has higher fertilizer efficiency and is easier to absorb than fertilizer purchased in the market, and besides, the fertilizer efficiency release speed is high. The fermentation effect during preparation of the culture medium is good, the content of microorganisms in obtained organic fertilizer is high, and 3-5 hundred millions of CFUs (colony-forming units) exist in each gram of the organic fertilizer.
Owner:LINYI UNIVERSITY

Preparation method for solid freshener

The invention belongs to the field of an air freshener and especially relates to a preparation method for a solid freshener. The method comprises the following steps: (1) preparing a stable chlorine dioxide solution; (2) preparing a colloid activating agent; (3) preparing microcapsule essence particles; (4) preparing the solid freshener. The solid freshener prepared according to the preparation method provided by the invention has an excellent air purifying effect; the essence powder is prepared from natural green plants and is green and safe; a microcapsule technique is cooperatively used for slowly releasing the fragrant active materials at a constant speed, so that the purpose of improving air quality can be achieved.
Owner:宁波宝和日化有限公司

Cherry tomato culture medium and preparation method thereof

The invention discloses a cherry tomato culture medium and its preparation method. The cherry tomato culture medium comprises the following substances (by weight): 65-80 parts of crop straw powder, 30-45 parts of soybean meal, 15-26 parts of peanut meal, 15-20 parts of spent mushroom compost powder, 14-20 parts of humic acid, 13-20 parts of algae powder, 20-26 parts of plant ash, 15-21 parts of fishbone dust, 13-18 parts of Styphnolobium japonicum wood dust, 9-16 parts of pine needle meal, 25-35 parts of poultry manure, 20-35 parts of peat soil and 10-16 parts of coal ash. The invention also provides a preparation method of the cherry tomato culture medium. The prepared culture medium is specifically a culture medium for growth of cherry tomato. Straw used for the prepared culture medium is rich in nitrogen, phosphor, potassium, calcium, magnesium and organic matters, etc. The culture medium produced by fermentation of natural raw materials meets crop growth and development requirements, has more excellent fertility than a fertilizer purchased in the market, is easier to absorb and has fast release speed of fertility. The prepared culture medium can be used to remarkably raise quality and yield of cherry tomato.
Owner:LINYI UNIVERSITY

Double-magnetic-response temperature-sensitive microcapsules and preparation method thereof

The invention discloses double-magnetic-response temperature-sensitive microcapsules and a preparation method thereof. A temperature-sensitive polymer is coated on the surface of magnetic nanoparticles and filled into the wall material of the microcapsules; under the action of an alternating magnetic field, the magnetic particles generates heat due to a magnetic lag effect the temperature of the magnetic particles thus rises, and when the temperature T is higher than the lowest critical solution temperature (LCST), the wall material forms lots of pores due to the shrinkage of the temperature-sensitive nanoparticles, the diffusion resistance to the medicine molecules passing through the wall material of the microcapluses is small and the release speed is high; and when the temperature T reaches the LCST, the temperature-sensitive magnetic nanoparticles expand to fully fill the pores in the wall material of the microcapsules, the diffusion resistance to the medicine molecules passing through the wall material of the microcapsules is big, and the release speed is low. Therefore, by regulating the synergetic effect between the temperature-sensitive structure of the temperature-sensitive polymer on the surfaces of the magnetic nanoparticles and the magnetothermal effect of the alternating magnetic field, the controlled release of the embedded medicine is realized. The microcapsulesprepared by the invention have double magnetic response and a temperature-sensitive controlled-release property.
Owner:PUTIAN UNIV

Cefuroxime axetil odor-masking pellet and preparation method

The invention relates to a cefuroxime axetil odor-masking pellet and a preparation method thereof. The cefuroxime axetil odor-masking pellet consists of an uncoated pellet containing the cefuroxime axetil and an odor-masking layer coating outside the uncoated pellet. The cefuroxime axetil odor-masking pellet overcomes the defect of bitter taste of the prior cefuroxime axetil tablets, and provides a novel cefuroxime axetil preparation which masks bitter taste, releases medicament rapidly and has stable quality.
Owner:湖南中南科伦药业有限公司 +1

Available memory space extension method and available memory space extension system of terminal equipment

The invention relates to an available memory space extension method and an available memory space extension system of terminal equipment. The available memory space extension method includes acquiring residual capacity of a local memory space after a file to be stored is received; if the residual capacity of the local memory space is smaller than the file to be stored, deleting files backed up to cloud equipment until the residual capacity of the local memory space is larger than the file to be stored, and storing the file to be stored into the local memory space. The available memory space extension method and the available memory space extension system of the terminal equipment have the advantages that synchronous backup and deletion of the files can be carried out within different time periods, and when the storage space is insufficient, backup of the files can be ensured and the files can be deleted directly to facilitate timely storage of the received file to be stored, so that release of the local memory space is accelerated greatly and storage convenience is improved.
Owner:GUANGZHOU SHIYUAN ELECTRONICS CO LTD

