Geranium strictipes effective part preparation and medical use of geranium strictipes for preventing and curing colonitis

An effective part, the technology of Burnet burnet, applied in the field of medicine, can solve problems such as difficulty in timing, long-term administration according to the amount, stimulation and injury of gastric mucosa, etc., and achieve good results, clear industrialization prospects, and low sample loss.
CN102688263BInactive Publication Date: 2014-02-12DALI UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
DALI UNIV
Publication Date
2014-02-12
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to Geranium strictipes effective part preparation and medical use of the Geranium strictipes for preventing and curing colonitis. The extract of the Geranium strictipes effective part provided by the invention is refined from Yi nationality's medicine Geshanxiao through macroreticular resin. Geshanxiao is dried roots of geranium strictipes R. Knuth which belongs to geraniaceae geranium wilfordii. According to the invention, a rat acetic acid caused ulcerative colitis model is adopted for observing influences on relevant biochemical criterions of common clinical symptoms, pathomorphology and oxidative damage by the Geranium strictipes effective part. As shown in the experimental results, the Geranium strictipes effective part has certain therapeutical effect on the acetic acid caused ulcerative colitis rat model, and can ameliorate clinical symptoms thereof. Therefore, the Geranium strictipes effective part can be expected and applied in preparation of drugs capable of preventing and curing the ulcerative colitis.
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Description

technical field

[0001] The invention relates to the technical field of medicine, in particular, the invention relates to an effective part of Burnet burnet and its preparation method and medicinal use. The effective part is prepared from Geshanxiao, a herbal medicine commonly used by Bai and Yi nationalities in Yunnan, through a modern extraction process, has obvious anti-ulcerative colitis effects, and can be used to prepare health products or medicines for preventing and treating ulcerative colitis. Background technique

[0002] Ulcerative colitis (UC) is a chronic non-specific intestinal inflammatory disease of unknown etiology that mainly involves the rectum, colonic mucosa and submucosa. Chronic inflammation and ulceration of the colonic mucosa are the main pathological features. It is generally believed that the pathogenesis of UC is related to autoimmunity, infection, heredity, mental and environmental factors. At present, no specific treatment drugs and methods hav...

Claims

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