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Medicine for treating gastrointestinal summer damp cold and preparing method thereof

A technology for colds due to summer dampness and medicine, applied in the field of preparation of the medicine, can solve the problems of affecting the curative effect, difficult extraction and retention of active ingredients, etc., and achieve the effects of being difficult to decompose and destroy, maintaining natural characteristics, and having strong separation ability.

Inactive Publication Date: 2004-06-30
INST OF SCI & TECH GUANGDONG UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the current methods of using pure traditional Chinese medicine preparations to treat colds are mostly water decoction or water extraction and alcohol precipitation. The obtained liquid medicine is directly used or processed into the required dosage form, and the volatile parts of the active ingredients in the raw medicine are difficult to retain. , that is to say, it is difficult to extract and retain the active ingredients in the raw materials to the greatest extent, thus affecting the curative effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment ( 1

[0034] 1. Distilling Huoxiang with conventional steam to obtain crude Huoxiang volatile oil;

[0035] 2. Use the molecular distillation device to distill the volatile oil of Huoxiang, refine the volatile oil of Huoxiang, the molecular distillation temperature is 90°C, and the vacuum degree is 200Pa×10 -1 ;

[0036] 3. Grind the dried magnolia officinalis, atractylodes atractylodes and dried ginger into 20-mesh fine powder respectively;

[0037] 4, adopt the model that the magnolia bark powder after the pulverization, herb powder, dried ginger powder are made by Hanwei (HANDWAY) company respectively is that 100ml-SPE supercritical carbon dioxide fluid extraction device extracts effective active substance, and wherein the extraction temperature of magnolia powder is 25°C, extraction pressure is 20mPa, extraction time is 2.5 hours; Atractylodes powder extraction temperature is 55°C, extraction pressure is 30mPa, extraction time is ~1.5 hours; dry ginger powder extraction tempera...

Embodiment ( 2

[0041] 1. Distill Huoxiang with conventional steam to obtain Huoxiang volatile oil;

[0042] 2. Use the molecular distillation device to distill the volatile oil of Huoxiang, refine the volatile oil of Huoxiang, the molecular distillation temperature is 110°C, and the vacuum degree is 400Pa×10 -1 ;

[0043] 3. Grind the dried magnolia officinalis, atractylodes atractylodes and dried ginger into 20-mesh fine powder respectively;

[0044] 4, adopt the model that the magnolia bark powder after the pulverization, herb powder, dried ginger powder are made by Hanwei (HANDWAY) company respectively is that 100ml-SPE supercritical carbon dioxide fluid extraction device extracts effective active substance, and wherein the extraction temperature of magnolia powder is 35℃, the extraction pressure is 25mPa, the extraction time is 1.5 hours; the extraction temperature of the herb powder is 41℃, the extraction pressure is 20mPa, the extraction time is 2.5 hours; the extraction temperature o...

Embodiment ( 3

[0048] 1. Distilling Huoxiang with conventional steam to obtain crude Huoxiang volatile oil;

[0049] 2. Use the molecular distillation device to distill the volatile oil of Huoxiang, refine the volatile oil of Huoxiang, the temperature of molecular distillation is 150°C, and the degree of vacuum is 300Pa×10 -1 ;

[0050] 3. Grind the dried magnolia officinalis, atractylodes atractylodes and dried ginger into 20-mesh fine powder respectively;

[0051] 4, adopt the model that the magnolia bark powder after the pulverization, herb powder, dried ginger powder are made by Hanwei (HANDWAY) company respectively is that 100ml-SPE supercritical carbon dioxide fluid extraction device extracts effective active substance, and wherein the extraction temperature of magnolia powder is 33°C, extraction pressure is 23mPa, extraction time is 2 hours; extraction temperature of Atractylodes herb powder is 53°C, extraction pressure is 27mPa, extraction time is 2 hours; extraction temperature of ...

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Abstract

The present invention discloses a pure Chinese medicine preparation for curing gastrointestinal type summer-heat and dampness common cold and its preparation method. Said invention adopts molecular distillation and supercritical CO2 fluid extraction equipment to extract the effective active substances of agastache / patchouli, magnolia bark, atractylodes root and dried ginger, after the agastache / patchouli extract, magnolia bark extract, atractylodes root extract and dried ginger extract are mixed according to a certain ratio, the medicinal vegetable oil auxiliary material is added, then they are made into the soft capsule by means of drum granule-pressing machine.

Description

1. Technical field: [0001] The invention relates to a medicine for gastrointestinal type summer-damp cold, in particular a Chinese patent medicine prepared from Chinese herbal medicines, and also relates to a preparation method of the medicine. 2. Technical background: [0002] Flu is the modal frequently-occurring disease, and flu often induces diseases such as secondary bronchitis, pneumonia, and threatens human health. The name of cold first appeared in Yang Shiying's "Renzhai Zhizhifang · Zhufeng" in the Northern Song Dynasty, "cold wind pathogens, fever, headache, loud cough, sticky mucus and saliva". Before that, colds were often referred to as "cold", "wind evil" and so on. "Clinical Internal Medicine of Traditional Chinese Medicine" edited by Wang Yongyan and others divides cold syndrome into: wind-cold cold, wind-heat cold, exterior cold and internal heat, summer-damp cold, wind-dryness cold, qi deficiency cold, yang deficiency cold, blood deficiency cold, and yin ...

Claims

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Application Information

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IPC IPC(8): A61P1/00A61P31/00
Inventor 李卫民
Owner INST OF SCI & TECH GUANGDONG UNIV OF CHINESE MEDICINE
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