Traditional Chinese medicine composition for treating pelvic inflammatory disease as well as enema granules and application thereof

Abstract

The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating pelvic inflammatory diseases and enema granules and application thereof. The invention discloses a traditional Chinese medicine composition for treating pelvic inflammatory diseases and enema granules thereof. The traditional Chinese medicine composition is prepared from the following components: 25-35 parts of dandelion, 10-20 parts of rhizoma sparganii, 15-25 parts of spina gleditsiae, 10-20 parts of curcuma zedoary, 25-35 parts of salvia chinensis, 25-35 parts of raw salvia miltiorrhiza, 15-25 parts of herba patriniae, 15-25 parts of radix bupleuri, 15-25 parts of beautiful sweetgum fruit, 15-25 parts of red paeony root, 25-35 parts of sargentgloryvine stem, 10-20 parts of radix clematidis, 15-25 parts of honey and bran fried bighead atractylodes rhizome, 15-25 parts of fried cowherb seed and 15-25 parts of vinegar corydalis tuber. The traditional Chinese medicine composition for treating the pelvic inflammatory disease and the enema granules thereof have the effects of clearing away heat and toxic materials, promoting blood circulation to remove blood stasis and relieving swelling and pain, and the purpose of treating the pelvic inflammatory disease is achieved.

Description

Technical Field

[0001] The present invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition for treating pelvic inflammatory disease and its enema granules and uses. Background Art

[0002] Pelvic inflammatory disease (PID) refers to a group of infectious diseases of the female upper reproductive tract, mainly including endometritis, salpingitis, tubo-ovarian abscess, pelvic peritonitis, etc. Pelvic inflammatory disease often occurs in women of childbearing age. If it is not treated promptly and thoroughly, it can lead to infertility, tubal pregnancy, chronic pelvic pain, and repeated attacks of inflammation, which seriously affect women's reproductive health and increase the family and socioeconomic burden. At present, Western medicine mostly uses antibiotics to treat pelvic inflammatory disease. It has significant efficacy for acute pelvic inflammatory disease, but it is not effective for tissue adhesions and blood circulation disorders caused by chronic inflammation. In addition, patients have low tolerance, and long-term use of antibiotics can easily lead to drug resistance, affecting the clinical treatment effect. Traditional Chinese medicine treatment methods have shown good results in the treatment of pelvic inflammatory disease, making up for the shortcomings of current Western medicine treatment methods.

[0003] Traditional Chinese Medicine believes that the occurrence of pelvic inflammatory disease is closely related to exogenous damp-heat, endogenous blood stasis and toxicity, and organ dysfunction. It falls into the category of "leucorrhea", "abdominal pain", and "mass-mass". The causes can be summarized as follows: ① Exogenous damp-heat and blood stasis: During menstruation, after childbirth, when the uterus is open, or after uterine cavity operation, damp-heat evil takes advantage of the opportunity to invade, mingling with blood, blocking the uterus and uterine vessels, forming "damp-heat, blood stasis and toxicity". Exogenous toxic evil (such as heat toxins) invades the lower part of the body, burning the blood vessels. If blood circulation is not smooth, it will cause blood stasis, and the combination of toxicity and blood stasis will cause local inflammation. ② Endogenous blood stasis: This includes emotional stagnation (liver depression) leading to qi stagnation and blood circulation stagnation; or cold stagnation and blood stasis, leading to blood stasis in the uterus, which causes pain; and spleen dysfunction, endogenous phlegm and dampness, which mingles with qi and blood, blocking the pelvic meridians, causing inflammation and tissue adhesions. ③ Deficiency of the body and retention of pathogenic factors: Spleen deficiency or kidney deficiency, insufficient Qi and blood, low disease resistance, leading to repeated attacks of inflammation and turning it into a chronic disease.