Preparation method and use of degradable polymer nano-microcapsules

The invention relates to a preparation method and a use of degradable polymer nano-microcapsules. The preparation method comprises the following steps of carrying out backflow deposition on an acrylic acid monomer to produce uncross-linked polymer nano-microspheres, carrying out backflow deposition to coat a disulfide bond cross-linked polymer shell layer on the surface of the uncross-linked polymer nano-microsphere by disulfide bond-containing N,N'-bis(acryloyl)cystamine as a cross-linking agent, transferring the prepared core-shell composite microspheres into ethanol or water, and carrying out uncross-linked polymer core etching to obtain the degradable polymer nano-microcapsules having monodispersity. The preparation method can be carried out fast, has simple aftertreatment processes, is free of an etching process adopting strong acid or strong alkali and is safe and efficient. After freeze-drying treatment, the degradable polymer nano-microcapsule can carry doxorubicin as a cancer-resistant drug and the cavity of the degradable polymer nano-microcapsule is further filled with perfluorohexane having ultrasonic response so that the degradable polymer nano-microcapsule is effectively used as an ultrasonic contrast agent and a drug carrier. The ultrasonic contrast agent can be fast decomposed to form very low molecular-weight linear molecules (Mn<5000) in the presence of glutathione or dithiothreitol as a reducing agent.
Owner:FUDAN UNIV

Alkynyl hydroxypropyl cellulose and preparation method and application of temperature-sensitive hydrogel of alkynyl hydroxypropyl cellulose

The invention discloses alkynyl hydroxypropyl cellulose and a preparation method and an application of a temperature-sensitive hydrogel of the alkynyl hydroxypropyl cellulose. In the invention, natural biology-based high-polymer hydroxypropyl cellulose is provided firstly, and is introduced into synthesis of a temperature-sensitive hydrogel material. The method for the temperature-sensitive hydrogel comprises the following steps of: (1) preparing azidopolycaprolactone-2-hydroxyethyl methylacrylate; (2) preparing poly(azidopolycaprolactone-2-hydroxyethyl methylacrylate-co-nitroisopropyl acrylamide); (3) preparing alkynyl hydroxypropyl cellulose; and (4) performing a click chemical reaction on the poly(azidopolycaprolactone-2-hydroxyethyl methylacrylate-co-nitroisopropyl acrylamide) and the alkynyl hydroxypropyl cellulose according to a certain proportion to obtain the temperature-sensitive hydrogel finally. The hydrogel provided by the invention has a unique structure and high mechanical strength, is biodegradable, and has a potential application value in the field of biological medicine.
Owner:GUANGZHOU CHEM CO LTD CHINESE ACADEMY OF SCI

Biological material for brain injury renovation and its preparing process

InactiveCN1927415AFast releaseFast and slow releaseCoatingsProsthesisInjury brainAdipic acid
The invention relates to a biological material used to recover hurt brain. Wherein, it uses transparent hyaluronic acid as raw material, guided by carbodiimide hydrochlorate (EDC), to use adipic acid adipoyl (ADH) to cross, to obtain the hyaluronic acid gel, as the carrier of graft antibody; and uses antibody solidification technique to graft the antibodies of axon growth restrain factor MAG, OMgp and Nogo-A to the hyaluronic acid gel, to be the antibody transfer system carrying special antibody and sensitive to pH value. The invention can be used to seal the never axon regeneration restrain factor of myelin and accelerate the regeneration of hurt brain organism.
Owner:首都医科大学北京神经科学研究所

Preparation for feather keratin membrane and use of feather keratin membrane as medicament carrier

The invention provides a method for preparing a feather keratin membrane, which belongs to the technical field of polymer processing. The method comprises the following steps of: dissolving feather keratin powder serving as raw material in alkali; then adjusting the pH value to between 7 and 14 with acid solution; and adding plasticizer into the mixture to form the membrane a culture dish. The method has the characteristics of simple process and low cost; and the keratin prepared by the method has biodegradability and good mechanical properties, is easy to peel, and can be used as the medicament carrier for the preparation of membrane medicament. Experiment shows that the membrane agent medicament prepared by taking the feather keratin membrane as the carrier have large loading capacity and high releasing speed.
Owner:NORTHWEST NORMAL UNIVERSITY
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