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Transdermal patch with functions of expelling wind and removing dampness and reducing swelling and easing pain and preparation method thereof

A technology for reducing swelling and pain, and a transdermal patch, which is applied in the directions of non-central analgesics, medical preparations containing active ingredients, anti-inflammatory agents, etc. Explosive and other problems, to achieve the effect of reducing toxic side effects, improving compliance, and reducing the number of administrations

Inactive Publication Date: 2010-06-23
广西方略药业集团有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the production process of traditional Chinese medicine paste at home and abroad is mainly solvent spreading method, which needs a lot of gasoline, high production cost, flammable and explosive, and easy to cause skin allergies. In order to overcome these shortcomings, new dosage forms are being studied at home and abroad. And production process, non-solvent type transdermal patch and water-based transdermal patch are research hotspots, although water-based transdermal patch does not have these difficulties of solvent method transdermal patch (or cataplasm), but Due to the volatilization of water and poor quality controllability, solvent-free transdermal patches (or cataplasms) are more popular

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0105] Prescription of Chinese medicine Tongzhongling extract (unit is weight):

[0106] Douye Jiulixiang 15g Sifang Wooden Skin 50g Hantao Leaf 50g

[0107] Mountain Turtle 35g Black Hair 40g Sumac 5g

[0108] Guoganglong 50g Big bark bone 5g Jackpot 5g

[0109] Guizhi 5g Small bark bone 5g Datouchen 5g

[0110] Niu Dali 5g Jiulixiang 5g Bamboo Leaf Pepper 10g

[0111] Fangji 10g Dafeng AI 15g Drynaria 10g

[0112] Xiaofeng AI 15g Woody Fragrance 15g Angelica dahurica 15g

[0113] Turmeric 2.5g Cinnabar Root 25g Angelica Vine 25g

[0114] Sweet Potato Vine 25g Zou Mafeng 25g Pig Tooth Soap 25g

[0115] Cyperus 25g Aqua Orchid 25g Pork belly veneer 50g

[0116] Milletweed 50g

[0117] Tongzhongling transdermal patch (or cataplasm) prescription (unit: weight):

[0118] Traditional Chinese medicine thick paste: 80g

[0119] Polyisobutylene: 160g

[0120] Rosin: 50g

[0121] Vaseline: 15g

[0122] Zinc oxide: 180g

[0123] Ice flakes: 7g

[0124] Camphor: 15g

[012...

Embodiment 2

[0131] Tongzhongling extract prescription (unit is weight):

[0132] Douye Jiulixiang 20g Sifang Wooden Skin 40g Han Tao Leaf 45g

[0133] Mountain Turtle 40g Black Hair 30g Sumac 8g

[0134] Guoganglong 40g Big bark bone 6g Jackpot 6g

[0135] Guizhi 6g Small bark bone 6g Datouchen 4g

[0136] Niu Dali 5g Jiulixiang 6g Bamboo Leaf Pepper 12g

[0137] Fangji 8g Dafeng AI 16g Drynaria 12g

[0138] Xiaofeng AI 15g Woody Fragrance 12g Angelica dahurica 16g

[0139] Turmeric 3g Cinnabar Root 28g Angelica Vine 26g

[0140] Sweet Potato Vine 30g Zoumafeng 26g Pig Tooth Soap 25g

[0141] Cyperus 20g Aqua Orchid 20g Pork belly veneer 40g

[0142] Milletweed 60g

[0143] Tongzhongling transdermal patch (or cataplasm) prescription (unit: weight):

[0144] Thick paste: 60g

[0145] Polyisobutylene: 180g

[0146] Carboxymethyl starch: 50g

[0147] Vaseline: 15g

[0148] Zinc oxide: 180g

[0149] Ice flakes: 6g

[0150] Camphor: 13g

[0151] Menthol: 18g

[0152] Preparati...

Embodiment 3

[0155] Tongzhongling extract prescription (unit is weight):

[0156] Douye Jiulixiang 18g Sifang Wooden Skin 45g Hantao Leaf 50g

[0157] Mountain Turtle 55g Black Hair 40g Sumac 6g

[0158] Guoganglong 55g Big bark bone 4g Jackpot 5g

[0159] Guizhi 4g Small bark bone 8g Datouchen 5g

[0160] Niu Dali 6g Jiulixiang 7g Bamboo Leaf Pepper 10g

[0161] Fangji 6g Dafeng AI 18g Drynaria Drynaria 10g

[0162] Xiaofeng AI 13g Woody Fragrance 12g Angelica dahurica 15g

[0163] Turmeric 4g Cinnabar Root 25g Angelica Vine 20g

[0164] Sweet Potato Vine 28g Zou Mafeng 23g Pig Tooth Soap 25g

[0165] Cyperus 20g Aqua Orchid 18g Pork belly veneer 45g

[0166] Milletweed 55g

[0167] Tongzhongling transdermal patch (or cataplasm) prescription (unit: weight):

[0168] Thick paste: 60g

[0169] Polyisobutylene: 180g

[0170] Carboxymethyl starch: 50g

[0171] Vaseline: 15g

[0172] Zinc oxide: 180g

[0173] Ice flakes: 6g

[0174] Camphor: 13g

[0175] Menthol: 18g

[0176] ...

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PUM

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Abstract

The invention relates to a transdermal patch (or poultice) with functions of expelling wind and removing dampness and reducing swelling and easing pain and a preparation method thereof; the transdermal patch is composed of a backlining layer, a medicine storage layer and an anti-sticking layer; the medicine storage layer comprises the following ingredients: 20-30 percent of framework material, 22-32 percent of tackifier, 25-35 percent of stuffing bulking agent, 6-13 percent of lubricating agent, and 6-13 percent of medicine, the medicine mainly comprises more than 30 kinds of extract prepared by traditional Chinese medicines, such as suberect spatholobus stem, spathodea campanulata, schefflerakwangsiensis, climbing entada, Ilex godajam dry skin, fissistigma polyanthum and the like, the medicines are pasted to obtain tongzhongling transdermal patch the according to the process steps and the mixing proportion; as no solvent is used in the production, the production cost is reduced by 1 / 3, the pesticide effect is improved, the drug administration times are reduced, the usage is convenient, cutaneous anaphylaxis is reduced, and the compliance of patients is improved; the tongzhongling transdermal patch has the effect of expelling wind and removing dampness and reducing swelling and easing pain and is clinically used for rheumatoid arthritis and traumatic injury.

Description

technical field [0001] The invention relates to a traditional Chinese medicinal preparation for external use, in particular to a traditional Chinese medicinal transdermal drug preparation (or cataplasm) capable of expelling wind and dampness, reducing swelling and relieving pain and a preparation method thereof. Background technique [0002] Traditional Chinese medicine is the traditional medicine of our country. The external treatment of internal diseases is one of the main principles of traditional Chinese medicine. The application therapy belongs to the external treatment method. The transdermal plaster of traditional Chinese medicine is one of the main dosage forms of the plaster therapy in the external treatment method, which has curative effect. It has the advantages of being accurate, safe and reliable, and having little side effects on the human body. The production of transdermal patches (or cataplasms) at home and abroad has a history of nearly 100 years. With the ...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/70A61P29/00A61P19/08A61K31/045A61K31/125
Inventor 杨进明王德武莫国飞
Owner 广西方略药业集团有限公司
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