[0004] The Chinese medicine composition and enema granules provided by the present invention are directed to the characteristics of pelvic inflammatory disease. With Radix Sanguisorbae and Radix Patriniae sophorae flavescentis for clearing away heat and toxic substances and reducing swelling as the main ingredients, with Herba Taraxaci, Spina Gleditsiae, and Radix Lithospermi as the main ingredients for reducing swelling and dispersing stagnation, with Rhizoma Trigonellae, Rhizoma Curcumae, Radix Salviae Miltiorrhizae, and Radix Paeoniae Rubra as the ministers for promoting blood circulation and removing blood stasis, with Fructus Clematis, Rhizoma Clematis, and Rhizoma Corydalis as the auxiliary ingredients for promoting blood circulation and removing blood stasis, and with Radix Bupleuri and Rhizoma Atractylodis Macrocephalae stir-fried with honey bran for promoting menstruation and relieving pain, and with Radix Bupleuri and Rhizoma Atractylodis macrocephalae stir-fried with honey bran for soothing the liver and strengthening the spleen, and with all the medicines introduced into the liver and spleen meridians, directly reaching the affected area, the whole prescription plays the role of clearing away heat and toxic substances, promoting blood circulation and removing blood stasis, reducing swelling and relieving pain. At present, among the liquid preparations for treating pelvic inflammatory disease clinically, enema with Chinese herbal medicine decoction is the main ingredient, but the disadvantages are that it is not easy to carry, easily deteriorates, and has poor patient compliance. The technical problem to be solved by the present invention is to provide a Chinese medicine enema granule for treating pelvic inflammatory disease with remarkable efficacy, easy to carry, and easy to preserve. Summary of the Invention

[0005] The first object of the present invention is to provide a traditional Chinese medicine composition for treating pelvic inflammatory disease, which has significant effect in treating pelvic inflammatory disease, few toxic and side effects, and good patient tolerance.

[0006] The second object of the present invention is to provide a Chinese medicine composition enema granule for treating pelvic inflammatory disease, which has good efficacy, is easy to carry and store.

[0007] The third object of the present invention is to provide a use of the traditional Chinese medicine composition and enema granules thereof in the preparation of medicines for treating pelvic inflammatory diseases.

[0008] In order to achieve the above object, the technical solution adopted by the present invention is as follows:

[0009] A first aspect of the present invention provides a traditional Chinese medicine composition for treating pelvic inflammatory disease and an enema granule thereof, which is prepared from the following components: 25-35 parts of dandelion, 10-20 parts of trigonosciadium japonicum, 15-25 parts of gleditsia thorn, 10-20 parts of zedoaria, 25-35 parts of lithospermum officinale, 25-35 parts of raw salvia miltiorrhiza, 15-25 parts of patrinia ulmoides, 15-25 parts of bupleurum, 15-25 parts of rhizoma liquidambar formosana, 15-25 parts of red peony root, 25-35 parts of saffron vine, 10-20 parts of clematis root, 15-25 parts of stir-fried atractylodes macrocephala with honey bran, 15-25 parts of stir-fried vaccaria segetalis, and 15-25 parts of vinegar-corydalis yanhusuo.

[0010] Preferably, the traditional Chinese medicine composition for treating pelvic inflammatory disease and its enema granules are made from the following components: 30 parts of dandelion, 15 parts of trigonosciadium japonicum, 20 parts of gleditsia thorn, 15 parts of zedoaria, 30 parts of lithospermum officinale, 30 parts of raw salvia miltiorrhiza, 20 parts of patrinia suspensa, 20 parts of bupleurum, 20 parts of rhizoma liquidambar formosana, 20 parts of red peony root, 30 parts of safflower vine, 15 parts of clematis root, 20 parts of stir-fried atractylodes macrocephala with honey bran, 20 parts of stir-fried vaccaria segetalis, and 20 parts of vinegar-corydalis yanhusuo.

[0011] Among the above raw material components, the efficacy and pharmacological effects of each Chinese herbal raw material are as follows:

[0012] Dandelion: Clears heat and detoxifies, reduces swelling and resolves stagnation, and acts as a diuretic and relieving stranguria. It is used for boils, breast abscesses, scrofula, conjunctivitis, sore throat, lung abscesses, intestinal abscesses, damp-heat jaundice, and painful stranguria caused by heat. It has the effects of clearing heat and detoxifying, reducing swelling and resolves stagnation, and acting as a diuretic and relieving stranguria. Modern pharmacological research has found that dandelion also has anti-tumor, anti-inflammatory, antibacterial, hypoglycemic, and antioxidant properties.

