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336results about "Lens cleaning compositions" patented technology
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Ophthalmic Solutions
InactiveUS20080314767A1Avoid pollutionLens cleaning compositionsPackage sterilisationOsmolar ConcentrationNon ionic
Disclosed are ophthalmic solutions such as packaging solutions for storing ophthalmic devices and lens care solutions for cleaning, disinfecting, rinsing and / or storing ophthalmic devices. The ophthalmic solutions contain at least a polymerization product obtained from a monomeric mixture comprising (a) a monomer bearing a center of permanent positive charge and (b) a non-ionic ethylenically unsaturated monomer, wherein the solution has an osmolality of at least about 200 mOsm / kg, and a pH of about 4 to about 9.
Owner:BAUSCH & LOMB INC
Use of PEO-PBO block copolymers in ophthalmic compositions
The use of poly(oxyethylene)-poly(oxybutylene) block copolymers in pharmaceutical compositions useful for modifying the surfaces of contact lenses and other medical devices is disclosed. The present invention is based in-part on a discovery that this class of compounds is particularly efficient in wetting hydrophobic surfaces, such as the surfaces of silicone hydrogel contact lenses and other types of ophthalmic lenses. Such compounds are also useful for cleaning purposes. The use of the compounds as surfactants in various types of compositions for treating contact lenses therefore represents a preferred embodiment of the present invention.
Owner:ALCON INC
Antioxidants for post-cmp cleaning formulations
ActiveUS20090239777A1Maximum cleaningLens cleaning compositionsNon-surface-active detergent compositionsCopper interconnectAntioxidant
An cleaning composition and process for cleaning post-chemical mechanical polishing (CMP) residue and contaminants from a microelectronic device having said residue and contaminants thereon. The cleaning compositions include novel corrosion inhibitors. The composition achieves highly efficacious cleaning of the post-CMP residue and contaminant material from the surface of the microelectronic device without compromising the low-k dielectric material or the copper interconnect material.
Owner:ENTEGRIS INC
Contact lens solution
InactiveUS20050074467A1Safe for eyeSuppresses the adhesion of a large amount of polylysineSpectales/gogglesOrganic detergent compounding agentsPhosphoric acidNitrogen
A liquid formulation for contact lenses which comprises polylysine, polyphosphoric acid and / or salt thereof as a substance for suppressing the adhesion of polylysine to a contact lens, nitrogen-containing organic anti-microbial agent excluding polylysine and water. Contact lenses can be cleaned, disinfected and stored simply by soaking them in the liquid formulation without cleaning by digital rubbing or without rinsing before they are worn in eyes.
Owner:OPHTECS CORP
Packaging Solutions
InactiveUS20090173044A1Preserve sterilityImprove the lubrication effectLens cleaning compositionsPackage sterilisationEngineeringWater soluble
Packaging systems for storing ophthalmic devices such as contact lenses and to methods for packaging such ophthalmic devices with solutions to improve the comfort of the lenses during wear are disclosed. A packaging system includes an ophthalmic device stored in an aqueous packaging solution comprising a substantially water-soluble silicone-containing surfactant. Such solutions are retained on the surface of an unused lens for extended periods of time, resulting in surface modification that persists in the eye, which may provide significant improvement in the wetting properties of fresh contact lenses used for the first time and, moreover, even several hours after lens insertion, preventing dryness and improving lubricity.
Owner:BARCLAYS BANK PLC AS SUCCESSOR AGENT
Radiation-absorbing materials, ophthalmic compositions containing same, and method of treating ophthalmic devices
An ophthalmic composition includes a hydrophilic radiation-absorbing material, which includes a radiation-absorbing moiety coupled with a hydrophilic moiety. An ophthalmic device immersed in such a composition can obtain a radiation-absorbing property and provide protection to the wearer against such radiation. The ophthalmic composition can be formulated to achieve an effect selected from cleaning, sterilizing, storing, and combinations thereof.
