55results about "Lens cleaning compositions" patented technology

A contact lens treating solution includes (a) about 0.005 to about 2 wt. %, based on the total weight of the contact lens treating solution, of hyaluronic acid or a salt thereof; (b) about 0.01 to about 1 wt. %, based on the total weight of the contact lens treating solution, of erythritol; (c) one or more nonionic surfactants; (d) sodium chloride, potassium chloride or any combination thereof; and (e) one or more buffers.

The present disclosure provides a novel polypeptide. Also provided is an ophthalmic composition for treating or preventing dry eye (DE) or DE associated disorders. Also provided is a method for treating or preventing DE or DE associated disorders, stimulating tears, stabilizing tear film or any combination thereof in a subject in need thereof, comprising administering to the subject an effective amount of the novel peptides. Also provided is a contact lenses care product comprising the novel peptides and the preparation method thereof.

Provided is a soft contact lens solution that imparts surface hydrophilicity, lubricity, and a lipid adhesion-suppressing ability to a soft contact lens. It has been found that a solution containing two specific kinds of copolymers and a buffering agent can achieve the above-mentioned object. Thus, the soft contact lens solution of the present disclosure has been completed.

The present disclosure provides a novel polypeptide. Also provided is an ophthalmic composition for treating or preventing dry eye (DE) or DE associated disorders. Also provided is a method for treating or preventing DE or DE associated disorders, stimulating tears, stabilizing tear film or any combination thereof in a subject in need thereof, comprising administering to the subject an effective amount of the novel peptides. Also provided is a contact lenses care product comprising the novel peptides and the preparation method thereof.

Sterile compositions comprising an aqueous carrier and liposomes, wherein a mean diameter and / or zeta potential of the liposomes changes by no more than 20 % over the course of 300 days, are described herein; as well as processes for preparing such compositions by subjecting an aqueous composition comprising the aqueous carrier and liposomes to a temperature of over 100 °C. Further described are processes for preparing a sterile article of manufacture having lipids attached thereto, by contacting the article of manufacture with an aqueous composition comprising an aqueous carrier and liposomes, and subjecting it to a temperature of over 100 °C; as well as sterile articles of manufacture prepared according to a process described herein. The liposomes comprise a bilayer-forming lipid and a polymeric compound having the formula (I). wherein m, n, L, X, Y and Z are as defined herein.

The ophthalmically compatible solution comprises: (a) about 0.005 to about 2% by weight of hyaluronic acid or a salt thereof, based on the total weight of the ophthalmically compatible solution; (b) about 0.01 to about 1% by weight of erythritol, based on the total weight of the ophthalmically compatible solution; (c) sodium chloride, potassium chloride, or any combination thereof; and (d) one or more buffering agents.

A contact lens treating solution includes (a) about 0.005 to about 2 wt. %, based on the total weight of the contact lens treating solution, of hyaluronic acid or a salt thereof; (b) about 0.01 to about 1 wt. %, based on the total weight of the contact lens treating solution, of erythritol; (c) one or more nonionic surfactants; (d) sodium chloride, potassium chloride or any combination thereof; and (e) one or more buffers.

The contact lens treatment solution comprises: (a) one or more potassium salts selected from the group consisting of potassium chloride, potassium citrate, potassium hydroxide, potassium borate, potassium ethylenediaminetetraacetate, and potassium phosphate; (b) an antimicrobial agent comprising alexidine or a salt or free base thereof; and (c) optionally, one or more sodium salts selected from the group consisting of sodium chloride, sodium citrate, sodium hydroxide, sodium phosphate, sodium ethylenediaminetetraacetate, and sodium borate, wherein, when one or more sodium salts are present, the one or more potassium salts are present in an amount greater than the amount of the one or more sodium salts.

A silicone hydrogel contact lens is described comprising an extractable amount of a hydroxyalkyl cellulose embedded in the silicone hydrogel. The presence of the hydroxyalkyl cellulose in the silicone material improves the wettability of the contact lens.

A method for disinfecting contact lenses, including immersing the contact lenses in a volume of cleaning agent with about 3% hydrogen peroxide for up to 4hrs, and immersing up to 0.7g of a fibrous catalyst enhancer material in the volume of cleaning agent for up to 4hrs. The fibrous catalyst enhancer material is immersed simultaneously with the contact lenses.

[Problem] To provide a treatment fluid for a soft contact lens that can easily provide hydrophilic and lubricating properties to a surface of a contact lens, and has superior persistence. [Solution] A treatment fluid for a soft contact lens according to the present disclosure was achieved by dissolving a copolymer in a solution at a specific concentration, said copolymer being obtained by copolymerizing at least two specific types of monomers.

