The invention relates to a traditional Chinese medicine composition, a preparation method and an application thereof, and a preparation containing the composition, which belong to the technical field of traditional Chinese medicine pharmacy. The traditional Chinese medicine composition contains the following raw material medicines in parts by weight: 8-15 parts of rhizoma atractylodis, 10-20 parts of areca-nut, 8-15 parts of mangnolia officinalis, 8-15 parts of fruit of immature citron, 8-12 parts of rhizoma acori graminei, 8-15 parts of platycodon grandiflorum, 8-15 parts of common hogfennel root, 8-15 parts of tuckahoe, 8-12 parts of fructus perillae and 8-12 parts of fritillaria, and the traditional Chinese medicine composition is used for treating such symptoms caused by overnutrition, non-scientific feeding and a variety of complicated social and ecological factors as hyperglycemia, hypertension, hyperlipidemia, fatty liver, overweight, constipation, loose stool, abdominal distension, gastrointestinal disorder, insomnia, palpitation, myocardial infarction, cerebral apoplexy, backache and leg pain, amnesia, schizophrenia, impotence, irregular menstruation, infertility and even cancers, and the traditional Chinese medicine composition has the advantages of good curative effect, quick effect, wide disease treatment spectrum, non-toxic side effect, low treatment cost, no rare medicinal herb, simple preparation method, etc.