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112 results about "Immuno detection" patented technology
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Hybridoma cell strain secreting cy3.5 monoclonal antibody and application thereof
This invention relates to a hybridoma cell line that secretes a Cy3.5 monoclonal antibody and its application, belonging to the field of immunoassay. The hybridoma cell line of this invention was deposited on November 12, 2025, at the China General Microbiological Culture Collection Center (CGMCC), located at No. 3, Courtyard 1, Beichen West Road, Chaoyang District, Beijing, with accession number CGMCC No. 46741. The Cy3.5 monoclonal antibody secreted by this cell line exhibits excellent affinity and sensitivity to Cy3.5, with an IC50 of [missing value]. 50 Reaching 10 ng / mL, the IC50 for Cy5.5 50 An immunoassay product based on this hybridoma cell line, with a concentration of up to 50 ng / mL, can be used for the detection of Cy3.5 and its analogues, providing an efficient detection method and means for the residual detection of Cy3.5.
Owner:JIANGNAN UNIV
Long-persistent compounds, systems, and methods of preparation and use based on covalent bonding
This invention provides a long-afterglow compound, system, preparation method, and application based on covalent bond coupling. The long-afterglow compound absorbs photons and transfers the absorbed photon energy within the molecule, undergoing a photochemical reaction that releases the energy as light, thus achieving afterglow luminescence. The structure of the long-afterglow compound is shown in Formula I, where X is selected from O or S; R is selected from a photosensitizer; and n is 1–15. The long-afterglow system includes a carrier medium and a long-afterglow compound, wherein the carrier medium is used to dissolve, disperse, or adsorb the long-afterglow compound. This invention can achieve near-infrared luminescence at 660 nm and 718 nm, and can be applied in fields such as bioimaging, immune detection, cell tracking, biosensing, and information encryption.
Owner:SHANGHAI JIAOTONG UNIV
Hybridoma cell strain secreting monoclone antibody of pentachlorophenol and its application
This invention relates to a hybridoma cell line secreting a monoclonal antibody against pendimethalin and its application, belonging to the field of immunoassay. The hybridoma cell line secreting the pendimethalin monoclonal antibody of this invention was deposited on November 12, 2025, at the China General Microbiological Culture Collection Center (CGMCC), located at No. 3, Courtyard 1, Beichen West Road, Chaoyang District, Beijing, with accession number CGMCC No. 46744. The pendimethalin monoclonal antibody secreted by this hybridoma cell line is used for the analysis and detection of pendimethalin residues in food safety testing. The pendimethalin monoclonal antibody cell line obtained by this invention can be used for immunoassay detection, exhibiting good detection sensitivity and specificity (IC50) for pendimethalin. 50 The value was 1.87 ng / mL.
Owner:JIANGNAN UNIV
A specific detection method for *Daphnia magna* in nearshore marine aquatic ecosystem assessment
PendingCN122080161ARapid Field ScreeningImprove efficiencySerum immunoglobulinsImmunoglobulins against animals/humansAquatic ecosystemDaphnia sp.
This invention provides a specific detection method for *Daphnia magna* in nearshore marine aquatic ecosystem assessment. Based on obtaining the species-specific antigenic protein and key immunogenic peptides of *Daphnia magna*, a highly specific monoclonal antibody was successfully prepared and purified, and a colloidal gold side-flow chromatography rapid detection test strip was prepared using this antibody. The amino acid sequence of the antigenic protein is SEQ ID NO:1 or SEQ ID NO:2. This invention, by screening for the *Daphnia magna* species-specific antigen and its corresponding monoclonal antibody, combined with paired antibodies prepared from the full-length protein, and using them to develop a colloidal gold rapid immunoassay product, achieves for the first time high-throughput, rapid on-site screening of this species, significantly improving the efficiency and accuracy of marine ecological monitoring, ship ballast organism inspection, and aquaculture environmental assessment.