The invention relates to a lipase-containing composition for cleaning contact lenses, in particular soft contact lenses, characterized in that the composition contains a lipase that is obtainable from the yeast Candida rugose.

A preservative-free contact lens treating solution includes (a) about 0.005 to about 2 wt. %, based on the total weight of the preservative-free contact lens treating solution, of hyaluronic acid or a salt thereof; (b) about 0.01 to about 1 wt. %, based on the total weight of the preservative-free contact lens treating solution, of erythritol; (c) one or more nonionic surfactants; (d) sodium chloride, potassium chloride or any combination thereof; and (e) one or more buffers.

A glycophospholipid polymer is disclosed. This glycophospholipid polymer comprises a reaction product of one or more glycosaminoglycans and one or more phospholipids. A glycophospholipid polymer network comprising a reaction product of one or more glycosaminoglycans, one or more phospholipids, and one or more crosslinking agents is also disclosed.

The present invention relates to a lipase-containing composition for cleaning contact lenses, in particular soft contact lenses, where the composition contains a lipase obtainable from Candida rugosa.

A grafted glycosaminoglycan polymer is disclosed. The grafted glycosaminoglycan polymer comprises a glycosaminoglycan having a polymer backbone and one or more side chains comprising a polyalkylene glycol-containing residue grafted onto the polymer backbone.

A contact lens treating solution includes (a) one or more potassium salts selected from the group consisting of potassium chloride, potassium citrate, potassium hydroxide, potassium borate, potassium ethylenediaminetetraacetic acid and potassium phosphate, (b) an antimicrobial agent comprising alexidine or a salt or a free base thereof, and (c) optionally, one or more sodium salts selected from the group consisting of sodium chloride, sodium citrate, sodium hydroxide, sodium phosphate, sodium ethylenediaminetetraacetic acid and sodium borate, wherein the one or more potassium salts are present in an amount greater than an amount of the one or more sodium salts when present.

To provide techniques for solidification of liquid amine oxide, betaine, and / or sultaine surfactants with a carrier to form a solidified surfactant composition.SOLUTION: In particular, the invention relates to solidification of liquid surfactants utilizing one or more drying devices, wherein the feed composition contains at least one liquid surfactant and a carrier to form a solidified surfactant composition. The solidified surfactant compositions can be useful in various cleaning compositions.SELECTED DRAWING: None

The invention relates to solidification of liquid amine oxide, betaine, and / or sultaine surfactants with a carrier to form a solidified surfactant composition. In particular, the invention relates to solidification of liquid surfactants utilizing drying device(s), wherein the feed composition contains at least one liquid surfactant and a carrier to form a solidified surfactant composition. The solidified surfactant compositions can be useful in various cleaning compositions.

The present disclosure provides a liquid composition for preserving contact lenses. The liquid composition includes a buffer solution, a zinc salt dissolved in the buffer solution, and a hydrophilic substance. The weight percentage concentration of the zinc salt in the liquid composition is 1 * 10 <-5 >-3%. The weight percentage concentration of the hydrophilic substance in the liquid composition is 1 * 10 <-3 >% to 3%. The liquid composition may also include a first vitamin dissolved in the buffer solution. The weight percentage concentration of the first vitamin in the liquid composition is 1 * 10 <-5 >% to 1%, and the first vitamin comprises vitamin B2, a vitamin B2 derivative, or a combination thereof. According to the present invention, the novel liquid composition is provided to preserve the contact lens, such that the contact lens wearing feeling can be effectively improved, and the health state of the cornea can be easily maintained.

Systems and methods for cleaning a hard-coated ophthalmic lens and stripping the hard- coating of the hard coated ophthalmic lens in a single pass process are disclosed. The hard-coated ophthalmic lens is sequentially treated with a cleaning solution, an alkaline solution, and a stripping solution. Ultrasonic power is applied to the solutions and the ophthalmic lens during the process. The resulted ophthalmic lens has substantially no sign of chemical attack or residual hard coating or varnishes thereon.

To provide a solution for soft contact lens that imparts surface hydrophilicity and antifouling properties to a soft contact lens by using a solution containing a compound Q represented by a formula (a).