Owner:BAUSCH & LOMB INC
Packaging Solutions
InactiveUS20100162661A1Preserve sterilityImprove wettabilityLens cleaning compositionsPackage sterilisationBoronic acidMacromonomer
Packaging systems for storing ophthalmic devices such as contact lenses and to methods for packaging such ophthalmic devices with solutions to improve the comfort of the lenses during wear are disclosed. A packaging system includes an ophthalmic device stored in an aqueous packaging solution comprising a brush copolymer comprising (a) monomeric units derived from an ethylenically unsaturated monomer containing one or more boronic acid moieties; and (b) monomeric units derived from an ethylenically unsaturated-containing hydrophilic macromonomer.
Owner:BARCLAYS BANK PLC AS SUCCESSOR AGENT
Lens care composition and method
ActiveUS20040142829A1Improve effectivenessLens cleaning compositionsSurface-active detergent compositionsChlorideTonicity
An buffered aqueous contact lens disinfecting solution having much lower concentration of disinfecting agents, and less irritating to the eye. The solutions have a tonicity of 200 to 450 mOsm / kg, a pH of between 6 and 8, and a concentration of chloride ions below 1500 ppm. Despite having less than 1 ppm of antimicrobial, the solutions are effective against C. albicans within 15 minutes of contact.
Owner:ALCON INC
Pharmaceutical formulations comprising polyanionic materials and zinc-based preservatives
InactiveUS20070212420A1Improve securityImprove comfortInorganic/elemental detergent compounding agentsBiocideMicroorganismMedicine
An improved pharmaceutical formulation that is effective in adversely affecting the viability of microorganisms or in inhibiting their growth and that provides better safety and / or comfort to the users. The pharmaceutical formulation comprises at least a polyanionic material and at least a zinc-based compound.
Owner:BAUSCH & LOMB INC
Ophthalmic compositions comprising diglycine
An ophthalmic composition that includes an epithelium cell stabilizer component. The epithelium cell stabilizer component may be one or more of diglycine, triglycine, tetraglycine, pentaglycine. The invention is also directed to a method of treating or preventing dry eye comprising administering an effective amount of the ophthalmic composition to the eye.
Owner:BAUSCH & LOMB INC
Use of multifunctional surface active agents to clean contact lenses
ActiveUS6995123B2Easy to cleanSufficient hydrophobicityOrganic detergent compounding agentsLens cleaning compositionsOrganic chemistrySURFACTANT BLEND
Cleaning compositions for contact lenses are described. The compositions contain multifunctional anionic surfactants that include at least two hydrophilic dissociating head groups. The multifunctional surfactants described (e.g., LED3A) possess both surface active and chelating properties, and have been found to be particularly effective in removing protein deposits from contact lenses.
Owner:ALCON INC
Ophthalmic and contact lens solutions containing simple saccharides as preservative enhancers
InactiveUS20070098818A1Effective preservationDegree of reductionBiocideHydroxy compound active ingredientsTagatoseSucrose
The present invention relates to an ophthalmic solution comprising 0.00001 to 10.0 weight percent of a simple saccharide, at least 0.00001 weight percent of a preservative, and not more than about 0.2 percent by weight chloride. The simple saccharide is chosen from the group consisting of: inositol; mannitol; sorbitol; sucrose; dextrose; glycerin; propylene glycol; ribose; triose; tetrose; erythrose; threose; pentose; arabinose; ribulose; xylose; xylulose; lyxose; hexose; allose; altrose; fructose; galactose; glucose; gulose; idose; mannose; sorbose; talose; tagatose; adlose; ketose; heptose; sedoheptulose; monosaccharides; disaccharides; sugar alcohols; xylitol; and polyol.
