Ointment capable of promoting blood circulation to remove blood stasis, diminishing inflammation and relieving pain and preparation method thereof
An anti-inflammatory and pain-relieving, blood-activating and stasis-removing technology, used in non-central analgesics, anti-inflammatory agents, pharmaceutical formulations, etc., can solve problems such as slow onset of action, long-term use, and inability to quickly relieve trauma pain and inflammation.
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Embodiment 1
[0029] Each composition and preparation method thereof in the first specific embodiment of the present invention are as follows:
[0030] 1) Matrix: 2 g gelatin, 3 g gum arabic, 0.2 g azone, 2.5 g polyethylene glycol 400, 2 g sodium polyacrylate, 2 g glycerin, 0.1 g zinc oxide, 5 ml water;
[0031]2) The raw material formula of the traditional Chinese medicine composition is as follows: Angelica 20 g, peach kernel 30 g, red peony root 30 g, frankincense 25 g, myrrh 25 g, earthworm 35 g, blood jellyfish 15 g, notoginseng 10 g, aconite 20 g , borneol 10 g; the preparation method is as follows: take the medicinal material according to the prescription, pulverize it into a coarse powder of about 20 meshes under a high-speed pulverizer, weigh 100 g of the coarse powder, add 2000 ml of 90% ethanol to an Erlenmeyer flask, and ultrasonically assist in dissolving Extract for 1 hour (repeat three times), filter with suction, combine three ethanol extracts, concentrate under reduced pres...
Embodiment 2
[0043] Each composition and preparation method thereof in the second specific embodiment of the present invention are as follows:
[0044] 1) Matrix: 2.5 g gelatin, 4 g gum arabic, 0.5 g azone, 3 g polyethylene glycol 400, 2.5 g sodium polyacrylate, 4 g glycerin, 0.3 g zinc oxide, 8 ml water;
[0045] 2) The raw material formula of the traditional Chinese medicine composition is as follows: Angelica 20 g, peach kernel 30 g, red peony root 30 g, frankincense 25 g, myrrh 25 g, earthworm 35 g, blood jellyfish 15 g, notoginseng 10 g, aconite 20 g And borneol 10 g, preparation method is as shown in embodiment 1.
[0046] 3) The preparation method of the cactus extract is as follows: Take 100g of the dried coarse powder of the cactus fleshy stem, add 2000ml of 80% ethanol solvent to soak overnight, extract by ultrasonic, filter and concentrate under reduced pressure to form a thick extract, and then the cactus ethanol extract is obtained, wherein the pH About 4.5, the active substa...
Embodiment 3
[0057] Each composition and preparation method thereof in the third specific embodiment of the present invention are as follows:
[0058] 1) Matrix: matrix gelatin 2.5 g, gum arabic 4 g, azone 0.5 g, polyethylene glycol 400 3 g, sodium polyacrylate 2.5 g, glycerin 4 g, zinc oxide 0.3 g, water 8ml
[0059] 2) The raw material formula of the traditional Chinese medicine composition is as follows: Angelica 20 g, peach kernel 30 g, red peony root 30 g, frankincense 25 g, myrrh 25 g, earthworm 35 g, blood jellyfish 15 g, notoginseng 10 g, aconite 20 g , borneol 10 g, the preparation method is as shown in Example 1.
[0060] 3) Cactus stock solution: as shown in Example 1 of the preparation method, the pH is about 5.5, the active substance is 1.52 g crude drug / ml in terms of crude drug, and the density is 1.29 g / ml.
[0061] 4) Prescription ratio in the preparation: traditional Chinese medicine composition: matrix = 1:5 (mass ratio); cactus stock solution: matrix = 1:5 (mas...
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