Fast dissolving orally consumable film

a consumable film, fast technology, applied in the direction of drug compositions, other medical devices, immunologic disorders, etc., can solve the problems of less convenient use of devices and compositions used in oral cleansing practices, wide compliance with this basic requirement, and difficulty or inconvenience in oral cleansing, etc., to achieve rapid dissolution in the mouth and extend the effect of

Inactive Publication Date: 2005-02-10
MCNEIL PPC INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0021] The invention provides a physiologically acceptable film, which is particularly well adapted to adhere to and rapidly dissolve in the mouth of a consumer. In a first embodiment of the invention, the film delivers at least one oral care agent, such as antimicrobial agents and salivary stimulants. The antimicrobial agents are effective against germs that cause hali

Problems solved by technology

Unfortunately, several factors conspire to prevent widespread compliance with this basic requirement of a good oral cleaning regimen.
Oral cleansing can be difficult or inconvenient at times, depending on the nature of the cleansing and the situation in which the cleansing must occur.
However, the devices and compositions used in oral cleansing practices are less convenient to use away from home, where bathroom facilities might be scarce, unavailable or unsanitary.
Although gums and lozenges have been formulated to achieve a variety of beneficial effects, they are not always socially acceptable.
Gums and mints are used over extended periods of time, and they require an amount of sucking or chewing action on the part of the consumer, which can be distracting, tedious and undesirable.
On the other hand, mo

Method used

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  • Fast dissolving orally consumable film
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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0149] Example 1 produced a film according to the invention having a blue-green tint, a mint odor and a refreshing mint taste.

examples 2-4

[0150] Examples 2-4 contain sorbitol, glycerin or both. These examples yielded products that easily broke off pieces, or were too moist and / or self-adhering. However they did produce films that rapidly dissolved in the oral cavity with a refreshing mint taste.

examples 5-6

[0151] Examples 5 and 6 removed glycerin and sorbitol. The resultant films did not stick together during processing and packaging and were more moisture stable over a long time frame.

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Abstract

Physiologically acceptable films, including edible films, are disclosed. The films include a water soluble film-forming polymer such as pullulan. Edible films are disclosed that include pullulan and antimicrobially effective amounts of the essential oils thymol, methyl salicylate, eucalyptol and menthol. The edible films are effective at killing the plaque-producing germs that cause dental plaque, gingivitis and bad breath. The film can also contain pharmaceutically active agents. Methods for producing the films are also disclosed.

Description

[0001] This application claims the benefit of U.S. patent application Ser. No. 10 / 418,368, filed on Apr. 17, 2003, which claims the benefit of U.S. patent application Ser. No. 09 / 395,104, filed on Sep. 14, 1999, which claims the benefit of U.S. Provisional Application 60 / 101,798, filed Sep. 25, 1998 the entirety of which is hereby incorporated by reference as if fully set forth herein.FIELD OF THE INVENTION [0002] This invention relates to fast dissolving orally consumable films. The films are used to deliver breath deodorizing agents, antimicrobial agents and salivary stimulants to the oral cavity. The films can also be used to deliver pharmaceutically active agents. BACKGROUND OF THE INVENTION [0003] In a more perfect world, people would thoroughly cleanse their mouths after each meal as part of their routine oral hygienic practices. Unfortunately, several factors conspire to prevent widespread compliance with this basic requirement of a good oral cleaning regimen. [0004] Oral cle...

Claims

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Application Information

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IPC IPC(8): A61K8/00A61K9/68A61K8/02A61K8/21A61K8/34A61K8/37A61K8/41A61K8/43A61K8/44A61K8/49A61K8/64A61K8/65A61K8/73A61K8/81A61K8/86A61K8/92A61K9/00A61K9/14A61K9/20A61K9/28A61K9/70A61K31/00A61K31/045A61K31/30A61K31/405A61K31/415A61K31/44A61K31/485A61K31/60A61K31/7012A61K31/715A61K38/38A61K45/06A61K47/00A61K47/10A61K47/14A61K47/32A61K47/38A61M37/00A61P1/12A61P25/00A61P25/04A61P29/00A61P31/04A61Q11/00
CPCA23G3/50A61K8/0216A61K8/34A61K8/347A61K8/37A61K8/416A61K8/43A61K8/44A61K8/4973A61K8/64A61K8/645A61K8/65A61K8/73A61K8/731A61K8/732A61K8/733A61K8/736A61K8/8129A61K8/8147A61K8/8152A61K8/8176A61K8/86A61K8/922A61K9/0056A61K9/006A61K9/2072A61K9/7007A61K31/00A61Q11/00A61K8/21A61P1/02A61P1/04A61P1/12A61P11/10A61P11/14A61P25/00A61P25/04A61P29/00A61P31/04A61P37/00A61K8/0208A61P1/00A61P11/00A61P31/00A61K9/70
Inventor SPENCE LEUNG, SAU-HUNGLEONE, ROBERT S.KUMAR, LORI D.KULKARNI, NEEMASORG, ALBERT F.
Owner MCNEIL PPC INC
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