Owner:FXS VENTURES LLC
Method for sterilization of hydrogel contact lenses
InactiveUS20070195261A1Reduce sensitivitySufficient amountLens cleaning compositionsSurface-active detergent compositionsTonicityAqueous solution
The present invention provides an aqueous solution for sterilizing and storing ophthalmic devices, preferably a contact lens, made of a hydrogel material, preferably a poly(oxyalkylene)-containing hydrogel material. The solution comprises one or more organic buffer agents, such as a Good buffer or a bis-aminopolyols; an organic tonicity-adjusting agent with multiple hydroxyl groups in an amount sufficient to provide an osmolarity of from about 200 to about 450 mosm / l, wherein the aqueous solution has a pH of from about 5.5 to about 8.5, provided that the aqueous solution include phosphate buffer at a concentration of about 15 mM or less and about 5000 ppm sodium chloride. The present invention also provides a method for sterilizing and storing an ophthalmic device using an aqueous solution of the invention.
Owner:NOVARTIS AG
Ophthalmic Compositions Comprising a Branched, Glycerol Monoalkyl Compound and a Fatty Acid Monoester
InactiveUS20070286767A1Inhibition formationDestabilize foamCosmetic preparationsOrganic detergent compounding agentsGlycerolFatty acid
An aqueous ophthalmic composition comprising a branched, glycerol monoalkyl compound and a fatty acid monoester. The fatty acid monoester comprises an aliphatic fatty acid portion having six to fourteen carbon atoms and an aliphatic hydroxyl portion. The composition will also have an osmolality in a range from 200 mOsmol / kg to 400 mOsmol / kg. The invention is also directed to a method of inhibiting the formation of foam in an aqueous ophthalmic composition that includes a surfactant as well as to a method of enhancing the biocidal efficacy of an aqueous ophthalmic composition containing a fatty acid monoester.
Owner:BAUSCH & LOMB INC
Polypeptide with reduced allergenicity
The invention relates to modified polypeptides with reduced allergenicity comprising a parent polypeptide with a molecular weight from between 10 kDa and 100 kDa conjugated to a polymer with a molecular weight (Mr) in the range of 1 kDa and 60 kDa. The modified polypeptide are produced using a process including the step of conjugating from 1 to 30 polymer molecules with the parent polypeptide. Further the invention relates to compositions comprising said polypeptides and further ingredients normally used in e.g. detergents, including dishwashing detergents and soap bars, household article, agrochemicals, personal care products, cosmetics, toiletries, oral and dermal pharmaceuticals, composition for treating textiles, and compositions used for manufacturing food and feed. Finally the invention is directed to uses of polypeptides with reduced allergenicity or compositions thereof for reducing the allergenicity of products for a vast number of industrial applications.
Owner:NOVOZYMES AS
Solutions for ophthalmic lenses containing at least one silicone containing component
InactiveUS20100152084A1Inorganic/elemental detergent compounding agentsOrganic detergent compounding agentsEye lensPolymer
The present invention relates to a method for reducing the occurrence of superficial punctate staining comprising the step of packaging, storing or contacting an uncoated ophthalmic lens comprising at least one polymeric wetting agent and polymer units derived from at least one silicone containing component in a solution comprising an osmolality of about 220 mOsm / kg or greater.
Owner:JOHNSON & JOHNSON VISION CARE INC
Methods of inhibiting the adherence of lenses to their packaging
Owner:JOHNSON & JOHNSON VISION CARE INC
Use of a cationic polysaccharide to enhance biocidal efficacies
InactiveUS20050119221A1High bactericidal activityEnhanced disinfection preservationAntibacterial agentsBiocideMicrobial agentPolysaccharide
The use of a composition of one or more cationic polysaccharides in combination with one or more antimicrobial agents to disinfect contact lenses and preserve ophthalmic lens compositions is described. Ophthalmic lens solutions containing compositions of one or more cationic polysaccharides in combination with one or more antimicrobial agents and methods of making and using the same are also described.
