52 results about "Bioprosthetic mitral valve replacement" patented technology

Apparatus is described for use with a native heart valve of a subject, the apparatus including (1) a prosthetic valve support, comprising an upstream support portion, the upstream support portion having (a) a compressed configuration and an uncompressed configuration in which the upstream support portion has an inner perimeter that defines an opening; and (2) a prosthetic valve, advanceable into the opening defined by the upstream support portion, and intracorporeally couplable to the upstream support portion by being expanded within the opening defined by the upstream support portion, the apparatus being configured such that, when the prosthetic valve is expanded within the opening defined by the upstream support portion, the expansion of the prosthetic valve is restricted by the inner perimeter of the upstream support portion, without causing the prosthetic valve support to apply a radially-expansive force to the native annulus. Other embodiments are also described.

A mitral valve replacement device is adapted to be deployed at a mitral valve position in a human heart. The device has an atrial flange defining an atrial end of the device, a valve body defining a ventricular end of the device, and an annulus support that connects the atrial flange and the valve body, the annulus support including a ring of tabs extending radially therefrom and adapted to engage the native mitral annulus and/or the native leaflet(s) of the human heart. The atrial flange can be seated in the atrium above the native mitral valve annulus in a human heart, and the ring of tabs can engage the native mitral annulus in a manner where the atrial flange and tabs provide a clipping effect to secure the mitral valve replacement device at the native mitral valve position

This invention relates to a delivery apparatus and method for deployment of a mitral valve replacement.

A prosthetic heart valve includes a collapsible and expandable stent having an outflow end and an inflow end, a plurality of commissure features attached to the stent, a plurality of anchoring features disposed on legs of the stent, the plurality of anchoring features being coupleable to a delivery device for repositioning, and a valve assembly disposed within the stent. The anchoring features may be configured to attach to heart tissue to help secure the prosthetic heart valve in an operating position.

Apparatus for use at a native heart valve of a subject is described. For some applications, the apparatus comprises a prosthetic valve support, configured (a) to be implanted at the native valve, (b) to facilitate, at a first period, implantation at the native valve of a first prosthetic valve, and (c) to facilitate, at a second period, implantation at the native valve of a second prosthetic valve. Other embodiments are also described.

Transcatheter mitral valve replacement is provided which includes a stabilizing stent portion for placement at a mitral annulus, with a narrowed waist portion to avoid significantly dilating the annulus, and expanded bulb portions at the atrial and ventricular ends to secure the device in position. A housing is attached to the stabilizing stent and reduces in diameter to a smaller tract portion where replacement valve leaflets are secured. The resulting smaller replacement mitral valve offers benefits including a lower introduction profile, yet fits and secures to the native annulus by the securing stent and housing. Expansion limiting elements can limit expansion of portions of self-expanding stent if desired, avoiding excessive mitral annulus dilation or providing a fixed diameter in other portions of the stent or housing. Two-step implantation can be accomplished by making the housing functional as a temporary valve.

A mitral valve replacement device is adapted to be deployed at a mitral valve position in a human heart. The device has an atrial flange defining an atrial end of the device, a ventricular portion defining a ventricular end of the device, the ventricular portion having a height ranging between 2 mm to 15 mm, and an annulus support that is positioned between the atrial flange and the ventricular portion. The annulus support includes a ring of anchors extending radially therefrom, with an annular clipping space defined between the atrial flange and the ring of anchors. A plurality of leaflet holders positioned at the atrial end of the atrial flange, and a plurality of valve leaflets secured to the leaflet holders, and positioned inside the atrial flange at a location above the native annulus.

A prosthetic device for use in an anatomical orifice or lumen of a patient includes an expandable first stent structure coupled to a valve support structure having at least one leaflet. The stent structure includes a collar provided with at least one groove or opening adapted to engage a tab extending from the valve support structure. Rotation of the stent structure and valve support structure relative to one another assembles the prosthetic valve device. The prosthetic valve device may be used for sutureless treatment of various valvular conditions such as aorta stenosis and mitral valve replacement.

Methods related to delivery of various heart valve implants are described. The implant may be delivered using an ultrasound imaging delivery system. The ultrasound imaging delivery system may be used to deliver a variety of different devices, including mitral valve reshaping devices, mitral valve replacement valves, and others. A deployment catheter carrying an implant having a tissue anchor is advanced to a deployment site in a heart. An imaging element is positioned adjacent the implant and a relationship between the tissue anchor and an anatomical landmark in the heart is visualized. The implant is then attached by driving the tissue anchor into tissue in the heart.

The invention relates to a mitral valve replacement system for a percutaneous transcatheter, and belongs to the technical field of medical instruments. The mitral valve replacement system comprises avalve frame supporting body, an artificial valve leaflet and a ventricular septum anchoring structure. The valve frame supporting body is arranged between an atrium and a ventricle and provided with ahollow cavity with the two ends open. The artificial valve leaflet is arranged on the inner wall of the cavity of the valve frame supporting body. The ventricular septum anchoring structure is arranged between the valve frame supporting body and a ventricular septum. The invention provides the mitral valve replacement device intervened through a catheter via a femoral vein admission passage and aims to solve the problems that an existing interventional mitral valve system is generally large in valve stent, has the left ventricular outflow passage obstruction risk, has potential complicationsin transapical admission passage and anchoring and the like, and the mitral valve replacement device provided by the invention is more minimally invasive and firmer in anchoring, and the technical scheme of mitral valve replacement suffering from left ventricular outflow tract obstruction can be effectively avoided.