Owner:MARINE ENVIRONMENT MONITORING CENT STATION OF GUANGXI ZHUANG AUTONOMOUS REGION
Anti-shaking fluorescent immunochromatographic kit
This utility model relates to the field of immunoassay technology and discloses a shake-resistant fluorescent immunochromatographic reagent kit, including a placement box and a detection box. The detection box contains a test strip, a sample pad, and an absorption pad. The top of the detection box has a sample dispensing port and a display area. A support base is installed at the center of the top of the placement box, and a limiting seat is installed at the inner edge of the placement box. Both the top of the support base and the limiting seat have six sets of limiting grooves. This shake-resistant fluorescent immunochromatographic reagent kit can be stably placed using the placement box, and the test reagent can be tightly embedded in the limiting grooves for fixation. When adding the fluorescent immunochromatographic solution, excess liquid can fall into the placement box for collection and prevent leakage. The anti-slip pad at the bottom of the placement box improves stability, and the detection box embedded inside prevents shaking, thus achieving stable detection and solving the problem of poor stability.
Owner:ZHENGZHOU DONGGE BIOENGINEERING TECH RES INST CO LTD
A constant temperature shaking incubator for immunoassay kits and a method for adjusting the shaking frequency thereof
The present application relates to a kind of constant temperature shaking incubator for immunodetection kit and its shaking frequency adjusting method, belong to immunological analysis equipment technical field, including box, constant temperature module, shaking platform, drive mechanism and control system, still include: online temperature detection unit, set in the inside of box, for real-time acquisition kit current temperature signal;And optical detection unit, set in the above of shaking platform, for real-time monitoring the turbidity or light transmittance change of reaction liquid in kit, target temperature-time curve and target turbidity-time curve are built in control system, for receiving the feedback signal of online temperature detection unit and optical detection unit.In the present application, it solves the problem that traditional incubation equipment cannot dynamically adjust the shaking frequency according to the reaction process, leading to low reaction efficiency and large batch difference, significantly improves the sensitivity, specificity and result consistency of immunodetection.
Owner:盐城市第三人民医院
Method and system for detecting the strongest rayleigh acoustic streaming in a pinned microdroplet
This invention discloses a method and system for detecting the strongest Rayleigh acoustic current in immobilized microdroplets. Specifically, it involves: calculating the acoustic current suppression coefficient through experimental quantitative testing to establish a quantitative mapping relationship between acoustic current intensity and droplet contact angle; utilizing an electrowetting structure composed of interdigitated electrodes, a dielectric layer, and a hydrophobic layer to actively regulate the droplet contact angle through an applied voltage; and dynamically adjusting the applied voltage in real time by monitoring the droplet vibration amplitude, particle velocity, and contact angle through a collaborative control program to maintain the acoustic current intensity at its strongest. This invention also provides a detection system for implementing the above method, including an indium tin oxide transparent interdigitated electrode substrate, a lead zirconate titanate piezoelectric transducer, a laser Doppler vibrometer, a microscope, and a collaborative control module. This invention can maximize and dynamically maintain the Rayleigh acoustic current intensity in immobilized microdroplets, significantly accelerating the solid-liquid interface mass transfer process, and is applicable to biochemical analysis fields such as rapid immunoassay and biological particle mixing.
Owner:NANJING UNIV OF SCI & TECH
A mixing device for chemiluminescence immunoassay
The utility model belongs to chemical detection technical field especially for a kind of mixing device for chemiluminescence immunoassay, including mechanical arm, the lateral slide of mechanical arm is equipped with transverse drive arm, the side of transverse drive arm is equipped with longitudinal drive arm. This kind of mixing device for chemiluminescence immunoassay, by sliding connecting block on integrated plate vertical sliding drive gripper assembly vertical movement, sample and reagent are added into reaction cup, after reaction cup is grabbed by gripper assembly, vibration motor starts, drives vibration mounting seat and reaction cup vibration, rubber seat mainly provides a flexible connection, when gripper assembly vibration, it can provide a larger vibration amplitude to reach the mixing effect of sample and reagent in reaction cup. Such design, by the integration of gripper assembly and vibration motor, complete mixing action in the scheduling process of reaction cup, can simplify work flow, simultaneously, independent mixing mechanism is saved, and cost is saved.