[0013] Trigonosciadium japonicum: Promotes blood circulation and qi circulation, eliminates stagnation and relieves pain. It is used to treat lumps and masses, dysmenorrhea, amenorrhea due to blood stasis, chest pain, and bloating and pain caused by food stagnation. Modern pharmacological research has found that Trigonosciadium japonicum has anti-thrombotic, anti-inflammatory, analgesic, and anti-tumor effects.

[0014] Soapberry thorn: Reduces swelling, expels toxins, drains pus, and kills insects. It's used for carbuncles in their early stages or when pus forms but doesn't break; it's also used externally for scabies, leprosy, and ringworms. Soapberry thorn has antibacterial, anti-allergic, and immunomodulatory properties.

[0015] Curcuma: Promotes qi and dissolves blood, eliminates stagnation and relieves pain. Used for abdominal masses, blood stasis, amenorrhea, chest pain, and bloating and pain caused by food stagnation.

[0016] Lithospermum officinale: promotes blood circulation and removes blood stasis, clears away heat and dampness, disperses stagnation and reduces swelling. Used for irregular menstruation, dysmenorrhea, amenorrhea, metrorrhagia, bloody stool, jaundice due to damp heat, bloody dysentery due to heat toxins, painful stranguria, leukorrhea, rheumatic bone pain, scrofula, sores, and mastitis.

[0017] Raw Salvia miltiorrhiza: Promotes blood circulation, dispels blood stasis, promotes menstruation and relieves pain, clears the heart and relieves restlessness, cools blood and eliminates carbuncle. It is used to treat chest pain, abdominal pain, flank pain, accumulation of masses, pain due to heat rheumatic arthritis, restlessness and insomnia, menstrual irregularities, dysmenorrhea, amenorrhea, and sores and swelling. It has anti-atherosclerotic, anti-hyperlipidemic, anti-hypertensive, myocardial cell protective, anti-inflammatory, anti-tumor, antioxidant, and anti-fibrosis effects.

[0018] Subaijiang: Clears the liver and improves eyesight, harmonizes the middle and eliminates dampness, detoxifies and reduces swelling. Used for red and swollen eyes, abdominal distension and pain, hypochondriac pain, intestinal carbuncle, edema, leucorrhea, sores, furuncles and carbuncle swelling.

[0019] Bupleurum: Dispels heat, soothes liver qi, relieves depression, and elevates Yang Qi. It is used for colds, fever, alternating chills and fever, chest and flank pain, irregular menstruation, uterine prolapse, and rectal prolapse.

[0020] Rhizoma Lulutong: dispels wind and activates collaterals, promotes diuresis, and regulates menstruation. Used for joint pain, numbness and cramps, edema, oligolactosis, and amenorrhea.

[0021] Red Peony Root: Clears heat and cools blood, dissipates blood stasis and relieves pain. Used for heat invading the blood, fever-induced rashes, hematemesis and epistaxis, red and swollen eyes, liver depression and flank pain, amenorrhea and dysmenorrhea, abdominal pain due to lumps and injuries, carbuncles and ulcers.

[0022] Sargentodoxae: Clears away heat and detoxifies, promotes blood circulation, dispels wind and relieves pain. Used for abdominal pain caused by intestinal carbuncle, ulcers caused by heat toxins, amenorrhea, dysmenorrhea, swelling and pain caused by falls, and rheumatic pain.

[0023] Clematidis: dispels rheumatism and dredges meridians. Used for rheumatic pain, numbness of limbs, muscle spasms, and difficulty in flexion and extension.

[0024] Stir-fried Atractylodes macrocephala with honey bran: Strengthens the spleen and replenishes Qi, eliminates dampness and promotes diuresis, stops sweating, and stabilizes the fetus. Used for spleen deficiency, poor appetite, abdominal distension and diarrhea, phlegm and fluid retention, dizziness and palpitations, edema, spontaneous sweating, and restless fetus.

[0025] Stir-fried Vaccaria: Promotes blood circulation and menstruation, promotes lactation and reduces swelling, and promotes diuresis and relieves stranguria. It is used for amenorrhea, dysmenorrhea, milk retention, mastitis, swelling and pain, and stranguria.

