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Traditional Chinese medicine preparation

A technology of traditional Chinese medicine preparation and yam, which is applied in the field of traditional Chinese medicine, can solve the problems such as unsatisfactory treatment effect, and achieve the effect of improving anti-cervicitis effect, not easy to decompose and destroy, and high extraction efficiency

Inactive Publication Date: 2012-01-25
洪伟
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Cervicitis is a frequent gynecological disease. The general treatment adopts traditional Chinese medicine theory, using some Chinese herbal formulas, combined with oral administration and external application, but the treatment effect is not very satisfactory

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Wash 5 kg of radish and yam with clean water, and then dry them at 50°C. Grind the dried radish and yam into 20-mesh fine powder, and combine the crushed radish and yam with Hanwei ( The 100ml-SPE supercritical carbon dioxide fluid extraction device manufactured by HANDWAY) company extracts lipophilic effective active substances. The extraction temperature is 45°C, the extraction pressure is 30mPa, and the extraction time is 2 hours; the drug residue after supercritical extraction is extracted with alcohol. The hydrophilic effective active substance is extracted by water precipitation method, the volume concentration of ethanol is 75%, and the alcohol extraction temperature is 80°C. Concentrate the alcohol extract to a relative density of 1.2 (at 80°C), add 5.5 times the amount of water, stir well, let stand for 5 hours, filter, take the precipitate and dry it in vacuum at 80°C to obtain a dry extract. Take dry extract with 350g PEG 400 After stirring and dissolving wi...

Embodiment 2

[0021] Wash 6 kg of radish and yam with clean water, and then dry them at 50 ° C. Grind the dried radish and yam into 20-mesh fine powder, and combine the crushed radish and yam with Hanwei ( The 100ml-SPE supercritical carbon dioxide fluid extraction device manufactured by HANDWAY) company extracts lipophilic effective active substances. The extraction temperature is 50°C, the extraction pressure is 25mPa, and the extraction time is 1.5 hours; the drug residue after supercritical extraction is extracted with alcohol. The hydrophilic effective active substance is extracted by water precipitation method, the volume concentration of ethanol is 90%, and the alcohol extraction temperature is 70°C. Concentrate the alcohol extract to a relative density of 1.0 (at 80°C), add 7 times the amount of water, stir well, let stand for 5 hours, filter, take the precipitate and dry it in vacuum at 80°C to obtain a dry extract. Take dry extract with 360g PEG 400 After stirring and dissolving ...

Embodiment 3

[0024] Wash 5 kg of radish and yam with clean water, and then dry them at 50°C. Grind the dried radish and yam into 20-mesh fine powder, and combine the crushed radish and yam with Hanwei ( The 100ml-SPE supercritical carbon dioxide fluid extraction device manufactured by HANDWAY) company extracts lipophilic effective active substances. The extraction temperature is 60°C, the extraction pressure is 28mPa, and the extraction time is 1.5 hours; The hydrophilic effective active substance is extracted by water precipitation method, the volume concentration of ethanol is 90%, and the alcohol extraction temperature is 70°C. Concentrate the alcohol extract to a relative density of 1.0 (at 80°C), add 5 times the amount of water, stir well, let stand for 5 hours, filter, and vacuum-dry the precipitate at 80°C to obtain a dry extract. Take dry extract with 380g PEG 400 After stirring and dissolving with slight heat, add supercritical extract, 60 g of glycerin, and 0.15 g of ethylparabe...

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Abstract

The invention discloses a traditional Chinese medicine preparation which is prepared from the following components in parts by weight: 5-6 parts of Alocasia cucullata and 1-2 parts of Chinese yam. In the invention, a carbon dioxide supercutical fluid extraction device is used for extracting lipophilic effective and active components of Alocasia cucullata and Chinese yam; and thus, the invention has the advantages of high extraction efficiency and no solvent residual toxicity, does not need to respectively make extractum, and can maximally maintain the natural features of the extracts since the natural active components and thermosensitive components can not be easily decomposed and destroyed. The dregs after supercritical extraction are subjected to hydrophilic active component extraction by an alcohol-extraction water-precipitation method, so that the effective components with various properties can be extracted completely. The extraction method disclosed by the invention can sufficiently explore the active components of the active pharmaceutical ingredients, and the obtained active components are very different from the extractum used in the prior art, thereby greatly enhancing the anti-cervicitis effect.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine preparation for treating cervicitis. Background technique [0002] Cervicitis is a common disease in women of childbearing age, there are two kinds of acute and chronic. Acute cervicitis often coexists with acute endometritis or acute vaginitis, but chronic cervicitis is more common. The main manifestations are increased leucorrhea, thick mucus or purulent mucus, sometimes accompanied by bloodshot or bloodshot. Long-term chronic mechanical stimulation is the main cause of cervicitis. Hospital medicine Esni. [0003] Cervicitis is a frequently occurring gynecological disease. The general treatment adopts the theory of traditional Chinese medicine, utilizes some Chinese herbal formulas, and cooperates with oral administration and external application, but the therapeutic effect is not very satisfactory. Contents of the invention [000...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61P15/00
Inventor 洪伟
Owner 洪伟
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