Owner:SHENZHEN KECHUANG ZHIDA TECH CO LTD
Anti-TPO antibodies or antigen-binding fragments thereof
ActiveCN122080220Ahigh affinityImprove stabilityImmunoglobulins against enzymesMaterial analysisAntiendomysial antibodiesAntigen Binding Fragment
The invention relates to the technical field of immunodetection, in particular to an anti-TPO antibody or an antigen binding fragment thereof. The anti-TPO antibody provided by the invention has the characteristics of high affinity and good stability, and provides a raw material source with excellent performance for the preparation of a calibration product / a positive control product / a quality control product of a TPO antibody detection kit.
Owner:SHENZHEN NEW INDS BIOMEDICAL ENG CO LTD +1
Metomidine haptens and complete antigens, and methods of making and using the same
This invention relates to a medemididine hapten, a complete antigen, and their preparation methods and applications. The structure of the medemididine hapten is shown in Formula I. The preparation method of the medemididine hapten includes: (1) substituting medemididine with ethyl 3-bromopropionate to obtain intermediate 2; (2) adding sodium hydroxide to deprotect the ester group to obtain medemididine hapten 3. The structure of the complete antigen is shown in Formula II. The preparation method of the complete antigen includes: coupling the medemididine hapten with a carrier protein to obtain the complete antigen. This invention discloses a method for preparing medemididine hapten and complete antigen. The synthesis steps are simple and effective, and it can be used in immunoassay. Among them, colloidal gold immunochromatography is simple to operate, has a short detection time, high specificity, and good reproducibility, which can meet the domestic demand for immunoassay of medemididine.
Owner:JIANGSU VOCATIONAL COLLEGE OF MEDICINE
Anti-ccrp antibodies or functional fragments thereof and uses thereof
The present application relates to the field of biotechnology, in particular to anti-cCRP antibody or its functional fragment and application thereof. The present application not only provides a kind of monoclonal antibody (wild type) with high affinity to cCRP, but also carries out site-directed mutagenesis to the wild type, and verifies the affinity of each mutation, which provides a reference for the research in the field of immune detection of cCRP.
Owner:CHONGQING ESSENCE BIOENGINEERING CO LTD
Hybridoma cell strain secreting monoclonal antibody of chlorinated nitrogen aminophenazone and its application
The present application relates to a hybridoma cell strain secreting a chlorinated nitrogen aminophenazone monoclonal antibody and its application, and belongs to the technical field of immune detection. The hybridoma cell strain secreting a chlorinated nitrogen aminophenazone monoclonal antibody was preserved in the China General Microbiological Culture Collection Center on April 24, 2026, and the address of the preservation is No. 1, Beichen West Road, Chaoyang District, Beijing, and the preservation number is CGMCC No. 46821. The monoclonal antibody secreted by the hybridoma cell strain of the present application has good detection sensitivity (IC 50 Value is 0.27 ng / mL) to chlorinated nitrogen aminophenazone, and can be used for the residual detection of chlorinated nitrogen aminophenazone.
Owner:JIANGNAN UNIV
A mycophenolic acid chemiluminescence immunoassay reagent and its preparation and detection method
PendingCN122361803AStrong immunogen specificityStrong specificityAntiendomysial antibodiesMycophenolic acid
The present application relates to a kind of mycophenolic acid detection reagent and its preparation and detection method, specifically a kind of mycophenolic acid chemiluminescence immunoassay reagent and its preparation and detection method, comprising: anti mycophenolic acid specific antibody, for detecting the indicating reagent of anti mycophenolic acid specific antibody-mycophenolic acid combination;The above anti mycophenolic acid specific antibody is obtained by mycophenolic acid immunogen immunization animal.The present application has the advantages that: the mycophenolic acid immunogen of the present application is specific, and immunogenicity is high, and the prepared anti mycophenolic acid specific antibody is specific, and titer is high;Chemiluminescence immunoassay reagent containing the above anti mycophenolic acid specific antibody can determine the mycophenolic acid content in sample conveniently, quickly and accurately, and multiple samples can be simultaneously determined on full-automatic chemiluminescence immunoassay analyzer, realize the high-throughput rapid determination of mycophenolic acid, and the accuracy is high, and the specificity is strong, and accuracy and detection efficiency have been greatly improved.