[0026] Vinegar-coated Corydalis: Promotes blood circulation, promotes qi circulation, and relieves pain. Used for chest, flank, and abdominal pain, chest pain, heart pain, amenorrhea, dysmenorrhea, postpartum blood stasis, and swelling and pain due to falls.

[0027] The traditional Chinese medicine composition provided by the present invention uses Sargentodoxae and Patriniae sutchuenensis as main ingredients for clearing away heat, detoxicating and relieving swelling, uses Taraxacum mongolicum, Gleditsia chinensis, and Lithospermum officinale for relieving swelling and dispersing nodules, uses Trillium, Curcuma zedoaria, raw Salvia miltiorrhiza, and Paeonia lactiflora for promoting blood circulation and removing blood stasis as auxiliary ingredients, uses Rhizoma Lulutong, stir-fried Vaccaria segetalis, Clematidis, and Corydalis yanhusuo for promoting menstruation and relieving pain, uses Radix Bupleuri and stir-fried Atractylodes macrocephala with honey bran for soothing the liver and strengthening the spleen, and guides all the medicines into the liver and spleen meridians to directly reach the affected area, so that the whole formula has the effects of clearing away heat, detoxicating, promoting blood circulation and removing blood stasis, and reducing swelling and relieving pain.

[0028] The second aspect of the present invention provides a traditional Chinese medicine enema granule, which is prepared from the traditional Chinese medicine enema composition.

[0029] The third aspect of the present invention provides a use of the traditional Chinese medicine enema granules in preparing a medicine for treating pelvic inflammatory disease.

[0030] The pelvic inflammatory disease refers to a group of infectious diseases of the female upper reproductive tract, mainly including endometritis, salpingitis, tubo-ovarian abscess, and pelvic peritonitis.

[0031] Due to the adoption of the above technical solution, the present invention has the following advantages and beneficial effects: the Chinese medicine enema granules for treating pelvic inflammatory disease provided by the present invention have the effects of clearing away heat and detoxifying, promoting blood circulation and removing blood stasis, and reducing swelling and relieving pain, thereby achieving the purpose of treating pelvic inflammatory disease. Compared with the use of Western medicine alone, it is more effective, has fewer toxic and side effects, improves patient compliance, and is unlikely to develop drug resistance. In addition, the Chinese medicine enema granules provided by the present invention are easy to carry and store. The Chinese medicine enema granules for treating pelvic inflammatory disease of the present invention have significant efficacy, few toxic and side effects, and are well tolerated by patients. DETAILED DESCRIPTION

[0032] In order to explain the present invention more clearly, the present invention is further described below in conjunction with preferred embodiments. Those skilled in the art should understand that the following specific description is illustrative rather than restrictive and should not be used to limit the scope of protection of the present invention.

[0033] Example 1

[0034] A traditional Chinese medicine enema composition for treating pelvic inflammatory disease is prepared from the following components: 30g of dandelion, 15g of trigonosciadium root, 20g of gleditsia spinulosa, 15g of zedoaria, 30g of lithospermum officinale, 30g of raw salvia miltiorrhiza, 20g of patrinia suzanth, 20g of bupleurum root, 20g of fennel, 20g of red peony root, 30g of safflower vine, 15g of clematis root, 20g of stir-fried atractylodes macrocephala with honey bran, 20g of stir-fried vaccaria segetalis, and 20g of vinegar-corydalis. The weighed medicinal materials are placed in a casserole, 1000ml of water is added, stirred evenly, and soaked for 1 hour. The mixture is first boiled over high heat, then simmered over low heat for about 1 hour, and the medicinal liquid is filtered out. 1000ml of water is added to the filtrate residue and decocted a second time. After the mixture is boiled, simmered over low heat for about 1 hour, and the medicinal liquid is filtered out. Combine the two solutions to make approximately 200ml of enema. If the solution exceeds 200ml, further decoct and concentrate. If it is less than 200ml, add boiling water to 200ml and stir thoroughly. Pour the solution into a disposable enema bag. Perform the enema once daily, keeping the solution temperature between 39-41°C.

