Probiotic composition for relieving anxiety and depression, regulating bad mood, relieving pressure and helping sleep and preparation method and applications thereof

A technology of probiotic bacteria and composition, applied in the field of probiotic bacteria composition and preparation thereof, can solve the problems of affecting response ability and memory, intestinal dysbiosis, addiction and the like, and achieves improvement of intestinal flora, improvement of sleep quality, Anxiety relief effect

Pending Publication Date: 2019-08-20
GUANGZHOU KANGZE MEDICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The existing anti-anxiety and depression drugs mainly include amitriptyline, doxepin, maprotiline, etc., but most of them are neurological drugs. Long-term use will destroy beneficial intestinal flora, lead to intestinal ecological imbalance, and affect the human body. health and longevity
The existing decompression and sleep aid products mainly include placebos and sleeping pills, but taking placebos can only provide psychological relief, and cannot bring any effect to the patient’s body, and long-term use of sleeping pills will form dependence or addiction, resulting in resistance. Drug properties, even affect the ability to respond and memory, causing mental disorders and depression

Method used

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  • Probiotic composition for relieving anxiety and depression, regulating bad mood, relieving pressure and helping sleep and preparation method and applications thereof
  • Probiotic composition for relieving anxiety and depression, regulating bad mood, relieving pressure and helping sleep and preparation method and applications thereof
  • Probiotic composition for relieving anxiety and depression, regulating bad mood, relieving pressure and helping sleep and preparation method and applications thereof

Examples

Experimental program
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Effect test

preparation example Construction

[0034] The present invention also provides the preparation method of the probiotic composition, comprising the following steps: 1) after drying the fructo-oligosaccharide, resistant dextrin and lactitol respectively, they are mixed to obtain a mixed material; the dried fructo-oligosaccharide, The water activity of resistant dextrin and lactitol ≤ 0.05; 2) mix the mixed material with Lactobacillus acidophilus NCFM, Lactobacillus rhamnosus HN001, lactic acid bacteria compound powder GI, lactic acid bacteria compound powder OH, animal Bifidobacterium B94 , Bifidobacterium bifidum R0071, Lactobacillus casei R0215, live Bacillus coagulans GBI30,6086 and Lactobacillus rhamnosus GG are mixed to obtain a probiotic composition.

[0035] In the present invention, the fructooligosaccharide, resistant dextrin and lactitol are dried separately and mixed to obtain a mixed material. In the present invention, the drying is preferably air drying, the drying times are 2-8 times, the drying temp...

Embodiment 1

[0040] A kind of probiotic composition

[0041] Specifications: 2g / bag

[0042] The formula is shown in Table 1.

[0043] The formula of a kind of probiotic composition of table 1

[0044]

[0045] The live bacteria content of each probiotic in the probiotic composition is shown in Table 2.

[0046] Table 2 Live bacteria content of probiotics

[0047]

[0048] Preparation:

[0049] 1) Take raw materials: 0.205g of fructooligosaccharide, 0.589g of resistant dextrin, 0.57g of lactitol, auxiliary materials: 0.005g of yeast powder and 0.3g of skimmed milk powder, and then test the above-mentioned raw materials and auxiliary materials by a water activity meter Background water activity test;

[0050] 2) Put 0.205g of fructooligosaccharides, 0.589g of resistant dextrin, 0.57g of lactitol, 0.005g of yeast powder and 0.3g of skim milk powder after the background water activity test in step 1) into the oven respectively, and then Low-temperature baking at 35-40°C with circu...

Embodiment 2

[0058] Probiotic composition efficacy detection in embodiment 1

[0059] 1. Object

[0060] 50 volunteers participated in this study voluntarily and signed the informed consent.

[0061] Inclusion criteria:

[0062] Inclusion criteria: ① Pittsburgh Sleep Quality Index (PSQI) score > 7; ② Age 18 to 55; ③ Volunteer to participate in this study and sign an informed consent form.

[0063] Exclusion criteria: ① SDS self-rating depression scale (Self-Rating Depression Scale, SDS) score > 50; ② SAS anxiety self-rating scale (Self-Rating Anxiety Scale, SAS) score > 40; ③ Psychoactive drug abuse and dependence.

[0064] 2. Method

[0065] 1. Research method: The sleep quality of the volunteers was measured, and 50 subjects who met the inclusion criteria were selected, and they were given the probiotic composition in Example 1, and a 30-day comparative test was carried out.

[0066] 2. Evaluation tool: Use the self-made general situation questionnaire to investigate the general demo...

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Abstract

The invention provides a probiotic composition and a preparation method and applications thereof, and belongs to the technical field of health-care foods. The probiotic composition comprises probiotics and prebiotics. The probiotics comprise lactobacillus acidophilus NCFM, lactobacillus rhamnosus HN001, lactic acid bacteria composite powder GI, lactic acid bacteria composite powder OH, bifidobacterium animalis B94, bifidobacterium bifidum R0071, lactobacillus casei R0215, live bacillus coagulans GBI30,6086 and lactobacillus rhamnosus GG. The prebiotics include fructo-oligosaccharides, resistant dextrins and lactitol. The mass ratio of the probiotics to the prebiotics is (300-350):(1300-1400). The total viable bacteria concentration of the probiotics in the probiotics composition is more than or equal to 9.0x10<9> CFU / g. The probiotic composition provided by the invention can obviously improve sleep quality, and significantly relieve anxiety and depression.

Description

technical field [0001] The invention belongs to the technical field of health food, and in particular relates to a probiotic composition for relieving anxiety and depression, regulating emotional deviation, reducing stress and helping sleep, and a preparation method and application thereof. Background technique [0002] With the rapid development of society, the living habits of Chinese people have changed, and the pressure of life has increased, accompanied by a series of health problems such as anxiety, depression, and insomnia. These health problems are potentially harmful. If they are not treated and improved for a long time , will bring great loss to the family and society. [0003] Anxiety insomnia refers to difficulty in falling asleep and frequent awakenings, frequent dreams and easy awakening, difficulty in falling asleep after waking up, and fear after waking up in a dream. It is the most common type of insomnia in clinical practice. The etiology of anxiety insomn...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/125A23L33/135
CPCA23L33/135A23L33/125A23V2002/00A23V2400/147A23V2400/181A23V2400/125A23V2400/113A23V2400/175A23V2400/515A23V2400/517A23V2400/533A23V2200/3202A23V2200/3204A23V2200/322A23V2250/28A23V2250/5114A23V2250/6414
Inventor 易江丰彭永正石川胡少华罗振刊
Owner GUANGZHOU KANGZE MEDICAL TECH CO LTD
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