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70 results about "Prior treatment" patented technology

Prior therapy. Any therapy given to a patient for a particular condition before starting a new regimen for managing the same condition. Prior therapy is of particular interest when enrolling a patient in a clinical study or trial.

Method and Apparatus for Treatment of Tinnitus and Other Neurological Disorders by Brain Stimulation in the Inferior Colliculi and/or In Adjacent Areas

InactiveUS20070265683A1Reducing and eliminating effectSuppress and eliminate neural activityHead electrodesImplantable neurostimulatorsPeriaqueductal grayElectrode placement
Electrical stimulation is applied to the inferior colliculus or colliculi (IC), in order to diminish tinnitus by revising auditory pathway neuronal activity. This intervention diminishes tinnitus and treats other neurological and otological disorders. The locations and methods of electrode placement and anchoring and the structure of the electrodes are an advance over prior treatments. Other treatment locations in the nearby region of the IC, including the superior colliculi (SC) and Peri-aqueductal gray (PAG), provide treatments for other disorders and symptoms such as partial hearing loss and pain. The IC is a unique choice for the treatment of tinnitus and other disorders because an electrode placed in that region enables minimal invasiveness. The anchoring location also uniquely minimizes invasiveness by providing the option of residing in the meninges instead of the brain tissue. The shape of the electrode and its anchoring process uniquely match the brain's anatomy in order to provide greater specificity in diagnosis and treatment. Stimulation of areas near the IC, particularly the superior colliculus and peri-aqueductal gray, can be used to treat various neurological disorders. Customized feedback from the implantable system enables the creation of customized treatment programs.
Owner:EHRLICH DOV

Individualized cancer therapy

In certain embodiments, the invention provides methods for treating cancer, comprising: (a) obtaining a specimen of cancer tissue and normal tissue from a patient; (b) extracting total protein and RNA from the cancer tissue and normal tissue; (c) obtaining a protein expression profile of the cancer tissue and normal tissue; (d) identifying over-expressed proteins in the cancer tissue; (e) comparing the protein expression profile to a gene expression profile; (f) identifying at least one prioritized protein target by assessing connectivity of each said over-expressed protein to other cancer-related or stimulatory proteins; (g) designing a first RNA interference expression cassette to modulate the expression of at least one gene encoding the prioritized target protein; (h): designing a first RNA interference expression cassette to modulate the expression of at least one gene encoding a protein of higher priority in the signaling pathway in which the first protein is a component; (i) incorporating the first cassette into a first delivery vehicle; (j) providing a patient with an effective amount of the first delivery vehicle; (k) extracting total protein and RNA from the treated cancer tissue; (l) identifying over-expressed proteins in the treated cancer tissue; (m) designing a second RNA interference expression cassette to modulate the expression of a second prioritized protein in the treated tissue; (n) incorporating the second cassette into a second delivery vehicle; (o) providing the previously treated patient with an effective amount of the second delivery vehicle; (p) identifying a novel protein signal following prior treatment with protein specific knockdown; (q) identifying a gene mutation provided by gene sequencing / microarray on assessment of other protein signals; and (r) identifying of a novel protein signal as a result of determination of the gene mutation and assessment of other protein signals to, directly or indirectly, modify the expression (i.e., production) of such proteins.
Owner:GRADALIS

Laser magnetoelectric integrated therapeutic technique and multifunctional therapeutical instrument

The invention relates to a laser and magnetoelectricity comprehensive therapy and a multi-functional therapeutic instrument. The laser and magnetoelectricity comprehensive therapy is a comprehensive physical energy therapy without injecting and taking medicines, that is, the comprehensive energy of laser, a magnetic field, and an electric field acts on a human body to generate photochemical effect, magnetic water effect and electric effect, activate cells for promoting microcirculation, activate blood vessels for improving the activity of erythrocytes, reducing the aggregation of blood platelets and promoting blood circulation with oxygen, purify blood for promoting the metabolism of the human body, and stimulate channels and acupuncture points to ensure that an autonomic nerve is balanced further to resist and remove the damage of free radicals on the human body. The laser and magnetoelectricity comprehensive therapy and the multi-functional therapeutic instrument are used for the treatment of common diseases and frequently encountered diseases, the prevention of subhealthy state, health care, cosmetology, weight losing and so on. The comprehensive therapy is integrated with laser and magnetoelectricity, and the light, the magnetism and the electricity are compatible with one another in principle, so the prior treatment range of the laser, the magnetic field, the electric field and so on, is covered; and the laser and the magnetoelectricity comprehensively act on the human body, and the treatment effects of the laser and the magnetoelectricity are the superposition of various single physical energy therapies due to the all-round three-dimensional treatment.
Owner:徐瑛