[0035] Example 2

[0036] A Chinese medicine enema granule for treating pelvic inflammatory disease is prepared from the following components: 600g of Herba Taraxaci, 300g of Rhizoma Trigonidis, 400g of Spina Gleditsiae, 300g of Rhizoma Curcumae, 600g of Rhizoma Lithospermi, 600g of Raw Salvia Miltiorrhiza, 400g of Patrinia Root, 400g of Radix Bupleuri, 400g of Fructus Clematis, 400g of Radix Paeoniae Rubra, 600g of Ceratoniae Dahuricae, 300g of Radix Clematidis, 400g of Rhizoma Atractylodis Macrocephalae stir-fried with honey bran, 400g of Rhizoma Vaccariae, and 400g of Rhizoma Corydalis with vinegar. The weighed medicinal materials are mixed evenly and placed in an extraction container. 20,000ml of water is added, stirred evenly, and soaked for 1 hour. The mixture is first boiled over high heat, then simmered over low heat for about 60 minutes, and the medicinal liquid is filtered out. 20,000ml of water is added to the filter residue and decocted a second time. The mixture is then boiled over high heat, then simmered over low heat for about 30 minutes, and the medicinal liquid is filtered out. The two medicinal solutions are combined and concentrated into an extract, which is spray-dried and granulated to obtain the Chinese medicine enema granules.

[0037] Instructions: Take 10 grams of the Chinese herbal enema granules of this invention per bag and pour the granules into a glass container. Dissolve the granules with 100 mL of hot water and shake the glass bottle to completely dissolve the granules. Once the liquid has cooled to 39-41°C, pour the liquid into a disposable enema bag.

[0038] Enema precautions: During contraception, enema should be performed from the end of menstruation to the onset of the next menstrual period. During pregnancy preparation, enema should be performed from the end of menstruation to the day of ovulation. Before enema, empty your bowels and bladder. Lie on your side in bed with your knees as close to your abdomen as possible and your buttocks close to the edge of the bed, fully exposing your anus. You or a family member should slowly insert the tip of the anal canal 10-15cm from the anus into the rectum. Turn on the enema. After completing the Chinese medicine enema, try to lie on your side for 20-30 minutes to allow the medicine to be fully absorbed. If you do not feel any discomfort, you do not need to use the toilet. If you feel the urge to defecate, go to the toilet to empty the medicine.

[0039] To further illustrate the effect of the Chinese medicine composition enema in the treatment of pelvic inflammatory disease, a retrospective analysis was conducted on 106 patients diagnosed with pelvic inflammatory disease who used the Chinese medicine composition enema from 2018 to 2024, and their clinical efficacy and adverse reactions were analyzed.

[0040] 1) Clinical Data

[0041] Inclusion criteria: Western medical diagnosis consistent with the diagnosis of pelvic inflammatory disease in the Journal of Obstetrics and Gynecology, and Traditional Chinese Medicine syndrome differentiation consistent with the blood stasis and dampness obstruction type in the "Guiding Principles for Clinical Research of New Chinese Medicines (Trial)." Age 18-55 years.

[0042] Exclusion criteria: pregnant or lactating women; women with allergic constitution or allergies to multiple drugs; women with pelvic tuberculosis, endometriosis, etc.; women who have taken related drugs within 4 weeks of using this enema, making it difficult to judge the efficacy.

[0043] A retrospective analysis was conducted on 106 patients with pelvic inflammatory disease who used the Chinese medicine composition enema according to the above criteria from 2018 to 2024. The Chinese medicine enema was used once a day, with one month as a course of treatment, and was discontinued during menstruation.

[0044] 2) Criteria for determining efficacy

[0045] According to the criteria for judging the efficacy of pelvic inflammatory disease in the "Obstetrics and Gynecology of Integrated Traditional Chinese and Western Medicine":

[0046] Recovery: clinical symptoms disappear, and there is no pelvic effusion or mass;

[0047] Markedly effective: Clinical symptoms basically disappear, gynecological examination shows that the mass is reduced, and adhesions and tenderness of the uterus and adnexa are alleviated;

[0048] Ineffective: The above criteria are not met and there is no improvement in symptoms and signs.