Owner:BAUSCH & LOMB INC
One-pack preparation for disinfection, neutralization and cleaning of contact lenses and method of disinfection, neutralization and cleaning
The present invention provides a combined formulation for disinfecting, neutralizing and cleaning a soft contact lens and a method using the same easily, efficiently and safely. The formulation is a one-solution type of combined formulation for disinfecting, neutralizing and cleaning a soft contact lens, which includes a first formulation that contains an iodine-based disinfectant and a proteolytic enzyme and a second formulation that contains a reducing and a foaming agent treated with a delayed release coating, and which contains a nonionic surfactant in at least one of the first and second formulations. A stained soft contact lens can be disinfected, neutralized and cleaned easily by holding it in an aqueous solution colored yellow or brown by iodine molecules and removing it from the aqueous solution after the solution becomes almost colorless.
Owner:OPHTECS CORP
Contact lens wetting solution
InactiveUS20060217276A1Less discomfortReduce frictionInorganic/elemental detergent compounding agentsSenses disorderCarbon numberMonomer composition
Contact lens wetting solutions for reducing friction between the contact lens and ocular tissues, and maintaining such effect for a long time, are disclosed. The wetting solution is composed only of a particular ratio of a lubricant composed of copolymer (A) obtained by polymerizing a monomer composition comprising 2-(meth)acryloyloxyethyl phosphorylcholine and alkyl(meth)acrylate, a buffer, an inorganic chloride, a preservative, a chelating agent, and water. The copolymer (A) has a weight average molecular weight of 100,000 to 1,000,000, and satisfies the formula 80≦N×R≦240, provided that 4≦N≦18 and 10%≦R≦60%, wherein N stands for the carbon number of the alkyl group in monomer Y constituting copolymer (A), and R stands for a molar fraction of the unit derived from monomer Y with respect to the sum of the units derived from monomers X and Y.
Owner:NOF CORP +2
Bacterial attachment reduction to biomaterials and biomedical devices
InactiveUS20060205621A1Avoid stickingOrganic detergent compounding agentsLens cleaning compositionsMicroorganismBiological materials
Compositions for inhibiting attachment of microorganisms to the surface of biomaterials include a polyether, such as a poloxamer. The compositions are especially useful for treating contact lenses to prevent bacterial attachment to the lens.
Owner:BAUSCH & LOMB INC
Methods and compositions for controlling biofilm development
A method of cleaning or protecting surfaces by treatment with compositions comprising N-(3-oxododecanoyl)-L-homoserine lactone (OdDHL) blocking compounds and / or N-butyryl-L-homoserine lactone (BHL) analogs, either in combination or separately.
Owner:MONTANA STATE UNIVERSITY
Artificial tear, contact lens and drug vehicle compositions and methods of use thereof
PendingUS20180098937A1Enhancing contact lens wear timeReduce decreaseOrganic active ingredientsSenses disorderPolyolMedicine
The invention provides artificial tear compositions, artificial tear-gel compositions, contact lens storage compositions, contact lens treatment compositions, ophthalmological drug vehicle compositions and topical drug vehicle compositions comprising one or more nonionic surfactants with one or more non-Newtonian viscosity enhancing excipients and one or more of a polyol and or an electrolyte and methods of their use.
Owner:PS THERAPIES LTD +1
Compositions and methods for cleaning contact lenses
ActiveUS20020141899A1Free from damageReducing and substantially eliminatingBiocideOrganic detergent compounding agentsHydrophileHydrophobe
A composition for disinfecting a contact lens comprising an effective disinfecting amount of hydrogen peroxide and a surfactant comprising a copolymer of hydrophobe and hydrophile blocks the structure:<paragraph lvl="0"><in-line-formula>HO-(hydrophobe)x-(hydrophile)y-(hydrophobe)x-H< / in-line-formula><paragraph lvl="0"><in-line-formula>or< / in-line-formula><paragraph lvl="0"><in-line-formula>HO-(hydrophile)y-(hydrophobe)x-(hydrophile)y-H< / in-line-formula>where x and y are integers reflecting the respective hydrophile and hydrophobe blocks of said copolymer; and the hydrophile component of the block copolymer constitutes less than 50 weight percent of the block copolymer. The block copolymer has a Ross-Miles foam height (ASTM designation D-1173-53; 0.1%, at 50° C.) of less than 1 mm.
