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6results about How to "Guaranteed biocompatibility" patented technology

High-toughness plastic for medical needle tube and preparation method of high-toughness plastic

PendingCN121851664AGuaranteed biocompatibilityImprove long-term antibacterial effectCellulosePolymer science
The invention discloses a high-toughness plastic for a medical needle tube and a preparation method of the high-toughness plastic, and belongs to the technical field of polymer composite materials. The product comprises the following components: polycaprolactone, maleic anhydride grafted polylactic acid, a chitosan modified hydroxypropyl methyl cellulose derived carbon dot bacteriostatic agent and the like. The preparation method comprises the steps of preparation of the carbon dot bacteriostatic agent, pretreatment of raw materials, preparation of the functionalized master batch, segmented temperature control twin-screw extrusion melt blending and the like. The composite carbon dot bacteriostatic agent is constructed by hydrothermal carbonization-two-step amidation grafting, and is matched with the functionalized master batch preparation and interface regulation and control technology, so that the problems that the bacteriostatic agent of the existing medical needle tube material is easy to migrate, poor in compatibility and insufficient in toughness are solved, the synergistic improvement of long-term bacteriostasis and high toughness is realized, the biocompatibility is guaranteed, and the medical needle tube material has a good application prospect. The device is suitable for intrusive medical instruments such as medical needle tubes.
Owner:HUNAN SITODE MEDICAL EQUIP CO LTD

Preparation method and application of high-efficiency emergency antibacterial dressing

PendingCN122643490AGood moisture absorption and air permeabilityImprove breathabilityFreeze-dryingWound.exudate
The application provides a preparation method and application of a high-efficiency emergency antibacterial dressing and belongs to the technical field of biomedical materials. The high-efficiency emergency antibacterial dressing is prepared through a systematic process of alcohol-free wet spinning, secondary traction stretching, vacuum freeze drying, semi-dry state rapid carboxymethylation and needle punching / water jetting into cloth. The high-efficiency emergency antibacterial dressing has high mechanical strength and strong liquid absorption capacity, can absorb a large amount of wound exudate and keep the wound moist, and realizes the synergistic effect of multiple functions such as emergency, anti-adhesion, strong stability, antibiosis and repair promotion.
Owner:HUAZHONG AGRI UNIV

A sustained release system for oral care products and methods of making and using the same

PendingCN122499042AReduced diffusion rateLong-lasting remineralization repair
This invention belongs to the field of compositions of polymeric compounds for oral care products, specifically relating to a sustained-release system for oral care products, its preparation method, and its application. This invention discloses that when a cationic polymeric compound, sodium alginate, and ectoine are used in combination, a unique OraReliX™ sustained-release system can be formed on the tooth surface. The core working principle of this system is as follows: the cationic substance adheres to the negatively charged tooth surface through electrostatic adsorption, forming a cationic network; sodium alginate regulates the network density through polyelectrolyte complexation with this cationic network, while reversibly binding calcium ions; ectoine stabilizes the oral microenvironment and protects the sustained-release network structure. The synergistic effect of these three components significantly slows down the release rate of calcium ions, prolonging their effective retention time in the oral cavity.
Owner:JIANGSU MANWEI PHARM CO LTD

Gluing device for recombinant collagen dressing patch production

The utility model relates to the technical field of gluing production equipment, in particular to a gluing device for recombined collagen dressing paste production, which comprises a box body, a conveying roller is rotatably connected to an inner cavity of the box body, a bearing plate is welded to the inner cavity of the box body, a gluing roller is rotatably connected to one side opposite to the bearing plate, and the conveying roller is welded to the inner cavity of the box body. A material storage frame is welded to an inner cavity of the box body, through holes are formed in the surface of the box body, an adjusting mechanism is arranged on the surface of the box body and comprises a supporting plate, and the supporting plate is welded to the surface of the box body. Through cooperation of the conveying roller, the supporting plate, the driving motor, the rotating rod, the stirring blades and the transmission belt, the gluing device and an automatic production line of the conveying roller are integrated, full-automatic production from raw material conveying to gluing is achieved, the multiple sets of stirring blades are integrated, good quality can be kept in the using process, and the production efficiency is improved. The biocompatibility of the product is ensured, and the production efficiency is improved.
Owner:SHANXI BAITEHUI MEDICAL TECH CO LTD

Drug-loaded polypyrrole interdigitated microelectrodes, their preparation methods and applications

PendingCN122075790ASolve the problem of declining mechanical propertiesGuaranteed biocompatibilityInternal electrodesCoatingsPolypyrroleBiocompatibility
This invention relates to a drug-loaded polypyrrole interdigitated microelectrode, its preparation method, and its application. The electrode comprises: a biocompatible metal substrate, an insulating layer disposed on the surface of the biocompatible metal substrate, a polypyrrole interdigitated microelectrode structure disposed on the insulating layer, and a bioactive drug loaded in the polypyrrole interdigitated microelectrode. In the preparation method, the insulating layer is first formed through pretreatment, and then the pyrrole monomer is rapidly and uniformly oxidized and polymerized to form a denser thin film using the high anodic potential of the interdigitated electrode. This invention can be applied to intelligent bone implants, enabling the simultaneous integration of therapeutic and diagnostic functions without compromising the mechanical properties of the implant, thereby significantly improving the success rate and long-term stability of the implant.
Owner:HEBEI UNIV OF TECH