In one representative embodiment, a prosthetic valve assembly for replacing a native heart valve comprises a radially expandable and compressible support structure, the support structure comprising anannular frame having a lumen extending from an inflow end to an outflow end, the support structure further comprising an annular sealing member extending radially inwardly into the lumen of the frameand having an inner peripheral portion defining an orifice, and a radially expandable and compressible valve component, the valve component comprising an annular frame and a valve structure supportedinside of the frame for permitting the flow blood through the valve component in one direction and blocking the flow of blood in the opposite direction, wherein the valve component is configured to expand within the orifice of the sealing member and engage the inner peripheral portion of the sealing member when radially expanded.

A mitral valve replacement device is adapted to be deployed at a mitral valve position in a human heart. The device has an atrial flange defining an atrial end of the device, a ventricular portion defining a ventricular end of the device, the ventricular portion having a height ranging between 2 mm to 15 mm, and an annulus support that is positioned between the atrial flange and the ventricular portion. The annulus support includes a ring of anchors extending radially therefrom, with an annular clipping space defined between the atrial flange and the ring of anchors. A plurality of leaflet holders positioned at the atrial end of the atrial flange, and a plurality of valve leaflets secured to the leaflet holders, and positioned inside the atrial flange at a location above the native annulus.

The invention relates to the field of medical instruments, in particular to a heart valve prosthesis capable of being anchored with autologous valve leaflets. The heart valve prosthesis comprises: a valve stent with a preset form; a clamping mechanism which has a preset form, wherein the near end of the clamping mechanism is connected with the valve stent, and at least part of the clamping mechanism is attached to the outer side of the valve stent; and an anchoring ring which is connected with the far end of the clamping mechanism in a matched mode, wherein when the clamping mechanism is released, the clamping mechanism is located on the periphery of the autologous valve leaflet, the anchoring ring surrounds the autologous valve leaflet, and when the valve stent is released, the clamping mechanism is attached to the valve stent, and the valve stent supports the anchoring ring in the radial direction. In addition, the anchoring ring in the scheme can curl part of the autologous valve leaflet, the influence of original valve leaflet tissue on blood flow after replacement is reduced, the two technical pain points about mitral valve replacement therapy in the prior art are solved, and good clinical significance is achieved.

The invention provides a split valve stent and an interventional mitral valve replacement system comprising the same. The split valve stent comprises an outer frame and an inner frame arranged in the outer frame and matched with the outer frame; the outer frame comprises a cylindrical outer metal frame with a kidney-shaped section, one end of the outer metal frame is folded outwards in the circumferential direction to form a supporting ring, and at least one hook is arranged at the kidney-shaped concave position of the other end of the outer metal frame; the inner frame comprises a cylindrical inner metal frame with a kidney-shaped section, two connecting wires which are crossed in an X shape are arranged at one end of the inner metal frame, and the interface of the end of the inner metal frame is cut into an 8 shape by the two connecting wires; and when the outer frame is in the unfolded state, the side, provided with the supporting ring, of the outer frame is reversely buckled to a valve ring on one side of the left atrium, the side, provided with the hook, of the outer frame extends into the left ventricle, and when the inner frame is in the unfolded state, the side, not provided with the connecting wire, of the inner frame faces the left atrium, and the side, provided with the connecting wire, of the inner frame extends into the left ventricle.

The invention belongs to the technical field of medical instruments, and particularly relates to a mitral valve replacement device and a using method thereof. The mitral valve replacement device comprises a stent used for supporting an artificial valve leaflet and an anchoring part used for anchoring the artificial valve leaflet to an original valve leaflet, the stent is connected with a suture film through a suture line, the stent is of a D-shaped structure, and the stent is fitted with the original valve; the artificial valve leaflet is fixedly connected with the stent, and the anchoring part is used for attaching the artificial valve leaflet to the original valve leaflet; the artificial valve leaflet device with the stent is conveyed to the position of the original valve through a conveying device, and reflux caused by incomplete closing and calcification of the valve is effectively avoided; and the device can also be used for replacing the original valve, has the effect of ventricular volume reduction, improves the heart function and has important clinical significance.

The invention mainly aims to provide a surgery aid which is applied to aortic valve replacement and mitral valve replacement and convenient for suturing artificial valves with the heart valve ring in an equal stitch length and uniform distribution manner, and relates to a drape used in cardiac surgery. The drape is characterized by comprising a heart drape body (24), and a round opening (23) is formed in the center of the heart drape body (24). The drape is characterized by further comprising a multifunctional ring (1) fixed outside the round opening (23), at least two mark points on the multifunctional ring can be used for quadrant partition, and the multifunctional ring has a surgery wire clamping function. By application of the mark type heart drape, occurrence of complications of perivalvular leakage and the like can be lowered greatly, the surgery time is shortened, the use time of all monitoring devices is shortened as well, and the medical cost of patients is lowered correspondingly.