Owner:SUZHOU EVERMED BIOMEDICAL CO LTD
A single-cell microarray-based reagent kit and method for in situ quantitative detection of receptor-binding allergen-specific IgE.
This invention discloses a single-cell microarray-based kit and method for in situ quantitative detection of receptor-binding allergen-specific IgE. The kit includes: a single-cell microcavity array chip, an antigen barcode chip, a plastic clamp, IgE standards, fluorescently modified IgE detection antibodies, and auxiliary reagents. During detection, basophil single cells are loaded into the microcavity array chip, lysis buffer is added, and the cells are clamped together with the antigen barcode chip. Low-temperature incubation allows the allergen-specific IgE released from cell lysis to be captured in situ by the antigen on the chip. A sandwich immunoassay is then performed using a fluorescently labeled antibody, and absolute quantification is achieved using a standard curve. This invention is the first to achieve high-throughput, high-sensitivity, multi-component parallel in situ quantitative detection of basophil membrane receptor-binding sIgE at the single-cell level. It can directly reflect the functional sensitization state of effector cells and has advantages such as simple operation, low sample requirement, and no need for complex valve devices.
Owner:SHANDONG UNIV
Application of trifluoromethanesulfonyl magnetic nanospheres in chemiluminescence immunoassay
This invention provides the application of trifluoromethanesulfonyl magnetic nanospheres in chemiluminescent immunoassay. The trifluoromethanesulfonyl magnetic nanospheres are used for direct covalent coupling with antigens or antibodies. The specific preparation method includes first forming epoxy magnetic nanobead micelles, then adding trifluoromethanesulfonyl chloride as a modifier in batches under conditions of 0-25°C to obtain a crude product of trifluoromethanesulfonyl magnetic nanospheres. Then, the particles are screened by column chromatography and centrifugation to obtain the final product of trifluoromethanesulfonyl magnetic nanospheres. The trifluoromethanesulfonyl magnetic nanospheres have stronger thermal stability than p-toluenesulfonyl magnetic nanobeads, eliminating the need for an activation step. Under the action of ammonium sulfate catalyst, they are directly covalently coupled with amino-containing biomacromolecules, reducing antibody cross-linking and magnetic bead aggregation caused by activators such as EDC or glutaraldehyde.
Owner:GETEIN BIOTECH
An aldosterone sandwich method antibody mAb5 or antigen-binding fragment thereof, and a preparation method and application thereof
PendingCN122130965AChemiluminescene/bioluminescenceBiological testingDiseaseComplementarity determining region
This application belongs to the field of immunoassay technology, and discloses an aldosterone sandwich antibody mAb5 or its antigen-binding fragment, its preparation method, and its applications. The aldosterone sandwich antibody mAb5 or its antigen-binding fragment includes a light chain variable region (VL) and a heavy chain variable region (VH). The light chain variable region (VL) includes complementarity-determining regions (LCDR1, LCDR2, and LCDR3), whose amino acid sequences are shown in SEQ ID NO. 1-3, respectively. The heavy chain variable region (VH) includes complementarity-determining regions (HCDR1, HCDR2, and HCDR3), whose amino acid sequences are shown in SEQ ID NO. 4-6, respectively. Using the aldosterone sandwich antibody mAb5 of this application to detect aldosterone standard antigens, the detection sensitivity is less than 7 pg / mL. Magnetochemiluminescence immunoassay of clinical samples shows good correlation with clinical results within the sample range of 0-1000 pg / mL, which is of great significance in the diagnosis and treatment of essential hypertension and other aldosterone-related diseases.