[0049] Total effective rate = [(number of cured cases + number of effective cases) / total number of cases] × 100%

[0050] 3) Clinical treatment results are shown in the following table:

[0051] Table 1 Treatment effects of 106 patients

[0052] get well Significantly effective invalid Total number of cases Total effective number Number of cases 25 73 8 106 98 Proportion 23.58％ 68.87％ 7.55％ 100％ 92.45％

[0053] The results of the investigation and research showed that among 106 patients who were treated with this Chinese medicine enema, 25 were clinically cured, 73 were significantly effective, and 8 were ineffective, with an overall effective rate of 92.45%.

[0054] Typical clinical cases

[0055] Case 1: Ms. Shen, 36 years old, presented with lower abdominal pain and menstrual irregularities. Preoperative hysteroscopy revealed a regular uterine cavity with approximately 1.0 cm long muscular adhesions on both sides. The anterior endometrium was flaky and had visible inflammatory exudates. The endometrium was pale and had a few glandular openings. Western medicine diagnosis: pelvic inflammatory disease and endometritis. Traditional Chinese medicine name: pelvic inflammatory disease; Traditional Chinese medicine syndrome: damp-heat stasis syndrome. A Chinese herbal enema composition according to the present invention was administered: 30 g of Taraxacum mongolicum, 15 g of Trigonum multiflorum, 20 g of Gleditsia sinensis, 15 g of Curcuma zedoaria, 30 g of Lithospermum officinale, 30 g of Raw Salvia miltiorrhiza, 20 g of Patrinia suspensa, 20 g of Bupleurum chinense, 20 g of Fructus Smilacis Glabrae, 20 g of Paeonia lactiflora, 30 g of Sargentodoxae chinensis, 15 g of Clematidis radix, 20 g of honey-braised Atractylodes macrocephala, 20 g of stir-fried Vaccaria segetalis, and 20 g of vinegar-cured Corydalis yanhusuo. Place the above herbs in a casserole, add 1000ml of water, and soak for 1 hour. Bring to a boil over high heat, then simmer for 1 hour over low heat. Filter the liquid. Add 1000ml of water to the residue and boil it a second time. Filter the liquid. Combine the two liquids to make about 200ml of enema. Pour the liquid into a disposable enema bag. During enema, control the liquid temperature at 39-41°C. Perform enema once every night for a total of 30 days, with a 5-day break due to menstruation. About 10 days after enema, the patient's abdominal pain was significantly relieved. A follow-up call 3 months after the end of treatment showed that the patient had no lower abdominal pain.

[0056] Case 2: Ms. Geng, 29 years old, presented with lower abdominal pain, uterine neoplasms, and obstructed fallopian tubes. Ultrasound examination revealed pelvic effusion. Western medicine diagnosis: pelvic inflammatory disease. Traditional Chinese medicine name: pelvic inflammatory disease; Traditional Chinese medicine syndrome: damp-heat stasis. She was given a Chinese herbal enema composition comprising 30g of Taraxacum mongolicum, 15g of Trigonum multiflorum, 20g of Gleditsia sinensis, 15g of Curcuma zedoaria, 30g of Lithospermum officinale, 30g of raw Salvia miltiorrhiza, 20g of Patrinia suspensa, 20g of Bupleurum chinense, 20g of Fructus Smilacis Glabrae, 20g of Paeonia lactiflora, 30g of Sargentodoxae chinensis, 15g of Clematidis, 20g of stir-fried Atractylodes macrocephala with honey bran, 20g of stir-fried Vaccaria segetalis, and 20g of Corydalis yanhusuo with vinegar. Enemas were administered once every night for a total of 28 days. After 15 days of using this enema composition, the patient's abdominal pain and other symptoms had significantly improved. One week after the end of treatment, a follow-up ultrasound examination revealed no pelvic effusion.

[0057] The above description is merely a preferred embodiment of the present invention and does not constitute any form of limitation to the present invention. Although the present invention has been disclosed as above in terms of a preferred embodiment, it is not intended to limit the present invention. Any technician familiar with this patent can make slight changes or modifications to equivalent embodiments using the above technical content without departing from the scope of the technical solution of the present invention. However, any simple modifications, equivalent changes, and modifications made to the above embodiments based on the technical essence of the present invention without departing from the content of the technical solution of the present invention are still within the scope of the solution of the present invention.

