This invention relates to a
drug-loaded
polypyrrole interdigitated
microelectrode, its preparation method, and its application. The
electrode comprises: a biocompatible
metal substrate, an insulating layer disposed on the surface of the biocompatible
metal substrate, a
polypyrrole interdigitated
microelectrode structure disposed on the insulating layer, and a bioactive
drug loaded in the
polypyrrole interdigitated
microelectrode. In the preparation method, the insulating layer is first formed through pretreatment, and then the
pyrrole monomer is rapidly and uniformly oxidized and polymerized to form a denser thin film using the high anodic potential of the
interdigitated electrode. This invention can be applied to intelligent bone implants, enabling the simultaneous integration of therapeutic and diagnostic functions without compromising the mechanical properties of the
implant, thereby significantly improving the success rate and long-term stability of the
implant.