FFR rapid calculation system model based on zero-dimensional hemodynamic model

Abstract

The invention discloses an FFR rapid calculation system model based on a zero-dimensional hemodynamic model, which belongs to the field of hemodynamic numerical simulation. The system comprises a personalized zero-dimensional hemodynamic construction model, a stenosis resistance theoretical calculation model, a stenosis resistance determination model and an FFR model. In a resting state, the zero-dimensional model is personalized through coronary artery post-load and other model parameters including the heart. In a hyperemia state, the stenosis resistance output by the resistance model is taken as the input of the zero-dimensional model to influence the flow distribution of each branch of the coronary artery of the zero-dimensional model, and the stenosis branch flow output by the zero-dimensional model is taken as the input of the resistance model to recalculate the stenosis resistance. The two models are repeatedly iterated until the flow is matched with the resistance, the stenosisresistance is finally determined, the pressure of each branch of the coronary artery is obtained, and the FFR is calculated according to the ratio of the average pressure of the distal stenosis end tothe average pressure of the root of the aorta in the hyperemia state. The system can quickly and accurately calculate the FFR. The system is rapid and accurate.

Description

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AI Technical Summary

Benefits of technology

This patented technology allows quick calculations by creating an accurate mathematical description of blood flow through arteries with specific characteristics such as pressure or velocity changes caused due to various factors like heart activity (cardiovascular disease) or other conditions associated therewith. By doing this, researchers can study how these properties affect blood circulation and potentially improve diagnoses related therapies.

Problems solved by technology

This patents discuss how different methods exist for accurately measuring the degree or severity of blockages caused by plaque deposits within the vasculature of patients who require medical treatment. These existing measures involve imaging procedures like angioangiectomy and fluorescence dye injection. While some newer technologies use Computed Tomography ("CT"), there may also be other options available but they still suffer from limitations including complexity, costly calculations, slowness, etc., which make them difficult to implement in practice.

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