Owner:ORIGENE WUXI BIOTECHNOLOGY CO LTD
Hybridoma cell strain secreting monoclonal antibody of anti-imitac and its application
Owner:JIANGNAN UNIV
A hybridoma cell line secreting basic yellow O monoclonal antibody and its application
This invention relates to a hybridoma cell line that secretes a monoclonal antibody against Basic Yellow O and its application, belonging to the field of immunoassay. The hybridoma cell line of this invention was deposited on November 12, 2025, at the China General Microbiological Culture Collection Center (CGMCC), located at No. 3, Courtyard 1, Beichen West Road, Chaoyang District, Beijing, with accession number CGMCC No. 46740. This invention obtains the Basic Yellow O hapten through multiple screenings and experiments, then prepares the Basic Yellow O complete antigen from the hapten, and uses this complete antigen to immunize animals to obtain a hybridoma cell line. The Basic Yellow O monoclonal antibody secreted by this cell line exhibits excellent affinity and sensitivity to Basic Yellow O, with an IC50 value of [missing information - likely a value]. 50 With a concentration of 1 ng / mL, it can be used to prepare immunoassay products for Basic Yellow O, providing an efficient detection method and means for the detection of Basic Yellow O residues in food.
Owner:JIANGNAN UNIV
An ai-assisted result interpretation leishmania major infection micro-sample detection kit and antibody detection method
PendingCN122150574AAcquiring/recognising microscopic objectsAgainst vector-borne diseasesLeishmania majorMurine antibody
The application relates to an AI-assisted result interpretation micro-sample detection kit for cutaneous leishmaniasis infection and an antibody detection method, and belongs to the technical field of serological immunodetection. The kit comprises an antibody detection platform for micro-samples, micro-bead probes, a washing solution, an antibody diluent, F594-labeled sheep anti-rat antibodies, positive quality control serum and negative quality control serum; the spherical probes are adopted in the application, the antigen-antibody combination efficiency is improved in space, and the antigen-antibody collision probability is effectively improved. Meanwhile, the micro-beads form a micro-scale mass transfer network in the reaction cavity, fluid mixing is enhanced, the reaction time is shortened, and the overall residence time and consumption of samples and reagents in the microfluidic channel are reduced. The application also introduces an AI-assisted result interpretation system to assist in result interpretation, significantly improves the friendliness and accessibility of the detection process, the classification model based on artificial intelligence has stronger robustness and judgment consistency, and has good market development value and popularization and application prospect.
Owner:JILIN UNIVERSITY
Fusion proteins, conjugates containing same, kits and uses
The present disclosure provides a fusion protein, a conjugate containing the same, a kit and use, belonging to the technical field of immunodiagnosis. The fusion protein of the present disclosure comprises a protein tag and a protein part, the fusion protein containing the protein tag has improved activity or specificity, and the fusion protein is used for immunodetection, which can improve the sensitivity or specificity of immunodetection.
Owner:FAPON BIOTECH INC
A chemiluminescent immunoassay method
PendingCN122171790AChemiluminescene/bioluminescenceBiological testingDisulfide bondingSpecific adsorption
This invention discloses a chemiluminescent immunoassay method, comprising the following steps: labeling disulfide-bonded biotin or desulfobiotin onto affinity ligand one to form complex one; labeling a luminescent compound onto affinity ligand two to form complex two; mixing the sample with a solid-phase carrier containing complex one, complex two, and streptavidin-coupled compound to form an immunosandwich complex; processing the immunosandwich complex to release the immunosandwich complex from the solid-phase carrier; separating the immunosandwich complex from the solid-phase carrier; detecting the total luminescent signal value of the separated immunosandwich complex; and calculating the concentration of the analyte based on the total luminescent signal value. This invention releases the immunosandwich complex from the solid-phase carrier, uses a magnetic field to attract the solid-phase carrier, and measures the supernatant of the released immunosandwich complex. Solid-phase carriers containing non-specific adsorption cannot enter the measurement chamber, completely eliminating the problem of non-specific adsorption on the surface of magnetic beads.
