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Ointment capable of promoting blood circulation to remove blood stasis, diminishing inflammation and relieving pain and preparation method thereof

An anti-inflammatory and pain-relieving, blood-activating and stasis-removing technology, used in non-central analgesics, anti-inflammatory agents, pharmaceutical formulations, etc., can solve problems such as slow onset of action, long-term use, and inability to quickly relieve trauma pain and inflammation.

Inactive Publication Date: 2013-09-25
SICHUAN AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, traditional Chinese medicine preparations often have the disadvantages of slow onset and long-term use, and cannot quickly relieve pain and inflammation caused by trauma. Patients need to endure the pain of disease in the initial stage of treatment

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Each composition and preparation method thereof in the first specific embodiment of the present invention are as follows:

[0030] 1) Matrix: 2 g gelatin, 3 g gum arabic, 0.2 g azone, 2.5 g polyethylene glycol 400, 2 g sodium polyacrylate, 2 g glycerin, 0.1 g zinc oxide, 5 ml water;

[0031]2) The raw material formula of the traditional Chinese medicine composition is as follows: Angelica 20 g, peach kernel 30 g, red peony root 30 g, frankincense 25 g, myrrh 25 g, earthworm 35 g, blood jellyfish 15 g, notoginseng 10 g, aconite 20 g , borneol 10 g; the preparation method is as follows: take the medicinal material according to the prescription, pulverize it into a coarse powder of about 20 meshes under a high-speed pulverizer, weigh 100 g of the coarse powder, add 2000 ml of 90% ethanol to an Erlenmeyer flask, and ultrasonically assist in dissolving Extract for 1 hour (repeat three times), filter with suction, combine three ethanol extracts, concentrate under reduced pres...

Embodiment 2

[0043] Each composition and preparation method thereof in the second specific embodiment of the present invention are as follows:

[0044] 1) Matrix: 2.5 g gelatin, 4 g gum arabic, 0.5 g azone, 3 g polyethylene glycol 400, 2.5 g sodium polyacrylate, 4 g glycerin, 0.3 g zinc oxide, 8 ml water;

[0045] 2) The raw material formula of the traditional Chinese medicine composition is as follows: Angelica 20 g, peach kernel 30 g, red peony root 30 g, frankincense 25 g, myrrh 25 g, earthworm 35 g, blood jellyfish 15 g, notoginseng 10 g, aconite 20 g And borneol 10 g, preparation method is as shown in embodiment 1.

[0046] 3) The preparation method of the cactus extract is as follows: Take 100g of the dried coarse powder of the cactus fleshy stem, add 2000ml of 80% ethanol solvent to soak overnight, extract by ultrasonic, filter and concentrate under reduced pressure to form a thick extract, and then the cactus ethanol extract is obtained, wherein the pH About 4.5, the active substa...

Embodiment 3

[0057] Each composition and preparation method thereof in the third specific embodiment of the present invention are as follows:

[0058] 1) Matrix: matrix gelatin 2.5 g, gum arabic 4 g, azone 0.5 g, polyethylene glycol 400 3 g, sodium polyacrylate 2.5 g, glycerin 4 g, zinc oxide 0.3 g, water 8ml

[0059] 2) The raw material formula of the traditional Chinese medicine composition is as follows: Angelica 20 g, peach kernel 30 g, red peony root 30 g, frankincense 25 g, myrrh 25 g, earthworm 35 g, blood jellyfish 15 g, notoginseng 10 g, aconite 20 g , borneol 10 g, the preparation method is as shown in Example 1.

[0060] 3) Cactus stock solution: as shown in Example 1 of the preparation method, the pH is about 5.5, the active substance is 1.52 g crude drug / ml in terms of crude drug, and the density is 1.29 g / ml.

[0061] 4) Prescription ratio in the preparation: traditional Chinese medicine composition: matrix = 1:5 (mass ratio); cactus stock solution: matrix = 1:5 (mas...

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Abstract

The invention relates to an ointment capable of promoting blood circulation to remove blood stasis, diminishing inflammation and relieving pain and a preparation method thereof. The ointment is prepared from a traditional Chinese medicine composition, a cactus extract, methyl salicylate and a matrix and is brown-red and semitransparent. The ointment is mainly used for promoting blood circulation to remove blood stasis, diminishing inflammation, relieving pain, ect. According to the invention, traditional Chinese medicines and western medicines are effectively combined together, respective problems of traditional Chinese medicines and western medicines are overcome, and an active treatment effect is obtained.

Description

technical field [0001] The invention relates to an ointment for promoting blood circulation and removing blood stasis, reducing inflammation and relieving pain and a preparation method thereof, which belongs to the field of medicines. Background technique [0002] With the changes in the working environment and rhythm of life in modern society, and the aggravation of population aging, bruises, waist and knee pain caused by various factors affect people's health, daily life and work. Conventional western medicine treatment is only simple trauma management and symptomatic treatment. In addition to local anesthetics, antipyretic and analgesics are often used locally or systemically to relieve inflammation and pain in a short period of time, but often cause local skin irritation and gastrointestinal side effects . Although the effect is quick, it can only treat the symptoms but not the root cause. Soft tissue damage can only be repaired naturally by the body, and it will take ...

Claims

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Application Information

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IPC IPC(8): A61K36/889A61K36/896A61P29/00A61K31/045A61K35/56A61K31/618A61K35/62
Inventor 梁晓霞范巧佳潘燕
Owner SICHUAN AGRI UNIV
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