Claims

1. A Chinese medicine composition for treating pelvic inflammatory disease, characterized in that: Including dandelion, Trigonosciadium japonicum, Sophora flavescens, Curcuma zedoaria, Lithospermum officinale, raw Salvia miltiorrhiza, Patrinia serrata, Bupleurum chinense, Smilax glabra, Paeonia lactiflora, Sargentodoxae, Clematidis, stir-fried Atractylodes macrocephala with honey and bran, stir-fried Vaccaria segetalis, and Corydalis yanhusuo with vinegar.

2. The Chinese medicine composition for treating pelvic inflammatory disease according to claim 1, characterized in that The invention is prepared from the following components: 25-35 parts of dandelions, 10-20 parts of trigonosciadium japonicum, 15-25 parts of gleditsia thorns, 10-20 parts of zedoaria, 25-35 parts of lithospermum officinale, 25-35 parts of raw salvia miltiorrhiza, 15-25 parts of patrinia ulmoides, 15-25 parts of bupleurum, 15-25 parts of rhizoma liquidambar formosanae, 15-25 parts of red peony root, 25-35 parts of saffron vine, 10-20 parts of clematis root, 15-25 parts of stir-fried atractylodes macrocephala with honey bran, 15-25 parts of stir-fried vaccaria segetalis, and 15-25 parts of vinegar-corydalis yanhusuo.

3. The Chinese medicine composition for treating pelvic inflammatory disease according to claim 1, characterized in that The traditional Chinese medicine composition for treating pelvic inflammatory disease is prepared from the following components: 30 parts of dandelion, 15 parts of trigonosciadium japonicum, 20 parts of gleditsia thorn, 15 parts of zedoaria, 30 parts of lithospermum officinale, 30 parts of raw salvia miltiorrhiza, 20 parts of patrinia ulmoides, 20 parts of bupleurum, 20 parts of rhizoma liquidambar formosana, 20 parts of red peony root, 30 parts of saffron vine, 15 parts of clematis root, 20 parts of stir-fried atractylodes macrocephala with honey bran, 20 parts of stir-fried vaccaria segetalis, and 20 parts of vinegar-corydalis yanhusuo.

4. An enema of the Chinese medicine composition according to any one of claims 1 to 3, characterized in that: The preparation method of the Chinese medicine enema composition comprises the following steps: weighing the raw materials by weight, placing them in a clay pot, adding 1000 mL of water, stirring and soaking them for 1 hour, first boiling them over high heat, then decocting them over low heat for 1 hour, and filtering the medicinal liquid; adding 1000 mL of water to the filter residue, decocting them a second time, then boiling them, then decocting them over low heat for 1 hour, and filtering the medicinal liquid. The two decoctions are combined, allowed to stand, and the precipitate is filtered out. 200 mL of the medicinal liquid is then dispensed to obtain the Chinese medicine enema composition for treating pelvic inflammatory disease.

5. A Chinese medicine enema granule for treating pelvic inflammatory disease, characterized in that: A Chinese medicine composition comprising any one of claims 1 to 3.

6. The Chinese medicine enema granules according to claim 5, characterized in that The preparation method of the Chinese medicine enema granules comprises the following steps: (1) weighing dandelion, trifoliate green, soapberry thorn, zedoaria, lithospermum officinale, raw salvia miltiorrhiza, patrinia ulmoides, bupleurum, fennel, red peony root, safflower, clematis root, honey bran fried atractylodes, fried vaccaria, vinegar corydalis yanhusuo respectively according to weight parts, and setting aside; (2) mixing the above raw materials evenly, adding 10 times of water and boiling twice, filtering and extracting twice, combining the filtrates and concentrating them into extracts, and setting aside; (3) combining the extracts described in step (2), spray drying and granulating, so as to obtain the Chinese medicine enema granules.

7. The preparation method according to claim 6, characterized in that In the step (2), the amount of water added is 8 to 12 times the weight of the medicinal material; the decoction time each time is 45 to 75 minutes; and the relative density of the concentrated medicinal liquid extract measured at 70° C. to 80° C. is 1.10 to 1.

30.

8. A pharmaceutical preparation comprising the Chinese medicine composition and granules thereof as claimed in any one of claims 1 to 7 as active ingredients.

9. Use of the traditional Chinese medicine composition and granules thereof according to any one of claims 1 to 7 in the preparation of medicines for treating pelvic inflammatory diseases.