Owner:ALCON INC
Methods of sterilizing polymers
InactiveUS6139794AEfficient heat transferReduce oxidationInorganic/elemental detergent compounding agentsLens cleaning compositionsPolymer scienceOrganic fluid
Owner:ALCON RES LTD
Opthalmic compositions with an amphoteric surfactant and an anionic biopolymer
Ophthalmic compositions that comprise 0.1 ppm to 50 ppm of a cationic antimicrobial component selected from the group consisting of biguanides, polymeric biguanides, quaternium ammonium compounds and any one mixture thereof; 0.005 wt. % to 2 wt. % of an anionic biopolymer; and 0.01 wt. % to 2 wt. % of an amphoteric surfactant of general formula Iwherein R1 is R or —(CH2)n—NHC(O)R, wherein R is a C8-C30alkyl optionally substituted with hydroxyl and n is 2, 3 or 4; R2 and R3 are each independently selected from C1-C4alkyl; R4 is a C2-C8alkylene optionally substituted with hydroxyl; and Y is CO2− or SO3. The invention is also direct to the use of the ophthalmic compositions to clean and disinfect contact lenses, and in particular, soft, silicone hydrogel contact lenses.
Owner:BAUSCH & LOMB INC
Method and composition for reducing contact lens swelling
InactiveUS7037469B2Preserve visual acuityLonger lasting wetting performanceSenses disorderCationic surface-active compoundsHigh concentrationControlled release
The present invention is directed to an ophthalmic solution for soft contact lenses for controlled release of polyethers into an eye's tear film. Polyether components of the subject solution are released from the soft contact lens material matrix over long time periods to produce longer lasting wetting performance, improved lubricity, improved end-of-the-day comfort and reduced feeling of dryness from wearing contact lenses. The present invention also includes the use of cationic polyelectrolytes for controlling the swelling of hydrogel contact lenses typically caused by the absorption of high concentrations of polyethers.
Owner:BAUSCH & LOMB INC
Compositions and methods for cleaning contact lenses
A composition for disinfecting a contact lens comprising an effective disinfecting amount of hydrogen peroxide and a surfactant comprising a copolymer of hydrophobe and hydrophile blocks the structure:HO-(hydrophobe)x-(hydrophile)y-(hydrophobe)x-HorHO-(hydrophile)y-(hydrophobe)x-(hydrophile)y-Hwhere x and y are integers reflecting the respective hydrophile and hydrophobe blocks of said copolymer; and the hydrophile component of the block copolymer constitutes less than 50 weight percent of the block copolymer. The block copolymer has a Ross-Miles foam height (ASTM designation D-1173-53; 0.1%, at 50° C.) of less than 1 mm.
Owner:ALCON INC
Polymeric quaternium compounds
InactiveUS8349303B1Lens cleaning compositionsSynthetic polymeric active ingredientsMedicinal chemistryPolymer science
A topical pharmaceutical composition comprising a pharmaceutical active and a polymer of general formula I or general formula IIwherein Ck is a saturated or unsaturated, five, six or seven-membered ring;R is a C1-C3alkyl; n is 1, 2, 3, 4 or 5 and m provides a number average molecular weight of the polymer of from 2000 to 80,000.
Owner:BAUSCH & LOMB INC
Process for purifying and reusing solvent used to remove extractables
InactiveUS7022813B2Speed up the processInorganic/elemental detergent compounding agentsLens cleaning compositionsSolventPolymer
A process for treating biomedical devices, especially contact lenses, involves contacting polymeric devices containing extractables with a solvent that dissolves and thereby removes the extractables from the device, treating the solvent to remove extractables from the solvent, thereby purifying the solvent, and using the purified solvent to remove additional extractables from polymeric devices.
Owner:BARCLAYS BANK PLC AS SUCCESSOR AGENT
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