Owner:GETEIN BIOTECH
An image recognition-based superfine high-fiber instant broccoli pollen particle size monitoring method
This invention discloses a method for monitoring the particle size of ultrafine, high-fiber, fast-dissolving broccoli pollen based on image recognition, belonging to the field of immunoassay system technology. The method includes: constructing an image acquisition system; selecting an appropriate imaging module and shooting parameters based on whether the sample is broccoli pollen paste or dried powder; acquiring microscopic images of the sample; preprocessing the acquired microscopic images by sequentially performing image denoising, grayscale conversion, binarization, and edge enhancement to eliminate recognition errors caused by background interference and particle adhesion; using a contour extraction algorithm to identify particle contours in the preprocessed images, combining area, roundness, and pixel thresholds for feature filtering to remove impurities and pseudo-particle contours, obtaining a dataset of valid broccoli pollen particle contours; this invention achieves simultaneous analysis of particle size, particle size distribution range, and specific surface area, without requiring additional detection equipment, and can output multiple indicators directly related to broccoli pollen quality and process optimization from a single image acquisition.
Owner:JINAN INST OF FRUIT PRODS CHINA GENERAL SUPPLY & MARKETING COOP
A hybridoma cell line that secretes monoclonal antibodies against BHT and its analogues
This invention relates to a hybridoma cell line that secretes monoclonal antibodies against BHT and its analogues, belonging to the field of immunoassay technology. The monoclonal antibodies secreted by the hybridoma cell line of this invention exhibit good sensitivity to BHT and its analogues. The monoclonal antibodies of this invention can simultaneously detect BHT, BHA, and TBHQ, and have an IC50 value for BHT. 50 The concentration was 83.08 ng / mL, and the IC50 for BHA was... 50 The concentration was 92.2 ng / mL, and the IC50 for TBHQ was [missing value]. 50 With a concentration of 86.0 ng / mL, the monoclonal antibody of this invention can simultaneously detect trace amounts of BHT, BHA, and TBHQ, and can be used for the residual detection of BHT, BHA, and TBHQ.
Owner:JIANGNAN UNIV
Products for early diagnosis of sepsis and use thereof
The present application relates to the field of immunoassay technology, discloses a product for early diagnosis of sepsis and its application, the composition of the product for early diagnosis of sepsis includes detecting SAA1 protein and PDL1 + The product for detecting the content of exosome in sample is based on antigen-antibody specific immune binding to detect SAA1 protein and PDL1 + The product for detecting the content of exosome in sample, the detection method adopted by the detection product is selected from one of fluorescence immunoassay, enzyme-linked immunosorbent assay, colloidal gold immunochromatography, chemiluminescence immunoassay, electrochemical immunoassay and nanopore-based immunosensing detection method, the product for early diagnosis of sepsis improves the accuracy of early diagnosis of sepsis and disease condition evaluation in a double-index cooperative manner, effectively solves the technical bottleneck that the existing sepsis detection method is insufficient in sensitivity, poor in specificity and difficult to meet the requirements of early precise diagnosis and dynamic disease condition evaluation.
Owner:GUANGDONG HOSPITAL OF TRADITIONAL CHINESE MEDICINE
An adaptive signal-to-noise ratio enhancement algorithm based on a multi-modal immunodetection system
The application discloses a kind of adaptive signal-to-noise ratio enhancement algorithms based on multi-modal immune detection system, it is related to immune detection system technical field, including, image signal module, spectral signal module, time dynamics module, noise profile generator, cross-modal attention fusion module, SNR Boost Kernel signal-to-noise ratio promotion kernel, and with the enhancement index output module GBE connected to SNR Boost Kernel;Each module cooperates, and the signal-to-noise ratio of multi-modal signal is uniformly enhanced by cross-modal consistency constraint, the multi-modal signal includes camera image signal, visible spectrum signal, near-infrared spectrum signal and time dynamics curve signal, the present application realizes the collaborative denoising of multi-modal signal and signal-to-noise ratio uniform enhancement, improves the overall performance of multi-modal immune detection platform, realizes seamless link with parent case processing link.
