The invention discloses warm application powder for pain in neck, shoulders, waist and legs. The warm application powder is prepared from the following traditional Chinese medicines: medicinal stauntonia chinensis DC, radix angelicae pubescentis, rhizoma et radix notopterygii, paeonia veitchii lynch, cortex acanthopanacis, rhizoma drynariae, rhizoma chuanxiong, herba taxilli, flos carthami, unprocessed radix aconiti, unprocessed radix aconiti kusnezoffii, radix achyranthis bidentatae, herba menthae, radix angelicae dahuricae, herba lycopodii, radix gentianae macrophyllae, ramulus mori, herba taxilli, caulis spatholobi, ramulus cinnamomi, borneolum syntheticum, herba ephedrae, semen sinapis, radix notoginseng, radix paeoniae alba, rhizoma cibotii, eupolyphaga seu steleophaga, frankincense,myrrh, rhizoma corydalis, radix aucklandiae, shortstalk monkshood roots, radix puerariae, rhizoma polygoni cuspidati, rhizoma sparganii and rhizoma atractylodis. The warm application powder for pain in the neck, the shoulders, the waist and the legs provided by the invention has a wide adaption range, and has good treatment effects on cervical spondylopathy, frozen shoulder, lumbar disc herniation, knee osteoarthritis, hyperosteogeny and rheumatism, the overall response ratio is up to 95.9 percent, and the powder is convenient to use; through warm application, the pain stopping and treatment effects can be achieved, the powder is non-irritating to the skin, experience of patients is good, damage to the liver and the kidney is avoided through medicines for oral administration, pain of surgery of the patients is eliminated, and the treatment cost is low.