Treatment device for orthopedic spinal injury

The invention relates to a treatment device for orthopedic spinal injury, which effectively solves the problems that the prior treatment device is single in function, inconvenient in use and high in cost and a patient is painful during treatment. The technical solution includes a seat base body and a storage box at the lower end. The seat base body is provided with a transfer pulley at the front end thereof. A bearing wheel seat of the transfer pulley has a telescopic rod cooperatively rotated thereon. A hand turntable is arranged rotatably and cooperatively on the upper end of the telescopicrod. Rotating handles are mounted on both sides of the hand turntable. The hand turntable cooperates with the transfer pulley in a transmission manner through a main belt. The transfer pulley is in transmission connection with a driving wheel arranged rotatably and cooperatively inside the storage box through an auxiliary belt. The driving wheel is coaxially matched with two unidirectional wheelswith opposite directions of rotation. The unidirectional wheels are rotatably matched with the storage box. The two unidirectional wheels control a lumbar vertebra tapping device and a back spine massaging device respectively. A cervical vertebra turning device controlled and driven by the same unidirectional wheel is arranged on the upper end of the back spine massaging device. The treatment device of the invention has the advantages of ingenious structure, strong practicability and good treatment effect of the patient.
Owner:HENAN PROVINCE HOSPITAL OF TCM THE SECOND AFFILIATED HOSPITAL OF HENAN UNIV OF TCM

High-temperature hydrolysis type oil-containing sediment harmless comprehensive treatment process

The invention relates to a high-temperature hydrolysis type oil-containing sediment harmless comprehensive treatment process. The invention mainly solves the problems that the prior treatment processof oil-containing sediment in oil fields is simple, and the treatment of oil-containing sediment which contains many impurities is not thorough. The treatment process is characterized by comprising the following steps: (1) sludge fluidization and pretreatment: discharging solid particles with a diameter larger than 5mm by a sorting box and a rotary drum separating device; (2) sludge tempering: sequentially introducing the conveyed mixture into three tempering tanks connected in series, conveying the oil-containing sediment separated by the tempering tanks to a two-phase centrifuge, and conveying the floating oil to an oil water separator; and (3) mechanical separation: carrying out solid liquid separation by the two-phase centrifuge, and carrying out oil water separation by the oil-water separator. The high-temperature hydrolysis type oil-containing sediment harmless comprehensive treatment process can be used to treat oil-containing sediment with different oil field types and complexcomponents, the reduction and harmless treatment of the oil-containing sludge can be effectively realized, the operation is simple, and the running cost is low.
Owner:袁东升

River course pollution remediation treatment technology

The invention discloses a river course pollution remediation treatment technology, relates to the field of river course treatment, and solves the problem that river course pollution cannot be fundamentally eliminated in a prior treatment method. The technology comprises the steps that one, a sewage discharging pipe is arranged in a river course; two, cut-off dikes are arranged at the two ends of the river course, and river water within the cut-off dikes is pumped to the downstream of the river course; three, microorganisms in sludge at the bottom of the river course are analyzed to obtain beneficial bacteria, and the beneficial bacteria are directionally proliferated to clear the sludge at the bottom of the river course; four, cleaned and clear river water is introduced into the river course, and the beneficial bacteria, aquatic creatures and a water quality regulating agent are put into the river course; five, the cut-off dikes are removed, and river water flows again. The technologyhas the advantages that the sewage discharging pipe is arranged in the river course, and the two ends of the sewage discharging pipe are directly communicated with a sewage discharging port and a sewage treatment plant to eliminate a sewage source of the river course and greatly reduce the source of the pollution; a manner in which the river course is treated by completely draining water is adopted, and the downstream of the river course can be effectively prevented from being affected by pollutants.
Owner:广州诺登环保工程有限公司