The invention discloses a preparation process of a cleaning and disinfecting solution and a neutralizing tablet for an orthokeratology lens, which comprises the following steps: firstly, selecting high-purity hydrogen peroxide, and adding a stabilizer, a pH regulator and the like to prepare 3% hydrogen peroxide; secondly, selecting Korean polyethylene glycol 6000, Germany BASF poloxamer 407, analytic-grade EDTA (Ethylene Diamine Tetraacetic Acid)-disodium, catalase and the like to prepare a neutralizing tablet; 3% hydrogen peroxide and the neutralization tablet are subjected to a neutralization reaction, and the cleaning and disinfection capacity and hydrogen peroxide and enzyme preparation residues are measured. The cleaning disinfectant for the orthokeratology lens, disclosed by the invention, is stable in property and good in sterilizing effect after being compounded; a high-activity enzyme preparation and a surfactant are added into the neutralization tablet and are efficient in neutralization, high in cleaning and disinfecting capacity and free of drug resistance; nursing is simple, no residues exist, eye irritation is avoided, and the liquid can directly enter eyes after being cleaned and disinfected; the lens does not need to be rubbed in the nursing process, the lens damage risk is greatly reduced, and it is guaranteed that the lens is convenient to use.

A contact lens treating solution includes (a) one or more of tris(hydroxymethyl)aminomethane, bis(2-hydroxyethyl)amino-tris(hydroxymethyl)methane and a salt thereof; and (b) one or more antimicrobial agents comprising one or more polyquaternium polymers.

The contact lens treatment solution comprises: (a) from about 0.005 to about 2% by weight of hyaluronic acid or a salt thereof, based on the total weight of the contact lens treatment solution; (b) from about 0.01 to about 1% by weight of erythritol, based on the total weight of the contact lens treatment solution; (c) one or more nonionic surfactants; (d) sodium chloride, potassium chloride, or any combination thereof; and (e) one or more buffering agents.

To provide a polymer for use as a coating of biomedical devices such as contact lenses.SOLUTION: A grafted glycosaminoglycan polymer which is a reaction product of (a) a glycosaminoglycan having a polymer backbone containing reactive functional groups, wherein any of the reactive functional groups is an epoxide-reactive functional group, (b) a polyol, and (c) an epoxy alcohol, the grafted glycosaminoglycan polymer comprising one or more side chains including a polyalkylene glycol-containing residue grafted to the epoxide-reactive functional group of the polymer backbone of the glycosaminoglycan, the polyalkylene glycol-containing residue being derived from a polymeric compound or a salt thereof having the following structure: Z-(((CH2)a-O)b)c-Y (wherein Z is a terminal capping group, Y is a reactive functional group, a is 2 to 6, b is 2 to 10,000, and c is 1 or 2).SELECTED DRAWING: None

A packaging system for the storage of an ophthalmic device is disclosed. The packaging system includes a sealed container containing one or more unused ophthalmic devices immersed in an aqueous packaging solution that includes one or more conjugated glycosaminoglycans having a polymer backbone having a reactive functional moiety conjugated to an amine group having one or more moieties that inhibit and / or prevent one or more of oxidation and hydrolytic degradation of the polymer backbone during use in the eye; wherein the aqueous packaging solution has an osmolality of at least about 150 mOsm / kg, a pH of about 6 to about 9 and is sterilized.

The invention provides a fragrant glasses cleaning solution and a preparation method thereof, and relates to the technical field of glasses cleaning solutions. The invention relates to an antibacterial perfume, which is prepared from the following ingredients in parts by weight: 0.8 to 2 parts of fragrant microcapsules, 0.3 to 1 part of polyether modified silicone oil, 0.05 to 0.1 part of modified nano silicon dioxide, 1.5 to 3 parts of glycerinum, 0.5 to 2 parts of compound antibacterial agents, 0.3 to 0.5 part of ethylene diamine tetraacetic acid disodium salt, 8 to 12 parts of alcohols and 78 to 88 parts of deionized water. Wherein the fragrant microcapsules are prepared by wrapping essence in beta-cyclodextrin-chitosan composite microspheres, the composite antibacterial agent comprises benzalkonium chloride and polyhexamethylene biguanide in a weight ratio of (2.5-3.5): 1, and the pH value of the cleaning solution is 6-8. Through microcapsule slow release and pH control, the irritation of the cleaning liquid to eyes is reduced, and the fragrance can last for 8-10 hours; glycerin and polyether modified silicone oil have a synergistic effect, so that the antifogging time of the lens is prolonged to 72 hours, the antibacterial rate within 5 minutes can reach 99.9%, and the wear rate of 100-time coating is less than 0.1%.

The present disclosure provides novel polypeptides. Also provided are ophthalmic compositions for treating or preventing dry eye (DE) or DE-related disorders. Also provided are methods for treating or preventing DE or DE-related disorders in a subject in need thereof, stimulating tear fluid, stabilizing tear film, or any combination thereof, comprising administering to the subject an effective amount of the novel peptide. Also provided are contact lens care products comprising the novel peptides and methods for preparing the same.