Lactobacillus paracasei CCFM1069 and application thereof

Abstract

The invention discloses lactobacillus paracasei CCFM1069 and an application thereof. The lactobacillus paracasei CCFM1069 can bear stomach intestine environment of human bodies, notably increase watercontent of excrement and urine, increase the propelling rate of small intestines, shorten the time of discharging a first granule of black stool, reduce the content of peptide YY in serum, raise thelevel of 5-hydroxytryptamine in colon tissue, raise the level of nerve nutrition factors 3 in the colon tissue, reduce Aqp4 genetic transcription level in the colon tissue, increase the number of Cajal interstitial cells in the colon tissue, and increase the content of short chain fatty acids in intestinal tracts; and the lactobacillus paracasei CCFM1069 has high adsorption capacity on pentadecafluorooctanoic acid, has the capacity of relieving PFOA toxicity and has quite good application prospects.

Description

technical field

[0001] The invention belongs to the technical field of microorganisms, and in particular relates to Lactobacillus paracasei CCFM1069 and application thereof. Background technique

[0002] At present, constipation has become one of the main problems plaguing modern people, which affects the emotions of patients and reduces their quality of life and life satisfaction. Many patients are not very satisfied with traditional treatment options, mainly because of their therapeutic effects. Poor. Therefore, present patients and ordinary normal people need an effective method to treat and prevent constipation. From clinical observation, female patients are more numerous than male patients. Among constipation patients in North America, the ratio of females to males is about 2.2:1, and the probability of constipation increases with age, especially after the age of 65. Domestic surveys also show that the occurrence of chronic constipation has obvious regional character...

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