Individualized cancer therapy

In certain embodiments, the invention provides methods for treating cancer, comprising: (a) obtaining a specimen of cancer tissue and normal tissue from a patient; (b) extracting total protein and RNA from the cancer tissue and normal tissue; (c) obtaining a protein expression profile of the cancer tissue and normal tissue; (d) identifying over-expressed proteins in the cancer tissue; (e) comparing the protein expression profile to a gene expression profile; (f) identifying at least one prioritized protein target by assessing connectivity of each said over-expressed protein to other cancer-related or stimulatory proteins; (g) designing a first RNA interference expression cassette to modulate the expression of at least one gene encoding the prioritized target protein; (h): designing a first RNA interference expression cassette to modulate the expression of at least one gene encoding a protein of higher priority in the signaling pathway in which the first protein is a component; (i) incorporating the first cassette into a first delivery vehicle; (j) providing a patient with an effective amount of the first delivery vehicle; (k) extracting total protein and RNA from the treated cancer tissue; (l) identifying over-expressed proteins in the treated cancer tissue; (m) designing a second RNA interference expression cassette to modulate the expression of a second prioritized protein in the treated tissue; (n) incorporating the second cassette into a second delivery vehicle; (o) providing the previously treated patient with an effective amount of the second delivery vehicle; (p) identifying a novel protein signal following prior treatment with protein specific knockdown; (q) identifying a gene mutation provided by gene sequencing / microarray on assessment of other protein signals; and (r) identifying of a novel protein signal as a result of determination of the gene mutation and assessment of other protein signals to, directly or indirectly, modify the expression (i.e., production) of such proteins.
Owner:GRADALIS

Intelligent treatment system for photo-crosslinking operation and establishment method

The invention discloses an intelligent treatment system for a cornea photo-crosslinking operation. The intelligent treatment system comprises a corneal topography image collecting system, a photo-crosslinking operation guiding system and a prior-treatment corneal topography and photo-crosslinking operation parameter corresponding database; the corneal topography image collecting system is configured to collect corneal topography images of a user; the photo-crosslinking operation guiding system is configured to compare a corneal topography before corneal laser crosslinking with an expected postoperative corneal topography to output parameters of the photo-crosslinking operation; the prior-treatment corneal topography and photo-crosslinking operation parameter corresponding database is usedfor pre-training and correcting the photo-crosslinking operation guiding system. The corneal topography image collecting system obtains images and a corneal topography of a patient, then the corneal topography is input to the photo-crosslinking operation guiding system which is pre-trained by the prior-treatment corneal topography and photo-crosslinking operation parameter corresponding database,and then the parameters of the photo-crosslinking operation are obtained. The invention further discloses an establishment method of the intelligent treatment system. By means of the intelligent treatment system, an efficient, precise and stable treatment guidance can be provided for the cornea photo-crosslinking operation.
Owner:SHENZHEN GRADUATE SCHOOL TSINGHUA UNIV

Endoscopic minimally invasive hoe scaler

The invention discloses an endoscopic minimally invasive hoe scaler, comprising a catheter, hemostatic forceps, an operating grip and an operation control device. The endoscopic minimally invasive hoe scaler is characterized in that a head of the catheter is connected with the hemostatic forceps while a tail of the catheter is matched connection with the operating grip; the hemostatic forceps are composed of a subwarhead-shaped hollow binding clip of which two halves are closed and opened correspondingly; the hoe scaler is a plasma hoe scaler formed by a steel wire structure, and extends into a linked tube of the hemostatic forceps; the operating grip is provided with a hemostatic forceps push ring and a hoe scaler control grip capable of moving back and forth; and the operation control device comprises a hemostatic forceps operation control device and a hoe scaler operation control device. The endoscopic minimally invasive hoe scaler solves the defects in the prior treatment on digestive tumor, and comprises both the hoe scaler and the hemostatic forceps, so that cockamamie operations of repeatedly changing a plurality of prior instruments in the world at present are avoided; and after being powered on, the endoscopic minimally invasive hoe scaler has the functions of the biopsy forceps and the hemostatic forceps, and the function of incision, so that the detection, the incision and the haemostasis in time can be convenient, and the complications of bleeding can be reduced.
Owner:潘文胜

High-pressure earth mortar pile squeezing method and system

The invention relates to a method and a system for a high-pressure soil-extruding mortar pile. The method comprises the following steps: a drilling rod is driven to reach the designed elevation of the depth of a soil layer by utilizing a drilling machine or a vibrating pile driving machine; grouting materials are compressed into a soil body gradually from the bottom to up; and the drilling rod is lifted at slow speed, so as to form a coherent mortar pile body. The grouting materials quickly bleed after being compressed out by high pressure, so that the fluidity is reduced; the pile body forms spherical stemlike grouting by pushing the prior soil body to displace and then vacate the space; and the added stress in the soil is manually increased to extrude soil bodies between piles, and the pressure of water in gaps of the soil is improved and is discharged, so that the soil between the piles is extruded to be compact. The system for realizing the method is as follows: a compression system of a compression device is a system which has double cylinders, and absorbs and discharges materials continuously. The method has the advantages of the prior treatment (consolidation treatment and compound treatment) technologies; and various information such as the reclaiming pressure and the flow rate (curve) is digitally displayed in time through a PLC, and extrusion and extension of the diameter of the pile are simulated, so that the method is more favorable for constructors to know about the construction state in time to perform accurate control.
Owner:顾宝洪
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