Owner:SHANGHAI GUANLU MEDICAL EQUIPMENT TECHNOLOGY CO LTD
Antibodies or antigen-binding fragments that bind to thyroglobulin
PendingCN122080202Ahigh affinityImmunoglobulins against animals/humansBiological testingAntigenAntigen Binding Fragment
This invention relates to the field of immunoassay technology, and more specifically, to an antibody or antigen-binding fragment thereof capable of binding to thyroglobulin. The antibody or antigen-binding fragment thereof provided by this invention exhibits excellent affinity and sensitivity for thyroglobulin.
Owner:SHENZHEN LONGGANG DISTRICT PEOPLES HOSPITAL
A hepcidin chemiluminescence immunoassay kit and a non-diagnostic method for detecting hepcidin
PendingCN122150567AChemiluminescene/bioluminescenceBiological testingAntiendomysial antibodiesActive agent
The application relates to a hepcidin chemiluminescence immunoassay kit and a non-diagnostic method for detecting hepcidin, the kit comprising a calibrator, a quality control, an integrated bifunctional antibody reagent, a magnetic particle reagent, a cleaning solution and a chemiluminescence substrate solution; the integrated bifunctional antibody reagent is a buffer containing HEP-specific antibodies covalently connected with fluorescein isothiocyanate and alkaline phosphatase through pH-sensitive connecting bonds; the magnetic particle reagent is a magnetic microsphere suspension coated with a goat anti-fluorescein isothiocyanate antibody; the cleaning solution is a buffer containing a surfactant composition, and the surfactant composition comprises nonionic surfactants, zwitterionic surfactants and high-molecular nonionic surfactants. The hepcidin chemiluminescence immunoassay kit has the effects of ultra-low background noise, ultra-high sensitivity, ultra-wide linear range and simplified operation of end users by means of the integrated bifunctional antibody reagent and the surfactant composition cleaning solution.
Owner:HENAN YIRUI BIOTECHNOLOGY CO LTD
Hybridoma cell strain secreting monoclone antibody of bensulfuron methyl and its application
The present application relates to a hybridoma cell strain secreting a dimethomorph monoclonal antibody and its application, and belongs to the field of food safety immune detection. The hybridoma cell strain DBL secreting a dimethomorph monoclonal antibody has been preserved in the China General Microbiological Culture Collection Center on April 17, 2025, with a preservation number of CGMCC No. 46510, a preservation address of No. 3, Beichen West Road, Chaoyang District, Beijing, and a classification designation of a monoclonal cell strain. The dimethomorph monoclonal antibody obtained by using the strain to secrete can be used for the analysis and detection of dimethomorph residues in food safety detection. The dimethomorph monoclonal antibody cell strain obtained by the present application can be used for immune analysis and detection, and has good detection sensitivity (IC 50 value of 104.49 ng / mL) for dimethomorph.
Owner:JIANGNAN UNIV
Use of proteolytic enzymes to reduce or eliminate interfering antibodies in immunoassays
The present application provides the use of proteolytic enzymes to reduce or eliminate interfering antibodies in immunoassays for antigens and / or antibodies. The present disclosure utilizes biological methods or biological methods in combination with chemical methods to disrupt the structure of interfering antibodies, thereby attenuating or even eliminating the signal (false positive) or masked signal (false negative) from interfering antibodies, which can significantly improve the accuracy of reagent detection.
Owner:CHEMCLIN DIAGNOSTICS CO LTD
An immunodetection device with sampling and immersion functions
Owner:THE FIRST AFFILIATED HOSPITAL OF ARMY MEDICAL UNIV