Apparatus and method for full-automatic simulation of human gastrointestinal tract digestion and enzymolysis

A fully automatic technology for digestion of the gastrointestinal tract, applied in biochemical cleaning devices, biochemical equipment and methods, enzymology/microbiology devices, etc., can solve the problem that there is no detailed simulation and description of the emptying process, and the description of parameters is not enough Detailed, simulating the specific digestion of the oral cavity without detailed explanations, etc.

Pending Publication Date: 2020-05-05
NANCHANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0006] These patent documents have greatly enriched the devices and methods of use suitable for digestive fermentation, but so far, these patents have not detailed the simulation of oral cavity specific digestion; There is no detailed simulation and description of the process; at the same time, these patents are not detailed enough to control the parameters in the small intestine simulation system and large intestine fermentation system; some of these patents are only based on animal-related parameters and have little relevance to humans

Method used

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  • Apparatus and method for full-automatic simulation of human gastrointestinal tract digestion and enzymolysis
  • Apparatus and method for full-automatic simulation of human gastrointestinal tract digestion and enzymolysis
  • Apparatus and method for full-automatic simulation of human gastrointestinal tract digestion and enzymolysis

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Embodiment 1

[0067] This embodiment will introduce the fully automatic device for simulating digestion and fermentation of human gastrointestinal tract according to the present application with reference to the accompanying drawings.

[0068] A fully automatic device for simulating digestion and fermentation of the human gastrointestinal tract, which includes an equipment frame, an electrical control box for the equipment, and mouth digestion tanks installed in the equipment frame for simulating digestion and fermentation of the human gastrointestinal tract and connected in sequence , gastric digester, duodenal digester, jejunal digester, ileal digester, ascending colon digester, transverse colon digester and descending colon digester. Refer to the attached figure 1 , the digestion tanks are connected sequentially through transfer pipelines, and the jejunum digestion tank, ileum digestion tank, ascending colon digestion tank, and transverse colon digestion tank are connected with membrane ...

Embodiment 2

[0079] This embodiment will introduce in detail a fully automatic method for simulating digestion and fermentation of the human gastrointestinal tract of the present application.

[0080] The method is applied to the fully automatic device for simulating digestion and fermentation of the human gastrointestinal tract in Example 1, and the method specifically includes the following steps:

[0081] Step1: Connect the digestion tanks, supporting pipelines, supply pipelines and detection electrodes;

[0082] Step2: Disinfection of empty cans

[0083] Turn on the magnetic stirring of each digestion tank, enter the high-pressure pure water cleaning, and the residue is discharged from the drain valve 105 at the bottom of each digestion tank. Enter the steam to carry out high-temperature disinfection of each digestion tank, the disinfection time is 25-30min, after the end, inject nitrogen, then enter 80-100mL ethanol to each transfer peristaltic pump pipeline and sampling pipeline for...

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Abstract

The invention discloses an apparatus and method for full-automatic simulation of human gastrointestinal tract digestion and enzymolysis. The apparatus comprises an equipment frame, an equipment electrical control box, and an oral digestion tank, a stomach digestion tank, a duodenum digestion tank, a jejunum digestion tank, an ileum digestion tank, an ascending colon digestion tank, a transverse colon digestion tank and a descending colon digestion tank which are installed in the equipment frame, used for simulating the human gastrointestinal tract digestion and enzymolysis, and sequentially connected. The apparatus and method for full-automatic simulation of all components of the human gastrointestinal tract are explained in detail for the first time, and the detailed simulation description of the structure and design of each part is performed for the first time. The apparatus and the implementation method thereof can realize observation of digestion and enzymolysis of various foods, active or nutrient substances after entering the human body, and help to explore digestion and enzymolysis of various foods, active or nutrient substances after entering the human body.

Description

technical field [0001] The invention belongs to the technical fields of bionics, human physiology, microbiology, nutrition, organic chemistry and analysis and testing. To be precise, it relates to a device and method for fully automatic simulating digestion and fermentation of human gastrointestinal tract. Background technique [0002] The human body's digestion and absorption of food is a very complicated process. After food is ingested, it is converted into nutrients for the body to grow. During human digestion, two major processes occur almost simultaneously: (1) the particle size of food is reduced during mechanical transport in the digestive tract; (2) large molecules in food are hydrolyzed into smaller molecules and then absorbed into the blood. Food pulverization mainly occurs in the mouth and stomach, while enzymatic hydrolysis and absorption of nutrients and water mainly occur in the small and large intestines. [0003] Currently, the digestive system is the focus ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M1/36C12M1/00G01N33/02G09B23/28
CPCC12M23/58C12M41/48G01N33/02G09B23/28
Inventor 聂少平胡婕伦嵇海华张珊珊聂启兴谢明勇
Owner NANCHANG UNIV
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